{"id":"https://openalex.org/W1841269736","doi":"https://doi.org/10.1039/c5ja00303b","title":"Evaluation of sample preparation methods for single cell quantitative elemental imaging using proton or synchrotron radiation focused beams","display_name":"Evaluation of sample preparation methods for single cell quantitative elemental imaging using proton or synchrotron radiation focused beams","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1841269736","doi":"https://doi.org/10.1039/c5ja00303b","mag":"1841269736"},"language":"en","primary_location":{"id":"doi:10.1039/c5ja00303b","doi":"https://doi.org/10.1039/c5ja00303b","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c5ja00303b","pdf_url":null,"source":{"id":"https://openalex.org/S26602194","display_name":"Journal of Analytical Atomic Spectrometry","issn_l":"0267-9477","issn":["0267-9477","1364-5544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Analytical Atomic Spectrometry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082448876","display_name":"Laura Perrin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I15057530","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530"]},{"id":"https://openalex.org/I4210125595","display_name":"Laboratoire de Physique des deux infinis Bordeaux","ror":"https://ror.org/034a4bk84","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"id":"https://openalex.org/I4210133362","display_name":"Institut National de Physique Nucl\u00e9aire et de Physique des Particules","ror":"https://ror.org/03fd77x13","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210133362"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laura Perrin","raw_affiliation_strings":["CENBG","France","Gradignan","UMR 5797","University of Bordeaux","CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","University of Bordeaux, CENBG, UMR 5797, Gradignan, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CENBG","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"France","institution_ids":[]},{"raw_affiliation_string":"Gradignan","institution_ids":[]},{"raw_affiliation_string":"UMR 5797","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"University of Bordeaux","institution_ids":["https://openalex.org/I15057530"]},{"raw_affiliation_string":"CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"raw_affiliation_string":"University of Bordeaux, CENBG, UMR 5797, Gradignan, France","institution_ids":["https://openalex.org/I15057530","https://openalex.org/I4210125595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088610050","display_name":"Asunci\u00f3n Carmona","orcid":"https://orcid.org/0000-0002-9253-4581","observed_orcids":["https://orcid.org/0000-0002-9253-4581"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I15057530","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530"]},{"id":"https://openalex.org/I4210125595","display_name":"Laboratoire de Physique des deux infinis Bordeaux","ror":"https://ror.org/034a4bk84","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"id":"https://openalex.org/I4210133362","display_name":"Institut National de Physique Nucl\u00e9aire et de Physique des Particules","ror":"https://ror.org/03fd77x13","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210133362"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Asuncion Carmona","raw_affiliation_strings":["CENBG","France","Gradignan","UMR 5797","University of Bordeaux","CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","University of Bordeaux, CENBG, UMR 5797, Gradignan, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CENBG","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"France","institution_ids":[]},{"raw_affiliation_string":"Gradignan","institution_ids":[]},{"raw_affiliation_string":"UMR 5797","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"University of Bordeaux","institution_ids":["https://openalex.org/I15057530"]},{"raw_affiliation_string":"CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"raw_affiliation_string":"University of Bordeaux, CENBG, UMR 5797, Gradignan, France","institution_ids":["https://openalex.org/I15057530","https://openalex.org/I4210125595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070170703","display_name":"St\u00e9phane Roudeau","orcid":"https://orcid.org/0000-0002-4539-9380","observed_orcids":["https://orcid.org/0000-0002-4539-9380"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I15057530","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530"]},{"id":"https://openalex.org/I4210125595","display_name":"Laboratoire de Physique des deux infinis Bordeaux","ror":"https://ror.org/034a4bk84","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"id":"https://openalex.org/I4210133362","display_name":"Institut National de Physique Nucl\u00e9aire et de Physique des