{"id":"https://openalex.org/W1853845900","doi":"https://doi.org/10.1128/mcb.10.12.6791","title":"Two Related Families of Retrotransposons from Schizosaccharomyces pombe","display_name":"Two Related Families of Retrotransposons from Schizosaccharomyces pombe","publication_year":1990,"publication_date":"1990-12-01","ids":{"openalex":"https://openalex.org/W1853845900","doi":"https://doi.org/10.1128/mcb.10.12.6791","mag":"1853845900","pmid":"https://pubmed.ncbi.nlm.nih.gov/2174117","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/362960"},"language":"en","primary_location":{"id":"doi:10.1128/mcb.10.12.6791","doi":"https://doi.org/10.1128/mcb.10.12.6791","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.10.12.6791","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC359947","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010051653","display_name":"Henry L. Levin","orcid":"https://orcid.org/0000-0003-1728-118X","observed_orcids":["https://orcid.org/0000-0003-1728-118X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H L Levin","raw_affiliation_strings":["Department of Molecular Biology & Genetics, Johns Hopkins School of Medicine, Baltimore, Maryland, 21205"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology & Genetics, Johns Hopkins School of Medicine, Baltimore, Maryland, 21205","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110251870","display_name":"Daniel C. Weaver","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D C Weaver","raw_affiliation_strings":["Department of Molecular Biology & Genetics, Johns Hopkins School of Medicine, Baltimore, Maryland, 21205"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology & Genetics, Johns Hopkins School of Medicine, Baltimore, Maryland, 21205","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075536007","display_name":"Jef D. Boeke","orcid":"https://orcid.org/0000-0001-5322-4946","observed_orcids":["https://orcid.org/0000-0001-5322-4946"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J D Boeke","raw_affiliation_strings":["Department of Molecular Biology & Genetics, Johns Hopkins School of Medicine, Baltimore, Maryland, 21205"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology & Genetics, Johns Hopkins School of Medicine, Baltimore, Maryland, 21205","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.1097,"has_fulltext":false,"cited_by_count":119,"citation_normalized_percentile":{"value":0.94062476,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"12","first_page":"6791","last_page":"6798"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retrotransposons","display_name":"retrotransposons","score":0.9980000257492065},{"id":"https://openalex.org/keywords/schizosaccharomyces-pombe","display_name":"Schizosaccharomyces pombe","score":0.9879999756813049},{"id":"https://openalex.org/keywords/tf1","display_name":"TF1","score":0.6240000128746033},{"id":"https://openalex.org/keywords/transposon-families","display_name":"transposon families","score":0.7139999866485596},{"id":"https://openalex.org/keywords/long-terminal-repeat","display_name":"long terminal repeat","score":0.9700000286102295},{"id":"https://openalex.org/keywords/reverse-transcriptase","display_name":"reverse transcriptase","score":0.7850000262260437},{"id":"https://openalex.org/keywords/integrase","display_name":"integrase","score":0.9259999990463257},{"id":"https://openalex.org/keywords/protease-domain","display_name":"protease domain","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C2779429346","wikidata":"https://www.wikidata.org/wiki/Q2236682","display_name":"Schizosaccharomyces pombe","level":4,"score":0.9210090637207031},{"id":"https://openalex.org/C7029365","wikidata":"https://www.wikidata.org/wiki/Q413988","display_name":"Retrotransposon","level":5,"score":0.9120604991912842},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8868877291679382},{"id":"https://openalex.org/C4918238","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"Transposable element","level":4,"score":0.7602934837341309},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.7462542057037354},{"id":"https://openalex.org/C2776519988","wikidata":"https://www.wikidata.org/wiki/Q1317935","display_name":"Schizosaccharomyces","level":5,"score":0.6581417918205261},{"id":"https://openalex.org/C199491388","wikidata":"https://www.wikidata.org/wiki/Q1869477","display_name":"Long terminal repeat","level":4,"score":0.5871968269348145},{"id":"https://openalex.org/C14430832","wikidata":"https://www.wikidata.org/wiki/Q412550","display_name":"Integrase","level":3,"score":0.5709288120269775},{"id":"https://openalex.org/C156719811","wikidata":"https://www.wikidata.org/wiki/Q28774","display_name":"Reverse transcriptase","level":4,"score":0.4504103660583496},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4350017309188843},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.22557303309440613},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2114936113357544},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.13832464814186096}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004251","descriptor_name":"DNA Transposable