{"id":"https://openalex.org/W182780968","doi":null,"title":"Elevated PSA is associated with decreased physical function in men with prostate cancer","display_name":"Elevated PSA is associated with decreased physical function in men with prostate cancer","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W182780968","mag":"182780968"},"language":"en","primary_location":{"id":"pmh:oai:digitalcommons.wku.edu:ijesab-2278","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss7/35","pdf_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss7/35","source":{"id":"https://openalex.org/S4377196460","display_name":"TopSCHOLAR (Western Kentucky University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94339441","host_organization_name":"Western Kentucky University","host_organization_lineage":["https://openalex.org/I94339441"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Exercise Science: Conference Proceedings","raw_type":"text"},"volume":null,"type":"conference-paper","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss7/35","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017104457","display_name":"Clayton S Robinson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Clayton S Robinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5085773356","display_name":"Darpan I. Patel","orcid":"https://orcid.org/0000-0001-8124-8072","observed_orcids":["https://orcid.org/0000-0001-8124-8072"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Darpan I. Patel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8124-8072","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00186916,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"7","first_page":"35","last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.711899995803833,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.711899995803833,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.1574999988079071,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.02969999983906746,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9929999709129333},{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.8519999980926514},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.9139999747276306},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.7120000123977661},{"id":"https://openalex.org/keywords/fatigue","display_name":"fatigue","score":0.640999972820282},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.7590000033378601},{"id":"https://openalex.org/keywords/androgen-deprivation-therapy","display_name":"androgen deprivation therapy","score":0.9399999976158142},{"id":"https://openalex.org/keywords/salivary-cortisol","display_name":"salivary cortisol","score":0.8519999980926514},{"id":"https://openalex.org/keywords/cancer-related-fatigue","display_name":"cancer-related fatigue","score":0.6629999876022339},{"id":"https://openalex.org/keywords/emotional-problems","display_name":"emotional problems","score":0.5600000023841858},{"id":"https://openalex.org/keywords/physical-health","display_name":"physical health","score":0.5789999961853027},{"id":"https://openalex.org/keywords/metastatic-prostate-cancer","display_name":"metastatic prostate cancer","score":0.6840000152587891},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.9440000057220459},{"id":"https://openalex.org/keywords/prostatic-intraepithelial-neoplasia","display_name":"prostatic intraepithelial neoplasia","score":0.9240000247955322},{"id":"https://openalex.org/keywords/localized-prostate-cancer","display_name":"localized prostate cancer","score":0.8539999723434448},{"id":"https://openalex.org/keywords/brief-fatigue-inventory","display_name":"Brief Fatigue Inventory","score":0.699999988079071},{"id":"https://openalex.org/keywords/sf-36","display_name":"SF-36","score":0.9169999957084656}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7888997197151184},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5835996866226196},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42472606897354126},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3621504306793213},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.354988157749176}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:digitalcommons.wku.edu:ijesab-2278","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss7/35","pdf_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss7/35","source":{"id":"https://openalex.org/S4377196460","display_name":"TopSCHOLAR (Western Kentucky University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94339441","host_organization_name":"Western Kentucky University","host_organization_lineage":["https://openalex.org/I94339441"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Exercise Science: Conference Proceedings","raw_type":"text"},{"id":"mag:182780968","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=2278&context=ijesab","pdf_url":null,"source":{"id":"https://openalex.org/S4306513964","display_name":"International Journal of Exercise Science: Conference Proceedings","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Exercise Science: Conference Proceedings","raw_type":null}],"best_oa_location":{"id":"pmh:oai:digitalcommons.wku.edu:ijesab-2278","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss7/35","pdf_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss7/35","source":{"id":"https://openalex.org/S4377196460","display_name":"TopSCHOLAR (Western Kentucky University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94339441","host_organization_name":"Western Kentucky University","host_organization_lineage":["https://openalex.org/I94339441"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Exercise Science: Conference Proceedings","raw_type":"text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.7300000190734863,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W182780968.pdf","grobid_xml":"https://content.openalex.org/works/W182780968.