{"id":"https://openalex.org/W1853150423","doi":"https://doi.org/10.1128/cvi.00170-15","title":"Herpes Simplex Virus 1 Suppresses the Function of Lung Dendritic Cells via Caveolin-1","display_name":"Herpes Simplex Virus 1 Suppresses the Function of Lung Dendritic Cells via Caveolin-1","publication_year":2015,"publication_date":"2015-05-28","ids":{"openalex":"https://openalex.org/W1853150423","doi":"https://doi.org/10.1128/cvi.00170-15","mag":"1853150423","pmid":"https://pubmed.ncbi.nlm.nih.gov/26018534","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4519715"},"language":"en","primary_location":{"id":"doi:10.1128/cvi.00170-15","doi":"https://doi.org/10.1128/cvi.00170-15","is_oa":true,"landing_page_url":"https://doi.org/10.1128/cvi.00170-15","pdf_url":"https://cvi.asm.org/content/cdli/22/8/883.full.pdf","source":{"id":"https://openalex.org/S114575275","display_name":"Clinical and Vaccine Immunology","issn_l":"1556-679X","issn":["1556-679X","1556-6811"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-100"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Vaccine Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://cvi.asm.org/content/cdli/22/8/883.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027159356","display_name":"Bing Wu","orcid":"https://orcid.org/0000-0003-1656-3783","observed_orcids":["https://orcid.org/0000-0003-1656-3783"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Wu","raw_affiliation_strings":["State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101670175","display_name":"Shuang Geng","orcid":"https://orcid.org/0000-0002-7566-6398","observed_orcids":["https://orcid.org/0000-0002-7566-6398"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuang Geng","raw_affiliation_strings":["Key Laboratory of Medical Molecular Virology of MOH and MOE, Fudan University Shanghai Medical College, Shanghai, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Medical Molecular Virology of MOH and MOE, Fudan University Shanghai Medical College, Shanghai, People's Republic of China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015853514","display_name":"Yanmin Bi","orcid":"https://orcid.org/0009-0009-9281-4207","observed_orcids":["https://orcid.org/0009-0009-9281-4207"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanmin Bi","raw_affiliation_strings":["State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hu Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hu Liu","raw_affiliation_strings":["State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080273554","display_name":"Yanxin Hu","orcid":"https://orcid.org/0000-0001-7009-8451","observed_orcids":["https://orcid.org/0000-0001-7009-8451"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanxin Hu","raw_affiliation_strings":["College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101938009","display_name":"Xinqiang Li","orcid":"https://orcid.org/0000-0002-4193-4227","observed_orcids":["https://orcid.org/0000-0002-4193-4227"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinqiang Li","raw_affiliation_strings":["State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101789838","display_name":"Yizhi Zhang","orcid":"https://orcid.org/0009-0002-4427-3003","observed_orcids":["https://orcid.org/0009-0002-4427-3003","https://orcid.org/0009-0000-5586-5886"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yizhi Zhang","raw_affiliation_strings":["State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086672406","display_name":"Xiaoyu Zhou","orcid":"https://orcid.org/0000-0002-2304-4191","observed_orcids":["https://orcid.org/0000-0002-2304-4191","https://orcid.org/0009-0005-8556-9814"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyu Zhou","raw_affiliation_strings":["Key Laboratory of Medical Molecular Virology of MOH and MOE, Fudan University Shanghai Medical College, Shanghai, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Medical Molecular Virology of MOH and MOE, Fudan University Shanghai Medical College, Shanghai, People's Republic of China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103859705","display_name":"Guoxing Zheng","orcid":"https://orcid.org/0000-0002-1296-8727","observed_orcids":["https://orcid.org/0000-0002-1296-8727"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guoxing Zheng","raw_affiliation_strings":["Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101494989","display_name":"Bin He","orcid":"https://orcid.org/0000-0001-7385-5542","observed_orcids":["https://orcid.org/0000-0001-7385-5542"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bin He","raw_affiliation_strings":["Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100324087","display_name":"Bin Wang","orcid":"https://orcid.org/0000-0002-9945-1818","observed_orcids":["https://orcid.org/0000-0002-9945-1818","https://orcid.org/0000-0003-3981-8849"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Wang","raw_affiliation_strings":["Key Laboratory of Medical Molecular Virology of MOH and MOE, Fudan University Shanghai Medical College, Shanghai, People's Republic of China","State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Medical