{"id":"https://openalex.org/W1850604657","doi":"https://doi.org/10.1016/s0016-5085(11)62899-0","title":"Hypoxia and Gut Neuroendocrine Cells: The Role of HIF-1\u03b1, Nf\u03baB and Serotonin Production From Enterochromaffin Cells in Intestinal Ischemia","display_name":"Hypoxia and Gut Neuroendocrine Cells: The Role of HIF-1\u03b1, Nf\u03baB and Serotonin Production From Enterochromaffin Cells in Intestinal Ischemia","publication_year":2011,"publication_date":"2011-05-01","ids":{"openalex":"https://openalex.org/W1850604657","doi":"https://doi.org/10.1016/s0016-5085(11)62899-0","mag":"1850604657"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(11)62899-0","doi":"https://doi.org/10.1016/s0016-5085(11)62899-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(11)62899-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063977364","display_name":"Maria Br\u00f8nstad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Br\u00f8nstad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030287499","display_name":"Bernhard Svejda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bernhard Svejda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008921503","display_name":"Roswitha Pfragner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roswitha Pfragner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086888726","display_name":"Bj\u00f6rn Inge Gustafsson","orcid":"https://orcid.org/0000-0001-7031-2294","observed_orcids":["https://orcid.org/0000-0001-7031-2294"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bjorn I. Gustafsson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009119423","display_name":"Mark S. Kidd","orcid":"https://orcid.org/0000-0002-1525-5167","observed_orcids":["https://orcid.org/0000-0002-1525-5167"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Kidd","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5040553082","display_name":"Erik Sollig\u00e5rd","orcid":"https://orcid.org/0000-0001-6173-3580","observed_orcids":["https://orcid.org/0000-0001-6173-3580"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erik Solligard","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":0.3264,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.64744688,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"140","issue":"5","first_page":"S","last_page":"698"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11625","display_name":"Abdominal vascular conditions and treatments","score":0.8442000150680542,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11625","display_name":"Abdominal vascular conditions and treatments","score":0.8442000150680542,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.042500000447034836,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12237","display_name":"Congenital gastrointestinal and neural anomalies","score":0.0142000000923872,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intestinal-hypoxia","display_name":"intestinal hypoxia","score":0.8169999718666077},{"id":"https://openalex.org/keywords/intestinal-ischemia","display_name":"intestinal ischemia","score":0.8289999961853027},{"id":"https://openalex.org/keywords/enterochromaffin-cells","display_name":"enterochromaffin cells","score":0.9150000214576721},{"id":"https://openalex.org/keywords/hif-1alpha","display_name":"HIF-1\u03b1","score":0.9950000047683716},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.8849999904632568},{"id":"https://openalex.org/keywords/serotonin-synthesis","display_name":"serotonin synthesis","score":0.7680000066757202},{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.8700000047683716},{"id":"https://openalex.org/keywords/ikkbeta","display_name":"IKK\u03b2","score":0.6740000247955322},{"id":"https://openalex.org/keywords/ki-67","display_name":"Ki-67","score":0.7960000038146973},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.6269999742507935},{"id":"https://openalex.org/keywords/glut1","display_name":"GLUT1","score":0.5199999809265137},{"id":"https://openalex.org/keywords/igf-ii","display_name":"insulin-like growth factor II","score":0.8899999856948853},{"id":"https://openalex.org/keywords/trefoil-factor-3","display_name":"TFF3","score":0.8389999866485596},{"id":"https://openalex.org/keywords/hypoperfusion","display_name":"hypoperfusion","score":0.4790000021457672}],"concepts":[{"id":"https://openalex.org/C90423213","wikidata":"https://www.wikidata.org/wiki/Q568290","display_name":"Enterochromaffin cell","level":4,"score":0.8105685114860535},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.6103813648223877},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.5873591303825378},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5470484495162964},{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.5371715426445007},{"id":"https://openalex.org/C2777730290","wikidata":"https://www.wikidata.org/wiki/Q411114","display_name":"NF-\u03baB","level":3,"score":0.45669418573379517},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.428849995136261},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.425539493560791},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.41170206665992737},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3955737352371216},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36379343271255493},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3571036756038666},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.27470844984054565},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2592439651489258},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.25077173113822937},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.2394571602344513},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23268061876296997},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.16029810905456543},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1476878821849823},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12817132472991943},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(11)62899-0","doi":"https://doi.org/10.1016/s0016-5085(11)62899-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(11)62899-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1925138693","https://openalex.org/W1537170274","https://openalex.org/W2091401724","https://openalex.org/W2073549523","https://openalex.org/W4293473055","https://openalex.org/W2380136708","https://openalex.org/W4232851609","https://openalex.org/W4251711902","https://openalex.org/W3166708761","https://openalex.org/W1431827665"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}