{"id":"https://openalex.org/W18338672","doi":"https://doi.org/10.1016/j.jmoldx.2013.07.002","title":"Laboratory Practice Guidelines for Detecting and Reporting JAK2 and MPL Mutations in Myeloproliferative Neoplasms","display_name":"Laboratory Practice Guidelines for Detecting and Reporting JAK2 and MPL Mutations in Myeloproliferative Neoplasms","publication_year":2013,"publication_date":"2013-08-24","ids":{"openalex":"https://openalex.org/W18338672","doi":"https://doi.org/10.1016/j.jmoldx.2013.07.002","mag":"18338672","pmid":"https://pubmed.ncbi.nlm.nih.gov/23978506"},"language":"en","primary_location":{"id":"doi:10.1016/j.jmoldx.2013.07.002","doi":"https://doi.org/10.1016/j.jmoldx.2013.07.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmoldx.2013.07.002","pdf_url":null,"source":{"id":"https://openalex.org/S48180145","display_name":"Journal of Molecular Diagnostics","issn_l":"1525-1578","issn":["1525-1578","1943-7811"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Molecular Diagnostics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.jmoldx.2013.07.002","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109335141","display_name":"Jerald Z. Gong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]},{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jerald Z. Gong","raw_affiliation_strings":["JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland; Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: Jerald.gong@jefferson.edu","Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland; Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: Jerald.gong@jefferson.edu","institution_ids":["https://openalex.org/I149251103","https://openalex.org/I4405257899"]},{"raw_affiliation_string":"Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania","institution_ids":["https://openalex.org/I149251103"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066731616","display_name":"James R. Cook","orcid":"https://orcid.org/0000-0003-0456-8085","observed_orcids":["https://orcid.org/0000-0003-0456-8085"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James R. Cook","raw_affiliation_strings":["Department of Clinical Pathology, Cleveland Clinic Foundation, Cleveland, Ohio","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pathology, Cleveland Clinic Foundation, Cleveland, Ohio","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046438171","display_name":"Timothy C. Greiner","orcid":"https://orcid.org/0000-0003-1470-8328","observed_orcids":["https://orcid.org/0000-0003-1470-8328"]},"institutions":[{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]},{"id":"https://openalex.org/I59130452","display_name":"University of Nebraska Medical Center","ror":"https://ror.org/00thqtb16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I59130452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy C. Greiner","raw_affiliation_strings":["Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska","institution_ids":["https://openalex.org/I59130452"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076224974","display_name":"Cyrus V. Hedvat","orcid":"https://orcid.org/0000-0003-0045-3491","observed_orcids":["https://orcid.org/0000-0003-0045-3491"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cyrus Hedvat","raw_affiliation_strings":["Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027270375","display_name":"Charles E. Hill","orcid":"https://orcid.org/0000-0002-8425-3296","observed_orcids":["https://orcid.org/0000-0002-8425-3296"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles E. Hill","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041898934","display_name":"Megan S. Lim","orcid":"https://orcid.org/0000-0002-0415-2867","observed_orcids":["https://orcid.org/0000-0002-0415-2867"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan S. Lim","raw_affiliation_strings":["Department of Pathology\u2013Hematopathology, University of Michigan, Ann Arbor, Michigan","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology\u2013Hematopathology, University of Michigan, Ann Arbor, Michigan","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071612414","display_name":"Janina A. Longtine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janina A. Longtine","raw_affiliation_strings":["Department of Pathology, Icahn School of Medicine at Mt. Sinai, New York, New York","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Icahn School of Medicine at Mt. Sinai, New York, New York","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077777322","display_name":"Daniel E. Sabath","orcid":"https://orcid.org/0000-0002-5322-0336","observed_orcids":["https://orcid.org/0000-0002-5322-0336"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Sabath","raw_affiliation_strings":["Department of Laboratory Medicine, University of Washington, Seattle, Washington","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062344658","display_name":"Y. Lynn