{"id":"https://openalex.org/W1834529319","doi":"https://doi.org/10.1002/14651858.cd006569.pub5","title":"Aripiprazole versus other atypical antipsychotics for schizophrenia","display_name":"Aripiprazole versus other atypical antipsychotics for schizophrenia","publication_year":2014,"publication_date":"2014-01-02","ids":{"openalex":"https://openalex.org/W1834529319","doi":"https://doi.org/10.1002/14651858.cd006569.pub5","mag":"1834529319","pmid":"https://pubmed.ncbi.nlm.nih.gov/24385408","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6473905"},"language":"en","primary_location":{"id":"doi:10.1002/14651858.cd006569.pub5","doi":"https://doi.org/10.1002/14651858.cd006569.pub5","is_oa":false,"landing_page_url":"https://doi.org/10.1002/14651858.cd006569.pub5","pdf_url":null,"source":{"id":"https://openalex.org/S4210172715","display_name":"Cochrane Database of Systematic Reviews","issn_l":"1361-6137","issn":["1361-6137","1464-780X","1465-184X","1465-1858","1469-493X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","jufo-2","ki-jl-2","medline","norway-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cochrane Database of Systematic Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6473905","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025667381","display_name":"Priya Khanna","orcid":"https://orcid.org/0000-0002-8441-2322","observed_orcids":["https://orcid.org/0000-0002-8441-2322"]},"institutions":[{"id":"https://openalex.org/I240202130","display_name":"Cumbria Northumberland Tyne and Wear NHS Foundation Trust","ror":"https://ror.org/01ajv0n48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I240202130"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Priya Khanna","raw_affiliation_strings":["Northumberland, Tyne and Wear NHS Foundation Trust; Rehabilitation and Recovery, Adult Psychiatry; Newcastle UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northumberland, Tyne and Wear NHS Foundation Trust; Rehabilitation and Recovery, Adult Psychiatry; Newcastle UK","institution_ids":["https://openalex.org/I240202130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102848266","display_name":"Tao Suo","orcid":"https://orcid.org/0000-0002-4146-8123","observed_orcids":["https://orcid.org/0000-0002-4146-8123"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tao Suo","raw_affiliation_strings":["Zhongshan Hospital, Fudan University; Department of General Surgery, Institute of General Surgery; 180 Fenglin Road, Xuhui District Shanghai Shanghai China 200032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhongshan Hospital, Fudan University; Department of General Surgery, Institute of General Surgery; 180 Fenglin Road, Xuhui District Shanghai Shanghai China 200032","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046445175","display_name":"Katja Komossa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Katja Komossa","raw_affiliation_strings":["University Hospital of Zurich; Department of Psychiatry and Psychotherapy; Culmannstrasse 8 Zurich Switzerland CH-8091"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital of Zurich; Department of Psychiatry and Psychotherapy; Culmannstrasse 8 Zurich Switzerland CH-8091","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046384870","display_name":"Huaixing Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huaixing Ma","raw_affiliation_strings":["Zhongshan Hospital, Fudan University; Department of Medical Oncology; Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhongshan Hospital, Fudan University; Department of Medical Oncology; Shanghai China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016537819","display_name":"Christine Rummel\u2010Kluge","orcid":"https://orcid.org/0000-0003-4857-8170","observed_orcids":["https://orcid.org/0000-0003-4857-8170"]},"institutions":[{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christine Rummel-Kluge","raw_affiliation_strings":["University of Leipzig; Clinic and Outpatient Clinic of Psychiatry and Psychotherapy; Semmelweisstrasse 10 Leipzig Saxony Germany 04103"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Leipzig; Clinic and Outpatient Clinic of Psychiatry and Psychotherapy; Semmelweisstrasse 10 Leipzig Saxony Germany 04103","institution_ids":["https://openalex.org/I926574661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089457387","display_name":"Hany