{"id":"https://openalex.org/W1761237796","doi":"https://doi.org/10.1093/oxfordjournals.ndt.a091987","title":"Dextran Antibodies, Complement Conversion and Circulating Immune Complexes After Intravenous Iron Dextran Therapy in Dialysed Patients","display_name":"Dextran Antibodies, Complement Conversion and Circulating Immune Complexes After Intravenous Iron Dextran Therapy in Dialysed Patients","publication_year":1992,"publication_date":"1992-01-01","ids":{"openalex":"https://openalex.org/W1761237796","doi":"https://doi.org/10.1093/oxfordjournals.ndt.a091987","mag":"1761237796","pmid":"https://pubmed.ncbi.nlm.nih.gov/1337181"},"language":"en","primary_location":{"id":"doi:10.1093/oxfordjournals.ndt.a091987","doi":"https://doi.org/10.1093/oxfordjournals.ndt.a091987","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.ndt.a091987","pdf_url":null,"source":{"id":"https://openalex.org/S186113128","display_name":"Nephrology Dialysis Transplantation","issn_l":"0931-0509","issn":["0931-0509","1460-2385"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology Dialysis Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112180893","display_name":"Laura W. Fleming","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["FI","GB"],"is_corresponding":true,"raw_author_name":"Laura W. Fleming","raw_affiliation_strings":["Departments of Medicine, University of Dundee, Ninewells Hospital and Medical School 1 Dundee, Scotland, UK","IV Department of Medicine, Helsinki University Central Hospital, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, University of Dundee, Ninewells Hospital and Medical School 1 Dundee, Scotland, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]},{"raw_affiliation_string":"IV Department of Medicine, Helsinki University Central Hospital, Finland","institution_ids":["https://openalex.org/I2800394112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076518759","display_name":"W.K. Stewart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W. K. Stewart","raw_affiliation_strings":["Departments of Medicine, University of Dundee, Ninewells Hospital and Medical School 1 Dundee, Scotland, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, University of Dundee, Ninewells Hospital and Medical School 1 Dundee, Scotland, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]}]},{"author_position":"last","author":{"id":null,"display_name":"D. Parratt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]},{"id":"https://openalex.org/I2802526638","display_name":"Ninewells Hospital","ror":"https://ror.org/039c6rk82","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800860831","https://openalex.org/I2802526638"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. Parratt","raw_affiliation_strings":["Departments of Medical Microbiology, University of Dundee, Ninewells Hospital and Medical School 2 Dundee, Scotland, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medical Microbiology, University of Dundee, Ninewells Hospital and Medical School 2 Dundee, Scotland, UK","institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2802526638"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5112180893"],"corresponding_institution_ids":["https://openalex.org/I177639307","https://openalex.org/I2800394112","https://openalex.org/I2802526638"],"apc_list":{"value":3474,"currency":"EUR","value_usd":3926},"apc_paid":null,"fwci":1.055,"has_fulltext":false,"cited_by_count":65,"citation_normalized_percentile":{"value":0.75978331,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"7","issue":"1","first_page":"35","last_page":"39"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.4684999883174896,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.4684999883174896,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.1662999987602234,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.09589999914169312,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iron-dextran","display_name":"iron dextran","score":0.9810000061988831},{"id":"https://openalex.org/keywords/immune-complexes","display_name":"immune complexes","score":0.6850000023841858},{"id":"https://openalex.org/keywords/hemodialysis-patients","display_name":"hemodialysis patients","score":0.7409999966621399},{"id":"https://openalex.org/keywords/iron-supplementation","display_name":"iron supplementation","score":0.6449999809265137},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.7310000061988831},{"id":"https://openalex.org/keywords/joint-inflammation","display_name":"joint inflammation","score":0.7250000238418579}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8910082578659058},{"id":"https://openalex.org/C2777339698","wikidata":"https://www.wikidata.org/wiki/Q423123","display_name":"Dextran","level":2,"score":0.8898974657058716},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6848272681236267},{"id":"https://openalex.org/C112313634","wikidata":"https://www.wikidata.org/wiki/Q7886648","display_name":"Complement (music)","level":5,"score":0.55510413646698},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5444841980934143},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.4458490312099457},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4367353618144989},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07266533374786377},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.0},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015433","descriptor_name":"Glomerulonephritis, Membranous","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D015433","descriptor_name":"Glomerulonephritis, Membranous","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015433","descriptor_name":"Glomerulonephritis, Membranous","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/oxfordjournals.ndt.a091987","doi":"https://doi.org/10.1093/oxfordjournals.ndt.a091987","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.ndt.a091987","pdf_url":null,"source":{"id":"https://openalex.org/S186113128","display_name":"Nephrology Dialysis Transplantation","issn_l":"0931-0509","issn":["0931-0509","1460-2385"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology Dialysis Transplantation","raw_type":"journal-article"},{"id":"pmid:1337181","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1337181","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association","raw_type":"Journal Article"},{"id":"pmid:1374865","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1374865","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.932.5253","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.932.5253","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ndt.oxfordjournals.org/content/7/1/35.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7098777034","https://openalex.org/W2498398935","https://openalex.org/W2028474339","https://openalex.org/W2966839852","https://openalex.org/W2554323110","https://openalex.org/W2034135748","https://openalex.org/W2804085607","https://openalex.org/W2037229566","https://openalex.org/W2415819907","https://openalex.org/W4298209663"],"abstract_inverted_index":{"Serum":[0],"immune":[1,43,158],"complexes,":[2],"plasma":[3],"dextran":[4,26,48,100,142,151,167],"antibodies":[5,49,143],"and":[6,19,36,89,130,156,160],"percentage":[7],"conversion":[8,33],"of":[9,24,47,83,118,141,149],"complement":[10,161],"have":[11],"been":[12],"measured":[13,129],"in":[14,41,50,68,80],"20":[15],"dialysed":[16],"patients":[17,52,70,85,120,153],"before":[18,53],"after":[20,73,111],"an":[21],"intravenous":[22],"infusion":[23,55,96,114],"iron":[25,63,150,166],"providing":[27],"600":[28],"mg":[29],"elemental":[30],"iron.":[31],"Complement":[32],"was":[34,56],"unmeasurable":[35],"there":[37],"were":[38,127],"no":[39,98],"changes":[40],"circulating":[42],"complexes.":[44],"The":[45,123,139],"presence":[46,140],"nine":[51],"the":[54,74,92,95,119,137,147,157],"not":[57,132,145],"related":[58],"to":[59,62,116,134,136,152],"prior":[60],"exposure":[61],"dextran.":[64],"They":[65],"became":[66],"undetectable":[67],"these":[69],"within":[71],"hours":[72],"infusion,":[75],"reappearing":[76],"1":[77],"month":[78],"later":[79],"three.":[81],"Two":[82],"three":[84],"reporting":[86],"mild":[87],"aches":[88],"shivers":[90],"on":[91,154],"day":[93],"following":[94],"had":[97],"detectable":[99],"antibodies.":[101],"An":[102],"adverse":[103],"reaction":[104],"involving":[105],"inflamed":[106],"joints":[107],"occurred":[108],"1-2":[109],"days":[110],"a":[112],"second":[113],"given":[115],"one":[117],"studied":[121],"above.":[122],"parameters":[124],"under":[125],"study":[126],"again":[128],"did":[131],"appear":[133],"relate":[135],"reaction.":[138],"does":[144],"preclude":[146],"giving":[148],"dialysis,":[155],"complex":[159],"systems":[162],"remain":[163],"undisturbed":[164],"by":[165],"infusions.":[168]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}