{"id":"https://openalex.org/W1839613638","doi":"https://doi.org/10.18632/oncotarget.1652","title":"Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation","display_name":"Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation","publication_year":2014,"publication_date":"2014-01-27","ids":{"openalex":"https://openalex.org/W1839613638","doi":"https://doi.org/10.18632/oncotarget.1652","mag":"1839613638","pmid":"https://pubmed.ncbi.nlm.nih.gov/24504219","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3964228"},"language":"en","primary_location":{"id":"doi:10.18632/oncotarget.1652","doi":"https://doi.org/10.18632/oncotarget.1652","is_oa":true,"landing_page_url":"https://doi.org/10.18632/oncotarget.1652","pdf_url":"https://www.oncotarget.com/article/1652/pdf/","source":{"id":"https://openalex.org/S126644158","display_name":"Oncotarget","issn_l":"1949-2553","issn":["1949-2553"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncotarget","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.oncotarget.com/article/1652/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Zhi-Qiang Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Zhi-Qiang Wang","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","Department of Molecular Medicine, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]},{"raw_affiliation_string":"Department of Molecular Medicine, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I43406934"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053934915","display_name":"Magdalena Bachvarova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Magdalena Bachvarova","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019869174","display_name":"Chantale Morin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Chantale Morin","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087341200","display_name":"Marie Plante","orcid":"https://orcid.org/0000-0002-2298-7913","observed_orcids":["https://orcid.org/0000-0002-2298-7913"]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marie Plante","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I43406934"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jean Gregoire","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jean Gregoire","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I43406934"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022422757","display_name":"Marie\u2010Claude Renaud","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marie-Claude Renaud","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I43406934"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038025657","display_name":"Alexandra Sebastianelli","orcid":"https://orcid.org/0009-0004-5620-6507","observed_orcids":["https://orcid.org/0009-0004-5620-6507"]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alexandra Sebastianelli","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I43406934"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091028771","display_name":"Dimcho R Bachvarov","orcid":"https://orcid.org/0000-0001-6509-9599","observed_orcids":["https://orcid.org/0000-0001-6509-9599"]},"institutions":[{"id":"https://openalex.org/I4210121051","display_name":"H\u00f4tel-Dieu de Qu\u00e9bec","ror":"https://ror.org/034sbqc84","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210121051","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Dimcho Bachvarov","raw_affiliation_strings":["Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","Department of Molecular Medicine, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de recherche du CHU de Qu\u00e9bec, L'H\u00f4tel-Dieu de Qu\u00e9bec, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I4210121051"]},{"raw_affiliation_string":"Department of Molecular Medicine, Laval University, Qu\u00e9bec (Qu\u00e9bec), Canada","institution_ids":["https://openalex.org/I43406934"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5091028771"],"corresponding_institution_ids":["https://openalex.org/I4210121051","https://openalex.org/I43406934"],"apc_list":null,"apc_paid":null,"fwci":3.7485,"has_fulltext":true,"cited_by_count":83,"citation_normalized_percentile":{"value":0.95066951,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"5","issue":"2","first_page":"544","last_page":"560"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9560999870300293,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9560999870300293,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.042500000447034836,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/galnt3","display_name":"GALNT3","score":0.9879999756813049},{"id":"https://openalex.org/keywords/epithelial-ovarian-cancer","display_name":"epithelial