George G El-Sayeh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133429","display_name":"Harrogate District Hospital","ror":"https://ror.org/03044am22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802598605","https://openalex.org/I4210133429"]},{"id":"https://openalex.org/I4210158787","display_name":"Tees, Esk and Wear Valleys NHS Foundation Trust","ror":"https://ror.org/04s03zf45","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210158787"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hany G El-Sayeh","raw_affiliation_strings":["Tees, Esk & Wear Valleys NHS Foundation Trust; Harrogate District Hospital; Briary Wing Lancaster Park Road Harrogate North Yorkshire UK HG2 7SX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tees, Esk & Wear Valleys NHS Foundation Trust; Harrogate District Hospital; Briary Wing Lancaster Park Road Harrogate North Yorkshire UK HG2 7SX","institution_ids":["https://openalex.org/I4210133429","https://openalex.org/I4210158787"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002251483","display_name":"Stefan Leucht","orcid":"https://orcid.org/0000-0002-4934-4352","observed_orcids":["https://orcid.org/0000-0002-4934-4352"]},"institutions":[{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I4210147185","display_name":"Klinik und Poliklinik f\u00fcr Psychiatrie und Psychotherapie","ror":"https://ror.org/03j546b66","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4210147185","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Leucht","raw_affiliation_strings":["Technische Universit\u00e4t M\u00fcnchen Klinikum rechts der Isar; Klinik und Poliklinik f\u00fcr Psychiatrie und Psychotherapie; Ismaninger Stra\u00dfe 22 M\u00fcnchen Germany 81675"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t M\u00fcnchen Klinikum rechts der Isar; Klinik und Poliklinik f\u00fcr Psychiatrie und Psychotherapie; Ismaninger Stra\u00dfe 22 M\u00fcnchen Germany 81675","institution_ids":["https://openalex.org/I2802619606","https://openalex.org/I4210147185","https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069771666","display_name":"Jun Xia","orcid":"https://orcid.org/0000-0002-6823-4757","observed_orcids":["https://orcid.org/0000-0002-6823-4757"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]},{"id":"https://openalex.org/I4210101111","display_name":"Institute of Mental Health","ror":"https://ror.org/015dvxx67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210101111"]},{"id":"https://openalex.org/I4210161245","display_name":"Cochrane Canada","ror":"https://ror.org/05cf80b72","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210161245","https://openalex.org/I72054575"]},{"id":"https://openalex.org/I72054575","display_name":"Cochrane","ror":"https://ror.org/00dbkrq51","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I72054575"]}],"countries":["CA","GB"],"is_corresponding":false,"raw_author_name":"Jun Xia","raw_affiliation_strings":["The University of Nottingham; Cochrane Schizophrenia Group; Institute of Mental Health University of Nottingham Innovation Park, Triumph Road, Nottingham UK NG7 2TU"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Nottingham; Cochrane Schizophrenia Group; Institute of Mental Health University of Nottingham Innovation Park, Triumph Road, Nottingham UK NG7 2TU","institution_ids":["https://openalex.org/I142263535","https://openalex.org/I4210101111","https://openalex.org/I4210161245","https://openalex.org/I72054575"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":15,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5100,"currency":"USD","value_usd":5100},"apc_paid":null,"fwci":2.2283,"has_fulltext":false,"cited_by_count":155,"citation_normalized_percentile":{"value":0.90985325,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"2016","issue":"10","first_page":"CD006569","last_page":"CD006569"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aripiprazole","display_name":"aripiprazole","score":0.9990000128746033},{"id":"https://openalex.org/keywords/atypical-antipsychotics","display_name":"atypical antipsychotics","score":0.9449999928474426},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.953000009059906},{"id":"https://openalex.org/keywords/schizophrenia-like-psychoses","display_name":"schizophrenia-like