{"id":"https://openalex.org/W1805081380","doi":null,"title":"Fluorinated Nanoparticles: A Novel Technology Platform for Multimodal Biomedical Imaging Applications","display_name":"Fluorinated Nanoparticles: A Novel Technology Platform for Multimodal Biomedical Imaging Applications","publication_year":2010,"publication_date":"2010-07-26","ids":{"openalex":"https://openalex.org/W1805081380","mag":"1805081380"},"language":"en","primary_location":{"id":"pmh:oai:kuscholarworks.ku.edu:1808/6960","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1808/6960","pdf_url":null,"source":{"id":"https://openalex.org/S4306400421","display_name":"KU ScholarWorks (The University of Kansas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I146416000","host_organization_name":"University of Kansas","host_organization_lineage":["https://openalex.org/I146416000"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065702930","display_name":"Mark M. Bailey","orcid":"https://orcid.org/0000-0001-8950-1431","observed_orcids":["https://orcid.org/0000-0001-8950-1431"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mark M. Bailey","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8950-1431","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5065702930"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.22360000014305115,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.22360000014305115,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.08579999953508377,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10947","display_name":"Fluorine in Organic Chemistry","score":0.07370000332593918,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorinated-nanoparticles","display_name":"fluorinated nanoparticles","score":1.0},{"id":"https://openalex.org/keywords/19f-mri-contrast-agents","display_name":"19F MRI contrast agents","score":0.8999999761581421},{"id":"https://openalex.org/keywords/secondary-ion-mass-spectrometry-imaging","display_name":"secondary ion mass spectrometry imaging","score":0.8640000224113464},{"id":"https://openalex.org/keywords/19f-nmr","display_name":"19F NMR","score":0.8130000233650208},{"id":"https://openalex.org/keywords/fluorescence-imaging","display_name":"fluorescence imaging","score":0.5699999928474426},{"id":"https://openalex.org/keywords/icam-1","display_name":"ICAM-1","score":0.8679999709129333},{"id":"https://openalex.org/keywords/t-cell-recruitment","display_name":"T cell recruitment","score":0.7559999823570251},{"id":"https://openalex.org/keywords/inflammation-imaging","display_name":"inflammation imaging","score":0.7110000252723694},{"id":"https://openalex.org/keywords/antibody-conjugated-nanoparticles","display_name":"antibody-conjugated nanoparticles","score":0.6520000100135803},{"id":"https://openalex.org/keywords/cellular-uptake","display_name":"cellular uptake","score":0.5960000157356262},{"id":"https://openalex.org/keywords/multimodal-imaging","display_name":"multimodal imaging","score":0.47099998593330383}],"concepts":[{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5274677276611328},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.48036274313926697},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3565842807292938},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3358911871910095},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2843572497367859}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:kuscholarworks.ku.edu:1808/6960","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1808/6960","pdf_url":null,"source":{"id":"https://openalex.org/S4306400421","display_name":"KU ScholarWorks (The University of Kansas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I146416000","host_organization_name":"University of