{"id":"https://openalex.org/W1768050488","doi":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","title":"Gene stacking in transgenic plants \u2013 the challenge for 21st century plant biotechnology","display_name":"Gene stacking in transgenic plants \u2013 the challenge for 21st century plant biotechnology","publication_year":2005,"publication_date":"2005-02-03","ids":{"openalex":"https://openalex.org/W1768050488","doi":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","mag":"1768050488","pmid":"https://pubmed.ncbi.nlm.nih.gov/17173615"},"language":"en","primary_location":{"id":"doi:10.1111/j.1467-7652.2004.00113.x","doi":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1467-7652.2004.00113.x","source":{"id":"https://openalex.org/S36510773","display_name":"Plant Biotechnology Journal","issn_l":"1467-7644","issn":["1467-7644","1467-7652"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Biotechnology Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1467-7652.2004.00113.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075463175","display_name":"Claire Halpin","orcid":"https://orcid.org/0000-0002-1808-8130","observed_orcids":["https://orcid.org/0000-0002-1808-8130"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Claire Halpin","raw_affiliation_strings":["Plant Research Unit, School of Life Sciences, University of Dundee at SCRI, Invergowrie, Dundee DD2 5DA, UK. c.halpin@dundee.ac.uk","Plant Research Unit, School of Life Sciences, University of Dundee at SCRI, Invergowrie, Dundee DD2 5DA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plant Research Unit, School of Life Sciences, University of Dundee at SCRI, Invergowrie, Dundee DD2 5DA, UK. c.halpin@dundee.ac.uk","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"Plant Research Unit, School of Life Sciences, University of Dundee at SCRI, Invergowrie, Dundee DD2 5DA, UK","institution_ids":["https://openalex.org/I177639307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075463175"],"corresponding_institution_ids":["https://openalex.org/I177639307"],"apc_list":{"value":4320,"currency":"USD","value_usd":4320},"apc_paid":null,"fwci":23.8434,"has_fulltext":true,"cited_by_count":405,"citation_normalized_percentile":{"value":0.99635915,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"3","issue":"2","first_page":"141","last_page":"155"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.7515000104904175,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.7515000104904175,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":0.22419999539852142,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.01590000092983246,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-stacking","display_name":"gene stacking","score":0.9890000224113464},{"id":"https://openalex.org/keywords/genetically-modified-plants","display_name":"transgenic plants","score":0.8679999709129333},{"id":"https://openalex.org/keywords/genetically-modified-crops","display_name":"genetically modified crops","score":0.7400000095367432},{"id":"https://openalex.org/keywords/plant-gene-expression","display_name":"plant gene expression","score":0.6240000128746033},{"id":"https://openalex.org/keywords/plant-genetic-engineering","display_name":"plant genetic engineering","score":0.6669999957084656},{"id":"https://openalex.org/keywords/transformation-techniques","display_name":"transformation techniques","score":0.4090000092983246}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9200761318206787},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.6491886377334595},{"id":"https://openalex.org/C122172344","wikidata":"https://www.wikidata.org/wiki/Q1503477","display_name":"Genetically modified crops","level":4,"score":0.5982282757759094},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.5587942004203796},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5079460740089417},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3818933367729187},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36359459161758423},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30912941694259644}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1111/j.1467-7652.2004.00113.x","doi":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1467-7652.2004.00113.x","source":{"id":"https://openalex.org/S36510773","display_name":"Plant Biotechnology Journal","issn_l":"1467-7644","issn":["1467-7644","1467-7652"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Biotechnology