{"id":"https://openalex.org/W1804033261","doi":"https://doi.org/10.1177/0960327114559993","title":"Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats","display_name":"Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats","publication_year":2015,"publication_date":"2015-08-18","ids":{"openalex":"https://openalex.org/W1804033261","doi":"https://doi.org/10.1177/0960327114559993","mag":"1804033261","pmid":"https://pubmed.ncbi.nlm.nih.gov/26286521"},"language":"en","primary_location":{"id":"doi:10.1177/0960327114559993","doi":"https://doi.org/10.1177/0960327114559993","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0960327114559993","pdf_url":null,"source":{"id":"https://openalex.org/S147701277","display_name":"Human & Experimental Toxicology","issn_l":"0960-3271","issn":["0960-3271","1477-0903"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human &amp; Experimental Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007777685","display_name":"H\u00fclya Elbe","orcid":"https://orcid.org/0000-0002-1254-0683","observed_orcids":["https://orcid.org/0000-0002-1254-0683"]},"institutions":[{"id":"https://openalex.org/I79946792","display_name":"Mu\u011fla University","ror":"https://ror.org/05n2cz176","country_code":"TR","type":"education","lineage":["https://openalex.org/I79946792"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"H Elbe","raw_affiliation_strings":["Department of Histology and Embryology, Faculty of Medicine, MUGLA SITKI KO\u00c7MAN UNIVERSITY, MUGLA, TURKEY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Faculty of Medicine, MUGLA SITKI KO\u00c7MAN UNIVERSITY, MUGLA, TURKEY","institution_ids":["https://openalex.org/I79946792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081694535","display_name":"Mukaddes E\u015frefo\u011flu","orcid":"https://orcid.org/0000-0003-3380-1480","observed_orcids":["https://orcid.org/0000-0003-3380-1480"]},"institutions":[{"id":"https://openalex.org/I3125175737","display_name":"Bezmi\u00e2lem Vak\u0131f \u00dcniversitesi","ror":"https://ror.org/04z60tq39","country_code":"TR","type":"education","lineage":["https://openalex.org/I3125175737"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"M Esrefoglu","raw_affiliation_strings":["Department of Histology and Embryology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey","#N# 2Department of Histology and Embryology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey","institution_ids":["https://openalex.org/I3125175737"]},{"raw_affiliation_string":"#N# 2Department of Histology and Embryology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey","institution_ids":["https://openalex.org/I3125175737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088227374","display_name":"Nigar Vard\u0131","orcid":"https://orcid.org/0000-0003-0576-1696","observed_orcids":["https://orcid.org/0000-0003-0576-1696"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"N Vardi","raw_affiliation_strings":["Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey","#N# 3Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]},{"raw_affiliation_string":"#N# 3Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033832274","display_name":"Elif Ta\u015fl\u0131dere","orcid":"https://orcid.org/0000-0003-1723-2556","observed_orcids":["https://orcid.org/0000-0003-1723-2556"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"E Taslidere","raw_affiliation_strings":["Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey","#N# 3Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]},{"raw_affiliation_string":"#N# 3Department of Histology and Embryology, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047611762","display_name":"Elif \u00d6zerol","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"E Ozerol","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey","#N#4Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]},{"raw_affiliation_string":"#N#4Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089613482","display_name":"Kevser Tanbek","orcid":"https://orcid.org/0000-0003-2099-2273","observed_orcids":["https://orcid.org/0000-0003-2099-2273"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"K Tanbek","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey","#N#4Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]},{"raw_affiliation_string":"#N#4Department of Biochemistry, Faculty of Medicine, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5007777685"],"corresponding_institution_ids":["https://openalex.org/I79946792"],"apc_list":{"value":2800,"currency":"USD","value_usd":2800},"apc_paid":null,"fwci":4.4358,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.95047248,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"34","issue":"9","first_page":"859","last_page":"868"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.01759999990463257,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11051","display_name":"Sirtuins