{"id":"https://openalex.org/W1783301488","doi":"https://doi.org/10.1164/ajrccm.156.4.9610104","title":"Exogenous Surfactant and Partial Liquid Ventilation","display_name":"Exogenous Surfactant and Partial Liquid Ventilation","publication_year":1997,"publication_date":"1997-10-01","ids":{"openalex":"https://openalex.org/W1783301488","doi":"https://doi.org/10.1164/ajrccm.156.4.9610104","mag":"1783301488","pmid":"https://pubmed.ncbi.nlm.nih.gov/9351603"},"language":"en","primary_location":{"id":"doi:10.1164/ajrccm.156.4.9610104","doi":"https://doi.org/10.1164/ajrccm.156.4.9610104","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm.156.4.9610104","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Respiratory and Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022222243","display_name":"Jeanne D. Mrozek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JEANNE D. MROZEK","raw_affiliation_strings":["Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036607419","display_name":"Kendra M. Smith","orcid":"https://orcid.org/0000-0002-4316-1280","observed_orcids":["https://orcid.org/0000-0002-4316-1280"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"KENDRA M. SMITH","raw_affiliation_strings":["Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109867979","display_name":"Dennis R. Bing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"DENNIS R. BING","raw_affiliation_strings":["Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109923751","display_name":"Pat A. Meyers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"PAT A. MEYERS","raw_affiliation_strings":["Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019645667","display_name":"Susan C. Simonton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"SUSAN C. SIMONTON","raw_affiliation_strings":["Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089798726","display_name":"John E. Connett","orcid":"https://orcid.org/0000-0002-8149-9709","observed_orcids":["https://orcid.org/0000-0002-8149-9709"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JOHN E. CONNETT","raw_affiliation_strings":["Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008961864","display_name":"Mark C. Mammel","orcid":"https://orcid.org/0000-0002-2256-4574","observed_orcids":["https://orcid.org/0000-0002-2256-4574"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MARK C. MAMMEL","raw_affiliation_strings":["Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infant Pulmonary Research Center, Children's Health Care\u2013St. Paul, St. Paul; and Departments of Pediatrics and Biostatistics, University of Minnesota, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I130238516"],"apc_list":null,"apc_paid":null,"fwci":6.98,"has_fulltext":false,"cited_by_count":121,"citation_normalized_percentile":{"value":0.96850161,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"156","issue":"4","first_page":"1058","last_page":"1065"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.8413000106811523,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.8413000106811523,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.15639999508857727,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exogenous-surfactant","display_name":"exogenous surfactant","score":0.9150000214576721},{"id":"https://openalex.org/keywords/partial-liquid-ventilation","display_name":"partial liquid ventilation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/administration-order","display_name":"administration order","score":0.7820000052452087},{"id":"https://openalex.org/keywords/oxygenation","display_name":"oxygenation","score":0.5379999876022339},{"id":"https://openalex.org/keywords/respiratory-system-compliance","display_name":"respiratory compliance","score":0.9700000286102295},{"id":"https://openalex.org/keywords/hemodynamics","display_name":"hemodynamics","score":0.8980000019073486},{"id":"https://openalex.org/keywords/lung-injury","display_name":"lung injury","score":0.9419999718666077},{"id":"https://openalex.org/keywords/pulmonary-pathology","display_name":"lung pathology","score":0.5419999957084656},{"id":"https://openalex.org/keywords/oxygenation-index","display_name":"oxygenation index","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.8693047761917114},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.733079731464386},{"id":"https://openalex.org/C70289976","wikidata":"https://www.wikidata.org/wiki/Q17143603","display_name":"Oxygenation","level":2,"score":0.6578460931777954},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.5961218476295471},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.5536240935325623},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5236958265304565},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4932019114494324},{"id":"https://openalex.org/C136936797","wikidata":"https://www.wikidata.org/wiki/Q2990558","display_name":"Pulmonary compliance","level":3,"score":0.48814234137535095},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.44948631525039673},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2682231366634369},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13001355528831482},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.03919079899787903},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001784","descriptor_name":"Blood