Journal","raw_type":"journal-article"},{"id":"pmid:17173615","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17173615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant biotechnology journal","raw_type":"Journal Article"},{"id":"pmh:oai:discovery.dundee.ac.uk:openaire/09ee26a3-2f7b-4485-9f96-5438dfe71f7b","doi":null,"is_oa":true,"landing_page_url":"https://discovery.dundee.ac.uk/en/publications/09ee26a3-2f7b-4485-9f96-5438dfe71f7b","pdf_url":null,"source":{"id":"https://openalex.org/S4306400523","display_name":"Discovery Research Portal (University of Dundee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177639307","host_organization_name":"University of Dundee","host_organization_lineage":["https://openalex.org/I177639307"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Halpin, C 2005, 'Gene stacking in transgenic plants - the challenge for 21st century plant biotechnology', Plant Biotechnology Journal, vol. 3, no. 2, pp. 141-155. https://doi.org/10.1111/j.1467-7652.2004.00113.x","raw_type":"info:eu-repo/semantics/review"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1004.4001","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1004.4001","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.researchgate.net/profile/Claire_Halpin2/publication/6625726_Gene_stacking_in_transgenic_plants--the_challenge_for_21st_century_plant_biotechnology/links/00b4952c6f933c42e7000000.pdf?origin%3Dpublication_detail","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1006.444","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1006.444","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.researchgate.net/profile/Claire_Halpin2/publication/6625726_Gene_stacking_in_transgenic_plants--the_challenge_for_21st_century_plant_biotechnology/links/00b4952c6f933c42e7000000.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1007.8722","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1007.8722","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.researchgate.net/profile/Claire_Halpin2/publication/6625726_Halpin_C._Gene_stacking_in_transgenic_plants-the_challenge_for_21st_century_plant_biotechnology._Plant_Biotechnol_J_3_141-155/links/00b4952c6f933c42e7000000.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.992.7897","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.992.7897","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.researchgate.net/profile/Claire_Halpin2/publication/6625726_Gene_stacking_in_transgenic_plants-the_challenge_for_21st_century_plant_biotechnology._Plant_Biotechnol_J_3_141-155/links/00b4952c6f933c42e7000000.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1111/j.1467-7652.2004.00113.x","doi":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1467-7652.2004.00113.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1467-7652.2004.00113.x","source":{"id":"https://openalex.org/S36510773","display_name":"Plant Biotechnology Journal","issn_l":"1467-7644","issn":["1467-7644","1467-7652"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Biotechnology Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.6735000014305115,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1768050488.pdf","grobid_xml":"https://content.openalex.org/works/W1768050488.grobid-xml"},"referenced_works_count":106,"referenced_works":["https://openalex.org/W81770158","https://openalex.org/W227845122","https://openalex.org/W277603247","https://openalex.org/W334627992","https://openalex.org/W1490693026","https://openalex.org/W1497825527","https://openalex.org/W1500657464","https://openalex.org/W1502263497","https://openalex.org/W1503808713","https://openalex.org/W1509665269","https://openalex.org/W1523062281","https://openalex.org/W1553335981","https://openalex.org/W1555522701","https://openalex.org/W1560489919","https://openalex.org/W1561911550","https://openalex.org/W1566617215","https://openalex.org/W1576176252","https://openalex.org/W1585483179","https://openalex.org/W1594570008","https://openalex.org/W1597173461","https://openalex.org/W1947410838","https://openalex.org/W1965668364","https://openalex.org/W1970215128","https://openalex.org/W1970853945","https://openalex.org/W1972319704","https://openalex.org/W1978880365","https://openalex.org/W1980279781","https://openalex.org/W1980554538","https://openalex.org/W1981089845","https://openalex.org/W1982998601","https://openalex.org/W1987901908","https://openalex.org/W1988233266","https://openalex.org/W1991254429","https://openalex.org/W1991763885","https://openalex.org/W1994565125","https://openalex.org/W2000