{"id":"https://openalex.org/W175744166","doi":"https://doi.org/10.1042/bj1300697","title":"The activities of lipases and carnitine palmitoyl-transferase in muscles from vertebrates and invertebrates","display_name":"The activities of lipases and carnitine palmitoyl-transferase in muscles from vertebrates and invertebrates","publication_year":1972,"publication_date":"1972-12-01","ids":{"openalex":"https://openalex.org/W175744166","doi":"https://doi.org/10.1042/bj1300697","mag":"175744166","pmid":"https://pubmed.ncbi.nlm.nih.gov/4664927","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1174508"},"language":"en","primary_location":{"id":"doi:10.1042/bj1300697","doi":"https://doi.org/10.1042/bj1300697","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj1300697","pdf_url":"https://portlandpress.com/biochemj/article-pdf/130/3/697/779702/bj1300697.pdf","source":{"id":"https://openalex.org/S4210234214","display_name":"Biochemical Journal","issn_l":"0306-3283","issn":["0306-3283"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://portlandpress.com/biochemj/article-pdf/130/3/697/779702/bj1300697.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111890128","display_name":"B. Crabtree","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"B. Crabtree","raw_affiliation_strings":["Agricultural Research Council Unit of Insect Physiology, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Research Council Unit of Insect Physiology, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, U.K","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109996558","display_name":"Eric A. Newsholme","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. A. Newsholme","raw_affiliation_strings":["Agricultural Research Council Unit of Insect Physiology, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Research Council Unit of Insect Physiology, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, U.K","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":null,"apc_paid":null,"fwci":1.838,"has_fulltext":true,"cited_by_count":142,"citation_normalized_percentile":{"value":0.81259761,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"130","issue":"3","first_page":"697","last_page":"705"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipase","display_name":"lipase","score":0.6790000200271606},{"id":"https://openalex.org/keywords/carnitine-palmitoyltransferase","display_name":"carnitine palmitoyltransferase","score":0.9800000190734863},{"id":"https://openalex.org/keywords/triacylglycerol-lipase","display_name":"triacylglycerol lipase","score":0.9279999732971191},{"id":"https://openalex.org/keywords/monoglyceride-lipase","display_name":"monoglyceride lipase","score":0.9340000152587891},{"id":"https://openalex.org/keywords/insect-flight-muscle","display_name":"insect flight muscle","score":0.7149999737739563},{"id":"https://openalex.org/keywords/glycerol-kinase","display_name":"glycerol kinase","score":0.875},{"id":"https://openalex.org/keywords/fatty-acid-utilization","display_name":"fatty acid utilization","score":0.8149999976158142},{"id":"https://openalex.org/keywords/locusts","display_name":"locusts","score":0.7609999775886536},{"id":"https://openalex.org/keywords/bees","display_name":"bees","score":0.45899999141693115},{"id":"https://openalex.org/keywords/wasps","display_name":"wasps","score":0.7009999752044678},{"id":"https://openalex.org/keywords/moths","display_name":"moths","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C13474642","wikidata":"https://www.wikidata.org/wiki/Q43806","display_name":"Invertebrate","level":2,"score":0.6482423543930054},{"id":"https://openalex.org/C2778435403","wikidata":"https://www.wikidata.org/wiki/Q243309","display_name":"Carnitine","level":2,"score":0.6393095254898071},{"id":"https://openalex.org/C2776376580","wikidata":"https://www.wikidata.org/wiki/Q407355","display_name":"Transferase","level":3,"score":0.5704846382141113},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.45060184597969055},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4250413775444031},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37568098306655884},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34163057804107666},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.29005521535873413},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.28050127625465393}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001516","descriptor_name":"Bees","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002331","descriptor_name":"Carnitine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004175","descriptor_name":"Diptera","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005989","descriptor_name":"Glycerides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006110","descriptor_name":"Grasshoppers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008049","descriptor_name":"Lipase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010169","descriptor_name":"Palmitic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010770","descriptor_name":"Phosphotransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010856","descriptor_name":"Columbidae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012487","descriptor_name":"Salmonidae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014166","descriptor_name":"Transferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1042/bj1300697","doi":"https://doi.org/10.1042/bj1300697","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj1300697","pdf_url":"https://portlandpress.com/biochemj/article-pdf/130/3/697/779702/bj1300697.pdf","source":{"id":"https://openalex.org/S4210234214","display_name":"Biochemical