Particules","ror":"https://ror.org/03fd77x13","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210133362"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phane Roudeau","raw_affiliation_strings":["CENBG","France","Gradignan","UMR 5797","University of Bordeaux","CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","University of Bordeaux, CENBG, UMR 5797, Gradignan, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CENBG","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"France","institution_ids":[]},{"raw_affiliation_string":"Gradignan","institution_ids":[]},{"raw_affiliation_string":"UMR 5797","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"University of Bordeaux","institution_ids":["https://openalex.org/I15057530"]},{"raw_affiliation_string":"CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"raw_affiliation_string":"University of Bordeaux, CENBG, UMR 5797, Gradignan, France","institution_ids":["https://openalex.org/I15057530","https://openalex.org/I4210125595"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054143636","display_name":"Richard Ortega","orcid":"https://orcid.org/0000-0003-1692-5406","observed_orcids":["https://orcid.org/0000-0003-1692-5406"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I15057530","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530"]},{"id":"https://openalex.org/I4210125595","display_name":"Laboratoire de Physique des deux infinis Bordeaux","ror":"https://ror.org/034a4bk84","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"id":"https://openalex.org/I4210133362","display_name":"Institut National de Physique Nucl\u00e9aire et de Physique des Particules","ror":"https://ror.org/03fd77x13","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210133362"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Richard Ortega","raw_affiliation_strings":["CENBG","France","Gradignan","UMR 5797","University of Bordeaux","CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","University of Bordeaux, CENBG, UMR 5797, Gradignan, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CENBG","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"France","institution_ids":[]},{"raw_affiliation_string":"Gradignan","institution_ids":[]},{"raw_affiliation_string":"UMR 5797","institution_ids":["https://openalex.org/I4210125595"]},{"raw_affiliation_string":"University of Bordeaux","institution_ids":["https://openalex.org/I15057530"]},{"raw_affiliation_string":"CNRS, IN2P3, CENBG, UMR 5797 Gradignan France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210125595","https://openalex.org/I4210133362"]},{"raw_affiliation_string":"University of Bordeaux, CENBG, UMR 5797, Gradignan, France","institution_ids":["https://openalex.org/I15057530","https://openalex.org/I4210125595"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5054143636"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I4210125595","https://openalex.org/I4210133362"],"apc_list":null,"apc_paid":null,"fwci":7.0691,"has_fulltext":false,"cited_by_count":95,"citation_normalized_percentile":{"value":0.97459212,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"30","issue":"12","first_page":"2525","last_page":"2532"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11733","display_name":"X-ray Spectroscopy and Fluorescence Analysis","score":0.5810999870300293,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11733","display_name":"X-ray Spectroscopy and Fluorescence Analysis","score":0.5810999870300293,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11183","display_name":"Advanced X-ray Imaging Techniques","score":0.12080000340938568,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12166","display_name":"Ion-surface interactions and analysis","score":0.0989999994635582,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sample-preparation","display_name":"sample preparation","score":0.9330000281333923},{"id":"https://openalex.org/keywords/micro-pixe","display_name":"micro-PIXE","score":0.9480000138282776},{"id":"https://openalex.org/keywords/synchrotron-radiation","display_name":"synchrotron radiation","score":0.8320000171661377},{"id":"https://openalex.org/keywords/neurons","display_name":"neurons","score":0.8899999856948853},{"id":"https://openalex.org/keywords/sample-preparation-optimization","display_name":"sample preparation optimization","score":0.4580000042915344}],"concepts":[{"id":"https://openalex.org/C16332341","wikidata":"https://www.wikidata.org/wiki/Q212871","display_name":"Synchrotron radiation","level":2,"score":0.73820561170578},{"id":"https://openalex.org/C2778576202","wikidata":"https://www.wikidata.org/wiki/Q2540164","display_name":"Sample preparation","level":2,"score":0.6571053862571716},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.628467321395874},{"id":"https://openalex.org/C64885871","wikidata":"https://www.wikidata.org/wiki/Q2533665","display_name":"Elemental