ovarian cancer","score":0.9919999837875366},{"id":"https://openalex.org/keywords/mucin-o-glycosylation","display_name":"mucin O-glycosylation","score":0.9440000057220459},{"id":"https://openalex.org/keywords/muc1","display_name":"MUC1","score":0.9049999713897705},{"id":"https://openalex.org/keywords/dna-hypomethylation","display_name":"DNA hypomethylation","score":0.9340000152587891},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.8069999814033508},{"id":"https://openalex.org/keywords/tumor-invasion-and-metastasis","display_name":"tumor invasion and metastasis","score":0.7279999852180481},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.6299999952316284},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.7409999966621399},{"id":"https://openalex.org/keywords/s-phase-arrest","display_name":"S phase arrest","score":0.9269999861717224},{"id":"https://openalex.org/keywords/beta-catenin","display_name":"\u03b2-catenin","score":0.7799999713897705},{"id":"https://openalex.org/keywords/e-cadherin","display_name":"E-cadherin","score":1.0},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.7719749808311462},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6026878952980042},{"id":"https://openalex.org/C150173356","wikidata":"https://www.wikidata.org/wiki/Q6144101","display_name":"Serous fluid","level":2,"score":0.5456434488296509},{"id":"https://openalex.org/C2780084626","wikidata":"https://www.wikidata.org/wiki/Q11793790","display_name":"Ovarian tumor","level":4,"score":0.4915219247341156},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.47668004035949707},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.475963294506073},{"id":"https://openalex.org/C179264091","wikidata":"https://www.wikidata.org/wiki/Q410862","display_name":"Mucin","level":2,"score":0.430480033159256},{"id":"https://openalex.org/C2779256057","wikidata":"https://www.wikidata.org/wiki/Q16909647","display_name":"Tumor progression","level":3,"score":0.4294492304325104},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.42626094818115234},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4021272659301758},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39598536491394043},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38898223638534546},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35943639278411865},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.24930992722511292},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.240779310464859},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09202766418457031}],"mesh":[{"descriptor_ui":"D000077216","descriptor_name":"Carcinoma, Ovarian Epithelial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097763","descriptor_name":"Polypeptide N-acetylgalactosaminyltransferase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009077","descriptor_name":"Mucins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017350","descriptor_name":"N-Acetylgalactosaminyltransferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017350","descriptor_name":"N-Acetylgalactosaminyltransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046888","descriptor_name":"Tissue Array Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048708","descriptor_name":"Cell Growth Processes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.18632/oncotarget.1652","doi":"https://doi.org/10.18632/oncotarget.1652","is_oa":true,"landing_page_url":"https://doi.org/10.18632/oncotarget.1652","pdf_url":"https://www.oncotarget.com/article/1652/pdf/","source":{"id":"https://openalex.org/S126644158","display_name":"Oncotarget","issn_l":"1949-2553","issn":["1949-2553"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncotarget","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2942926","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3964228","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24504219","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24504219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncotarget","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3964228","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3964228/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncotarget","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.791.1155","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.791.1155","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/c3/79/oncotarget-05-544.PMC3964228.