psychoses","score":0.828000009059906},{"id":"https://openalex.org/keywords/clozapine","display_name":"clozapine","score":0.8180000185966492},{"id":"https://openalex.org/keywords/quetiapine","display_name":"quetiapine","score":0.8859999775886536},{"id":"https://openalex.org/keywords/risperidone","display_name":"risperidone","score":0.9810000061988831},{"id":"https://openalex.org/keywords/olanzapine","display_name":"olanzapine","score":0.8949999809265137},{"id":"https://openalex.org/keywords/ziprasidone","display_name":"ziprasidone","score":0.9700000286102295},{"id":"https://openalex.org/keywords/amisulpride","display_name":"amisulpride","score":0.9269999861717224},{"id":"https://openalex.org/keywords/sertindole","display_name":"sertindole","score":0.8849999904632568},{"id":"https://openalex.org/keywords/zotepine","display_name":"zotepine","score":0.9589999914169312},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.5249999761581421},{"id":"https://openalex.org/keywords/tolerability","display_name":"tolerability","score":0.9649999737739563},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.753000020980835},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.41200000047683716},{"id":"https://openalex.org/keywords/antipsychotic-comparison","display_name":"antipsychotic comparison","score":0.4650000035762787}],"concepts":[{"id":"https://openalex.org/C2777270317","wikidata":"https://www.wikidata.org/wiki/Q205517","display_name":"Ziprasidone","level":4,"score":0.917489767074585},{"id":"https://openalex.org/C2780211496","wikidata":"https://www.wikidata.org/wiki/Q411188","display_name":"Aripiprazole","level":3,"score":0.9088829159736633},{"id":"https://openalex.org/C2780634440","wikidata":"https://www.wikidata.org/wiki/Q408535","display_name":"Quetiapine","level":3,"score":0.885765790939331},{"id":"https://openalex.org/C2776619155","wikidata":"https://www.wikidata.org/wiki/Q201872","display_name":"Olanzapine","level":3,"score":0.8786804676055908},{"id":"https://openalex.org/C2778999636","wikidata":"https://www.wikidata.org/wiki/Q418785","display_name":"Amisulpride","level":4,"score":0.8055683970451355},{"id":"https://openalex.org/C2780057945","wikidata":"https://www.wikidata.org/wiki/Q412443","display_name":"Risperidone","level":3,"score":0.7757030725479126},{"id":"https://openalex.org/C2780864610","wikidata":"https://www.wikidata.org/wiki/Q221361","display_name":"Clozapine","level":3,"score":0.6609798073768616},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6026579737663269},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5688548684120178},{"id":"https://openalex.org/C2780777758","wikidata":"https://www.wikidata.org/wiki/Q418050","display_name":"Sertindole","level":4,"score":0.5128586292266846},{"id":"https://openalex.org/C2776921671","wikidata":"https://www.wikidata.org/wiki/Q758295","display_name":"Atypical antipsychotic","level":4,"score":0.47773998975753784},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.47003573179244995},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.44742658734321594},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.33001095056533813}],"mesh":[{"descriptor_ui":"D000068180","descriptor_name":"Aripiprazole","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001569","descriptor_name":"Benzodiazepines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1002/14651858.cd006569.pub5","doi":"https://doi.org/10.1002/14651858.cd006569.pub5","is_oa":false,"landing_page_url":"https://doi.org/10.1002/14651858.cd006569.pub5","pdf_url":null,"source":{"id":"https://openalex.org/S4210172715","display_name":"Cochrane Database of Systematic Reviews","issn_l":"1361-6137","issn":["1361-6137","1464-780X","1465-184X","1465-1858","1469-493X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","jufo-2","ki-jl-2","medline","norway-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cochrane Database of Systematic Reviews","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5457061","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6473905","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6473905","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6473905","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cochrane Database Syst Rev","raw_type":"Text"},{"id":"pmid:24385408","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24385408","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Cochrane database of systematic reviews","raw_type":"Journal Article"},{"id":"pmh:oai:www.zora.uzh.ch:104554","doi":null,"is_oa":false,"landing_page_url":"https://www.zora.uzh.ch/104554","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Khanna, Priya; Suo, Tao; Komossa, Katja; Ma, Huaixing; Rummel-Kluge, Christine; El-Sayeh, Hany George; Leucht, Stefan; Xia, Jun (2014). Aripiprazole versus other atypical antipsychotics for schizophrenia. Cochrane Database of Systematic Reviews, 1:online.