and Resveratrol in Medicine","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/quercetin","display_name":"quercetin","score":1.0},{"id":"https://openalex.org/keywords/resveratrol","display_name":"resveratrol","score":1.0},{"id":"https://openalex.org/keywords/hepatocyte-injury","display_name":"hepatocyte injury","score":0.6819999814033508},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9810000061988831},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9160000085830688},{"id":"https://openalex.org/keywords/liver-histopathology","display_name":"liver histopathology","score":0.7139999866485596},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.8379999995231628},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.9399999976158142},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9919999837875366},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.9909999966621399},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.32199999690055847}],"concepts":[{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.8325150012969971},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.8068912625312805},{"id":"https://openalex.org/C2776816829","wikidata":"https://www.wikidata.org/wiki/Q407329","display_name":"Resveratrol","level":2,"score":0.7503664493560791},{"id":"https://openalex.org/C2781263971","wikidata":"https://www.wikidata.org/wiki/Q409478","display_name":"Quercetin","level":3,"score":0.6452113389968872},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.6155178546905518},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5658011436462402},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.484208345413208},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4440465271472931},{"id":"https://openalex.org/C3020296196","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative damage","level":3,"score":0.4398390054702759},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4344240427017212},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.41593942046165466},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4142273962497711},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3347223997116089},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.31969648599624634},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1406061351299286}],"mesh":[{"descriptor_ui":"D000077185","descriptor_name":"Resveratrol","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002374","descriptor_name":"Catalase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003921","descriptor_name":"Diabetes Mellitus, Experimental","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006505","descriptor_name":"Hepatitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006505","descriptor_name":"Hepatitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006505","descriptor_name":"Hepatitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008550","descriptor_name":"Melatonin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011794","descriptor_name":"Quercetin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013267","descriptor_name":"Stilbenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013482","descriptor_name":"Superoxide Dismutase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D022781","descriptor_name":"Hepatocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D022781","descriptor_name":"Hepatocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D048909","descriptor_name":"Diabetes Complications","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D048909","descriptor_name":"Diabetes Complications","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1177/0960327114559993","doi":"https://doi.org/10.1177/0960327114559993","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0960327114559993","pdf_url":null,"source":{"id":"https://openalex.org/S147701277","display_name":"Human & Experimental Toxicology","issn_l":"0960-3271","issn":["0960-3271","1477-0903"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human &amp; Experimental Toxicology","raw_type":"journal-article"},{"id":"pmid:26286521","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26286521","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human & experimental