Elements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004271","descriptor_name":"DNA, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004271","descriptor_name":"DNA, Fungal","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D005800","descriptor_name":"Genes, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012091","descriptor_name":"Repetitive Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012331","descriptor_name":"RNA, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012568","descriptor_name":"Schizosaccharomyces","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015183","descriptor_name":"Restriction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1128/mcb.10.12.6791","doi":"https://doi.org/10.1128/mcb.10.12.6791","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.10.12.6791","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},{"id":"doi:10.1128/mcb.10.12.6791-6798.1990","doi":"https://doi.org/10.1128/mcb.10.12.6791-6798.1990","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.10.12.6791-6798.1990","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:26060","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC359947","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:359947","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/359947","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Biol","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:362960","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/362960","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Biol","raw_type":"Text"},{"id":"pmid:2174117","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2174117","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular biology","raw_type":"Comparative Study"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:26060","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC359947","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5584530978","display_name":"Program on Molecular and Cellular Mechanisms of Tumorigenesis","funder_award_id":"P01CA016519","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W28812364","https://openalex.org/W1025333691","https://openalex.org/W1554644662","https://openalex.org/W1582561043","https://openalex.org/W1819474806","https://openalex.org/W1933609030","https://openalex.org/W1941003312","https://openalex.org/W1966405914","https://openalex.org/W1970970321","https://openalex.org/W1973643623","https://openalex.org/W1979140780","https://openalex.org/W1980585800","https://openalex.org/W1981114271","https://openalex.org/W1983812589","https://openalex.org/W1987599394","https://openalex.org/W1997110527","https://openalex.org/W1999506587","https://openalex.org/W2000254114","https://openalex.org/W2005663625","https://openalex.org/W2009766806","https://openalex.org/W2010400841","https://openalex.org/W2020461380","https://openalex.org/W2024938036","https://openalex.org/W2032776824","https://openalex.org/W2034694342","https://openalex.org/W2035416711","https://openalex.org/W2039325177","https://openalex.org/W2043983280","https://openalex.org/W2045848136","https://openalex.org/W2048124712","https://openalex.org/W2051172007","https://openalex.org/W2055012503","https://openalex.org/W2061054814","https://openalex.org/W2067296939","https://openalex.org/W2083378882","https://openalex.org/W2089971545","https://openalex.org/W2096377604","https://openalex.org/W2110925400","https://openalex.org/W2138270253","https://openalex.org/W2145980370","https://openalex.org/W2296278740"],"related_works":["https://openalex.org/W2019526440","https://openalex.org/W3150704146","https://openalex.org/W1928329139","https://openalex.org/W858909386","https://openalex.org/W2077910124","https://openalex.org/W2060579568","https://openalex.org/W2064868905","https://openalex.org/W161344049","https://openalex.org/W3199738902","https://openalex.org/W2065748300"],"abstract_inverted_index":{"Two":[0],"related":[1],"families":[2],"of":[3,17,30,36,42,51,74,82,91,102,108],"transposons":[4],"were":[5],"isolated":[6],"from":[7],"schizosaccharomyces":[8],"pombe,":[9],"an":[10],"organism":[11],"which":[12,21],"has":[13],"been":[14],"the":[15,28,67,100],"object":[16],"extensive":[18],"genetic":[19],"studies":[20],"had":[22],"previously":[23],"produced":[24],"no":[25],"evidence":[26],"for":[27,118],"existence":[29],"such":[31],"elements.":[32],"These":[33],"two":[34],"classes":[35],"repeated":[37],"DNAs,":[38],"dubbed":[39],"Tf1":[40,53,83,109],"(transposon":[41],"fission":[43],"yeast":[44],"1)":[45],"and":[46,54,61,71,79,84,112],"Tf2":[47,55,85],"have":[48],"many":[49],"properties":[50],"retrotransposons.":[52],"both":[56],"possess":[57],"long":[58],"terminal":[59],"repeats":[60],"predicted":[62],"protein":[63],"sequences":[64],"that":[65,114],"resemble":[66],"protease,":[68],"reverse":[69],"transcriptase,":[70],"integrase":[72],"domains":[73],"retroviruses.":[75],"The":[76,94,105],"chromosomal":[77],"locations":[78],"total":[80],"numbers":[81],"differ":[86],"greatly":[87],"in":[88,99],"various":[89],"isolates":[90],"S.":[92],"pombe.":[93],"Tf":[95],"elements":[96],"are":[97],"expressed":[98],"form":[101],"4.5-kb":[103],"mRNAs.":[104],"complete":[106],"sequence":[107],"was":[110],"determined":[111],"suggests":[113],"a":[115],"novel":[116],"mechanism":[117],"regulating":[119],"its":[120],"gene":[121],"expression":[122],"may":[123],"be":[124],"used.":[125]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}