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:mediatum.ub.tum.de:node/1252014","doi":null,"is_oa":false,"landing_page_url":"https://mediatum.ub.tum.de/1252014","pdf_url":null,"source":{"id":"https://openalex.org/S4306400453","display_name":"mediaTUM \u2013 the media and publications repository of the Technical University Munich (Technical University Munich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I62916508","host_organization_name":"Technical University of Munich","host_organization_lineage":["https://openalex.org/I62916508"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:www.zora.uzh.ch:20.500.14742/83074","doi":null,"is_oa":false,"landing_page_url":"https://www.zora.uzh.ch/handle/20.500.14742/83074","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Khanna, P., Suo, T., Komossa, K., Ma, H., Rummel-Kluge, C., El-Sayeh, H. G., Leucht, S., & Xia, J. (2014). Aripiprazole versus other atypical antipsychotics for schizophrenia. Cochrane Database of Systematic Reviews, 1, online. https://doi.org/10.1002/14651858.CD006569.pub5","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5457061","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6473905","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[{"id":"https://openalex.org/G6935256489","display_name":null,"funder_award_id":"10/4001/15","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":214,"referenced_works":["https://openalex.org/W200959462","https://openalex.org/W945298733","https://openalex.org/W1197406485","https://openalex.org/W1514885645","https://openalex.org/W1538786326","https://openalex.org/W1562262302","https://openalex.org/W1591259115","https://openalex.org/W1598577731","https://openalex.org/W1710169825","https://openalex.org/W1740467237","https://openalex.org/W1801862032","https://openalex.org/W1898504652","https://openalex.org/W1904924604","https://openalex.org/W1911611356","https://openalex.org/W1919383023","https://openalex.org/W1929424476","https://openalex.org/W1930770730","https://openalex.org/W1933606243","https://openalex.org/W1964162160","https://openalex.org/W1965400785","https://openalex.org/W1969303234","https://openalex.org/W1969594906","https://openalex.org/W1970358906","https://openalex.org/W1972445824","https://openalex.org/W1977185679","https://openalex.org/W1978040764","https://openalex.org/W1984360293","https://openalex.org/W1986076510","https://openalex.org/W1989227490","https://openalex.org/W1990123262","https://openalex.org/W1992857340","https://openalex.org/W1994539827","https://openalex.org/W1996205985","https://openalex.org/W1997785005","https://openalex.org/W1998036667","https://openalex.org/W1998500865","https://openalex.org/W1999689270","https://openalex.org/W2008704671","https://openalex.org/W2009352904","https://openalex.org/W2009577021","https://openalex.org/W2011157927","https://openalex.org/W2020844317","https://openalex.org/W2023839473","https://openalex.org/W2026577398","https://openalex.org/W2028060030","https://openalex.org/W2029103055","https://openalex.org/W2030649010","https://openalex.org/W2031708902","https://openalex.org/W2032712358","https://openalex.org/W2033607889","https://openalex.org/W2037152049","https://openalex.org/W2037545297","https://openalex.org/W2037986092","https://openalex.org/W2040674586","https://openalex.org/W2049842299","https://openalex.org/W2051256844","https://openalex.org/W2056706753","https://openalex.org/W2058874144","https://openalex.org/W2059131243","https://openalex.org/W2059208906","https://openalex.org/W2060147694","https://openalex.org/W2060694936","https://openalex.org/W2064125890","https://openalex.org/W2065001844","https://openalex.org/W2070728