{"id":"https://openalex.org/W176921772","doi":null,"title":"Diabetes in old age: an emerging epidemic.","display_name":"Diabetes in old age: an emerging epidemic.","publication_year":2003,"publication_date":"2003-11-01","ids":{"openalex":"https://openalex.org/W176921772","mag":"176921772","pmid":"https://pubmed.ncbi.nlm.nih.gov/15260395"},"language":"en","primary_location":{"id":"pmid:15260395","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15260395","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of the Association of Physicians of India","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000810103","display_name":"Jothydev Kesavadev","orcid":"https://orcid.org/0000-0001-6522-6391","observed_orcids":["https://orcid.org/0000-0001-6522-6391"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J D Kesavadev","raw_affiliation_strings":["Indian Institute of Diabetes, Pulayanarkotta, Trivandrum, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Diabetes, Pulayanarkotta, Trivandrum, Kerala, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069827652","display_name":"Kevin R. Short","orcid":"https://orcid.org/0000-0001-6704-9587","observed_orcids":["https://orcid.org/0000-0001-6704-9587"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K R Short","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5002287349","display_name":"K. Sreekumaran Nair","orcid":"https://orcid.org/0000-0002-0649-9469","observed_orcids":["https://orcid.org/0000-0002-0649-9469"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Sreekumaran Nair","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7744,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.73039185,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"51","issue":null,"first_page":"1083","last_page":"94"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.039799999445676804,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetes-in-the-elderly","display_name":"elderly diabetes","score":0.8650000095367432},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.6340000033378601},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7680000066757202},{"id":"https://openalex.org/keywords/abdominal-obesity","display_name":"abdominal obesity","score":0.7260000109672546},{"id":"https://openalex.org/keywords/sarcopenia","display_name":"sarcopenia","score":0.7910000085830688},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.46299999952316284},{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.8309999704360962},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.796999990940094},{"id":"https://openalex.org/keywords/postprandial-hyperglycemia","display_name":"postprandial hyperglycemia","score":0.949999988079071},{"id":"https://openalex.org/keywords/antidiabetic-drugs","display_name":"antidiabetic drugs","score":0.8759999871253967},{"id":"https://openalex.org/keywords/diabetes-complications","display_name":"diabetes complications","score":0.6809999942779541},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.44600000977516174},{"id":"https://openalex.org/keywords/hyperlipidemia","display_name":"hyperlipidemia","score":0.9789999723434448}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9017754793167114},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7620555758476257},{"id":"https://openalex.org/C2778199505","wikidata":"https://www.wikidata.org/wiki/Q2992990","display_name":"Postprandial","level":3,"score":0.6729457378387451},{"id":"https://openalex.org/C133925201","wikidata":"https://www.wikidata.org/wiki/Q188419","display_name":"Life expectancy","level":3,"score":0.5192282795906067},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.49924302101135254},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.45078200101852417},{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.43825921416282654},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.43536412715911865},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.42849284410476685},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.4194614589214325},{"id":"https://openalex.org/C2776214593","wikidata":"https://www.wikidata.org/wiki/Q1787939","display_name":"Sarcopenia","level":2,"score":0.4181599020957947},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26619088649749756},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.21369317173957825},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.17053267359733582}],"mesh":[{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010353","descriptor_name":"Patient Education as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014943","descriptor_name":"Global Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:15260395","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15260395","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of the Association of Physicians of India","raw_type":"Journal Article"},{"id":"mag:176921772","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15260395","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3951293336","display_name":"Mechanism of Muscle Wasting in Aging Man","funder_award_id":"R01AG009531","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5918705860","display_name":"General Clinical Research Center","funder_award_id":"M01RR000585","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G7608927542","display_name":"In Vivo Regulation of Protein Turnover by