{"id":"https://openalex.org/W18164208","doi":null,"title":"[Saturin - effective vegetative remedy in treatment of type 2 diabetes mellitus].","display_name":"[Saturin - effective vegetative remedy in treatment of type 2 diabetes mellitus].","publication_year":2012,"publication_date":"2012-02-01","ids":{"openalex":"https://openalex.org/W18164208","mag":"18164208","pmid":"https://pubmed.ncbi.nlm.nih.gov/22466541"},"language":"ru","primary_location":{"id":"pmid:22466541","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22466541","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Georgian medical news","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111672654","display_name":"\u042d. \u041f. \u041a\u0435\u043c\u0435\u0440\u0442\u0435\u043b\u0438\u0434\u0437\u0435","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7848551","display_name":"Tbilisi State Medical University","ror":"https://ror.org/020jbrt22","country_code":"GE","type":"education","lineage":["https://openalex.org/I7848551"]}],"countries":["GE"],"is_corresponding":false,"raw_author_name":"E Kemertelidze","raw_affiliation_strings":["Tbilisi State Medical University, I. Kutateladze Institute of Pharmacochemistry, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tbilisi State Medical University, I. Kutateladze Institute of Pharmacochemistry, Georgia","institution_ids":["https://openalex.org/I7848551"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088135995","display_name":"\u0422. \u0413. \u0421\u0430\u0433\u0430\u0440\u0435\u0438\u0448\u0432\u0438\u043b\u0438","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Sagareishvili","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000960002","display_name":"V Syrov","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Syrov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039074323","display_name":"Zainab Abdurakhmanovna Khushbaktova","orcid":"https://orcid.org/0000-0002-1725-5590","observed_orcids":["https://orcid.org/0000-0002-1725-5590"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z Khushbaktova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042250935","display_name":"Liana Tsutskiridze","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Tsutskiridze","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5071040530","display_name":"Ramaz B. Kurashvili","orcid":"https://orcid.org/0000-0003-1509-1956","observed_orcids":["https://orcid.org/0000-0003-1509-1956"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Kurashvili","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6178,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.69027352,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":null,"issue":"203","first_page":"47","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/satureja-hortensis","display_name":"Satureja hortensis","score":0.9490000009536743},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hypoglycemic-activity","display_name":"hypoglycemic activity","score":0.9179999828338623},{"id":"https://openalex.org/keywords/alloxan-induced-diabetes","display_name":"alloxan-induced diabetes","score":0.8029999732971191},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.7350000143051147},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.871999979019165},{"id":"https://openalex.org/keywords/chlorogenic-acid","display_name":"chlorogenic acid","score":0.8240000009536743},{"id":"https://openalex.org/keywords/rosmarinic-acid","display_name":"rosmarinic acid","score":0.9980000257492065},{"id":"https://openalex.org/keywords/thymol","display_name":"thymol","score":0.8690000176429749},{"id":"https://openalex.org/keywords/essential-oils","display_name":"essential oils","score":0.7910000085830688},{"id":"https://openalex.org/keywords/plant-aqueous-extracts","display_name":"aqueous plant extract","score":0.8360000252723694},{"id":"https://openalex.org/keywords/herbal-medicine","display_name":"herbal medicine","score":0.4699999988079071},{"id":"https://openalex.org/keywords/drug-development","display_name":"drug development","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C2776080593","wikidata":"https://www.wikidata.org/wiki/Q415011","display_name":"Luteolin","level":4,"score":0.7430187463760376},{"id":"https://openalex.org/C2780642067","wikidata":"https://www.wikidata.org/wiki/Q408883","display_name":"Thymol","level":3,"score":0.6762593984603882},{"id":"https://openalex.org/C2780676017","wikidata":"https://www.wikidata.org/wiki/Q225543","display_name":"Carvacrol","level":3,"score":0.6513892412185669},{"id":"https://openalex.org/C2778771215","wikidata":"https://www.wikidata.org/wiki/Q50380051","display_name":"Rosmarinic