{"id":"https://openalex.org/W1785408208","doi":"https://doi.org/10.1016/s0016-5085(11)62633-4","title":"Clostridium difficile Strains of Human and Veterinary Origin Attach Efficiently to Human Intestinal Epithelial Cells via the Major Surface-Layer Protein Slpa","display_name":"Clostridium difficile Strains of Human and Veterinary Origin Attach Efficiently to Human Intestinal Epithelial Cells via the Major Surface-Layer Protein Slpa","publication_year":2011,"publication_date":"2011-05-01","ids":{"openalex":"https://openalex.org/W1785408208","doi":"https://doi.org/10.1016/s0016-5085(11)62633-4","mag":"1785408208"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(11)62633-4","doi":"https://doi.org/10.1016/s0016-5085(11)62633-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(11)62633-4","pdf_url":"https://doi.org/10.1016/s0016-5085(11)62633-4","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0016-5085(11)62633-4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033243316","display_name":"Michelle M. Merrigan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michelle Merrigan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090530319","display_name":"Anilrudh A. Venugopal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anilrudh Venugopal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047402283","display_name":"Jennifer Lising Roxas","orcid":"https://orcid.org/0000-0002-6276-9208","observed_orcids":["https://orcid.org/0000-0002-6276-9208"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer L. Roxas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043937432","display_name":"Christopher M. Wiethoff","orcid":"https://orcid.org/0000-0001-9102-7492","observed_orcids":["https://orcid.org/0000-0001-9102-7492"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christopher M. Wiethoff","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020885197","display_name":"Glenn Songer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Glenn Songer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018192461","display_name":"Neil F. Fairweather","orcid":"https://orcid.org/0000-0002-3224-0207","observed_orcids":["https://orcid.org/0000-0002-3224-0207"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neil Fairweather","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019164833","display_name":"V. K. Viswanathan","orcid":"https://orcid.org/0000-0002-9258-9865","observed_orcids":["https://orcid.org/0000-0002-9258-9865"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V.K. Viswanathan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5017921517","display_name":"Gayatri Vedantam","orcid":"https://orcid.org/0000-0002-3144-0610","observed_orcids":["https://orcid.org/0000-0002-3144-0610"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gayatri Vedantam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08391629,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"140","issue":"5","first_page":"S","last_page":"636"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clostridioides-difficile","display_name":"Clostridium difficile","score":1.0},{"id":"https://openalex.org/keywords/slpa","display_name":"SlpA","score":0.8579999804496765},{"id":"https://openalex.org/keywords/bacterial-adhesion","display_name":"bacterial adhesion","score":0.8450000286102295},{"id":"https://openalex.org/keywords/intestinal-epithelial-cells","display_name":"intestinal epithelial cells","score":0.9549999833106995},{"id":"https://openalex.org/keywords/human-strains","display_name":"human strains","score":0.37599998712539673},{"id":"https://openalex.org/keywords/host-specificity","display_name":"host specificity","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C2994496256","wikidata":"https://www.wikidata.org/wiki/Q27031090","display_name":"Clostridium difficile","level":3,"score":0.749801754951477},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7170971632003784},{"id":"https://openalex.org/C2781092032","wikidata":"https://www.wikidata.org/wiki/Q327663","display_name":"Clostridium","level":3,"score":0.49941587448120117},{"id":"https://openalex.org/C114883478","wikidata":"https://www.wikidata.org/wiki/Q418821","display_name":"S-layer","level":3,"score":0.41200560331344604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32882028818130493},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2973804473876953},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.06187036633491516},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(11)62633-4","doi":"https://doi.org/10.1016/s0016-5085(11)62633-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(11)62633-4","pdf_url":"https://doi.org/10.1016/s0016-5085(11)62633-4","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s0016-5085(11)62633-4","doi":"https://doi.org/10.1016/s0016-5085(11)62633-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(11)62633-4","pdf_url":"https://doi.org/10.1016/s0016-5085(11)62633-4","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":true},"content_urls":{"grobid_xml":"https://content.openalex.org/works/W1785408208.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2138517547","https://openalex.org/W2027550017","https://openalex.org/W2171148052","https://openalex.org/W6980595438","https://openalex.org/W2883152742","https://openalex.org/W1565359585","https://openalex.org/W2788942005","https://openalex.org/W1173175892","https://openalex.org/W2135801144","https://openalex.org/W4396676510"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}