Molecular Virology of MOH and MOE, Fudan University Shanghai Medical College, Shanghai, People's Republic of China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"raw_affiliation_string":"State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I52158045"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5796,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.58248738,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"22","issue":"8","first_page":"883","last_page":"895"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12793","display_name":"Caveolin-1 and cellular processes","score":0.6182000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12793","display_name":"Caveolin-1 and cellular processes","score":0.6182000041007996,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.2865999937057495,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/caveolin-1","display_name":"caveolin-1","score":0.996999979019165},{"id":"https://openalex.org/keywords/caveolae","display_name":"caveolae","score":0.949999988079071},{"id":"https://openalex.org/keywords/lung-dendritic-cells","display_name":"lung dendritic cells","score":0.8889999985694885},{"id":"https://openalex.org/keywords/inducible-nitric-oxide-synthase","display_name":"inducible nitric oxide synthase","score":0.9570000171661377},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9900000095367432},{"id":"https://openalex.org/keywords/virus-host-interactions","display_name":"host-virus interaction","score":0.6539999842643738},{"id":"https://openalex.org/keywords/pulmonary-pathology","display_name":"lung pathology","score":0.5}],"concepts":[{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.7665553092956543},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5274522304534912},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.525611162185669},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5010421276092529},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.47562721371650696},{"id":"https://openalex.org/C2781399669","wikidata":"https://www.wikidata.org/wiki/Q1509095","display_name":"Simplexvirus","level":5,"score":0.451216459274292},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4068458676338196},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3338874578475952},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3218924403190613},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24984848499298096},{"id":"https://openalex.org/C2776409557","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Herpesviridae","level":4,"score":0.1887379288673401},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08140036463737488},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.057115018367767334}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007108","descriptor_name":"Immune Tolerance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051242","descriptor_name":"Caveolin 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D052247","descriptor_name":"Nitric Oxide Synthase Type II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1128/cvi.00170-15","doi":"https://doi.org/10.1128/cvi.00170-15","is_oa":true,"landing_page_url":"https://doi.org/10.1128/cvi.00170-15","pdf_url":"https://cvi.asm.org/content/cdli/22/8/883.full.pdf","source":{"id":"https://openalex.org/S114575275","display_name":"Clinical and Vaccine Immunology","issn_l":"1556-679X","issn":["1556-679X","1556-6811"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-100"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Vaccine Immunology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3695956","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4519715","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:26018534","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26018534","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and vaccine immunology : CVI","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4519715","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4519715/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Vaccine Immunol","raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/10780802","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Herpes_Simplex_Virus_1_Suppresses_the_Function_of_Lung_Dendritic_Cells_via_Caveolin-1_/10780802","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1128/cvi.00170-15","doi":"https://doi.org/10.1128/cvi.00170-15","is_oa":true,"landing_page_url":"https://doi.org/10.1128/cvi.00170-15","pdf_url":"https://cvi.asm.org/content/cdli/22/8/883.full.pdf","source":{"id":"https://openalex.org/S114575275","display_name":"Clinical and Vaccine Immunology","issn_l":"1556-679X","issn":["1556-679X","1556-6811"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-100"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Vaccine Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320241","display_name":"Academy of Medical Sciences","ror":"https://ror.org/00c489v88"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"},{"id":"https://openalex.org/F4320323137","display_name":"Chinese Academy of Medical