{"id":"https://openalex.org/W1838533005","doi":"https://doi.org/10.1200/jco.1998.16.3.1112","title":"Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi's sarcoma.","display_name":"Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi's sarcoma.","publication_year":1998,"publication_date":"1998-03-01","ids":{"openalex":"https://openalex.org/W1838533005","doi":"https://doi.org/10.1200/jco.1998.16.3.1112","mag":"1838533005","pmid":"https://pubmed.ncbi.nlm.nih.gov/9508198"},"language":"en","primary_location":{"id":"doi:10.1200/jco.1998.16.3.1112","doi":"https://doi.org/10.1200/jco.1998.16.3.1112","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.1998.16.3.1112","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111511507","display_name":"Lauri Welles","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L Welles","raw_affiliation_strings":["HIV and AIDS Malignancy Branch, National Cancer Institute; the Warren G. Magnuson Clinical Center, Bethesda, MD 20892-1906, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV and AIDS Malignancy Branch, National Cancer Institute; the Warren G. Magnuson Clinical Center, Bethesda, MD 20892-1906, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108212738","display_name":"M. Wayne Saville","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M W Saville","raw_affiliation_strings":["the Warren G. Magnuson Clinical Center, Bethesda, MD 20892-1906, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Warren G. Magnuson Clinical Center, Bethesda, MD 20892-1906, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005897689","display_name":"Jill Lietzau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Lietzau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055830608","display_name":"James M. Pluda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J M Pluda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074208719","display_name":"Kathleen M. Wyvill","orcid":"https://orcid.org/0000-0003-4285-9887","observed_orcids":["https://orcid.org/0000-0003-4285-9887"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K M Wyvill","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112779111","display_name":"Illinois Feuerstein","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Feuerstein","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079418869","display_name":"William Douglas Figg","orcid":"https://orcid.org/0000-0003-2428-5613","observed_orcids":["https://orcid.org/0000-0003-2428-5613"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W D Figg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111718623","display_name":"Richard M. Lush","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Lush","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112230400","display_name":"Jeanne Odom","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Odom","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049385918","display_name":"Wyndham Hopkins Wilson","orcid":"https://orcid.org/0000-0002-2862-9711","observed_orcids":["https://orcid.org/0000-0002-2862-9711"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W H Wilson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065422525","display_name":"Manuel Fajardo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M T Fajardo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111643690","display_name":"R.W. Humphrey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R W Humphrey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050399316","display_name":"Ellen G. Feigal","orcid":"https://orcid.org/0000-0002-7634-6003","observed_orcids":["https://orcid.org/0000-0002-7634-6003"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Feigal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016816358","display_name":"David P. Tuck","orcid":"https://orcid.org/0000-0001-7313-5158","observed_orcids":["https://orcid.org/0000-0001-7313-5158"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Tuck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044239219","display_name":"Seth M. Steinberg","orcid":"https://orcid.org/0000-0002-8280-551X","observed_orcids":["https://orcid.org/0000-0002-8280-551X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S M Steinberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109632620","display_name":"S Broder","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Broder","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5041169651","display_name":"Robert Yarchoan","orcid":"https://orcid.org/0000-0002-3057-1395","observed_orcids":["https://orcid.org/0000-0002-3057-1395"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Yarchoan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.1814,"has_fulltext":false,"cited_by_count":173,"citation_normalized_percentile":{"value":0.95863618,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"16","issue":"3","first_page":"1112","last_page":"1121"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paclitaxel","display_name":"paclitaxel","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hiv-associated-kaposi-s-sarcoma","display_name":"HIV-associated Kaposi's sarcoma","score":0.9950000047683716},{"id":"https://openalex.org/keywords/dose-titration","display_name":"dose titration","score":0.9259999990463257},{"id":"https://openalex.org/keywords/filgrastim","display_name":"filgrastim","score":0.699999988079071},{"id":"https://openalex.org/keywords/neutropenia","display_name":"neutropenia","score":0.8999999761581421},{"id":"https://openalex.org/keywords/pulmonary-kaposi-s-sarcoma","display_name":"pulmonary Kaposi's sarcoma","score":0.8840000033378601},{"id":"https://openalex.org/keywords/anthracycline-refractory-disease","display_name":"anthracycline-refractory disease","score":0.9010000228881836},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8109999895095825},{"id":"https://openalex.org/keywords/chemotherapy-toxicity","display_name":"chemotherapy toxicity","score":0.5199999809265137},{"id":"https://openalex.org/keywords/cd4-count","display_name":"CD4 count","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8689472675323486},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.7510354518890381},{"id":"https://openalex.org/C2777292972","wikidata":"https://www.wikidata.org/wiki/Q423762","display_name":"Paclitaxel","level":3,"score":0.6023626923561096},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5915820002555847},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5114306807518005},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.47494128346443176},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.42844825983047485},{"id":"https://openalex.org/C2779236070","wikidata":"https://www.wikidata.org/wiki/Q725345","display_name":"Kaposi's