{"id":"https://openalex.org/W1836337289","doi":"https://doi.org/10.1039/c5ra16352h","title":"Direct, non-amplified detection of microRNA-134 in plasma from epilepsy patients","display_name":"Direct, non-amplified detection of microRNA-134 in plasma from epilepsy patients","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1836337289","doi":"https://doi.org/10.1039/c5ra16352h","mag":"1836337289"},"language":"en","primary_location":{"id":"doi:10.1039/c5ra16352h","doi":"https://doi.org/10.1039/c5ra16352h","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c5ra16352h","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084137874","display_name":"Elaine Spain","orcid":"https://orcid.org/0000-0001-9086-7713","observed_orcids":["https://orcid.org/0000-0001-9086-7713"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]},{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Elaine Spain","raw_affiliation_strings":["Department of Physiology and Medical Physics","Dublin 2","Ireland","Royal College of Surgeons in Ireland","School of Chemical Sciences","Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland,Dublin 2,Ireland","School of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Medical Physics","institution_ids":[]},{"raw_affiliation_string":"Dublin 2","institution_ids":[]},{"raw_affiliation_string":"Ireland","institution_ids":[]},{"raw_affiliation_string":"Royal College of Surgeons in Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"School of Chemical Sciences","institution_ids":[]},{"raw_affiliation_string":"Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland,Dublin 2,Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"School of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland","institution_ids":["https://openalex.org/I42934936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043113948","display_name":"Eva Maria Jimenez-Mateos","orcid":"https://orcid.org/0000-0001-6417-6580","observed_orcids":["https://orcid.org/0000-0001-6417-6580"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Eva M. Jimenez-Mateos","raw_affiliation_strings":["Department of Physiology and Medical Physics","Dublin 2","Ireland","Royal College of Surgeons in Ireland","Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Medical Physics","institution_ids":[]},{"raw_affiliation_string":"Dublin 2","institution_ids":[]},{"raw_affiliation_string":"Ireland","institution_ids":[]},{"raw_affiliation_string":"Royal College of Surgeons in Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, 2, Ireland","institution_ids":["https://openalex.org/I142762351"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038393600","display_name":"Rana M.  Raoof","orcid":"https://orcid.org/0000-0001-5418-1407","observed_orcids":["https://orcid.org/0000-0001-5418-1407"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Rana Raoof","raw_affiliation_strings":["Department of Physiology and Medical Physics","Dublin 2","Ireland","Royal College of Surgeons in Ireland","Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Medical Physics","institution_ids":[]},{"raw_affiliation_string":"Dublin 2","institution_ids":[]},{"raw_affiliation_string":"Ireland","institution_ids":[]},{"raw_affiliation_string":"Royal College of Surgeons in Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, 2, Ireland","institution_ids":["https://openalex.org/I142762351"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018906146","display_name":"Hany El Naggar","orcid":"https://orcid.org/0000-0001-6500-5273","observed_orcids":["https://orcid.org/0000-0001-6500-5273"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]},{"id":"https://openalex.org/I2801846703","display_name":"Beaumont Hospital","ror":"https://ror.org/043mzjj67","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2801846703"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Hani ElNaggar","raw_affiliation_strings":["Department of Physiology and Medical Physics","Dublin 2","Ireland","Neurological Services","Royal College of Surgeons in Ireland","Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland,Dublin 2,Ireland","Neurological Services, Beaumont Hospital,Dublin 9,Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Medical Physics","institution_ids":[]},{"raw_affiliation_string":"Dublin 2","institution_ids":[]},{"raw_affiliation_string":"Ireland","institution_ids":[]},{"raw_affiliation_string":"Neurological Services","institution_ids":[]},{"raw_affiliation_string":"Royal College of Surgeons in Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland,Dublin 2,Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Neurological Services, Beaumont Hospital,Dublin 9,Ireland","institution_ids":["https://openalex.org/I2801846703"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113564480","display_name":"Norman Delanty","orcid":"https://orcid.org/0000-0002-3953-9842","observed_orcids":["https://orcid.org/0000-0002-3953-9842"]},"institutions":[{"id":"https://openalex.org/I2801846703","display_name":"Beaumont Hospital","ror":"https://ror.org/043mzjj67","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2801846703"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Norman Delanty","raw_affiliation_strings":["Beaumont Hospital","Dublin 9","Ireland","Neurological Services","Neurological Services, Beaumont Hospital, Dublin 9, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beaumont Hospital","institution_ids":["https://openalex.org/I2801846703"]},{"raw_affiliation_string":"Dublin 9","institution_ids":[]},{"raw_affiliation_string":"Ireland","institution_ids":[]},{"raw_affiliation_string":"Neurological Services","institution_ids":[]},{"raw_affiliation_string":"Neurological Services, Beaumont Hospital, Dublin 9, Ireland","institution_ids":["https://openalex.org/I2801846703"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005800766","display_name":"Robert J. Forster","orcid":"https://orcid.org/0000-0001-5079-3123","observed_orcids":["https://orcid.org/0000-0001-5079-3123"]},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Robert J. Forster","raw_affiliation_strings":["Dublin 9","Dublin City University","Ireland","National Centre for Sensor Research","School of Chemical Sciences","School of Chemical Sciences, National Centre for Sensor Research Dublin City University Dublin 9 Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dublin 9","institution_ids":[]},{"raw_affiliation_string":"Dublin