Sciences","ror":"https://ror.org/03cve4549"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1853150423.pdf"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W157540157","https://openalex.org/W1535423179","https://openalex.org/W1575798288","https://openalex.org/W1661249704","https://openalex.org/W1880220168","https://openalex.org/W1880225328","https://openalex.org/W1897849704","https://openalex.org/W1927872630","https://openalex.org/W1965335584","https://openalex.org/W1965837098","https://openalex.org/W1970788572","https://openalex.org/W1973302772","https://openalex.org/W1973708518","https://openalex.org/W1973753526","https://openalex.org/W1987004269","https://openalex.org/W1992174226","https://openalex.org/W1992809394","https://openalex.org/W1994806440","https://openalex.org/W1997001042","https://openalex.org/W2017510263","https://openalex.org/W2018091769","https://openalex.org/W2018362725","https://openalex.org/W2019336094","https://openalex.org/W2021826830","https://openalex.org/W2026870422","https://openalex.org/W2045121093","https://openalex.org/W2055318948","https://openalex.org/W2059169597","https://openalex.org/W2060194295","https://openalex.org/W2060220048","https://openalex.org/W2067169557","https://openalex.org/W2075592687","https://openalex.org/W2076653031","https://openalex.org/W2076753860","https://openalex.org/W2078710631","https://openalex.org/W2085197897","https://openalex.org/W2086765939","https://openalex.org/W2092191659","https://openalex.org/W2093019667","https://openalex.org/W2093813481","https://openalex.org/W2097467678","https://openalex.org/W2106059490","https://openalex.org/W2106199356","https://openalex.org/W2106768960","https://openalex.org/W2116610565","https://openalex.org/W2117198458","https://openalex.org/W2118662525","https://openalex.org/W2119377963","https://openalex.org/W2119534221","https://openalex.org/W2122569992","https://openalex.org/W2131043061","https://openalex.org/W2131745475","https://openalex.org/W2133192252","https://openalex.org/W2138285726","https://openalex.org/W2150668138","https://openalex.org/W2150725220","https://openalex.org/W2151868358","https://openalex.org/W2155785814","https://openalex.org/W2158045229","https://openalex.org/W2159031916","https://openalex.org/W2159868932","https://openalex.org/W2163444331","https://openalex.org/W2164239879","https://openalex.org/W2167935134","https://openalex.org/W2169039001","https://openalex.org/W2409784260"],"related_works":["https://openalex.org/W4378716556","https://openalex.org/W4386748849","https://openalex.org/W2118662525","https://openalex.org/W4280497361","https://openalex.org/W1994070664","https://openalex.org/W7097066193","https://openalex.org/W2115718472","https://openalex.org/W1965837098","https://openalex.org/W2155706994","https://openalex.org/W2899797411"],"abstract_inverted_index":{"Caveolin-1":[0],"(Cav-1),":[1],"the":[2,26,48,57,112,138,173],"principal":[3],"structural":[4],"protein":[5],"of":[6,14,28,50,59,80,103,137],"caveolae,":[7],"has":[8],"been":[9,40],"implicated":[10],"as":[11,164],"a":[12,71,165,185],"regulator":[13,167],"virus-host":[15],"interactions.":[16],"Several":[17],"viruses":[18],"exploit":[19],"caveolae":[20,151],"to":[21,76,110,114,135,171],"facilitate":[22],"viral":[23],"infections.":[24,193],"However,":[25],"roles":[27],"Cav-1":[29,46,73,106,120,144,163,182],"in":[30,63,99,150,152],"herpes":[31],"simplex":[32],"virus":[33,81],"1":[34],"(HSV-1)":[35],"infection":[36],"have":[37],"not":[38],"fully":[39],"elucidated.":[41],"Here,":[42],"we":[43],"report":[44],"that":[45,136,143],"downregulates":[47],"expression":[49],"inducible":[51],"nitric":[52,60],"oxide":[53,61],"synthase":[54],"(iNOS)":[55],"and":[56,82,96,148],"production":[58,98],"(NO)":[62],"dendritic":[64],"cells":[65],"(DCs)":[66],"during":[67],"HSV-1":[68,88,149,170],"infection.":[69,89],"As":[70],"result,":[72],"deficiency":[74],"led":[75],"an":[77,127],"accelerated":[78],"elimination":[79],"less":[83],"lung":[84],"pathological":[85],"change":[86],"following":[87],"This":[90],"protection":[91,113],"was":[92,108],"dependent":[93],"on":[94],"iNOS":[95,128,147],"NO":[97,179],"DCs.":[100],"Adoptive":[101],"transfer":[102],"DCs":[104],"with":[105,126,146],"knockdown":[107],"sufficient":[109],"confer":[111],"wild-type":[115],"(WT)":[116],"mice.":[117],"In":[118],"addition,":[119],"knockout":[121],"(KO)":[122],"(Cav-1(-/-))":[123],"mice":[124],"treated":[125],"inhibitor":[129],"exhibited":[130],"significantly":[131],"reduced":[132],"survival":[133],"compared":[134],"nontreated":[139],"controls.":[140],"We":[141],"found":[142],"colocalized":[145],"HSV-1-infected":[153],"DCs,":[154],"suggesting":[155],"their":[156],"interaction.":[157],"Taken":[158],"together,":[159],"our":[160],"results":[161],"identified":[162],"novel":[166],"utilized":[168],"by":[169,178],"evade":[172],"host":[174],"antiviral":[175],"response":[176],"mediated":[177],"production.":[180],"Therefore,":[181],"might":[183],"be":[184],"valuable":[186],"target":[187],"for":[188],"therapeutic":[189],"approaches":[190],"against":[191],"herpesvirus":[192]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}