{"id":"https://openalex.org/W1850806629","doi":null,"title":"A review of POEMS syndrome.","display_name":"A review of POEMS syndrome.","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W1850806629","mag":"1850806629","pmid":"https://pubmed.ncbi.nlm.nih.gov/24624542"},"language":"en","primary_location":{"id":"pmid:24624542","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24624542","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology (Williston Park, N.Y.)","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000308170","display_name":"Angela A. Dispenzieri","orcid":"https://orcid.org/0000-0001-8780-9512","observed_orcids":["https://orcid.org/0000-0001-8780-9512"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Angela Dispenzieri","raw_affiliation_strings":["Hematology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012403700","display_name":"Francis K. Buadi","orcid":"https://orcid.org/0000-0003-3214-0203","observed_orcids":["https://orcid.org/0000-0003-3214-0203"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francis K Buadi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6202,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.93120594,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"27","issue":"12","first_page":"1242","last_page":"50"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11627","display_name":"Autoimmune Neurological Disorders and Treatments","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/poems-syndrome","display_name":"POEMS syndrome","score":1.0},{"id":"https://openalex.org/keywords/paraneoplastic-syndrome","display_name":"paraneoplastic syndrome","score":0.9010000228881836},{"id":"https://openalex.org/keywords/plasma-cell-dyscrasia","display_name":"plasma cell dyscrasia","score":0.8690000176429749},{"id":"https://openalex.org/keywords/polyradiculoneuropathy","display_name":"polyradiculoneuropathy","score":0.9599999785423279},{"id":"https://openalex.org/keywords/monoclonal-gammopathy","display_name":"monoclonal gammopathy","score":0.8069999814033508},{"id":"https://openalex.org/keywords/endocrine-disorders","display_name":"endocrine disorders","score":0.7289999723434448},{"id":"https://openalex.org/keywords/organomegaly","display_name":"organomegaly","score":0.7749999761581421},{"id":"https://openalex.org/keywords/skin-changes","display_name":"skin changes","score":0.5680000185966492},{"id":"https://openalex.org/keywords/papilledema","display_name":"papilledema","score":0.9409999847412109},{"id":"https://openalex.org/keywords/sclerotic-bone-lesions","display_name":"sclerotic bone lesions","score":0.7720000147819519},{"id":"https://openalex.org/keywords/thrombocytosis","display_name":"thrombocytosis","score":0.8700000047683716},{"id":"https://openalex.org/keywords/erythrocytosis","display_name":"erythrocytosis","score":0.902999997138977},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.968999981880188},{"id":"https://openalex.org/keywords/lenalidomide","display_name":"lenalidomide","score":0.9049999713897705},{"id":"https://openalex.org/keywords/bortezomib","display_name":"bortezomib","score":1.0},{"id":"https://openalex.org/keywords/alkylating-agents","display_name":"alkylating agents","score":0.8769999742507935},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C2776210965","wikidata":"https://www.wikidata.org/wiki/Q2553422","display_name":"POEMS syndrome","level":3,"score":0.9666450023651123},{"id":"https://openalex.org/C2778551932","wikidata":"https://www.wikidata.org/wiki/Q285115","display_name":"Organomegaly","level":3,"score":0.9405232071876526},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8599123358726501},{"id":"https://openalex.org/C2779788118","wikidata":"https://www.wikidata.org/wiki/Q1542410","display_name":"Thrombocytosis","level":3,"score":0.667364239692688},{"id":"https://openalex.org/C2775892965","wikidata":"https://www.wikidata.org/wiki/Q1502312","display_name":"Polyneuropathy","level":2,"score":0.6292009353637695},{"id":"https://openalex.org/C2776063141","wikidata":"https://www.wikidata.org/wiki/Q425681","display_name":"Lenalidomide","level":3,"score":0.6099718809127808},{"id":"https://openalex.org/C2776367607","wikidata":"https://www.wikidata.org/wiki/Q953049","display_name":"Papilledema","level":2,"score":0.6021522879600525},{"id":"https://openalex.org/C2777025900","wikidata":"https://www.wikidata.org/wiki/Q29725","display_name":"Vascular endothelial growth factor","level":3,"score":0.5355958938598633},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5335662364959717},{"id":"https://openalex.org/C2777478702","wikidata":"https://www.wikidata.org/wiki/Q419319","display_name":"Bortezomib","level":3,"score":0.4972982704639435},{"id":"https://openalex.org/C2777052087","wikidata":"https://www.wikidata.org/wiki/Q3395796","display_name":"Polyradiculoneuropathy","level":3,"score":0.45963746309280396},{"id":"https://openalex.org/C2776396001","wikidata":"https://www.wikidata.org/wiki/Q250694","display_name":"Plasma cell","level":3,"score":0.45265620946884155},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.44079574942588806},{"id":"https://openalex.org/C2779609412","wikidata":"https://www.wikidata.org/wiki/Q203174","display_name":"Thalidomide","level":3,"score":0.4297224283218384},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4282413423061371},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29492542147636414},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.2821148931980133},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27901798486709595},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.26529544591903687},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2594326138496399},{"id":"https://openalex.org/C167734588","wikidata":"https://www.wikidata.org/wiki/Q4356503","display_name":"VEGF