Gas Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003187","descriptor_name":"Compliance","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005466","descriptor_name":"Fluorocarbons","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008171","descriptor_name":"Lung Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008171","descriptor_name":"Lung Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008171","descriptor_name":"Lung Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011659","descriptor_name":"Pulmonary Gas Exchange","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011663","descriptor_name":"Pulmonary Surfactants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015656","descriptor_name":"Respiratory Mechanics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D055370","descriptor_name":"Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1164/ajrccm.156.4.9610104","doi":"https://doi.org/10.1164/ajrccm.156.4.9610104","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm.156.4.9610104","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Respiratory and Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:9351603","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9351603","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of respiratory and critical care medicine","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.337.4184","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.337.4184","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ajrccm.atsjournals.org/content/156/4/1058.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W167775893","https://openalex.org/W1930000548","https://openalex.org/W1969480274","https://openalex.org/W1970802958","https://openalex.org/W1973531791","https://openalex.org/W1976735411","https://openalex.org/W1984963960","https://openalex.org/W1986833152","https://openalex.org/W1995488303","https://openalex.org/W1996819436","https://openalex.org/W2002154330","https://openalex.org/W2017249554","https://openalex.org/W2023409676","https://openalex.org/W2027770755","https://openalex.org/W2036389865","https://openalex.org/W2039142333","https://openalex.org/W2039678890","https://openalex.org/W2047946449","https://openalex.org/W2049480582","https://openalex.org/W2052464600","https://openalex.org/W2053207698","https://openalex.org/W2057636301","https://openalex.org/W2067594941","https://openalex.org/W2075725232","https://openalex.org/W2076882106","https://openalex.org/W2087618949","https://openalex.org/W2092521929","https://openalex.org/W2096134044","https://openalex.org/W2102159106","https://openalex.org/W2127719919","https://openalex.org/W2229248990","https://openalex.org/W2332939473","https://openalex.org/W2339007256","https://openalex.org/W2416035168","https://openalex.org/W4232548876","https://openalex.org/W4237774867"],"related_works":["https://openalex.org/W2052786722","https://openalex.org/W1976229978","https://openalex.org/W6995692398","https://openalex.org/W2578177799","https://openalex.org/W7070650901","https://openalex.org/W1972429299","https://openalex.org/W2002637037","https://openalex.org/W2022107664","https://openalex.org/W2035596825","https://openalex.org/W2274222728"],"abstract_inverted_index":{"We":[0,33,114,200],"compared":[1,189],"the":[2,12,191,194,239],"effects":[3],"of":[4,14,177,185,193],"surfactant":[5,37,51,66,119,128,142,203,222,234],"and":[6,11,24,61,80,149,181,214,231],"partial":[7,43,54,62],"liquid":[8,44,55,63],"ventilation":[9,45,56],"(PLV),":[10],"impact":[13],"administration":[15],"order,":[16],"on":[17],"oxygenation,":[18,210],"respiratory":[19,211],"system":[20,212],"compliance":[21],"(Crs),":[22],"hemodynamics,":[23],"lung":[25,30,172,215],"pathology":[26,216],"in":[27,83,174,182,205,242],"an":[28],"animal":[29],"injury":[31,173],"model.":[32],"studied":[34],"four":[35],"groups:":[36],"alone":[38,46],"(S;":[39],"n":[40,48,58,68],"=":[41,49,59,69],"8);":[42,50,60],"(PLV-only;":[47],"followed":[52],"by":[53,65],"(S-PLV;":[57],"ventilation-followed":[64],"(PLV-S;":[67],"8).":[70],"Following":[71],"treatments,":[72],"all":[73,178,183],"animals":[74,196],"had":[75],"improved":[76,122,209],"oxygenation":[77],"index":[78],"(OI)":[79],"Crs.":[81],"Animals":[82],"PLV":[84,121,144,154,208,237],"groups":[85],"showed":[86],"continued":[87],"improvement":[88],"over":[89],"2":[90],"h":[91],"(%":[92],"change":[93,104,147],"OI:":[94],"PLV-S":[95],"-83%":[96],"versus":[97,108,129,155],"S":[98,109,195],"-47%,":[99],"p":[100,111,135,159],"<":[101,112,136,160,198],"0.05;":[102],"%":[103],"Crs:":[105],"S-PLV":[106,186],"73%":[107],"13%,":[110],"0.05).":[113,199],"also":[115],"saw":[116],"administration-order":[117],"effects:":[118],"before":[120,236],"Crs":[123,148],"(0.92":[124],"ml/cm":[125,131],"H2O":[126,132],"after":[127,133,143,153,157],"1.13":[130],"PLV,":[134],"0.02)":[137],"without":[138],"changing":[139],"OI,":[140],"whereas":[141],"did":[145],"not":[146,164],"OI":[150],"increased":[151],"(5.01":[152],"8.92":[156],"surfactant,":[158],"0.03).":[161],"Hemodynamics":[162],"were":[163],"different":[165],"between":[166],"groups.":[167],"Pathologic":[168],"analysis":[169],"demonstrated":[170],"decreased":[171],"dependent":[175],"lobes":[176,184,192],"PLV-treated":[179],"animals,":[180,187],"when":[188],"with":[190,207],"(p":[197],"conclude":[201],"that":[202],"therapy":[204,223],"combination":[206],"mechanics,":[213],"to":[217],"a":[218],"greater":[219],"degree":[220],"than":[221],"alone.":[224],"Administration":[225],"order":[226],"affected":[227],"initial":[228],"physiologic":[229],"response":[230],"ultimate":[232],"pathology:":[233],"given":[235],"produced":[238],"greatest":[240],"improvements":[241],"pathologic":[243],"outcomes.":[244]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}