analysis","level":2,"score":0.5558732151985168},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.5127049684524536},{"id":"https://openalex.org/C54516573","wikidata":"https://www.wikidata.org/wiki/Q2294","display_name":"Proton","level":2,"score":0.4772617518901825},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.3350057601928711},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.26685160398483276},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2312052845954895},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.09756991267204285},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07409155368804932},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.056881070137023926},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1039/c5ja00303b","doi":"https://doi.org/10.1039/c5ja00303b","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c5ja00303b","pdf_url":null,"source":{"id":"https://openalex.org/S26602194","display_name":"Journal of Analytical Atomic Spectrometry","issn_l":"0267-9477","issn":["0267-9477","1364-5544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Analytical Atomic Spectrometry","raw_type":"journal-article"},{"id":"pmh:oai:HAL:hal-02899701v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-02899701","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Analytical Atomic Spectrometry, 2015, 30 (12), pp.2525-2532. ⟨10.1039/C5JA00303B⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:oskar-bordeaux.fr:20.500.12278/119891","doi":null,"is_oa":false,"landing_page_url":"https://oskar-bordeaux.fr/handle/20.500.12278/119891","pdf_url":null,"source":{"id":"https://openalex.org/S4306402569","display_name":"Oskar-Bordeaux (Universite de Bordeaux)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I15057530","host_organization_name":"Universit\u00e9 de Bordeaux","host_organization_lineage":["https://openalex.org/I15057530"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article de revue"},{"id":"pmh:oai:oskar-bordeaux.fr:20.500.12278/136965","doi":null,"is_oa":false,"landing_page_url":"https://oskar-bordeaux.fr/handle/20.500.12278/136965","pdf_url":null,"source":{"id":"https://openalex.org/S4306402569","display_name":"Oskar-Bordeaux (Universite de Bordeaux)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I15057530","host_organization_name":"Universit\u00e9 de Bordeaux","host_organization_lineage":["https://openalex.org/I15057530"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article de revue"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G155593175","display_name":"Chemical Nano-Imaging of the Dopaminergic Cell","funder_award_id":"ANR-09-PIRI-0029","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320887","display_name":"European Synchrotron Radiation Facility","ror":"https://ror.org/02550n020"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320323712","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W634137984","https://openalex.org/W1481510250","https://openalex.org/W1977412307","https://openalex.org/W1983139535","https://openalex.org/W1989985197","https://openalex.org/W2003016828","https://openalex.org/W2021512296","https://openalex.org/W2022173646","https://openalex.org/W2026053208","https://openalex.org/W2026537696","https://openalex.org/W2031382438","https://openalex.org/W2037632846","https://openalex.org/W2037645243","https://openalex.org/W2046834353","https://openalex.org/W2053849251","https://openalex.org/W2058007143","https://openalex.org/W2058161966","https://openalex.org/W2061463538","https://openalex.org/W2064727418","https://openalex.org/W2077030104","https://openalex.org/W2081032856","https://openalex.org/W2091760058","https://openalex.org/W2098417372","https://openalex.org/W2100600922","https://openalex.org/W2106541390","https://openalex.org/W2114635825","https://openalex.org/W2128293999","https://openalex.org/W2129223126","https://openalex.org/W2137367053","https://openalex.org/W2167807896","https://openalex.org/W2323781912","https://openalex.org/W2327226531","https://openalex.org/W4231885856"],"related_works":["https://openalex.org/W2014939656","https://openalex.org/W3003124811","https://openalex.org/W4291262884","https://openalex.org/W1969184759","https://openalex.org/W1972224007","https://openalex.org/W2029480253","https://openalex.org/W2167807896","https://openalex.org/W4411495296","https://openalex.org/W4321373007","https://openalex.org/W1965000840"],"abstract_inverted_index":{"Sample":[0],"preparation":[1],"protocols":[2],"for":[3,18],"single":[4],"cell":[5],"quantitative":[6],"elemental":[7],"imaging":[8],"using":[9],"micro-PIXE":[10],"or":[11],"micro-SXRF":[12],"have":[13],"been":[14],"compared":[15],"and":[16],"optimized":[17],"neuronal":[19],"cells.":[20]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":26},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}