{"id":"https://openalex.org/W182390181","doi":"https://doi.org/10.1007/978-1-4614-8603-9_10","title":"Gene Expression Profiling in Asthma","display_name":"Gene Expression Profiling in Asthma","publication_year":2013,"publication_date":"2013-10-03","ids":{"openalex":"https://openalex.org/W182390181","doi":"https://doi.org/10.1007/978-1-4614-8603-9_10","mag":"182390181","pmid":"https://pubmed.ncbi.nlm.nih.gov/24162908"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4614-8603-9_10","doi":"https://doi.org/10.1007/978-1-4614-8603-9_10","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4614-8603-9_10","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2587906568","display_name":"Heterogeneity in Asthma"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013891093","display_name":"Joanne E. Sordillo","orcid":"https://orcid.org/0000-0002-4966-1796","observed_orcids":["https://orcid.org/0000-0002-4966-1796","https://orcid.org/0009-0004-8702-4925"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanne Sordillo","raw_affiliation_strings":["Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA, rejoa@channing.harvard.edu","Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA, rejoa@channing.harvard.edu","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054459458","display_name":"Benjamin A. Raby","orcid":"https://orcid.org/0000-0003-2206-5748","observed_orcids":["https://orcid.org/0000-0003-2206-5748"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin A. Raby","raw_affiliation_strings":["Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.6607,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.97034655,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"795","issue":null,"first_page":"157","last_page":"181"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.9549999833106995},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.9750000238418579},{"id":"https://openalex.org/keywords/transcriptomics","display_name":"transcriptomics","score":0.9980000257492065},{"id":"https://openalex.org/keywords/oligonucleotide-microarrays","display_name":"oligonucleotide microarrays","score":0.8840000033378601},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"non-coding RNA","score":0.8679999709129333},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.9980000257492065},{"id":"https://openalex.org/keywords/long-intergenic-noncoding-rna","display_name":"long intergenic non-coding RNA","score":0.9620000123977661},{"id":"https://openalex.org/keywords/asthma-biomarkers","display_name":"asthma biomarkers","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6224873065948486},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.5159297585487366},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5120399594306946},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.511078953742981},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4834093153476715},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4611940383911133},{"id":"https://openalex.org/C66782513","wikidata":"https://www.wikidata.org/wiki/Q864601","display_name":"Biomedicine","level":2,"score":0.4392164349555969},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4237593412399292},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3971175253391266},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3140069842338562},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30531713366508484}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016676","descriptor_name":"Macrophages, Alveolar","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016676","descriptor_name":"Macrophages, Alveolar","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D046228","descriptor_name":"Microarray Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4614-8603-9_10","doi":"https://doi.org/10.1007/978-1-4614-8603-9_10","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4614-8603-9_10","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},{"id":"pmid:24162908","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24162908","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in experimental medicine and biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8999999761581421}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W85134005","https://openalex.org/W594872402","https://openalex.org/W649544440","https://openalex.org/W1525354362","https://openalex.org/W1531668109","https://openalex.org/W1533335653","https://openalex.org/W1546952499","https://openalex.org/W1843986322","https://openalex.org/W1970156673","https://openalex.org/W1978995149","https://openalex.org/W1981509058","https://openalex.org/W1995213405","https://openalex.org/W1995634538","https://openalex.org/W2000423446","https://openalex.org/W2001798854","https://openalex.org/W2005129098","https://openalex.org/W2005503891","https://openalex.org/W2009405916","https://openalex.org/W2015064885","https://openalex.org/W2016493165","https://openalex.org/W2021560851","https://openalex.org/W2021701428","https://openalex.org/W2026433349","https://openalex.org/W2027455260","https://openalex.org/W2040784950","https://openalex.org/W2043364653","https://openalex.org/W2043658797","https://openalex.org/W2049446938","https://openalex.org/W2053456085","https://openalex.org/W2053478107","https://openalex.org/W2095594404","https://openalex.org/W2096118746","https://openalex.org/W2098740506","https://openalex.org/W2099079147","https://openalex.org/W2107665951","https://openalex.org/W2107851174","https://openalex.org/W2109071562","https://openalex.org/W2111675378","https://openalex.org/W2117731105","https://openalex.org/W2117994680","https://openalex.org/W2118526609","https://openalex.org/W2120865735","https://openalex.org/W2121211805","https://openalex.org/W2122747013","https://openalex.org/W2123224090","https://openalex.org/W2129274801","https://openalex.org/W2129550988","https://openalex.org/W2130410032","https://openalex.org/W2133094193","https://openalex.org/W2134812217","https://openalex.org/W2137499573","https://openalex.org/W2139345901","https://openalex.org/W2139480869","https://openalex.org/W2141009231","https://openalex.org/W2145905461","https://openalex.org/W2154431984","https://openalex.org/W2154711012","https://openalex.org/W2160697532","https://openalex.org/W2161164720","https://openalex.org/W2161645441","https://openalex.org/W2163117238","https://openalex.org/W2164092307","https://openalex.org/W2164207455","https://openalex.org/W2164891013","https://openalex.org/W2170219300","https://openalex.org/W2170989872","https://openalex.org/W2411515567","https://openalex.org/W2478476484","https://openalex.org/W2506717766","https://openalex.org/W2724249421","https://openalex.org/W4294216491"],"related_works":["https://openalex.org/W3009883064","https://openalex.org/W2034947465","https://openalex.org/W2015064885","https://openalex.org/W2316606025","https://openalex.org/W2807760403","https://openalex.org/W2941226629","https://openalex.org/W2072062736","https://openalex.org/W2944256511","https://openalex.org/W2345306395","https://openalex.org/W2157664759"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}