{"id":"https://openalex.org/W1808396121","doi":null,"title":"Biomarkers of Suicide Risk in Psychosis","display_name":"Biomarkers of Suicide Risk in Psychosis","publication_year":2009,"publication_date":"2009-11-27","ids":{"openalex":"https://openalex.org/W1808396121","mag":"1808396121"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/26923411","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Biomarkers_of_suicide_risk_in_psychosis/26923411","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10616/37911","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054184978","display_name":"Andreas Carlborg","orcid":"https://orcid.org/0000-0001-9719-3045","observed_orcids":["https://orcid.org/0000-0001-9719-3045"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Andreas Carlborg","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9719-3045","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5054184978"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10376","display_name":"Suicide and Self-Harm Studies","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10376","display_name":"Suicide and Self-Harm Studies","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/suicide-risk","display_name":"suicide risk","score":0.8569999933242798},{"id":"https://openalex.org/keywords/suicide-attempts","display_name":"suicide attempts","score":0.49900001287460327},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7020000219345093},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"cerebrospinal fluid","score":0.8399999737739563},{"id":"https://openalex.org/keywords/5-hydroxyindoleacetic-acid","display_name":"5-hydroxyindoleacetic acid","score":0.9490000009536743},{"id":"https://openalex.org/keywords/homovanillic-acid","display_name":"homovanillic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/kynurenic-acid","display_name":"kynurenic acid","score":0.9649999737739563},{"id":"https://openalex.org/keywords/monoamine-metabolites","display_name":"monoamine metabolites","score":0.9710000157356262},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5389999747276306},{"id":"https://openalex.org/keywords/gender-differences","display_name":"gender differences","score":0.7229999899864197},{"id":"https://openalex.org/keywords/long-term-follow-up","display_name":"long-term follow-up","score":0.8080000281333923},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.4699999988079071},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.39800000190734863},{"id":"https://openalex.org/keywords/mood-disorders","display_name":"mood disorders","score":0.5600000023841858},{"id":"https://openalex.org/keywords/hospitalized-patients","display_name":"hospitalized patients","score":0.40700000524520874},{"id":"https://openalex.org/keywords/causes-of-death","display_name":"causes of death","score":0.656000018119812},{"id":"https://openalex.org/keywords/sweden","display_name":"Sweden","score":0.41600000858306885}],"concepts":[{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.6778383255004883},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.6357846260070801},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.5951371192932129},{"id":"https://openalex.org/C2780842732","wikidata":"https://www.wikidata.org/wiki/Q3518184","display_name":"Suicide attempt","level":4,"score":0.5564817190170288},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5046511888504028},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.4794572591781616},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.43989983201026917},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.43099379539489746},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4125766158103943},{"id":"https://openalex.org/C526869908","wikidata":"https://www.wikidata.org/wiki/Q3298118","display_name":"Suicide prevention","level":3,"score":0.3599417805671692},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3223799467086792},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.1284390687942505},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/26923411","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Biomarkers_of_suicide_risk_in_psychosis/26923411","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:openarchive.ki.se:10616/37911","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/37911","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:1808396121","doi":null,"is_oa":false,"landing_page_url":"http://publications.ki.se/xmlui/bitstream/handle/10616/37911/thesis.pdf?sequence=1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