sarcoma","level":4,"score":0.4234715402126312},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4184536933898926},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.34453368186950684},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.23094752430915833},{"id":"https://openalex.org/C3018958071","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Human herpesvirus","level":3,"score":0.1427176594734192},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.08451417088508606}],"mesh":[{"descriptor_ui":"D000069585","descriptor_name":"Filgrastim","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000163","descriptor_name":"Acquired Immunodeficiency Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012514","descriptor_name":"Sarcoma, Kaposi","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012514","descriptor_name":"Sarcoma, Kaposi","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016179","descriptor_name":"Granulocyte Colony-Stimulating Factor","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017239","descriptor_name":"Paclitaxel","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017239","descriptor_name":"Paclitaxel","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D017239","descriptor_name":"Paclitaxel","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1200/jco.1998.16.3.1112","doi":"https://doi.org/10.1200/jco.1998.16.3.1112","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.1998.16.3.1112","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmid:9508198","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9508198","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical oncology : official journal of the American Society of Clinical Oncology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320337376","display_name":"NIH Clinical Center","ror":"https://ror.org/04vfsmv21"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W45866251","https://openalex.org/W60886306","https://openalex.org/W118686632","https://openalex.org/W1568104635","https://openalex.org/W1758017998","https://openalex.org/W1804199929","https://openalex.org/W1846163577","https://openalex.org/W1880426265","https://openalex.org/W1962046702","https://openalex.org/W1962493215","https://openalex.org/W1971653559","https://openalex.org/W1985460342","https://openalex.org/W2007503737","https://openalex.org/W2010013604","https://openalex.org/W2026414247","https://openalex.org/W2028840705","https://openalex.org/W2029409133","https://openalex.org/W2032438721","https://openalex.org/W2040562771","https://openalex.org/W2045121497","https://openalex.org/W2053026268","https://openalex.org/W2057481372","https://openalex.org/W2058840267","https://openalex.org/W2065537276","https://openalex.org/W2066957976","https://openalex.org/W2080123851","https://openalex.org/W2106016270","https://openalex.org/W2118873545","https://openalex.org/W2155710042","https://openalex.org/W2171127982","https://openalex.org/W2235063564","https://openalex.org/W2240623839","https://openalex.org/W2315652496","https://openalex.org/W2410536088"],"related_works":["https://openalex.org/W2045121497","https://openalex.org/W2608102667","https://openalex.org/W2018989052","https://openalex.org/W1782134579","https://openalex.org/W2923482678","https://openalex.org/W112793872","https://openalex.org/W2081258495","https://openalex.org/W1999480618","https://openalex.org/W2069507043","https://openalex.org/W2397816855"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"investigate":[2],"the":[3,59,126,166,222,230],"antitumor":[4],"activity":[5,195],"and":[6,107,179,188,226],"safety":[7],"of":[8,68,115,125,158],"paclitaxel":[9,84],"in":[10,205],"patients":[11,25,33,128,138,149,182,206],"with":[12,26,129,207],"advanced":[13,27,197],"human":[14],"immunodeficiency":[15],"virus":[16],"(HIV)-associated":[17],"Kaposi's":[18],"sarcoma":[19],"(KS).":[20],"PATIENTS":[21],"AND":[22],"METHODS:":[23],"Twenty-nine":[24],"HIV-associated":[28,198],"KS":[29,131,199],"were":[30,34],"enrolled.":[31],"The":[32],"overall":[35],"quite":[36],"immunosuppressed":[37],"(median":[38],"CD4":[39],"count,":[40],"15":[41],"cells/microL).":[42],"Paclitaxel":[43,192],"was":[44,61,165],"initially":[45],"administered":[46,85],"at":[47],"135":[48],"mg/m2":[49],"over":[50,86],"3":[51,54],"hours":[52],"every":[53],"weeks":[55],"without":[56],"filgrastim":[57,81],"support;":[58],"dose":[60],"increased":[62],"as":[63,133,200],"tolerated":[64],"to":[65,74,122,153,220],"a":[66,111,155,201],"maximum":[67],"175":[69],"mg/m2.":[70],"Patients":[71],"who":[72,139,150,211],"failed":[73],"respond":[75],"or":[76,83,210],"progressed":[77],"could":[78],"then":[79],"receive":[80,154],"support":[82],"96":[87],"hours.":[88],"RESULTS:":[89],"Of":[90,147],"28":[91],"assessable":[92,137],"patients,":[93],"20":[94],"had":[95,140,161,212],"major":[96,112,162],"responses":[97,100],"(18":[98],"partial":[99],"[PRs],":[101],"one":[102,108,189],"clinical":[103],"complete":[104],"response":[105,113],"[CR],":[106],"CR),":[109],"for":[110,145,234],"rate":[114],"71.4%":[116],"(95%":[117],"confidence":[118],"interval":[119],"[CI],":[120],"51.3%":[121],"86.8%).":[123],"Each":[124],"five":[127,160],"pulmonary":[130,208],"responded,":[132],"did":[134],"all":[135],"four":[136],"previously":[141,213],"received":[142,214],"anthracycline":[143],"therapy":[144],"KS.":[146],"six":[148],"went":[151],"on":[152],"96-hour":[156],"infusion":[157],"paclitaxel,":[159],"responses.":[163],"Neutropenia":[164],"most":[167],"frequent":[168],"dose-limiting":[169],"toxicity;":[170],"possible":[171],"novel":[172],"toxicities":[173],"included":[174],"late":[175,177],"fevers,":[176],"rash,":[178],"eosinophilia.":[180],"Two":[181],"developed":[183],"an":[184],"elevated":[185],"creatinine":[186],"concentration":[187],"cardiomyopathy.":[190],"CONCLUSION:":[191],"has":[193],"substantial":[194],"against":[196],"single":[202],"agent,":[203],"even":[204],"involvement":[209],"anthracyclines.":[215],"Further":[216],"research":[217],"is":[218],"needed":[219],"define":[221],"optimal":[223],"treatment":[224],"schedule":[225],"its":[227],"role":[228],"vis-a-vis":[229],"other":[231],"available":[232],"therapies":[233],"this":[235],"disease.":[236]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}