919113","https://openalex.org/W2004145987","https://openalex.org/W2004510914","https://openalex.org/W2005982879","https://openalex.org/W2007107932","https://openalex.org/W2009891608","https://openalex.org/W2011001575","https://openalex.org/W2014036417","https://openalex.org/W2014870946","https://openalex.org/W2016739076","https://openalex.org/W2019622811","https://openalex.org/W2022291463","https://openalex.org/W2022837841","https://openalex.org/W2026568535","https://openalex.org/W2028934193","https://openalex.org/W2029625075","https://openalex.org/W2042272250","https://openalex.org/W2045310728","https://openalex.org/W2046936602","https://openalex.org/W2054798986","https://openalex.org/W2057720426","https://openalex.org/W2060312809","https://openalex.org/W2063286491","https://openalex.org/W2064484011","https://openalex.org/W2065788766","https://openalex.org/W2067041321","https://openalex.org/W2067519351","https://openalex.org/W2070617790","https://openalex.org/W2073696849","https://openalex.org/W2082371246","https://openalex.org/W2082546405","https://openalex.org/W2083816119","https://openalex.org/W2088467693","https://openalex.org/W2090933899","https://openalex.org/W2091567552","https://openalex.org/W2091938644","https://openalex.org/W2092101594","https://openalex.org/W2092213744","https://openalex.org/W2094368613","https://openalex.org/W2096147748","https://openalex.org/W2096765842","https://openalex.org/W2103241013","https://openalex.org/W2103373169","https://openalex.org/W2104755276","https://openalex.org/W2106580201","https://openalex.org/W2106823467","https://openalex.org/W2114144515","https://openalex.org/W2118059183","https://openalex.org/W2118098918","https://openalex.org/W2124986865","https://openalex.org/W2126436260","https://openalex.org/W2127936231","https://openalex.org/W2128094872","https://openalex.org/W2128377922","https://openalex.org/W2137041498","https://openalex.org/W2142137494","https://openalex.org/W2143875485","https://openalex.org/W2144782250","https://openalex.org/W2144979950","https://openalex.org/W2146181288","https://openalex.org/W2146227765","https://openalex.org/W2146577806","https://openalex.org/W2160470234","https://openalex.org/W2163846919","https://openalex.org/W2164114163","https://openalex.org/W2165655968","https://openalex.org/W2166537694","https://openalex.org/W2168920394","https://openalex.org/W2170941862","https://openalex.org/W4231066781","https://openalex.org/W4241961806"],"related_works":["https://openalex.org/W53553842","https://openalex.org/W1544601401","https://openalex.org/W7096763936","https://openalex.org/W2388096442","https://openalex.org/W4246262787","https://openalex.org/W2045990180","https://openalex.org/W4295665340","https://openalex.org/W3212102032","https://openalex.org/W1987126503","https://openalex.org/W2767475777"],"abstract_inverted_index":{"One":[0],"of":[1,9,23,37,51,69,98],"the":[2,7,16,19,64,94,107,114],"major":[3],"technical":[4],"hurdles":[5],"impeding":[6],"advance":[8],"plant":[10],"genetic":[11],"engineering":[12],"and":[13,71,96,102,106],"biotechnology":[14],"is":[15,28],"fact":[17],"that":[18],"expression":[20],"or":[21,45,59],"manipulation":[22],"multiple":[24,80],"genes":[25,81],"in":[26,113],"plants":[27],"still":[29],"difficult":[30],"to":[31,78],"achieve.":[32],"Although":[33],"a":[34,49,67],"small":[35],"proportion":[36],"commercial":[38],"genetically":[39],"modified":[40],"(GM)":[41],"crops":[42],"present":[43],"'stacked'":[44],"'pyramided'":[46],"traits,":[47],"only":[48],"handful":[50],"products":[52],"have":[53,75],"been":[54,76],"developed":[55],"by":[56],"introducing":[57],"three":[58],"more":[60,72],"novel":[61,73],"genes.":[62],"On":[63],"research":[65],"front,":[66],"variety":[68],"conventional":[70],"methods":[74],"employed":[77],"introduce":[79],"into":[82],"plants,":[83],"but":[84],"all":[85],"techniques":[86,101],"suffer":[87],"from":[88],"certain":[89],"drawbacks.":[90],"In":[91],"this":[92],"review,":[93],"potential":[95],"problems":[97],"these":[99,111],"various":[100],"strategies":[103],"are":[104,116],"discussed,":[105],"prospects":[108],"for":[109],"improving":[110],"technologies":[112],"future":[115],"presented.":[117]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":17},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":26},{"year":2016,"cited_by_count":21},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":29},{"year":2013,"cited_by_count":18},{"year":2012,"cited_by_count":37}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