Wang","orcid":"https://orcid.org/0000-0003-0773-1212","observed_orcids":["https://orcid.org/0000-0003-0773-1212"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405257899","display_name":"Association for Molecular Pathology","ror":"https://ror.org/05swbnm48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405257899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y. Lynn Wang","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York","JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland","institution_ids":["https://openalex.org/I4405257899"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5109335141"],"corresponding_institution_ids":["https://openalex.org/I149251103","https://openalex.org/I4405257899"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":2.4528,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.88368229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"15","issue":"6","first_page":"733","last_page":"744"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jak2-mutation","display_name":"JAK2 mutation","score":0.878000020980835},{"id":"https://openalex.org/keywords/mpl-mutation","display_name":"MPL mutation","score":1.0},{"id":"https://openalex.org/keywords/myeloproliferative-neoplasms","display_name":"myeloproliferative neoplasms","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bcr-abl1-negative-myeloproliferative-neoplasms","display_name":"BCR-ABL1-negative myeloproliferative neoplasms","score":0.9549999833106995},{"id":"https://openalex.org/keywords/mutation-detection","display_name":"mutation detection","score":0.7670000195503235},{"id":"https://openalex.org/keywords/genomic-testing","display_name":"genomic testing","score":0.4390000104904175}],"concepts":[{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4750418961048126},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38823267817497253},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3845940828323364},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.37157300114631653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3570173978805542},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32666462659835815},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.153328537940979}],"mesh":[{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025202","descriptor_name":"Molecular Diagnostic Techniques","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D025202","descriptor_name":"Molecular Diagnostic Techniques","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D025202","descriptor_name":"Molecular Diagnostic Techniques","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D053614","descriptor_name":"Janus Kinase 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053614","descriptor_name":"Janus Kinase 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053614","descriptor_name":"Janus Kinase 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053628","descriptor_name":"Receptors, Thrombopoietin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053628","descriptor_name":"Receptors, Thrombopoietin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053628","descriptor_name":"Receptors, Thrombopoietin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055088","descriptor_name":"Early Detection of Cancer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055088","descriptor_name":"Early Detection of Cancer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055088","descriptor_name":"Early Detection of Cancer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jmoldx.2013.07.002","doi":"https://doi.org/10.1016/j.jmoldx.2013.07.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmoldx.2013.07.002","pdf_url":null,"source":{"id":"https://openalex.org/S48180145","display_name":"Journal of Molecular Diagnostics","issn_l":"1525-1578","issn":["1525-1578","1943-7811"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Molecular Diagnostics","raw_type":"journal-article"},{"id":"pmid:23978506","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23978506","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of molecular diagnostics : JMD","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.jmoldx.2013.07.002","doi":"https://doi.org/10.1016/j.jmoldx.2013.07.