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2476194408","https://openalex.org/W3120860640","https://openalex.org/W2998157048","https://openalex.org/W2345797890","https://openalex.org/W2123880024","https://openalex.org/W4388201181","https://openalex.org/W2293878846","https://openalex.org/W4295129519","https://openalex.org/W2751632373","https://openalex.org/W4407699983"],"abstract_inverted_index":{"Studies":[0],"have":[1],"reported":[2],"an":[3,70],"association":[4,54,201],"between":[5,55,202,217,276,299,306,315],"cortisol":[6,133,166,302,344],"and":[7,58,79,84,119,146,190,215,222,256,281,290,301,374,389],"fatigue":[8,57,83,214,300,313,352,388],"in":[9,60,122,212,312,353,376,394],"multiple":[10],"clinical":[11],"populations,":[12],"including":[13,37],"prostate":[14,277],"cancer":[15],"(PCa).":[16],"Treatment":[17],"options":[18],"for":[19,132,382],"men":[20,61,102,218,223,325,354,377,395],"with":[21,30,62,107,220,226,269,355,378,396],"PCa,":[22,243,248],"such":[23],"as":[24,365],"androgen":[25],"deprivation":[26],"therapy":[27],"(ADT),":[28],"come":[29],"a":[31,49,152,162,330,347,383],"wide":[32],"variety":[33],"of":[34,44,69,77,90,130,186,239,263,340,351,387],"adverse":[35],"effects,":[36],"cancer-related":[38],"fatigue,":[39],"which":[40],"greatly":[41],"impacts":[42,371],"quality":[43],"life":[45],"(QoL).":[46],"PURPOSE:":[47],"Conduct":[48],"preliminary":[50,359],"analysis":[51],"on":[52,82,144,317,322,327],"the":[53,75,88,112,116,136,179,183,191,234,264],"cortisol,":[56,213],"QoL":[59,85,216,375,393],"PCa.":[63,261,356,379],"METHODS:":[64],"This":[65],"study":[66,72,342,381],"is":[67,345,398],"part":[68],"ongoing":[71],"to":[73,151,199,209,391],"determine":[74,200,210],"impact":[76],"PCa":[78,80,108,397],"treatment":[81],"approved":[86],"by":[87,367],"University":[89],"Texas":[91],"Health":[92],"Science":[93],"Center":[94,121],"at":[95,115,154,231],"San":[96,123],"Antonio":[97],"Intuitional":[98],"Review":[99],"Board.":[100],"Twenty-one":[101],"(age:":[103],"69.1\u00b111.55;":[104],"BMI":[105],"28.99\u00b14.78)":[106],"were":[109,266],"recruited":[110],"from":[111],"Urology":[113],"Clinic":[114],"Medical":[117],"Arts":[118],"Research":[120],"Antonio,":[124],"Texas.":[125],"Participants":[126,174],"provided":[127],"~2":[128],"mL":[129],"saliva":[131],"quantification":[134],"using":[135,161],"passive":[137],"drool":[138],"technique.":[139],"Saliva":[140],"was":[141,159,197,207,229,274,297],"immediately":[142],"placed":[143],"ice":[145],"transferred":[147],"within":[148],"4":[149],"hours":[150],"freezer":[153],"-80oC":[155],"until":[156],"analysis.":[157],"Cortisol":[158],"quantified":[160],"commercially":[163],"available":[164],"salivary":[165],"ELISA":[167],"assay":[168],"kit":[169],"(Salimetrics,":[170],"College":[171],"Park,":[172],"PA).":[173],"also":[175],"completed":[176],"three":[177],"questionnaires:":[178],"Brief":[180],"Fatigue":[181],"Inventory,":[182],"Functional":[184],"Assessment":[185],"Chronic":[187],"Illness":[188],"Therapy-Fatigue,":[189],"SF-36.":[192],"Pearson":[193],"product":[194],"moment":[195],"correlation":[196,273,296],"performed":[198],"outcome":[203],"variables.":[204],"Student":[205],"t-test":[206],"used":[208],"differences":[211],"treated":[219,225,268],"ADT":[221,270,318,328],"not":[224,321,326,346],"ADT.":[227,323],"Significance":[228],"set":[230],"pRESULTS:":[232],"Of":[233],"21":[235],"participants,":[236],"9.5%":[237],"(n=2)":[238],"participants":[240,265],"had":[241,246,251,259,329],"metastatic":[242],"4.8%":[244,249],"(n=1)":[245,250],"castration-resistant":[247],"high-grade":[252],"prostatic":[253],"intraepithelial":[254],"neoplasia,":[255],"81%":[257],"(n=17)":[258],"localized":[260],"Twelve":[262],"being":[267],"(57.14%).":[271],"Significant":[272],"observed":[275],"specific":[278],"antigen":[279],"(PSA)":[280],"physical":[282,286,372],"function":[283,373],"(r=-0.728;":[284],"p=.001),":[285,289],"health":[287,335],"(r=-0.729;":[288],"emotional":[291],"problems":[292],"(r=-0.765;":[293],"p=.001).":[294],"No":[295],"found":[298],"levels.":[303],"A":[304],"comparison":[305],"groups":[307],"revealed":[308],"no":[309],"significant":[310],"difference":[311],"level":[314],"those":[316,320],"versus":[319],"However,":[324],"28%":[331],"higher":[332],"average":[333],"general":[334],"score.":[336],"CONCLUSION:":[337],"The":[338],"results":[339],"this":[341],"suggest":[343,361],"strong":[348],"physiological":[349],"measure":[350],"Furthermore,":[357],"these":[358],"data":[360],"that":[362],"advanced":[363],"cancer,":[364],"evident":[366],"elevated":[368],"PSA,":[369],"significantly":[370],"Further":[380],"more":[384],"reliable":[385],"biomarker":[386],"interventions":[390],"improve":[392],"warranted.":[399]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}