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.18632/oncotarget.1652","doi":"https://doi.org/10.18632/oncotarget.1652","is_oa":true,"landing_page_url":"https://doi.org/10.18632/oncotarget.1652","pdf_url":"https://www.oncotarget.com/article/1652/pdf/","source":{"id":"https://openalex.org/S126644158","display_name":"Oncotarget","issn_l":"1949-2553","issn":["1949-2553"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncotarget","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311169","display_name":"Cancer Research Society","ror":"https://ror.org/00t38a349"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1839613638.pdf","grobid_xml":"https://content.openalex.org/works/W1839613638.grobid-xml"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W32715354","https://openalex.org/W170685917","https://openalex.org/W1561773985","https://openalex.org/W1964644808","https://openalex.org/W1965386425","https://openalex.org/W1970698543","https://openalex.org/W1972506570","https://openalex.org/W1977070332","https://openalex.org/W1977831674","https://openalex.org/W1978342819","https://openalex.org/W1979538859","https://openalex.org/W1982273343","https://openalex.org/W1984004506","https://openalex.org/W1988125845","https://openalex.org/W1990532910","https://openalex.org/W1991273312","https://openalex.org/W1997140903","https://openalex.org/W2003885329","https://openalex.org/W2006096506","https://openalex.org/W2008541344","https://openalex.org/W2012675371","https://openalex.org/W2013603554","https://openalex.org/W2027172549","https://openalex.org/W2032091934","https://openalex.org/W2038792980","https://openalex.org/W2039805273","https://openalex.org/W2040380803","https://openalex.org/W2040481717","https://openalex.org/W2040935952","https://openalex.org/W2041808159","https://openalex.org/W2042868850","https://openalex.org/W2043196909","https://openalex.org/W2044342281","https://openalex.org/W2049436594","https://openalex.org/W2053823503","https://openalex.org/W2058384954","https://openalex.org/W2074189907","https://openalex.org/W2074654885","https://openalex.org/W2075060074","https://openalex.org/W2076591667","https://openalex.org/W2079061387","https://openalex.org/W2079605173","https://openalex.org/W2081507143","https://openalex.org/W2087339901","https://openalex.org/W2089791370","https://openalex.org/W2091727244","https://openalex.org/W2091873740","https://openalex.org/W2093221417","https://openalex.org/W2093398117","https://openalex.org/W2094488761","https://openalex.org/W2101691277","https://openalex.org/W2103888354","https://openalex.org/W2108168031","https://openalex.org/W2121711294","https://openalex.org/W2127294807","https://openalex.org/W2128868545","https://openalex.org/W2134860457","https://openalex.org/W2137548222","https://openalex.org/W2138605813","https://openalex.org/W2140740264","https://openalex.org/W2141410747","https://openalex.org/W2142837807","https://openalex.org/W2145271723","https://openalex.org/W2150136461","https://openalex.org/W2152875643","https://openalex.org/W2154438952","https://openalex.org/W2154544743","https://openalex.org/W2155884268","https://openalex.org/W2157197884","https://openalex.org/W2157461726","https://openalex.org/W2158734599","https://openalex.org/W2169035833","https://openalex.org/W2169976220","https://openalex.org/W2325549052","https://openalex.org/W2409684799","https://openalex.org/W2470365486","https://openalex.org/W4250969231","https://openalex.org/W4256602221","https://openalex.org/W6645923845"],"related_works":["https://openalex.org/W7099606833","https://openalex.org/W2339875460","https://openalex.org/W2805032793","https://openalex.org/W2763819270","https://openalex.org/W2944539202","https://openalex.org/W2410106343","https://openalex.org/W2599809618","https://openalex.org/W2384821857","https://openalex.org/W2094971952","https://openalex.org/W6966842152"],"abstract_inverted_index":{"//":[0,72],"Zhi-Qiang":[1],"Wang":[2],"1,2":[3,32],",":[4,8,12,16,20,24,28],"Magdalena":[5],"Bachvarova":[6],"2":[7,11,43],"Chantale":[9],"Morin":[10],"Marie":[13],"Plante":[14],"2,3":[15,19,23,27],"Jean":[17],"Gregoire":[18],"Marie-Claude":[21],"Renaud":[22],"Alexandra":[25],"Sebastianelli":[26],"and":[29,61,119,186,200,205,208,217,231,289,328,337],"Dimcho":[30,69],"Bachvarov":[31],"1":[33],"Department":[34,58],"of":[35,59,172,183,265,272,283,303,321],"Molecular":[36],"Medicine,":[37],"Laval":[38,63],"University,":[39,64],"Qu\u00e9bec":[40,54,65],"(Qu\u00e9bec),":[41,55,66],"Canada":[42,56,67],"Centre":[44],"de":[45,49,52],"recherche":[46],"du":[47],"CHU":[48],"Qu\u00e9bec,":[50,53],"L\u2019H\u00f4tel-Dieu":[51],"3":[57,109],"Obstetrics":[60],"Gynecology,":[62],"Correspondence:":[68],"Bachvarov,":[70],"email:":[71],"Keywords":[73],":":[74,87,92,97],"GALNT3,":[75],"epithelial":[76,123,163],"ovarian":[77,124,129,148,164,225],"cancer;":[78],"DNA":[79],"hypomethylation,":[80],"progression-free":[81,158],"survival,":[82],"microarrays,":[83],"mucin":[84,356],"O-glycosylation":[85,357],"Received":[86],"December":[88],"3,":[89],"2013":[90],"Accepted":[91],"January":[93,98],"25,":[94],"2014":[95,100],"Published":[96],"27,":[99],"Abstract":[101],"Previously,":[102],"we":[103,132],"have":[104],"identified":[105],"the":[106,151,173,266,284,301,304,322],"polypeptide":[107],"N-acetylgalactosaminyltransferase":[108],"(GALNT3)":[110],"gene":[111,324],"as":[112,144,214,332],"notably":[113],"hypomethylated":[114],"in":[115,139,162,176,224,258,297,307,325],"low-malignant":[116],"potential":[117,320],"(LMP)":[118],"high-grade":[120],"(HG)":[121],"serous":[122,141],"tumors,":[125],"compared":[126,145],"to":[127,146,180,221,235,263,270,351],"normal":[128,147],"tissues.":[130],"Here":[131],"show":[133],"that":[134,346],"GALNT3":[135,152,174,193,239,249,273,276,323,347],"is":[136],"strongly":[137],"overexpressed":[138],"HG":[140],"EOC":[142,177,197,228,259,308,327,335,339,352],"tumors":[143],"tissue.":[149],"Moreover,":[150,248],"expression":[153,175,203,257],"significantly":[154,195],"correlated":[155],"with":[156,168,253,281],"shorter":[157],"survival":[159],"(PFS)":[160],"intervals":[161],"cancer":[165],"(EOC)":[166],"patients":[167],"advanced":[169,326],"disease.":[170],"Knockdown":[171],"cells":[178],"led":[179],"sharp":[181],"decrease":[182],"cell":[184,189,198,285],"proliferation":[185],"induced":[187],"S-phase":[188],"cycle":[190],"arrest.":[191],"Additionally,":[192],"suppression":[194],"inhibited":[196],"migration":[199],"invasion.":[201,309],"Gene":[202],"profiling":[204],"consecutive":[206],"network":[207],"pathway":[209],"analyses":[210],"confirmed":[211],"these":[212],"findings,":[213],"numerous":[215],"genes":[216,245],"pathways":[218],"known":[219],"previously":[220],"be":[222,236],"implicated":[223],"tumorigenesis,":[226],"including":[227],"tumor":[229,243],"invasion":[230],"metastasis,":[232],"were":[233,246],"found":[234],"downregulated":[237],"upon":[238],"suppression,":[240],"while":[241],"some":[242],"suppressor":[244],"induced.":[247],"downregulation":[250],"was":[251,278],"associated":[252],"reduced":[254],"MUC1":[255,267,296],"protein":[256,268],"cells,":[260],"probably":[261],"related":[262],"destabilization":[264],"due":[269],"lack":[271],"glycosylation":[274],"activity.":[275],"knockdown":[277],"also":[279,344],"accompanied":[280],"increase":[282],"adhesion":[286],"molecules":[287],"\u03b2-catenin":[288],"E-cadherin,":[290],"which":[291],"are":[292,314],"normally":[293],"suppressed":[294],"by":[295],"cancer,":[298],"thus":[299],"supporting":[300],"role":[302],"GALNT3-MUC1":[305],"axis":[306],"Taken":[310],"together,":[311],"our":[312],"data":[313],"indicative":[315],"for":[316],"a":[317,333],"strong":[318],"oncogenic":[319],"identify":[329],"this":[330],"transferase":[331],"novel":[334],"biomarker":[336],"putative":[338],"therapeutic":[340],"target.":[341],"Our":[342],"findings":[343],"suggest":[345],"overexpression":[348],"might":[349],"contribute":[350],"progression":[353],"through":[354],"aberrant":[355]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}