{"id":"https://openalex.org/W1783028201","doi":"https://doi.org/10.1016/s0079-6603(08)60053-7","title":"Mutational Spectrometry: Means and Ends","display_name":"Mutational Spectrometry: Means and Ends","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W1783028201","doi":"https://doi.org/10.1016/s0079-6603(08)60053-7","mag":"1783028201","pmid":"https://pubmed.ncbi.nlm.nih.gov/7863009"},"language":"en","primary_location":{"id":"doi:10.1016/s0079-6603(08)60053-7","doi":"https://doi.org/10.1016/s0079-6603(08)60053-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0079-6603(08)60053-7","pdf_url":null,"source":{"id":"https://openalex.org/S65792589","display_name":"Progress in nucleic acid research and molecular biology","issn_l":"0079-6603","issn":["0079-6603","2211-9108"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Nucleic Acid Research and Molecular Biology","raw_type":"book-chapter"},"volume":null,"type":"book-chapter","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007809456","display_name":"Konstantin Khrapko","orcid":"https://orcid.org/0000-0002-9250-8033","observed_orcids":["https://orcid.org/0000-0002-9250-8033"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. Khrapko","raw_affiliation_strings":["Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. Andr\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Andr\u00e9","raw_affiliation_strings":["Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":null,"display_name":"R. Cha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Cha","raw_affiliation_strings":["Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029984124","display_name":"Geng Hu","orcid":"https://orcid.org/0000-0003-3914-6261","observed_orcids":["https://orcid.org/0000-0003-3914-6261"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Hu","raw_affiliation_strings":["Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049356247","display_name":"William G. Thilly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"W.G. Thilly","raw_affiliation_strings":["Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049356247"],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":null,"apc_paid":null,"fwci":3.3043,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.93285372,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"49","issue":null,"first_page":"285","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.022299999371170998,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mutational-spectra","display_name":"mutational spectra","score":0.8870000243186951},{"id":"https://openalex.org/keywords/point-mutations","display_name":"point mutations","score":0.6470000147819519},{"id":"https://openalex.org/keywords/mutagenesis","display_name":"mutagenesis","score":0.6830000281333923},{"id":"https://openalex.org/keywords/spontaneous-mutation","display_name":"spontaneous mutation","score":0.7099999785423279},{"id":"https://openalex.org/keywords/chemically-induced-mutations","display_name":"chemically induced mutations","score":0.9210000038146973}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7244478464126587},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.61009281873703},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.6069836020469666},{"id":"https://openalex.org/C4839761","wikidata":"https://www.wikidata.org/wiki/Q212111","display_name":"Spectral line","level":2,"score":0.5903034806251526},{"id":"https://openalex.org/C151201525","wikidata":"https://www.wikidata.org/wiki/Q177239","display_name":"Limit (mathematics)","level":2,"score":0.55678790807724},{"id":"https://openalex.org/C2776441376","wikidata":"https://www.wikidata.org/wiki/Q165028","display_name":"Bacteriophage","level":4,"score":0.5312623381614685},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.49441051483154297},{"id":"https://openalex.org/C176944494","wikidata":"https://www.wikidata.org/wiki/Q1415380","display_name":"Point mutation","level":4,"score":0.49194952845573425},{"id":"https://openalex.org/C2778113609","wikidata":"https://www.wikidata.org/wiki/Q10897","display_name":"Lambda","level":2,"score":0.4416981637477875},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34797728061676025},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3295975923538208},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.23896396160125732},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.13125386834144592},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1177067756652832},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10186120867729187},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.06530621647834778},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009691","descriptor_name":"Nucleic Acid Denaturation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012150","descriptor_name":"Polymorphism, Restriction Fragment Length","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0079-6603(08)60053-7","doi":"https://doi.org/10.1016/s0079-6603(08)60053-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0079-6603(08)60053-7","pdf_url":null,"source":{"id":"https://openalex.org/S65792589","display_name":"Progress in nucleic acid research and molecular biology","issn_l":"0079-6603","issn":["0079-6603","2211-9108"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Nucleic Acid Research and Molecular Biology","raw_type":"book-chapter"},{"id":"pmid:7863009","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7863009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in nucleic acid research and molecular biology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W141489584","https://openalex.org/W284266145","https://openalex.org/W1512997946","https://openalex.org/W1539849827","https://openalex.org/W1555039120","https://openalex.org/W1571168065","https://openalex.org/W1576596365","https://openalex.org/W1585201985","https://openalex.org/W1968952472","https://openalex.org/W1970174166","https://openalex.org/W1971199253","https://openalex.org/W1978208924","https://openalex.org/W1979388953","https://openalex.org/W1987389293","https://openalex.org/W1987802717","https://openalex.org/W1988983348","https://openalex.org/W1990580218","https://openalex.org/W1990896124","https://openalex.org/W1991131571","https://openalex.org/W1993621531","https://openalex.org/W2012210882","https://openalex.org/W2013985234","https://openalex.org/W2018303534","https://openalex.org/W2021225519","https://openalex.org/W2021328324","https://openalex.org/W2023238422","https://openalex.org/W2030637796","https://openalex.org/W2031297529","https://openalex.org/W2033089306","https://openalex.org/W2036798876","https://openalex.org/W2041963065","https://openalex.org/W2042282283","https://openalex.org/W2043371191","https://openalex.org/W2046958814","https://openalex.org/W2048339025","https://openalex.org/W2048944293","https://openalex.org/W2050682329","https://openalex.org/W2050717506","https://openalex.org/W2053631253","https://openalex.org/W2055026289","https://openalex.org/W2058093686","https://openalex.org/W2063734729","https://openalex.org/W2064063117","https://openalex.org/W2064504648","https://openalex.org/W2068568687","https://openalex.org/W2077275925","https://openalex.org/W2096715388","https://openalex.org/W2097632362","https://openalex.org/W2147184989","https://openalex.org/W2172960123","https://openalex.org/W2276572970","https://openalex.org/W2394603733","https://openalex.org/W2982996672"],"related_works":["https://openalex.org/W1980438542","https://openalex.org/W2137189848","https://openalex.org/W2030417731","https://openalex.org/W2029796352","https://openalex.org/W1042073485","https://openalex.org/W2119360901","https://openalex.org/W1985434600","https://openalex.org/W175031529","https://openalex.org/W4210440584","https://openalex.org/W2156972793"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