590","https://openalex.org/W2075153233","https://openalex.org/W2075364782","https://openalex.org/W2075884901","https://openalex.org/W2076273987","https://openalex.org/W2079153272","https://openalex.org/W2081225070","https://openalex.org/W2082218913","https://openalex.org/W2083252023","https://openalex.org/W2085360366","https://openalex.org/W2086996694","https://openalex.org/W2089642450","https://openalex.org/W2091051097","https://openalex.org/W2094503896","https://openalex.org/W2095927831","https://openalex.org/W2106419137","https://openalex.org/W2109196233","https://openalex.org/W2109422448","https://openalex.org/W2114801996","https://openalex.org/W2115058221","https://openalex.org/W2125435699","https://openalex.org/W2127313266","https://openalex.org/W2128659393","https://openalex.org/W2130235475","https://openalex.org/W2133743804","https://openalex.org/W2135029321","https://openalex.org/W2143962486","https://openalex.org/W2147668060","https://openalex.org/W2149639459","https://openalex.org/W2152240392","https://openalex.org/W2156690391","https://openalex.org/W2157007129","https://openalex.org/W2157345039","https://openalex.org/W2157823046","https://openalex.org/W2159155203","https://openalex.org/W2160385738","https://openalex.org/W2160409159","https://openalex.org/W2161394544","https://openalex.org/W2164182651","https://openalex.org/W2165379748","https://openalex.org/W2170572319","https://openalex.org/W2172047405","https://openalex.org/W2291961189","https://openalex.org/W2348693174","https://openalex.org/W2349463470","https://openalex.org/W2349890034","https://openalex.org/W2350312188","https://openalex.org/W2350437057","https://openalex.org/W2350652787","https://openalex.org/W2350700761","https://openalex.org/W2351938186","https://openalex.org/W2352722056","https://openalex.org/W2353350277","https://openalex.org/W2354259060","https://openalex.org/W2355036463","https://openalex.org/W2355723850","https://openalex.org/W2356027170","https://openalex.org/W2356456125","https://openalex.org/W2356579256","https://openalex.org/W2358017376","https://openalex.org/W2358253064","https://openalex.org/W2358480191","https://openalex.org/W2358501463","https://openalex.org/W2358564596","https://openalex.org/W2359828196","https://openalex.org/W2360192066","https://openalex.org/W2360616940","https://openalex.org/W2361194172","https://openalex.org/W2361482857","https://openalex.org/W2361836069","https://openalex.org/W2362013557","https://openalex.org/W2363455841","https://openalex.org/W2363886953","https://openalex.org/W2364065084","https://openalex.org/W2364534831","https://openalex.org/W2365038886","https://openalex.org/W2365098272","https://openalex.org/W2365222557","https://openalex.org/W2365555698","https://openalex.org/W2365572581","https://openalex.org/W2367115031","https://openalex.org/W2367576060","https://openalex.org/W2368152300","https://openalex.org/W2368410623","https://openalex.org/W2368790838","https://openalex.org/W2369926972","https://openalex.org/W2370041720","https://openalex.org/W2370708291","https://openalex.org/W2370903671","https://openalex.org/W2370989125","https://openalex.org/W2371254519","https://openalex.org/W2372009398","https://openalex.org/W2372367222","https://openalex.org/W2372416518","https://openalex.org/W2372529584","https://openalex.org/W2373268711","https://openalex.org/W2373444204","https://openalex.org/W2373655898","https://openalex.org/W2375577460","https://openalex.org/W2375608525","https://openalex.org/W2375835751","https://openalex.org/W2375864840","https://openalex.org/W2376333860","https://openalex.org/W2376912687","https://openalex.org/W2376952458","https://openalex.org/W2377328056","https://openalex.org/W2378433253","https://openalex.org/W2378725359","https://openalex.org/W2379037399","https://openalex.org/W2380079590","https://openalex.org/W2380789243","https://openalex.org/W2381401217","https://openalex.org/W2381901374","https://openalex.org/W2383098626","https://openalex.org/W2384435789","https://openalex.org/W2385256580","https://openalex.org/W2385609905","https://openalex.org/W2386829842","https://openalex.org/W2387459826","https://openalex.org/W2388097494","https://openalex.org/W2388467458","https://openalex.org/W2388498104","https://openalex.org/W2389044417","https://openalex.org/W2389069439","https