Hormones","funder_award_id":"R01DK041973","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W62605065","https://openalex.org/W63541796","https://openalex.org/W177601770","https://openalex.org/W1892420199","https://openalex.org/W1920052608","https://openalex.org/W1966078541","https://openalex.org/W1968876389","https://openalex.org/W1968989744","https://openalex.org/W1973551179","https://openalex.org/W1973842058","https://openalex.org/W1974242043","https://openalex.org/W1994745382","https://openalex.org/W1996517131","https://openalex.org/W1997295514","https://openalex.org/W2005880517","https://openalex.org/W2016431637","https://openalex.org/W2017932174","https://openalex.org/W2019011670","https://openalex.org/W2020961569","https://openalex.org/W2022038915","https://openalex.org/W2022796086","https://openalex.org/W2031484324","https://openalex.org/W2031831221","https://openalex.org/W2039173197","https://openalex.org/W2041609517","https://openalex.org/W2047397124","https://openalex.org/W2055726169","https://openalex.org/W2055841488","https://openalex.org/W2059130580","https://openalex.org/W2059804586","https://openalex.org/W2064405202","https://openalex.org/W2075526503","https://openalex.org/W2076585242","https://openalex.org/W2091232091","https://openalex.org/W2095224404","https://openalex.org/W2099578939","https://openalex.org/W2102013773","https://openalex.org/W2105516210","https://openalex.org/W2112834655","https://openalex.org/W2114514509","https://openalex.org/W2121206285","https://openalex.org/W2122857181","https://openalex.org/W2123106337","https://openalex.org/W2126270145","https://openalex.org/W2129714705","https://openalex.org/W2130864096","https://openalex.org/W2132665092","https://openalex.org/W2140937253","https://openalex.org/W2142454930","https://openalex.org/W2145678519","https://openalex.org/W2156121263","https://openalex.org/W2158020687","https://openalex.org/W2160164021","https://openalex.org/W2163278326","https://openalex.org/W2164514768","https://openalex.org/W2167818045","https://openalex.org/W2241881866","https://openalex.org/W2321207895","https://openalex.org/W2334072750","https://openalex.org/W2337454357","https://openalex.org/W2399422809","https://openalex.org/W2399970159","https://openalex.org/W2409497214","https://openalex.org/W2412665692","https://openalex.org/W2416392267","https://openalex.org/W2417078107","https://openalex.org/W2419546265","https://openalex.org/W2607778979","https://openalex.org/W4239471829","https://openalex.org/W4255885452"],"related_works":["https://openalex.org/W2411119852","https://openalex.org/W2921236584","https://openalex.org/W2339639987","https://openalex.org/W1997125058","https://openalex.org/W2416377063","https://openalex.org/W2091422900","https://openalex.org/W2411380598","https://openalex.org/W2004326755","https://openalex.org/W2400840926","https://openalex.org/W3168479043"],"abstract_inverted_index":{"Diabetes":[0],"in":[1,29,44,59,66,73,78,93,105,114,139,153,176,204,208,214,222,228,235],"the":[2,9,16,22,30,40,45,67,74,79,177,209,223,229,236,243,246],"elderly":[3,178,205,237],"is":[4,48,69,148,198],"emerging":[5],"as":[6],"one":[7],"of":[8,15,24,33,42,64,76,86,130,174,225,232,245,252,269,274,278],"most":[10],"important":[11],"public":[12],"health":[13],"problems":[14],"21st":[17],"century.":[18],"In":[19],"developing":[20],"countries,":[21],"majority":[23],"people":[25,160,206],"with":[26,62],"diabetes":[27,43,77,175,203,233],"are":[28,259,282],"age":[31,244],"range":[32],"45-64":[34],"years.":[35],"A":[36],"better":[37],"understanding":[38],"on":[39],"pathogenesis":[41],"aging":[46,80],"population":[47],"required":[49],"to":[50,99,111,151,162,166,201,239,261,284],"successfully":[51],"treat":[52],"and":[53,84,102,117,141,172,187,217,250,264,280],"prevent":[54,285],"its":[55],"devastating":[56],"complications.":[57,286],"Changes":[58],"body":[60,185,215],"composition":[61,186],"accumulation":[63,120],"fat":[65,119],"abdomen":[68],"a":[70,89,103],"key":[71],"factor":[72],"causation":[75],"population.":[81],"The":[82],"size":[83],"strength":[85],"skeletal":[87],"muscle,":[88],"major":[90],"tissue":[91],"involved":[92],"glucose":[94],"metabolism,":[95],"also":[96],"declines":[97],"leading":[98],"muscle":[100,135],"weakness":[101],"reduction":[104,113],"physical":[106],"activity.":[107],"These":[108],"changes":[109,213],"lead":[110],"marked":[112],"energy":[115],"expenditure":[116],"abdominal":[118],"causing":[121],"insulin":[122,146,169,257,270],"resistance.":[123],"Recent":[124],"evidence":[125,193],"suggests":[126,194],"that":[127,145,158,195],"four":[128],"months":[129],"aerobic":[131],"exercise":[132,163],"can":[133],"improve":[134,152,167],"oxidative":[136],"capacity":[137],"similarly":[138],"younger":[140],"older":[142,154,159],"people,":[143],"but":[144],"sensitivity":[147],"less":[149],"likely":[150],"people.":[155],"It":[156],"appears":[157],"need":[161],"more":[164,199],"frequently":[165],"their":[168],"sensitivity.":[170],"Diagnosis":[171],"management":[173],"requires":[179],"special":[180,220],"attention":[181],"since":[182],"age,":[183],"genetics,":[184],"lifestyle":[188],"factors":[189],"all":[190],"interact.":[191],"Increasing":[192],"postprandial":[196],"hyperglycemia":[197],"sensitive":[200],"diagnose":[202],"than":[207],"young.":[210],"Age":[211],"related":[212],"function":[216],"cognition":[218],"demand":[219],"caution":[221],"selection":[224],"hypoglycemic":[226],"drugs":[227],"elderly.":[230],"Targets":[231],"therapy":[234],"have":[238],"be":[240],"individualized,":[241],"considering":[242],"patient,":[247],"remaining":[248],"life-expectancy":[249],"severity":[251],"co-morbid":[253],"conditions.":[254],"Short":[255],"acting":[256],"secretogogues":[258],"preferred":[260],"avoid":[262],"prolonged":[263],"frequent":[265],"hypoglycemia.":[266],"Judicious":[267],"choice":[268],"sensitizers,":[271],"timely":[272],"introduction":[273],"insulin,":[275],"meticulous":[276],"control":[277],"hypertension":[279],"hyperlipidemia":[281],"critical":[283]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}