City University","institution_ids":["https://openalex.org/I42934936"]},{"raw_affiliation_string":"Ireland","institution_ids":[]},{"raw_affiliation_string":"National Centre for Sensor Research","institution_ids":[]},{"raw_affiliation_string":"School of Chemical Sciences","institution_ids":[]},{"raw_affiliation_string":"School of Chemical Sciences, National Centre for Sensor Research Dublin City University Dublin 9 Ireland","institution_ids":["https://openalex.org/I42934936"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002978004","display_name":"David Clifford Henshall","orcid":"https://orcid.org/0000-0001-6237-9632","observed_orcids":["https://orcid.org/0000-0001-6237-9632"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"David C. Henshall","raw_affiliation_strings":["Department of Physiology and Medical Physics","Dublin 2","Ireland","Royal College of Surgeons in Ireland","Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Medical Physics","institution_ids":[]},{"raw_affiliation_string":"Dublin 2","institution_ids":[]},{"raw_affiliation_string":"Ireland","institution_ids":[]},{"raw_affiliation_string":"Royal College of Surgeons in Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, 2, Ireland","institution_ids":["https://openalex.org/I142762351"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5002978004","https://openalex.org/A5005800766","https://openalex.org/A5084137874"],"corresponding_institution_ids":["https://openalex.org/I142762351","https://openalex.org/I42934936"],"apc_list":{"value":850,"currency":"GBP","value_usd":1042},"apc_paid":null,"fwci":0.9435,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.71500473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"5","issue":"109","first_page":"90071","last_page":"90078"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna-134","display_name":"microRNA-134","score":0.9990000128746033},{"id":"https://openalex.org/keywords/electrochemical-detection","display_name":"electrochemical detection","score":0.800000011920929},{"id":"https://openalex.org/keywords/plasma-mirna","display_name":"plasma microRNA","score":0.878000020980835},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.9330000281333923},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.5929999947547913}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.8165438771247864},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.6870969533920288},{"id":"https://openalex.org/C59759590","wikidata":"https://www.wikidata.org/wiki/Q2275927","display_name":"Regioselectivity","level":3,"score":0.5469607710838318},{"id":"https://openalex.org/C3020134792","wikidata":"https://www.wikidata.org/wiki/Q79749","display_name":"Human plasma","level":2,"score":0.5189773440361023},{"id":"https://openalex.org/C82706917","wikidata":"https://www.wikidata.org/wiki/Q10251","display_name":"Plasma","level":2,"score":0.5069296956062317},{"id":"https://openalex.org/C77077793","wikidata":"https://www.wikidata.org/wiki/Q336019","display_name":"Abundance (ecology)","level":2,"score":0.4824979305267334},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.4213974177837372},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37874671816825867},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2194957733154297},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1838732361793518},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16941621899604797},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15388983488082886},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.11805352568626404},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.11589062213897705},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0712164044380188},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/c5ra16352h","doi":"https://doi.org/10.1039/c5ra16352h","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c5ra16352h","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5484666432","display_name":null,"funder_award_id":"GOIPD/2014/416","funder_id":"https://openalex.org/F4320321056","funder_display_name":"Irish Research Council"},{"id":"https://openalex.org/G6078367871","display_name":null,"funder_award_id":"10/IN.1/B3121, 13/IA/1891 and 13/SIRG/2114","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"}],"funders":[{"id":"https://openalex.org/F4320320847","display_name":"Science Foundation Ireland","ror":"https://ror.org/0271asj38"},{"id":"https://openalex.org/F4320321056","display_name":"Irish Research Council","ror":"https://ror.org/051xex213"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1971778349","https://openalex.org/W1974540586","https://openalex.org/W1978437325","https://openalex.org/W1996915289","https://openalex.org/W2001173515","https://openalex.org/W2008662133","https://openalex.org/W2030070077","https://openalex.org/W2032954363","https://openalex.org/W2043599468","https://openalex.org/W2048453642","https://openalex.org/W2049944045","https://openalex.org/W2052985891","https://openalex.org/W2060481603","https://openalex.org/W2062993238","https://openalex.org/W2074480115","https://openalex.org/W2078812502","https://openalex.org/W2105153983","https://openalex.org/W2107139283","https://openalex.org/W2115093090","https://openalex.org/W2132997088","https://openalex.org/W2135624681","https://openalex.org/W2138473891","https://openalex.org/W2140220489","https://openalex.org/W2161222316","https://openalex.org/W2163106706","https://openalex.org/W2259537051","https://openalex.org/W2312464259","https://openalex.org/W2318944718","https://openalex.org/W2322786785","https://openalex.org/W2325068077","https://openalex.org/W2333836441","https://openalex.org/W4232918452"],"related_works":["https://openalex.org/W2611182469","https://openalex.org/W3112181858","https://openalex.org/W2011165111","https://openalex.org/W2896145071","https://openalex.org/W2193228473","https://openalex.org/W2018954730","https://openalex.org/W2779578952","https://openalex.org/W4315652706","https://openalex.org/W2957511034","https://openalex.org/W2038044288"],"abstract_inverted_index":{"We":[0],"report":[1],"a":[2,8],"novel":[3],"electrochemical":[4],"detection":[5],"of":[6],"microRNA-134,":[7],"low-abundance":[9],"human":[10],"plasma":[11],"microRNA,":[12],"based":[13],"on":[14],"regioselective":[15],"functionalised":[16],"electrocatalytic":[17],"nanoparticles.":[18]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}