://openalex.org/W2390291106","https://openalex.org/W2390698915","https://openalex.org/W2391595643","https://openalex.org/W2391622241","https://openalex.org/W2391989814","https://openalex.org/W2392259366","https://openalex.org/W2392398171","https://openalex.org/W2394666283","https://openalex.org/W2412252531","https://openalex.org/W2516970163","https://openalex.org/W2607257274","https://openalex.org/W3030185414","https://openalex.org/W3030286894","https://openalex.org/W3090293687","https://openalex.org/W4205195518","https://openalex.org/W4230406515","https://openalex.org/W4234005700","https://openalex.org/W4237049133","https://openalex.org/W4243394892","https://openalex.org/W4246353915","https://openalex.org/W4253062103","https://openalex.org/W4285719527","https://openalex.org/W4320288061","https://openalex.org/W6653264683","https://openalex.org/W6726748224","https://openalex.org/W7065453697"],"related_works":["https://openalex.org/W2082854222","https://openalex.org/W2058181488","https://openalex.org/W2160385738","https://openalex.org/W2156690391","https://openalex.org/W1937116112","https://openalex.org/W1740467237","https://openalex.org/W2147522149","https://openalex.org/W2115776100","https://openalex.org/W4254864136","https://openalex.org/W7117298604"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1,20],"most":[2],"western":[3],"industrialised":[4],"countries,":[5],"second":[6,44],"generation":[7,45],"(atypical)":[8],"antipsychotics":[9,58],"are":[10,801],"recommended":[11],"as":[12,814],"first-line":[13],"drug":[14,92,792],"treatments":[15],"for":[16,59,84,99,129,174,196,256,288,361,390,422,460,476,495,564,595,650,751,808],"people":[17,60,130,613,695,723],"with":[18,55,61,114,131,223,249,354,453,518,557,643,793],"schizophrenia.":[19],"this":[21,812],"review,":[22],"we":[23,147,169,180],"specifically":[24],"examine":[25],"how":[26],"the":[27,50,70,285,305,387,473,501,579,592,680,699,745,752,780],"efficacy":[28],"and":[29,63,87,95,116,152,200,228,720,772,803],"tolerability":[30],"of":[31,41,52,80,97,119,194,207,233,301,420,424,493,527,551,637,677,691,744,754,767,779,811],"one":[32],"such":[33],"agent":[34],"-":[35,37],"aripiprazole":[36,53,112,312,421,494,615,697],"differs":[38],"from":[39,818],"that":[40],"other":[42,56],"comparable":[43],"antipsychotics.":[46],"OBJECTIVES:":[47],"To":[48],"review":[49,813],"effects":[51,521],"compared":[54,222,248,353,452,556,642],"atypical":[57],"schizophrenia":[62,132],"schizophrenia-like":[64,134],"psychoses.":[65,135],"SEARCH":[66],"METHODS:":[67],"We":[68,104,140,191,211],"searched":[69],"Cochrane":[71],"Schizophrenia":[72],"Group":[73],"Trials":[74],"Register":[75],"(November":[76],"2012),":[77],"inspected":[78],"references":[79],"all":[81,106,764,783],"identified":[82],"studies":[83,236,747],"further":[85],"trials":[86,98,109,216],"contacted":[88],"relevant":[89],"pharmaceutical":[90],"companies,":[91],"approval":[93],"agencies":[94],"authors":[96],"additional":[100],"information.":[101],"SELECTION":[102],"CRITERIA:":[103],"included":[105,198,214,746],"randomised":[107],"clinical":[108],"(RCTs)":[110],"comparing":[111],"(oral)":[113],"oral":[115],"parenteral":[117],"forms":[118],"amisulpride,":[120],"clozapine,":[121,224,250],"olanzapine,":[122,644],"quetiapine,":[123,225,355],"risperidone,":[124,226,454],"sertindole,":[125],"ziprasidone":[126,227],"or":[127,133,283,350,402,449,471,553,590,639,675,757,785],"zotepine":[128],"DATA":[136],"COLLECTION":[137],"AND":[138],"ANALYSIS:":[139],"extracted":[141],"data":[142,146,750,800,816],"independently.":[143],"For":[144,177],"dichotomous":[145],"calculated":[148,170,181],"risk":[149,193],"ratios":[150],"(RR)":[151],"their":[153],"95%":[154],"confidence":[155],"intervals":[156],"(CI)":[157],"on":[158,163,187,763],"an":[159,790,794],"intention-to-treat":[160],"basis":[161],"based":[162,186],"a":[164,188],"random-effects":[165,189],"model.":[166,190],"Where":[167],"possible,":[168],"illustrative":[171],"comparative":[172],"risks":[173],"primary":[175],"outcomes.":[176],"continuous":[178],"data,":[179],"mean":[182],"differences":[183,245,255,360,459,563,649],"(MD),":[184],"again":[185],"assessed":[192],"bias":[195],"each":[197],"study":[199,286,346,388,445,474,546,593,632,700],"used":[201],"GRADE":[202],"approach":[203],"to":[204,240,322,438,512,540,625