Journal","issn_l":"0306-3283","issn":["0306-3283"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1174508","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1174508","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochem J","raw_type":"Text"},{"id":"pmid:4664927","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4664927","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Biochemical journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1042/bj1300697","doi":"https://doi.org/10.1042/bj1300697","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj1300697","pdf_url":"https://portlandpress.com/biochemj/article-pdf/130/3/697/779702/bj1300697.pdf","source":{"id":"https://openalex.org/S4210234214","display_name":"Biochemical Journal","issn_l":"0306-3283","issn":["0306-3283"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W175744166.pdf","grobid_xml":"https://content.openalex.org/works/W175744166.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W48316491","https://openalex.org/W125962033","https://openalex.org/W177044521","https://openalex.org/W936425006","https://openalex.org/W1524650698","https://openalex.org/W1776938986","https://openalex.org/W1819194792","https://openalex.org/W2006188156","https://openalex.org/W2028466493","https://openalex.org/W2034562003","https://openalex.org/W2035989782","https://openalex.org/W2069052642","https://openalex.org/W2087831430","https://openalex.org/W2156440499","https://openalex.org/W2162367000","https://openalex.org/W2211459314","https://openalex.org/W2277927570","https://openalex.org/W2282232393","https://openalex.org/W2312579002","https://openalex.org/W2405222357","https://openalex.org/W2411377083","https://openalex.org/W2418051006","https://openalex.org/W2421267915","https://openalex.org/W2443129672","https://openalex.org/W4238205543","https://openalex.org/W6601180670","https://openalex.org/W6605335442"],"related_works":["https://openalex.org/W1776938986","https://openalex.org/W1819194792","https://openalex.org/W2015685324","https://openalex.org/W1993010945","https://openalex.org/W2055322437","https://openalex.org/W2012328460","https://openalex.org/W2164602387","https://openalex.org/W2327344586","https://openalex.org/W3160747659","https://openalex.org/W1945935204"],"abstract_inverted_index":{"1.":[0],"The":[1,91],"activities":[2,22],"of":[3,16,19,29,31,43,80,82,93,102,119,132,153,160,172,178,191,199],"tri-,":[4],"di-":[5],"and":[6,9,33,69,109,112,122,149],"mono-glyceride":[7],"lipase":[8,95],"carnitine":[10],"palmitoyltransferase":[11],"were":[12,23],"measured":[13],"in":[14,85,98,115,166,184,209],"homogenates":[15],"a":[17,135,203],"variety":[18],"muscles.":[20,141,211],"These":[21,125],"used":[24],"to":[25,158],"estimate":[26],"the":[27,53,67,77,86,99,106,116,123,130,151,169,176,189],"rate":[28],"utilization":[30,45,131],"glycerides":[32,83],"fatty":[34],"acids":[35],"by":[36],"muscle.":[37],"In":[38,73,143],"muscles":[39,75,101,118,145,168,188],"whose":[40],"estimated":[41,68],"rates":[42,50,79],"fat":[44],"can":[46],"be":[47],"compared":[48],"with":[49,129],"calculated":[51,70],"for":[52,137,206],"intact":[54],"muscle":[55],"from":[56,146],"such":[57,104],"information":[58],"as":[59,105,134],"O(2)":[60],"uptake,":[61],"there":[62],"is":[63,96,113,156,163,175,194],"reasonable":[64],"agreement":[65],"between":[66],"rates.":[71],"2.":[72],"all":[74],"investigated":[76],"maximum":[78],"hydrolysis":[81],"increase":[84],"order":[87],"triglyceride,":[88],"diglyceride,":[89],"monoglyceride.":[90],"activity":[92,152,190],"diglyceride":[94,133],"highest":[97],"flight":[100,117,140,187],"insects":[103],"locust,":[107],"waterbug":[108],"some":[110,138,185],"moths":[111],"lowest":[114],"flies,":[120],"bees":[121],"wasp.":[124],"results":[126],"are":[127],"consistent":[128],"fuel":[136],"insect":[139,186],"3.":[142],"many":[144],"both":[147],"vertebrates":[148],"invertebrates":[150],"glycerol":[154,173,179,192,207],"kinase":[155,174,193,208],"similar":[157],"that":[159,165,198],"lipase.":[161],"It":[162],"concluded":[164],"these":[167,210],"metabolic":[170],"role":[171,205],"removal":[177],"produced":[180],"during":[181],"lipolysis.":[182],"However,":[183],"much":[195],"greater":[196],"than":[197],"lipase,":[200],"which":[201],"suggests":[202],"different":[204]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}