{"id":"https://openalex.org/W181590604","doi":null,"title":"Long-term survival following radical and palliative treatment of patients with carcinoma of the pancreas and papilla of Vater--the prognostic factors influencing the long-term results. A prospective multicentre study.","display_name":"Long-term survival following radical and palliative treatment of patients with carcinoma of the pancreas and papilla of Vater--the prognostic factors influencing the long-term results. A prospective multicentre study.","publication_year":1993,"publication_date":"1993-04-01","ids":{"openalex":"https://openalex.org/W181590604","mag":"181590604","pmid":"https://pubmed.ncbi.nlm.nih.gov/7684003"},"language":"en","primary_location":{"id":"pmid:7684003","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7684003","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109358272","display_name":"K\u00e5re E. Bakkevold","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800740805","display_name":"Haukeland University Hospital","ror":"https://ror.org/03np4e098","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2800740805"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"K E Bakkevold","raw_affiliation_strings":["Department of Surgery, Haukeland University Hospital, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Haukeland University Hospital, Norway","institution_ids":["https://openalex.org/I2800740805"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067175488","display_name":"B Kambestad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Kambestad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.3422,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.89492119,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"19","issue":"2","first_page":"147","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-ductal-adenocarcinoma","display_name":"pancreatic ductal adenocarcinoma","score":0.9639999866485596},{"id":"https://openalex.org/keywords/long-term-survival","display_name":"long-term survival","score":0.800000011920929},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9470000267028809},{"id":"https://openalex.org/keywords/pancreaticoduodenectomy","display_name":"pancreaticoduodenectomy","score":0.8539999723434448},{"id":"https://openalex.org/keywords/total-pancreatectomy","display_name":"total pancreatectomy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/palliative-bypass","display_name":"palliative bypass","score":0.7179999947547913},{"id":"https://openalex.org/keywords/radical-surgery","display_name":"radical surgery","score":0.8339999914169312},{"id":"https://openalex.org/keywords/tnm-staging","display_name":"TNM staging","score":0.8140000104904175},{"id":"https://openalex.org/keywords/karnofsky-performance-status","display_name":"Karnofsky performance status","score":0.9279999732971191},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9358564019203186},{"id":"https://openalex.org/C134984996","wikidata":"https://www.wikidata.org/wiki/Q14404864","display_name":"Major duodenal papilla","level":2,"score":0.8755792379379272},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.5599878430366516},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5576159358024597},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.5291595458984375},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.5260902643203735},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5082568526268005},{"id":"https://openalex.org/C2776283816","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Survival rate","level":2,"score":0.5002467632293701},{"id":"https://openalex.org/C2776874909","wikidata":"https://www.wikidata.org/wiki/Q7280497","display_name":"Radical surgery","level":3,"score":0.4909878075122833},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.42941486835479736},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.41456782817840576},{"id":"https://openalex.org/C2780840399","wikidata":"https://www.wikidata.org/wiki/Q594066","display_name":"Ampulla of Vater","level":3,"score":0.4126223921775818},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31636083126068115},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1508505940437317},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003138","descriptor_name":"Common Bile Duct Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D003138","descriptor_name":"Common Bile Duct Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D003138","descriptor_name":"Common Bile Duct Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010166","descriptor_name":"Palliative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014670","descriptor_name":"Ampulla of Vater","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:7684003","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7684003","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology","raw_type":"Journal Article"},{"id":"mag:181590604","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7684003","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2053544486","https://openalex.org/W2416143276","https://openalex.org/W2401151394","https://openalex.org/W2396719970","https://openalex.org/W129473659","https://openalex.org/W2031562722","https://openalex.org/W1530372471","https://openalex.org/W2419621625","https://openalex.org/W2363621835","https://openalex.org/W1538092430"],"abstract_inverted_index":{"Between":[0],"1984-1987,":[1],"472":[2],"Norwegian":[3],"patients":[4,48,62],"with":[5,49,63],"histologically":[6],"or":[7,35,114],"cytologically":[8],"verified":[9],"adenocarcinoma":[10],"of":[11,19,47,61,91,102,118,127,162],"the":[12],"pancreas":[13],"(n":[14,21,32,38],"=":[15,22,33,39,133,144,168],"442)":[16],"and":[17,45,51,57,65,70,76,78,96,106,138,153,164,183,193],"papilla":[18,52,66,103],"Vater":[20],"30)":[23],"were":[24,41,68,94,121,156,188],"prospectively":[25],"accrued.":[26],"Radical":[27,112],"surgery,":[28],"i.e.":[29],"Whipple's":[30,151],"procedure":[31],"80)":[34],"total":[36,154],"pancreatectomy":[37,155],"28)":[40],"performed":[42],"in":[43,135,146],"19%":[44],"80%":[46],"pancreatic":[50,64,92,119],"carcinoma,":[53],"respectively.":[54,84,149,170],"The":[55,85],"1-":[56],"5-year":[58],"survival":[59,73,81,99,109,126,161],"rate":[60],"carcinoma":[67,93,104,120],"15":[69],"0.2%,":[71],"median":[72,80,98,108],"4.5":[74],"months;":[75,101],"66":[77],"15%,":[79],"17":[82],"months,":[83],"corresponding":[86],"results":[87],"following":[88],"radical":[89,194],"surgery":[90,113],"45":[95],"1%,":[97],"11.4":[100],"78":[105],"20%,":[107],"38.1":[110],"months.":[111],"a":[115,124,159,175,189],"palliative":[116],"bypass":[117],"followed":[122,157],"by":[123,158],"mean":[125,160],"20.1":[128],"vs":[129,140],"9.1":[130],"months":[131,142,166],"(P":[132,143,167],"0.03)":[134],"Stage":[136,147],"I":[137],"15.1":[139],"7.5":[141],"0.004)":[145],"III,":[148],"A":[150],"operation":[152],"16.7":[163],"18.3":[165],"0.5),":[169],"Dismal":[171],"prognostic":[172],"factors":[173,187],"were:":[174],"distal":[176],"tumour":[177],"site,":[178],"high":[179,190],"TNM":[180],"stage":[181],"grouping":[182],"weight":[184],"loss.":[185],"Beneficial":[186],"Karnofsky's":[191],"index":[192],"surgery.":[195]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}