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmoldx.2013.07.002","pdf_url":null,"source":{"id":"https://openalex.org/S48180145","display_name":"Journal of Molecular Diagnostics","issn_l":"1525-1578","issn":["1525-1578","1943-7811"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Molecular Diagnostics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":99,"referenced_works":["https://openalex.org/W161996477","https://openalex.org/W651165243","https://openalex.org/W1483308173","https://openalex.org/W1498640978","https://openalex.org/W1555806626","https://openalex.org/W1556994088","https://openalex.org/W1601865963","https://openalex.org/W1605230984","https://openalex.org/W1715726021","https://openalex.org/W1912678907","https://openalex.org/W1963736125","https://openalex.org/W1969140776","https://openalex.org/W1969611600","https://openalex.org/W1970390241","https://openalex.org/W1976479449","https://openalex.org/W1980568348","https://openalex.org/W1981484631","https://openalex.org/W1981965189","https://openalex.org/W1982158109","https://openalex.org/W1983494536","https://openalex.org/W1987362547","https://openalex.org/W1988019098","https://openalex.org/W1989188541","https://openalex.org/W1992197271","https://openalex.org/W1994580828","https://openalex.org/W1994790248","https://openalex.org/W1995653573","https://openalex.org/W1996778469","https://openalex.org/W1998271419","https://openalex.org/W1999608888","https://openalex.org/W2000173433","https://openalex.org/W2001457852","https://openalex.org/W2001492484","https://openalex.org/W2002763331","https://openalex.org/W2002968540","https://openalex.org/W2004841640","https://openalex.org/W2008198456","https://openalex.org/W2010596916","https://openalex.org/W2013726626","https://openalex.org/W2014919830","https://openalex.org/W2017410022","https://openalex.org/W2019264445","https://openalex.org/W2028390656","https://openalex.org/W2030493432","https://openalex.org/W2031969673","https://openalex.org/W2033646229","https://openalex.org/W2034379258","https://openalex.org/W2045411075","https://openalex.org/W2047375377","https://openalex.org/W2049145190","https://openalex.org/W2052451894","https://openalex.org/W2055915116","https://openalex.org/W2056344380","https://openalex.org/W2056777053","https://openalex.org/W2056903619","https://openalex.org/W2057360098","https://openalex.org/W2060988701","https://openalex.org/W2065160838","https://openalex.org/W2065161568","https://openalex.org/W2066465348","https://openalex.org/W2066509853","https://openalex.org/W2068898856","https://openalex.org/W2069943969","https://openalex.org/W2071140369","https://openalex.org/W2074300796","https://openalex.org/W2075970562","https://openalex.org/W2078391398","https://openalex.org/W2086377497","https://openalex.org/W2086549652","https://openalex.org/W2099264304","https://openalex.org/W2100840054","https://openalex.org/W2102462541","https://openalex.org/W2103452780","https://openalex.org/W2105496815","https://openalex.org/W2108771181","https://openalex.org/W2114713566","https://openalex.org/W2115418062","https://openalex.org/W2116878961","https://openalex.org/W2118601909","https://openalex.org/W2123633897","https://openalex.org/W2124119192","https://openalex.org/W2126665281","https://openalex.org/W2126894917","https://openalex.org/W2129398278","https://openalex.org/W2134513116","https://openalex.org/W2135367830","https://openalex.org/W2136903358","https://openalex.org/W2143039662","https://openalex.org/W2144664431","https://openalex.org/W2145590501","https://openalex.org/W2145968395","https://openalex.org/W2146505525","https://openalex.org/W2147717504","https://openalex.org/W2151968703","https://openalex.org/W2162619595","https://openalex.org/W2164427458","https://openalex.org/W2564846347","https://openalex.org/W4285719527","https://openalex.org/W4317527949"],"related_works":["https://openalex.org/W2319951181","https://openalex.org/W1715726021","https://openalex.org/W2257919076","https://openalex.org/W2551595682","https://openalex.org/W4389958609","https://openalex.org/W3137224022","https://openalex.org/W2363052932","https://openalex.org/W2761940868","https://openalex.org/W4362558385","https://openalex.org/W2990447257"],"abstract_inverted_index":{"Recurrent":[0],"mutations":[1,19,68],"in":[2,69,109],"JAK2":[3,16,41,71],"and":[4,17,42,52,60,72,84,91],"MPL":[5,18,43,73],"genes":[6],"are":[7],"genetic":[8],"hallmarks":[9],"of":[10,15,40,67],"BCR-ABL1-negative":[11,110],"myeloproliferative":[12,111],"neoplasms.":[13,112],"Detection":[14],"has":[20],"been":[21],"incorporated":[22],"into":[23],"routine":[24],"diagnostic":[25],"algorithms":[26],"for":[27,62,65,78,87,93,106],"these":[28],"diseases.":[29],"This":[30,98],"Special":[31,56,99],"Article":[32,57,100],"summarizes":[33],"results":[34],"from":[35],"a":[36],"nationwide":[37],"laboratory":[38,63],"survey":[39],"mutation":[44,81],"analysis.":[45],"Based":[46],"on":[47],"the":[48,53,70,80,89,95],"current":[49,83],"practice":[50,64],"pattern":[51],"literature,":[54],"this":[55],"provides":[58],"recommendations":[59],"guidelines":[61],"detection":[66],"genes,":[74],"including":[75],"clinical":[76],"manifestations":[77],"prompting":[79],"analysis,":[82],"recommended":[85],"methodologies":[86],"testing":[88,108],"mutations,":[90],"standardization":[92],"reporting":[94],"test":[96],"results.":[97],"also":[101],"points":[102],"to":[103],"future":[104],"directions":[105],"genomic":[107]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}