toxicology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W101694538","https://openalex.org/W969915667","https://openalex.org/W1544034054","https://openalex.org/W1566664111","https://openalex.org/W1566830427","https://openalex.org/W1775749144","https://openalex.org/W1965515658","https://openalex.org/W1966482673","https://openalex.org/W1977903439","https://openalex.org/W1979114643","https://openalex.org/W1981113781","https://openalex.org/W1983621094","https://openalex.org/W1984979932","https://openalex.org/W1985743555","https://openalex.org/W1988077890","https://openalex.org/W1993796792","https://openalex.org/W2000118672","https://openalex.org/W2000677749","https://openalex.org/W2004953987","https://openalex.org/W2006370393","https://openalex.org/W2011117661","https://openalex.org/W2015528930","https://openalex.org/W2016847030","https://openalex.org/W2018185635","https://openalex.org/W2025353298","https://openalex.org/W2032561678","https://openalex.org/W2034689719","https://openalex.org/W2042810345","https://openalex.org/W2052811641","https://openalex.org/W2055869768","https://openalex.org/W2057662918","https://openalex.org/W2072391640","https://openalex.org/W2085500476","https://openalex.org/W2090095746","https://openalex.org/W2092033707","https://openalex.org/W2105388269","https://openalex.org/W2106706630","https://openalex.org/W2111515434","https://openalex.org/W2121786223","https://openalex.org/W2125278030","https://openalex.org/W2132796902","https://openalex.org/W2136922901","https://openalex.org/W2151274898","https://openalex.org/W2156068394","https://openalex.org/W2156573785","https://openalex.org/W2159305277","https://openalex.org/W2160793932","https://openalex.org/W2167226448","https://openalex.org/W2171329364","https://openalex.org/W2172206387","https://openalex.org/W2184946984","https://openalex.org/W2258362203","https://openalex.org/W2313559825","https://openalex.org/W2409648023","https://openalex.org/W2940627724","https://openalex.org/W4205407119","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2111515434","https://openalex.org/W2125278030","https://openalex.org/W2156068394","https://openalex.org/W2042073463","https://openalex.org/W1972450434","https://openalex.org/W7155411869","https://openalex.org/W2895327082","https://openalex.org/W1965659213","https://openalex.org/W2464025567","https://openalex.org/W2953795434"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"effects":[3],"of":[4,79,127,135,177],"melatonin,":[5],"quercetin":[6,53,207,234],"and":[7,24,57,65,70,96,102,106,110,160,194,197,208,219,222,235],"resveratrol":[8,60,209,236],"on":[9],"hepatocellular":[10,240],"injury":[11,241],"in":[12,164,175,202,216,225,242],"streptozotocin":[13],"(STZ)-induced":[14],"experimental":[15,244],"diabetes":[16,39,45,51,58,165,204],"were":[17,32,74,88,114,138,162,200],"aimed":[18],"to":[19],"be":[20],"investigated":[21],"by":[22],"histological":[23],"biochemical":[25],"methods.":[26],"Thirty-five":[27],"male":[28],"Wistar":[29],"albino":[30],"rats":[31,118,129,137,146,212],"divided":[33],"into":[34],"five":[35],"groups,":[36],"namely,":[37],"control,":[38],"(STZ":[40],"45":[41],"mg/kg/single":[42],"dose/intraperitoneally":[43],"(ip)),":[44],"+":[46,52,59],"melatonin":[47],"(10":[48,61],"mg/kg/30":[49,55,62],"days/ip),":[50],"(25":[54],"days/ip)":[56],"days/ip).":[63],"Initial":[64],"final":[66],"blood":[67,122],"glucose":[68,123],"levels":[69,105,124,199,221,227],"body":[71],"weights":[72],"(BWs)":[73],"measured.":[75],"At":[76],"the":[77,80,144,168,178,203],"end":[78],"experimentation,":[81],"following":[82],"routine":[83],"tissue":[84,185,192],"processing":[85],"procedure,":[86],"sections":[87],"stained":[89],"with":[90,143],"haematoxylin-eosin":[91],"(H-E),":[92],"periodic":[93],"acid":[94],"Schiff":[95],"Masson's":[97],"trichrome.":[98],"Tissue":[99],"malondialdehyde":[100],"(MDA)":[101],"glutathione":[103],"(GSH)":[104],"superoxide":[107],"dismutase":[108],"(SOD)":[109],"catalase":[111],"(CAT)":[112],"activities":[113,196,218],"examined.":[115],"The":[116],"diabetic":[117,136,211],"had":[119],"significantly":[120,139],"higher":[121],"than":[125],"those":[126],"control":[128,145],"(p":[130,147,181,228],"=":[131,148,182],"0.0001).":[132],"Mean":[133,184],"BWs":[134],"decreased":[140,201],"when":[141],"compared":[142],"0.0013).":[149],"Histopathological":[150],"alterations":[151],"including":[152],"cellular":[153],"glycogen":[154],"depletion,":[155],"congestion,":[156],"sinusoidal":[157],"dilatation,":[158],"inflammation":[159],"fibrosis":[161],"detected":[163],"group.":[166,205],"On":[167],"other":[169],"hand,":[170],"histopathological":[171],"changes":[172],"markedly":[173,238],"reduced":[174,239],"all":[176],"treatment":[179],"groups":[180],"0.001).":[183],"MDA":[186,226],"level":[187],"was":[188],"increased":[189],"but":[190],"mean":[191],"CAT":[193,217],"SOD":[195],"GSH":[198,220],"Melatonin,":[206,233],"administered":[210],"showed":[213],"an":[214],"increase":[215],"a":[223],"decrease":[224],"<":[229],"0.05,":[230],"for":[231],"all).":[232],"administrations":[237],"STZ-induced":[243],"diabetes.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}