openarchive.ki.se:10616/37911","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/37911","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":109,"referenced_works":["https://openalex.org/W17887401","https://openalex.org/W86297474","https://openalex.org/W167467255","https://openalex.org/W204779288","https://openalex.org/W283318598","https://openalex.org/W331038839","https://openalex.org/W1536172757","https://openalex.org/W1588259698","https://openalex.org/W1588883944","https://openalex.org/W1702140452","https://openalex.org/W1924228574","https://openalex.org/W1956615634","https://openalex.org/W1964522439","https://openalex.org/W1968884554","https://openalex.org/W1971244482","https://openalex.org/W1976955283","https://openalex.org/W1980528794","https://openalex.org/W1989405621","https://openalex.org/W1990830006","https://openalex.org/W1995549341","https://openalex.org/W1996254896","https://openalex.org/W1999070612","https://openalex.org/W2000277154","https://openalex.org/W2003586939","https://openalex.org/W2003625288","https://openalex.org/W2006100396","https://openalex.org/W2006675313","https://openalex.org/W2006851386","https://openalex.org/W2013870426","https://openalex.org/W2016150080","https://openalex.org/W2017661386","https://openalex.org/W2019924051","https://openalex.org/W2024829920","https://openalex.org/W2028370746","https://openalex.org/W2045596191","https://openalex.org/W2047660590","https://openalex.org/W2047791419","https://openalex.org/W2048887295","https://openalex.org/W2055665829","https://openalex.org/W2056628193","https://openalex.org/W2057008284","https://openalex.org/W2059683057","https://openalex.org/W2060359473","https://openalex.org/W2064157974","https://openalex.org/W2065983268","https://openalex.org/W2067322948","https://openalex.org/W2067494870","https://openalex.org/W2067640820","https://openalex.org/W2068268552","https://openalex.org/W2068668914","https://openalex.org/W2070135673","https://openalex.org/W2071060747","https://openalex.org/W2072550600","https://openalex.org/W2079447662","https://openalex.org/W2079473907","https://openalex.org/W2082250521","https://openalex.org/W2083396932","https://openalex.org/W2083524390","https://openalex.org/W2086004263","https://openalex.org/W2087126681","https://openalex.org/W2088665444","https://openalex.org/W2093265452","https://openalex.org/W2093531478","https://openalex.org/W2097031522","https://openalex.org/W2098470558","https://openalex.org/W2099376450","https://openalex.org/W2099635835","https://openalex.org/W2101269099","https://openalex.org/W2101700972","https://openalex.org/W2101702109","https://openalex.org/W2102241581","https://openalex.org/W2105527159","https://openalex.org/W2107256884","https://openalex.org/W2113463828","https://openalex.org/W2118643787","https://openalex.org/W2119940130","https://openalex.org/W2121843306","https://openalex.org/W2131932927","https://openalex.org/W2135018545","https://openalex.org/W2137589027","https://openalex.org/W2137625559","https://openalex.org/W2139695972","https://openalex.org/W2140156016","https://openalex.org/W2140853541","https://openalex.org/W2144334285","https://openalex.org/W2146118647","https://openalex.org/W2146600199","https://openalex.org/W2149044594","https://openalex.org/W2149288810","https://openalex.org/W2150633664","https://openalex.org/W2152739348","https://openalex.org/W2154244002","https://openalex.org/W2154401220","https://openalex.org/W2154948378","https://openalex.org/W2157574219","https://openalex.org/W2160882381","https://openalex.org/W2161989821","https://openalex.org/W2166384797","https://openalex.org/W2166945572","https://openalex.org/W2167000826","https://openalex.org/W2167169840","https://openalex.org/W2167512497","https://openalex.org/W2168796881","https://openalex.org/W2169904884","https://openalex.org/W2172250017","https://openalex.org/W2183731204","https://openalex.org/W2231105787","https://openalex.org/W2299897877","https://openalex.org/W4406433987"],"related_works":["https://openalex.org/W2147003591","https://openalex.org/W2167840584","https://openalex.org/W2136154580","https://openalex.org/W4301735218","https://openalex.org/W2067322948","https://openalex.org/W2068268552","https://openalex.org/W1588883944","https://openalex.org/W2000277154","https://openalex.org/W1999468411","https://openalex.org/W2013870426"],"abstract_inverted_index":{"Suicide":[0,388],"and":[1,18,35,55,88,100,130,139,159,178,221,233,258,277,287,294,346,440,470,494],"attempted":[2,256,290,438],"suicide":[3,13,34,36,53,114,150,156,191,231,242,257,288