Kansas","host_organization_lineage":["https://openalex.org/I146416000"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},{"id":"mag:1805081380","doi":null,"is_oa":false,"landing_page_url":"https://kuscholarworks.ku.edu/bitstream/1808/6960/1/Bailey_ku_0099D_11072_DATA_1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6201000213623047}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":92,"referenced_works":["https://openalex.org/W560314225","https://openalex.org/W1576050834","https://openalex.org/W1578663184","https://openalex.org/W1578986447","https://openalex.org/W1871308790","https://openalex.org/W1907876474","https://openalex.org/W1935017661","https://openalex.org/W1964270561","https://openalex.org/W1967551950","https://openalex.org/W1967624107","https://openalex.org/W1967785970","https://openalex.org/W1968947842","https://openalex.org/W1976808592","https://openalex.org/W1981502499","https://openalex.org/W1982005887","https://openalex.org/W1986269836","https://openalex.org/W1986879518","https://openalex.org/W1991262479","https://openalex.org/W1995975581","https://openalex.org/W1995976462","https://openalex.org/W1996229916","https://openalex.org/W2002397648","https://openalex.org/W2002516695","https://openalex.org/W2002903830","https://openalex.org/W2003495186","https://openalex.org/W2006459744","https://openalex.org/W2006851850","https://openalex.org/W2006964253","https://openalex.org/W2010048516","https://openalex.org/W2012079485","https://openalex.org/W2013449197","https://openalex.org/W2017035850","https://openalex.org/W2017237926","https://openalex.org/W2017727675","https://openalex.org/W2018121960","https://openalex.org/W2018282145","https://openalex.org/W2018764547","https://openalex.org/W2018843184","https://openalex.org/W2019932983","https://openalex.org/W2021630428","https://openalex.org/W2022801361","https://openalex.org/W2026404635","https://openalex.org/W2026454141","https://openalex.org/W2027121558","https://openalex.org/W2027137358","https://openalex.org/W2033503179","https://openalex.org/W2041640316","https://openalex.org/W2044030495","https://openalex.org/W2049052559","https://openalex.org/W2049285151","https://openalex.org/W2052501571","https://openalex.org/W2053607779","https://openalex.org/W2059230652","https://openalex.org/W2060516190","https://openalex.org/W2060750432","https://openalex.org/W2067568740","https://openalex.org/W2068091872","https://openalex.org/W2071901512","https://openalex.org/W2071930155","https://openalex.org/W2072345208","https://openalex.org/W2076612749","https://openalex.org/W2085492081","https://openalex.org/W2087020662","https://openalex.org/W2089597688","https://openalex.org/W2095248480","https://openalex.org/W2098692583","https://openalex.org/W2099365062","https://openalex.org/W2099525573","https://openalex.org/W2100632795","https://openalex.org/W2101501385","https://openalex.org/W2102449174","https://openalex.org/W2108200507","https://openalex.org/W2114097664","https://openalex.org/W2119724945","https://openalex.org/W2119834954","https://openalex.org/W2120225486","https://openalex.org/W2122676372","https://openalex.org/W2127215370","https://openalex.org/W2128900045","https://openalex.org/W2137664522","https://openalex.org/W2138131118","https://openalex.org/W2140366931","https://openalex.org/W2144862582","https://openalex.org/W2154964751","https://openalex.org/W2157297527","https://openalex.org/W2159527439","https://openalex.org/W2166173570","https://openalex.org/W2170678073","https://openalex.org/W2185574037","https://openalex.org/W2240800871","https://openalex.org/W2268353674","https://openalex.org/W2899801603"],"related_works":["https://openalex.org/W2053607779","https://openalex.org/W2143964656","https://openalex.org/W2620620696","https://openalex.org/W3134965860","https://openalex.org/W2089493602","https://openalex.org/W2070368404","https://openalex.org/W3197072888","https://openalex.org/W2564117926","https://openalex.org/W2626499237","https://openalex.org/W2799863411"],"abstract_inverted_index":{"Fluorinated":[0,26,127],"compounds":[1,27,54],"have":[2,28],"many":[3],"applications":[4],"in":[5,16,31,48,62,74,120,123,243],"medicine,":[6],"including":[7,119],"oxygen":[8],"transport,":[9],"drug":[10],"delivery":[11,261],"vehicles,":[12],"and":[13,23,43,122,143,166,174,187,200,210,219,237,245,278,323],"contrast":[14,33,176],"agents":[15,34],"medicine":[17],"due":[18],"to":[19,103,146,159,262,299,307,311,330],"fluorine's":[20],"unique":[21],"chemical":[22,162,201],"nuclear":[24,191],"properties.":[25],"been":[29,102],"used":[30,113,339],"microbubble":[32],"for":[35,40,88,114,168,258,267,273,344,354,375,384],"ultrasound":[36],"imaging,":[37,42,356],"positron":[38],"sources":[39],"PET":[41],"as":[44,72,137,139,170,340,371],"an":[45,73],"imaging":[46,77,90,117,277,280,373,377],"probe":[47],"19F":[49,172,198,234],"MRI.":[50],"Additionally,":[51],"fluorinated":[52,82,106,135,240],"organic":[53],"generate":[55],"a":[56,105,140,171,232,238,283,341],"high":[57,239],"ionization":[58],"yield":[59,242],"of":[60,98,133,152,265,304,313,325,368],"fluorine":[61],"secondary":[63],"ion":[64,241],"mass":[65],"spectrometry":[66],"(SIMS),":[67],"which":[68,297,357],"is":[69,364],"gaining":[70],"recognition":[71],"vitro":[75,124,316],"cellular":[76,345,360],"technique.":[78],"This":[79],"suggests":[80],"that":[81,91,110,226,249,334],"SIMS":[83,175,279,355,372],"\"chromophores\"":[84],"could":[85,111,337],"be":[86,112,338],"developed":[87,272],"diagnostic":[89,125,376],"target":[92],"specific":[93],"cell":[94,317,348,380],"markers.":[95],"The":[96,223,289],"goal":[97],"this":[99,335,385],"work":[100,363],"has":[101],"develop":[104],"nanoparticle":[107,260],"platform":[108],"technology":[109],"multiple":[115],"biomedical":[116],"techniques,":[118],"vivo":[121],"imaging.":[126,268,346],"nanoparticles":[128,227,291,328,370],"were":[129,156,180,204,212,270,292],"synthesized":[130],"from":[131],"one":[132],"two":[134],"monomers,":[136],"well":[138],"hydrophilic":[141,144],"monomer":[142],"crosslinker":[145],"enhance":[147],"the":[148,153,287,302,366,379],"aqueous":[149],"colloidal":[150,164],"stability":[151],"nanoparticles.":[154],"Nanoparticles":[155,269],"then":[157],"characterized":[158],"determine":[160],"their":[161],"properties,":[163],"stability,":[165],"suitability":[167,367],"use":[169],"MRI":[173],"agent.":[177],"Particle":[178,208],"sizes":[179],"measured":[181,196],"using":[182,197,206,215,378],"small":[183],"angle":[184],"neutron":[185],"scattering":[186],"dynamic":[188],"light":[189],"scattering,":[190],"magnetic":[192],"resonance":[193],"signal":[194,236],"was":[195,351],"NMR,":[199],"functional":[202,247],"groups":[203,248],"determined":[205],"FTIR.":[207],"size":[209],"structure":[211],"also":[213,271,352],"examined":[214],"scanning":[216],"electron":[217,221],"microscopy":[218],"transmission":[220],"microscopy.":[222],"results":[224],"suggested":[225],"are":[228],"colloidally":[229],"stable,":[230],"exhibit":[231],"strong":[233],"NMR":[235],"SIMS,":[244],"contain":[246],"would":[250],"facilitate":[251,308],"conjugation":[252],"with":[253,294],"antibodies":[254],"or":[255],"other":[256],"ligands":[257],"targeted":[259],"pathological":[263],"tissues":[264],"interest":[266],"bimodal":[274],"optical":[275],"fluorescence":[276],"by":[281],"incorporating":[282],"fluorescent":[284],"functionality":[285],"within":[286],"particles.":[288],"fluorescent-fluorinated":[290,327],"conjugated":[293],"LABL":[295],"peptide,":[296],"binds":[298],"ICAM-1":[300],"on":[301],"surface":[303],"endothelial":[305],"cells":[306],"T-cell":[309],"recruitment":[310],"sites":[312],"inflammation.":[314],"In":[315],"uptake":[318,324],"studies":[319],"show":[320],"enhanced":[321],"binding":[322],"LABL-conjugated":[326],"compared":[329],"non-conjugated":[331],"nanoparticles,":[332],"suggesting":[333],"technique":[336],"targeting":[342],"mechanism":[343],"A":[347],"preparation":[349,381],"method":[350,382],"designed":[353,383],"showed":[358],"great":[359],"detail.":[361],"Current":[362],"examining":[365],"fluorinated-fluorescent":[369],"probes":[374],"work.":[386]},"counts_by_year":[],"updated_date":"2026-09-20T07:33:13.661266","created_date":"2016-06-24T00:00:00"}
