{"id":"https://openalex.org/W181985306","doi":null,"title":"M14K and M38K malignant pleural mesothelioma cell lines preserve the same claudin-based phenotype in vivo.","display_name":"M14K and M38K malignant pleural mesothelioma cell lines preserve the same claudin-based phenotype in vivo.","publication_year":2013,"publication_date":"2013-03-01","ids":{"openalex":"https://openalex.org/W181985306","mag":"181985306","pmid":"https://pubmed.ncbi.nlm.nih.gov/23422483"},"language":"en","primary_location":{"id":"pmid:23422483","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23422483","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In vivo (Athens, Greece)","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036518593","display_name":"S. Mazouni Chaouche","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133935","display_name":"\u00c9cole Normale Sup\u00e9rieure de Kouba","ror":"https://ror.org/03kh2rb68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210133935"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Siham Chaouche-Mazouni","raw_affiliation_strings":["Department of Biology, Kouba High School, Algiers, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Kouba High School, Algiers, Algeria","institution_ids":["https://openalex.org/I4210133935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027654738","display_name":"Marie\u2010Christine Copin","orcid":"https://orcid.org/0000-0002-4729-7054","observed_orcids":["https://orcid.org/0000-0002-4729-7054"]},"institutions":[{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-Christine Copin","raw_affiliation_strings":["4Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I59807433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073870313","display_name":"Philippe Lassalle","orcid":"https://orcid.org/0000-0001-6434-0344","observed_orcids":["https://orcid.org/0000-0001-6434-0344"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4210098529","display_name":"Center for Infection and Immunity of Lille","ror":"https://ror.org/00dyt5s15","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I3018718406","https://openalex.org/I4210093160","https://openalex.org/I4210096427","https://openalex.org/I4210098529"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Philippe Lassalle","raw_affiliation_strings":["3Lille Center for Infection and Immunity, INSERM U1019-CNRS 8204, Pasteur Institute, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Lille Center for Infection and Immunity, INSERM U1019-CNRS 8204, Pasteur Institute, Lille, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I2800921988","https://openalex.org/I4210098529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026319846","display_name":"Nemcha Leba\u00efli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133935","display_name":"\u00c9cole Normale Sup\u00e9rieure de Kouba","ror":"https://ror.org/03kh2rb68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210133935"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Nemcha Lebaili","raw_affiliation_strings":["1Department of Biology, Kouba High School, Algiers, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Biology, Kouba High School, Algiers, Algeria","institution_ids":["https://openalex.org/I4210133935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032393857","display_name":"Alexis Benjamin Cortot","orcid":"https://orcid.org/0000-0003-0098-2238","observed_orcids":["https://orcid.org/0000-0003-0098-2238"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4210098529","display_name":"Center for Infection and Immunity of Lille","ror":"https://ror.org/00dyt5s15","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I3018718406","https://openalex.org/I4210093160","https://openalex.org/I4210096427","https://openalex.org/I4210098529"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alexis Cortot","raw_affiliation_strings":["3Lille Center for Infection and Immunity, INSERM U1019-CNRS 8204, Pasteur Institute, Lille, France","4Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Lille Center for Infection and Immunity, INSERM U1019-CNRS 8204, Pasteur Institute, Lille, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I2800921988","https://openalex.org/I4210098529"]},{"raw_affiliation_string":"4Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I59807433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089982794","display_name":"Arnaud Scherpereel","orcid":"https://orcid.org/0000-0002-7607-1863","observed_orcids":["https://orcid.org/0000-0002-7607-1863"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4210098529","display_name":"Center for Infection and Immunity of Lille","ror":"https://ror.org/00dyt5s15","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I3018718406","https://openalex.org/I4210093160","https://openalex.org/I4210096427","https://openalex.org/I4210098529"]},{"id":"https://openalex.org/I59807433","display_name":"Universit\u00e9 Lille Nord de France","ror":"https://ror.org/03btvgn05","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I59807433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Arnaud Scherpereel","raw_affiliation_strings":["3Lille Center for Infection and Immunity, INSERM U1019-CNRS 8204, Pasteur Institute, Lille, France","4Lille Nord de France University, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Lille Center for Infection and Immunity, INSERM U1019-CNRS 8204, Pasteur Institute, Lille, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I2800921988","https://openalex.org/I4210098529"]},{"raw_affiliation_string":"4Lille Nord de France University, Lille, France","institution_ids":["https://openalex.org/I59807433"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.23,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.61111816,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"27","issue":"2","first_page":"227","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malignant-pleural-mesothelioma","display_name":"malignant pleural mesothelioma","score":1.0},{"id":"https://openalex.org/keywords/claudin-15","display_name":"claudin-15","score":0.8360000252723694},{"id":"https://openalex.org/keywords/claudin-3","display_name":"claudin-3","score":0.9350000023841858},{"id":"https://openalex.org/keywords/claudin-4","display_name":"claudin-4","score":1.0},{"id":"https://openalex.org/keywords/calretinin","display_name":"calretinin","score":0.7929999828338623},{"id":"https://openalex.org/keywords/cancer-cell-lines","display_name":"cancer