acid","level":3,"score":0.6343948841094971},{"id":"https://openalex.org/C2780366203","wikidata":"https://www.wikidata.org/wiki/Q22858","display_name":"Satureja","level":3,"score":0.6090941429138184},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5613834261894226},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.469743549823761},{"id":"https://openalex.org/C2781005915","wikidata":"https://www.wikidata.org/wiki/Q417701","display_name":"Alloxan","level":3,"score":0.46381041407585144},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.438441663980484},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.41962358355522156},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4058058261871338},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3919960856437683},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3258320093154907},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.235458105802536},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.21420353651046753},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.13878920674324036},{"id":"https://openalex.org/C2777278459","wikidata":"https://www.wikidata.org/wiki/Q170885","display_name":"Essential oil","level":2,"score":0.1366778314113617},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003921","descriptor_name":"Diabetes Mellitus, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017277","descriptor_name":"Drug Approval","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D031362","descriptor_name":"Satureja","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:22466541","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22466541","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Georgian medical news","raw_type":"Clinical Trial"},{"id":"mag:18164208","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22466541","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1238112858","https://openalex.org/W4317241532","https://openalex.org/W2306158436","https://openalex.org/W3136335404","https://openalex.org/W2012003367","https://openalex.org/W2271444810","https://openalex.org/W1988504956","https://openalex.org/W4407290070","https://openalex.org/W2898256176","https://openalex.org/W4366207686"],"abstract_inverted_index":{"A":[0],"chemical":[1],"investigation":[2,101],"of":[3,48,54,65,75,83,91,93,102,158,162,170,187,193,224,227],"plant":[4,95],"Satureja":[5],"hortensis":[6],"L.":[7],"-":[8,37,153],"garden":[9],"savory":[10],"(GS)":[11],"has":[12,97,165],"been":[13,98,166],"carried":[14,107],"out.":[15],"It":[16],"is":[17,22,61,142,182,216],"established":[18],"that":[19,129],"the":[20,46,49,88,103,130,145,185,219,225],"GS":[21,60,66,84,104,131,163],"rich":[23],"in":[24,59,144,175,202,209],"phenolic":[25],"compounds.":[26],"Flavonoids":[27],"apigenin,":[28],"luteolin,":[29],"cinaroside,":[30],"luteolin-glucuronide,":[31],"luteolin-rutinoside,":[32],"isoroifolin":[33],"and":[34,40,56,77,112,141,190,198,221],"phenylcarbonic":[35,57],"acids":[36,58],"chlorogenic":[38],"acid":[39,42],"rosmarinic":[41],"were":[43],"isolated":[44],"from":[45],"leaves":[47,64],"plant.":[50],"The":[51,63,126,180],"total":[52],"content":[53],"flavonoids":[55],"1,6-1,7%.":[62],"contain":[67],"up":[68],"to":[69],"1%":[70],"essential":[71],"oil":[72],"consisting":[73],"mainly":[74],"thymol":[76],"methyl":[78],"carvacrol.":[79],"Dry":[80],"aqueous":[81,160],"extract":[82,105,132,161],"leaves,":[85,164],"which":[86],"retains":[87],"full":[89],"range":[90],"substances":[92],"raw":[94],"material":[96],"obtained.":[99],"Pharmacological":[100],"was":[106,120],"out":[108],"on":[109],"intact":[110],"animals":[111,113],"with":[114,211],"experimental":[115],"alloxan":[116],"diabetes.":[117],"Antidiabetic":[118],"Arfasetine":[119],"chosen":[121],"as":[122],"a":[123],"reference":[124],"drug.":[125],"study":[127],"revealed":[128],"exhibits":[133],"hypoglycemic":[134,213],"activity":[135],"significantly":[136],"reducing":[137],"blood":[138],"sugar":[139],"levels":[140],"safe":[143],"long":[146],"run.":[147],"Drug":[148],"dosage":[149],"form":[150],"named":[151],"saturin":[152],"capsules":[154],"containing":[155],"0,33":[156],"g":[157],"dried":[159],"developed.":[167],"Clinical":[168],"trials":[169],"Saturin":[171,215],"confirmed":[172],"its":[173],"effiacy":[174],"diabetes":[176,205],"mellitus":[177],"type":[178,203],"2.":[179],"drug":[181],"registered":[183],"by":[184],"Ministry":[186],"Health,":[188],"Labour":[189],"Social":[191],"Welfare":[192],"Georgia":[194],"(Registration":[195],"Certificate":[196],"\u2116003658)":[197],"approved":[199],"for":[200],"use":[201],"2":[204],"either":[206],"independently":[207],"or":[208],"combination":[210],"other":[212],"agents.":[214],"manufactured":[217],"at":[218],"Experimental":[220],"Production":[222],"Facility":[223],"Institute":[226],"Pharmacochemistry.":[228]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}