,321,329,377,406,408,439,441,495],"are":[4,134],"major":[5],"health":[6],"problems.":[7],"Approximately":[8],"1400":[9],"people":[10],"die":[11],"from":[12,91,195,204,305],"every":[14],"year":[15],"in":[16,63,73,116,249,253,330,334,355,379,410,443,474,497],"Sweden":[17],"ten":[19],"times":[20,247],"more":[21],"attempt":[22,54],"suicide.":[23,227,240,266,291,319],"Patients":[24,308],"with":[25,76,84,169,309,341,352],"schizophrenia":[26,85,117,170,310,356,380,411,444,475,498],"spectrum":[27,86,118,311,357,381,412,445,476,499],"psychosis":[28,87,312,358],"have":[29,38,67,81,313],"an":[30],"increased":[31],"risk":[32,48,115,151,243,263,300,317,326,378,409,442,496],"of":[33,60,94,98,106,122,146,185,200,207,217,230,235,275,318,361,421],"rates":[37],"been":[39,68],"suggested":[40],"to":[41,70,110,136,140,338],"be":[42],"as":[43,45,153],"high":[44,315],"10%.":[46],"Important":[47],"factors":[49,148,264],"include":[50],"a":[51,154,182,299,314,323],"prior":[52,155,190],"depressive":[56],"disorder.":[57],"Low":[58],"concentrations":[59,121,274,286,296,348],"monoamine":[61,125,472],"metabolites":[62,126,473],"cerebrospinal":[64],"fluid":[65],"(CSF)":[66],"related":[69,135],"suicidal":[71,137,353],"behavior":[72,138,354],"patients":[74,83,339],"diagnosed":[75,340],"mood":[77,342],"disorders.":[78],"Few":[79],"studies":[80],"investigated":[82],"they":[89],"suffer":[90],"small":[92],"numbers":[93],"patients,":[95],"short":[96],"periods":[97],"follow-up":[99,212],"contradictory":[101],"results.":[102],"The":[103,144,241],"main":[104],"objective":[105],"this":[107],"study":[108],"was":[109,164,193,244,322],"investigate":[111],"the":[112,123,141,196,205,211,236],"long-term":[113,316],"psychosis,":[119],"whether":[120],"CSF":[124,160,273,284,292,344,436,471,491],"5-hydroxyindoleacetic":[127],"acid":[128,132,162,493],"(5-HIAA)":[129],"homovanillic":[131],"(HVA)":[133],"overall":[142],"mortality.":[143],"importance":[145],"other":[147],"influencing":[149],"such":[152],"attempt,":[157],"gender":[158,260],"kynurenic":[161,492],"(KYNA)":[163],"also":[165],"investigated.":[166],"Inpatients":[167],"(n=385)":[168],"like":[171],"symptoms":[172],"were":[173,202,261,268,297,349],"lumbar":[174],"punctured":[175],"at":[176],"admittance":[177],"followed":[179],"up":[180],"for":[181,265,302,328],"median":[183],"period":[184,213],"26":[186],"years.":[187],"Information":[188],"about":[189],"attempts":[192],"retrieved":[194],"medical":[197],"records.":[198],"Causes":[199,206],"death":[201,304,469],"obtained":[203],"Death":[208],"Register.":[209],"During":[210],"nearly":[214],"equal":[215],"percentages":[216],"men":[218],"(6.5":[219],"%)":[220,224],"women":[222],"(6.9":[223],"died":[225,238],"by":[226,239,385],"Eighteen":[228],"percent":[229],"attempters":[232,251],"2%":[234],"non-attempters":[237],"almost":[245],"three":[246],"higher":[248],"male":[250,259],"than":[252],"females.":[254],"Thus,":[255],"significant":[262],"There":[267],"neither":[269],"any":[270],"associations":[271],"between":[272,283],"5-HIAA":[276,293,345],"HVA,":[278],"or":[279,289],"their":[280],"ratio,":[281],"nor":[282],"KYNA":[285],"HVA":[295,347],"not":[298,350],"factor":[301,327],"early":[303],"natural":[306],"causes.":[307],"Attempted":[320,405],"very":[324],"important":[325],"both":[331],"genders,":[332],"especially":[333],"males.":[335],"In":[336],"contrast":[337],"disorders,":[343],"associated":[351],"patients.":[359],"List":[360],"scientific":[362],"papers":[363],"I.":[364],"Carlborg":[365,394,425,457,480],"A,":[366,395,426,458,481],"Jokinen":[367,396,427,459,482],"J,":[368,397,428,460,483],"J\u00f6nsson":[369,400,431,463,484],"EG,":[370,401,432,464,485],"Nordstrom":[371],"AL,":[372,399,430,462],"N\u00f6rdstrom":[373],"P":[374,403,434,466,489],"(2008).":[375],"Long-term":[376],"psychoses:":[382],"survival":[383],"analysis":[384],"gender.":[386],"Arch":[387],"Res.":[389,448],"12(4):":[390],"347-51":[391],"https://pubmed.ncbi.nlm.nih.gov/18828038":[392],"II.":[393],"Nordstr\u00f6m":[398,402,429,433,461,465,488],"(2009).":[404,435,467,490],"predicts":[407],"psychosis.":[413,446,477,500],"Nord":[414],"J":[415],"Psychiatry.":[416],"Nov":[417],"2:":[418],"Epub":[419,451],"ahead":[420],"print":[422],"https://pubmed.ncbi.nlm.nih.gov/19883197":[423],"III.":[424],"5-HIAA,":[437],"Schizophr":[447],"112(1-3):":[449],"80-5.":[450],"2009":[452],"May":[453],"1":[454],"https://pubmed.ncbi.nlm.nih.gov/19410429":[455],"IV.":[456],"Early":[468],"[Submitted]":[478,501],"V.":[479],"Erhardt":[486],"S,":[487]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