cell lines","score":0.7689999938011169},{"id":"https://openalex.org/keywords/tumor-xenografts","display_name":"tumor xenografts","score":0.9070000052452087},{"id":"https://openalex.org/keywords/lung-adenocarcinoma","display_name":"lung adenocarcinoma","score":0.8889999985694885}],"concepts":[{"id":"https://openalex.org/C2777407522","wikidata":"https://www.wikidata.org/wiki/Q1077603","display_name":"Mesothelioma","level":2,"score":0.8294585347175598},{"id":"https://openalex.org/C51872919","wikidata":"https://www.wikidata.org/wiki/Q420863","display_name":"Claudin","level":3,"score":0.7986943125724792},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.6949710249900818},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.6932598352432251},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.655899703502655},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6205670237541199},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5667136907577515},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5147340297698975},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.49787068367004395},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.4713142514228821},{"id":"https://openalex.org/C2780635560","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Neoplasm","level":2,"score":0.43950018286705017},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3847055733203888},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3008643388748169},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23427781462669373},{"id":"https://openalex.org/C177779419","wikidata":"https://www.wikidata.org/wiki/Q1053832","display_name":"Tight junction","level":2,"score":0.13797226548194885},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08236247301101685},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.03832852840423584},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000086002","descriptor_name":"Mesothelioma, Malignant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009374","descriptor_name":"Neoplasms, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009374","descriptor_name":"Neoplasms, Experimental","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009374","descriptor_name":"Neoplasms, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010997","descriptor_name":"Pleural Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010997","descriptor_name":"Pleural Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010997","descriptor_name":"Pleural Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016513","descriptor_name":"Mice, SCID","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023041","descriptor_name":"Xenograft Model Antitumor Assays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057167","descriptor_name":"Claudins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064030","descriptor_name":"S100 Calcium Binding Protein G","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D064032","descriptor_name":"Calbindin 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":1,"locations":[{"id":"pmid:23422483","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23422483","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In vivo (Athens, Greece)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1589010135","https://openalex.org/W1926327739","https://openalex.org/W1966184698","https://openalex.org/W1971170437","https://openalex.org/W1971760530","https://openalex.org/W1980760878","https://openalex.org/W2013645436","https://openalex.org/W2036848524","https://openalex.org/W2076992005","https://openalex.org/W2100657891","https://openalex.org/W2129304235","https://openalex.org/W2155358100","https://openalex.org/W2157379439","https://openalex.org/W2159791426","https://openalex.org/W2164216532","https://openalex.org/W2168220121","https://openalex.org/W2170505336"],"related_works":["https://openalex.org/W6989892497","https://openalex.org/W2981470588","https://openalex.org/W2174606487","https://openalex.org/W2057177169","https://openalex.org/W2894872374","https://openalex.org/W2027884905","https://openalex.org/W2160825631","https://openalex.org/W6989945023","https://openalex.org/W2602048237","https://openalex.org/W7099931607"],"abstract_inverted_index":{"BACKGROUND:":[0],"Malignant":[1],"pleural":[2],"mesothelioma":[3,18],"(MPM)":[4],"is":[5,43],"an":[6,135],"aggressive":[7],"neoplasm":[8],"with":[9],"few":[10],"treatment":[11],"options.":[12],"Reliable":[13],"tumour":[14,90],"cell":[15,83,104,128],"lines":[16,84,105],"for":[17,28],"research":[19],"are":[20,138],"rare.":[21],"Claudins":[22],"seem":[23],"to":[24,39],"be":[25],"attractive":[26],"targets":[27],"cancer":[29],"therapy.":[30],"AIM:":[31],"To":[32],"establish":[33],"a":[34],"claudin-based":[35],"MPM":[36,64,80,87,97,149],"phenotype":[37,98],"and":[38,47,54,61,66,73,85,102,109,126,141],"verify":[40],"whether":[41,130],"it":[42],"preserved":[44],"in":[45,48,63,79,86,120,131,134,143,148],"vitro":[46,132],"vivo.":[49],"MATERIALS":[50],"AND":[51],"METHODS:":[52],"Claudin-3":[53],"-4":[55,72],"expression":[56,75],"was":[57,76,99],"examined":[58],"by":[59],"immunohistochemistry":[60],"immunoblotting":[62],"(n=15)":[65],"lung":[67],"adenocarcinoma":[68,82],"(n=5)":[69],"specimens.":[70],"Claudin-3,":[71],"-15":[74],"also":[77],"assessed":[78],"versus":[81,88],"adenocarcinoma-derived":[89],"xenografts":[91],"mouse":[92,122],"models.":[93,123],"RESULTS:":[94],"A":[95],"defined":[96],"established:":[100],"M14K":[101,125],"M38K":[103,127],"highly":[106],"express":[107],"Claudin-15":[108],"calretinin":[110],"but":[111],"not":[112],"claudin-3":[113],"nor":[114],"claudin-4.":[115],"Similar":[116],"results":[117],"were":[118],"obtained":[119],"xenograft":[121],"CONCLUSION:":[124],"lines,":[129],"or":[133],"animal":[136],"model":[137],"representative":[139],"models":[140],"appropriate":[142],"exploring":[144],"new":[145],"therapeutic":[146],"strategies":[147],"that":[150],"may":[151],"target":[152],"claudins.":[153]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}