receptors","level":2,"score":0.13591653108596802},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.0},{"id":"https://openalex.org/C2778691916","wikidata":"https://www.wikidata.org/wiki/Q205214","display_name":"Guillain-Barre syndrome","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016878","descriptor_name":"POEMS Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D016878","descriptor_name":"POEMS Syndrome","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:24624542","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24624542","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology (Williston Park, N.Y.)","raw_type":"Journal Article"},{"id":"mag:1850806629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24624542","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7141654144","display_name":"Measles Virotherapy for Multiple Myeloma","funder_award_id":"R01CA168719","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7640049654","display_name":"Prevalence and Progression of Monoclonal Gammopathies","funder_award_id":"R01CA107476","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":77,"referenced_works":["https://openalex.org/W93023005","https://openalex.org/W96902332","https://openalex.org/W141492214","https://openalex.org/W150778959","https://openalex.org/W1528918582","https://openalex.org/W1965977684","https://openalex.org/W1966868722","https://openalex.org/W1971290010","https://openalex.org/W1971416647","https://openalex.org/W1974547871","https://openalex.org/W1974785629","https://openalex.org/W1975521996","https://openalex.org/W1975852558","https://openalex.org/W1980171506","https://openalex.org/W1981313177","https://openalex.org/W1982154014","https://openalex.org/W1983182895","https://openalex.org/W1986606467","https://openalex.org/W1988186308","https://openalex.org/W1995486690","https://openalex.org/W1999943742","https://openalex.org/W2002085529","https://openalex.org/W2009069105","https://openalex.org/W2013802257","https://openalex.org/W2024554365","https://openalex.org/W2026920764","https://openalex.org/W2027742754","https://openalex.org/W2027879458","https://openalex.org/W2032048924","https://openalex.org/W2034798596","https://openalex.org/W2039717141","https://openalex.org/W2039724386","https://openalex.org/W2040978620","https://openalex.org/W2043503880","https://openalex.org/W2046840192","https://openalex.org/W2049043216","https://openalex.org/W2051556891","https://openalex.org/W2052565014","https://openalex.org/W2054888616","https://openalex.org/W2055500870","https://openalex.org/W2061108137","https://openalex.org/W2061738284","https://openalex.org/W2064281577","https://openalex.org/W2064346179","https://openalex.org/W2067316902","https://openalex.org/W2075068942","https://openalex.org/W2075115086","https://openalex.org/W2075681466","https://openalex.org/W2077646176","https://openalex.org/W2079628952","https://openalex.org/W2081971650","https://openalex.org/W2083594310","https://openalex.org/W2084253838","https://openalex.org/W2091342521","https://openalex.org/W2092597335","https://openalex.org/W2094686973","https://openalex.org/W2099271973","https://openalex.org/W2101870371","https://openalex.org/W2105421621","https://openalex.org/W2106597626","https://openalex.org/W2115241394","https://openalex.org/W2120301560","https://openalex.org/W2121956456","https://openalex.org/W2123789589","https://openalex.org/W2124941404","https://openalex.org/W2131385585","https://openalex.org/W2135609466","https://openalex.org/W2153786474","https://openalex.org/W2153947189","https://openalex.org/W2164129225","https://openalex.org/W2166161087","https://openalex.org/W2172192704","https://openalex.org/W2327395669","https://openalex.org/W2336888115","https://openalex.org/W2407376088","https://openalex.org/W2411597300","https://openalex.org/W2471959588"],"related_works":["https://openalex.org/W4230207869","https://openalex.org/W2902590250","https://openalex.org/W2009069105","https://openalex.org/W3083652165","https://openalex.org/W2278680844","https://openalex.org/W4310177445","https://openalex.org/W1969104100","https://openalex.org/W4225150445","https://openalex.org/W3212177369","https://openalex.org/W4237998216"],"abstract_inverted_index":{"POEMS":[0,34,84],"syndrome":[1,6],"is":[2,8,61,69,105,117,123],"a":[3],"rare":[4],"paraneoplastic":[5],"that":[7],"caused":[9],"by":[10],"an":[11,54,111],"underlying":[12],"plasma":[13,24],"cell":[14,25,95],"disorder.":[15],"Its":[16],"main":[17],"features":[18],"include":[19,35,85],"polyradiculoneuropathy,":[20],"organomegaly,":[21],"endocrinopathy,":[22],"monoclonal":[23],"disorder,":[26],"and":[27,43,60,87,98,120],"skin":[28],"changes.":[29],"Other":[30],"important":[31,55],"characteristics":[32],"of":[33,102],"papilledema,":[36],"extravascular":[37],"volume":[38],"overload,":[39],"sclerotic":[40],"bone":[41],"lesions,":[42],"thrombocytosis/erythrocytosis":[44],"(PEST).":[45],"Vascular":[46],"endothelial":[47],"growth":[48],"factor":[49,74],"(VEGF)":[50],"appears":[51],"to":[52],"play":[53],"role":[56,101],"in":[57],"the":[58,72,76,115],"disease":[59],"especially":[62],"useful":[63],"for":[64,83],"monitoring":[65],"therapy,":[66],"but":[67],"it":[68],"not":[70],"likely":[71],"sole":[73],"driving":[75],"disease.":[77],"The":[78,100],"most":[79],"commonly":[80],"used":[81],"therapies":[82],"alkylators":[86],"steroids,":[88],"high-dose":[89],"chemotherapy":[90],"with":[91],"peripheral":[92],"blood":[93],"stem":[94],"transplantation,":[96],"lenalidomide,":[97],"bortezomib.":[99],"anti-VEGF":[103],"antibodies":[104],"uncertain.":[106],"In":[107],"general,":[108],"patients":[109],"have":[110],"excellent":[112],"prognosis":[113],"if":[114],"diagnosis":[116],"made":[118],"early":[119],"appropriate":[121],"therapy":[122],"applied.":[124]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}