,703,715,737,774],"rate":[205],"quality":[206,269,281,298,326,343,370,384,400,413,423,442,469,486,516,543,550,574,588,605,629,636,660,673,676,690,718,741,778],"evidence.":[208],"MAIN":[209],"RESULTS:":[210],"now":[212],"have":[213],"174":[215],"involving":[217],"17,244":[218],"participants.":[219],"Aripiprazole":[220,788],"was":[221,238,609],"olanzapine.":[229],"The":[230,777],"overall":[231],"number":[232],"participants":[234,524],"leaving":[235,284,386,472,591],"early":[237,287,389,475,594,701],"30%":[239],"40%,":[241],"limiting":[242],"validity":[243],"(no":[244,259],"between":[246,335],"groups).When":[247],"there":[251,356,455,559,645,804],"were":[252,332,357,416,456,489,560,646],"no":[253,333,358,457,561,647],"significant":[254,261,309,359,458,562,648],"global":[257,362,461,565,651],"state":[258,272,363,373,462,499,566,577,652,663],"clinically":[260],"response,":[262],"n":[263,274,377,429],"=":[264,275,292,314,338,365,378,394,407,430,464,480,504,532,568,582,599,617,654,667,684,707,729],"2132,":[265],"29":[266],"RCTs,":[267,278,295,317,368,381,397,410,467,483,507,535,571,602,620,657,670,710,732],"low":[268,280,297,325,342,369,383,399,412,441,468,485,515,542,573,587,604,628,659,672,689,717,740,784],"evidence);":[270,282,371,385,470,517,575,589,661,674],"mental":[271,372,498,576,662],"(BPRS,":[273],"426,":[276],"5":[277,506],"very":[279,296,324,382,398,411,440,484,514,572,586,603,627,658,671,688,739,786],"any":[289,391,477,596,704],"reason":[290,392,478,597,705],"(n":[291,313,337,364,393,406,463,479,503,531,567,581,598,616,653,666,683,706,728],"240,":[293],"3":[294,619],"evidence).":[299,327,344,414,443,487,544,606,630,692,742],"Quality":[300],"life":[302,425,552,638,678],"score":[303],"using":[304,500,578,664,679],"WHO-QOL-100":[306],"scale":[307,682],"demonstrated":[308],"difference,":[310],"favouring":[311],"132,":[315],"2":[316,396,601],"RR":[318,536,621,711,733],"2.59":[319],"CI":[320,436,510,538,623,713,735],"1.43":[321],"3.74,":[323],"General":[328],"extrapyramidal":[329],"symptoms":[330,405,530],"(EPS)":[331],"different":[334],"groups":[336],"520,":[339],"8":[340],"RCTs,very":[341],"No":[345,444,545,631],"reported":[347,446,547,633],"general":[348,403,447,528,548,634],"functioning":[349,448],"service":[351,450,554,640],"use.When":[352,451,555,641],"991,":[366],"12":[367,482],"(PANSS":[374],"positive":[375],"symptoms,":[376],"583,":[379],"7":[380],"168,":[395],"evidence),":[401],"EPS":[404,529],"348,":[408],"4":[409],"Results":[415],"significantly":[417,490,610,721],"in":[418,491,497,523,612],"favour":[419,492],"(WHO-QOL-100":[426],"total":[427],"score,":[428],"100,":[431],"1":[432,584,686],"RCT,":[433,585,687],"MD":[434,508],"2.60":[435],"1.31":[437],"3.89,":[439],"6381,":[465],"80":[466],"1239,":[481],"Data":[488],"improvement":[496],"BPRS":[502,580],"570,":[505],"1.33":[509],"2.24":[511],"0.42,":[513],"higher":[519],"adverse":[520,796],"seen":[522],"receiving":[525,614,696,724],"risperidone":[526],"2605,":[533],"31":[534],"0.39":[537],"0.31":[539],"0.50,":[541],"functioning,":[549,635],"ziprasidone,":[558],"442,":[569],"6":[570],"247,":[583],"316,":[600],"Weight":[607],"gain":[608],"greater":[611],"232,":[618],"4.01":[622],"1.10":[624],"14.60,":[626],"1739,":[655],"11":[656,669],"PANSS":[665],"1500,":[668],"GQOLI-74":[681],"68,":[685],"Significantly":[693],"more":[694,722],"left":[698],"due":[702],"2331,":[708],"9":[709,731],"1.15":[712],"1.05":[714],"1.25,":[716],"evidence)":[719],"olanzapine":[725],"gained":[726],"weight":[727],"1538,":[730],"0.25":[734],"0.15":[736],"0.43,":[738],"None":[743],"provided":[748],"outcome":[749],"comparisons":[753,765],"'service":[755],"use'":[756],"'general":[758],"functioning'.":[759],"AUTHORS'":[760],"CONCLUSIONS:":[761],"Information":[762],"is":[766,770,782,789,805],"limited":[768],"quality,":[769],"incomplete":[771],"problematic":[773],"apply":[775],"clinically.":[776],"evidence":[781],"low.":[787],"antipsychotic":[791],"important":[795],"effect":[797],"profile.":[798],"Long-term":[799],"sparse":[802],"considerable":[806],"scope":[807],"another":[809],"update":[810],"new":[815],"emerge":[817],"ongoing":[819],"larger,":[820],"independent":[821],"pragmatic":[822],"trials.":[823]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":20},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}