{"id":"https://openalex.org/W175235608","doi":"https://doi.org/10.1093/ajcp/51.6.765","title":"Fecal Contamination in Urine Amino Acid Screening: Artifactual Cause of Hyperaminoaciduria","display_name":"Fecal Contamination in Urine Amino Acid Screening: Artifactual Cause of Hyperaminoaciduria","publication_year":1969,"publication_date":"1969-06-01","ids":{"openalex":"https://openalex.org/W175235608","doi":"https://doi.org/10.1093/ajcp/51.6.765","mag":"175235608","pmid":"https://pubmed.ncbi.nlm.nih.gov/5770673"},"language":"en","primary_location":{"id":"doi:10.1093/ajcp/51.6.765","doi":"https://doi.org/10.1093/ajcp/51.6.765","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/51.6.765","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112778417","display_name":"Harvey L. Levy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1337960435","display_name":"Massachusetts Department of Public Health","ror":"https://ror.org/050c9qp51","country_code":"US","type":"government","lineage":["https://openalex.org/I1337960435","https://openalex.org/I402481858"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harvey L. Levy","raw_affiliation_strings":["Department of Neurology, Harvard Medical School, Joseph P. Kennedy, Jr. Laboratories, Massachusetts General Hospital, and the Stale Laboratory Institute, Diagnostic Division, Massachusetts Department of Public Health, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Joseph P. Kennedy, Jr. Laboratories, Massachusetts General Hospital, and the Stale Laboratory Institute, Diagnostic Division, Massachusetts Department of Public Health, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I1337960435","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017939629","display_name":"Phyllis M. Madigan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1337960435","display_name":"Massachusetts Department of Public Health","ror":"https://ror.org/050c9qp51","country_code":"US","type":"government","lineage":["https://openalex.org/I1337960435","https://openalex.org/I402481858"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Phyllis M. Madigan","raw_affiliation_strings":["Department of Neurology, Harvard Medical School, Joseph P. Kennedy, Jr. Laboratories, Massachusetts General Hospital, and the Stale Laboratory Institute, Diagnostic Division, Massachusetts Department of Public Health, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Joseph P. Kennedy, Jr. Laboratories, Massachusetts General Hospital, and the Stale Laboratory Institute, Diagnostic Division, Massachusetts Department of Public Health, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I1337960435","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007708498","display_name":"Ann Lum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1337960435","display_name":"Massachusetts Department of Public Health","ror":"https://ror.org/050c9qp51","country_code":"US","type":"government","lineage":["https://openalex.org/I1337960435","https://openalex.org/I402481858"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ann Lum","raw_affiliation_strings":["Department of Neurology, Harvard Medical School, Joseph P. Kennedy, Jr. Laboratories, Massachusetts General Hospital, and the Stale Laboratory Institute, Diagnostic Division, Massachusetts Department of Public Health, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Joseph P. Kennedy, Jr. Laboratories, Massachusetts General Hospital, and the Stale Laboratory Institute, Diagnostic Division, Massachusetts Department of Public Health, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I1337960435","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4660,"currency":"USD","value_usd":4660},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.01460565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"51","issue":"6","first_page":"765","last_page":"768"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.5151000022888184,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.5151000022888184,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.46239998936653137,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.014100000262260437,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fecal-contamination","display_name":"fecal contamination","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hyperaminoaciduria","display_name":"hyperaminoaciduria","score":0.9959999918937683},{"id":"https://openalex.org/keywords/artifacts","display_name":"artifacts","score":0.6769999861717224},{"id":"https://openalex.org/keywords/false-positive-results","display_name":"false positives","score":0.5830000042915344},{"id":"https://openalex.org/keywords/aminoaciduria","display_name":"aminoaciduria","score":0.42500001192092896}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5809177160263062},{"id":"https://openalex.org/C2993838110","wikidata":"https://www.wikidata.org/wiki/Q494230","display_name":"Medical school","level":2,"score":0.564355731010437},{"id":"https://openalex.org/C2992019943","wikidata":"https://www.wikidata.org/wiki/Q16917","display_name":"General hospital","level":2,"score":0.5486364364624023},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.488412082195282},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.4165683388710022},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.40684565901756287},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3736077547073364},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.14219164848327637},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.12683194875717163},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000592","descriptor_name":"Amino Acid Metabolism, Inborn Errors","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D002845","descriptor_name":"Chromatography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006250","descriptor_name":"Hartnup Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008722","descriptor_name":"Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010209","descriptor_name":"Paper","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013048","descriptor_name":"Specimen Handling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014556","descriptor_name":"Urine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/ajcp/51.6.765","doi":"https://doi.org/10.1093/ajcp/51.6.765","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/51.6.765","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},{"id":"pmid:5770673","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5770673","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of clinical pathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1566406366","https://openalex.org/W2010109087","https://openalex.org/W2233132489","https://openalex.org/W2407934908"],"related_works":["https://openalex.org/W4300583313","https://openalex.org/W2045658894","https://openalex.org/W2402677281","https://openalex.org/W2080147299","https://openalex.org/W2418438702","https://openalex.org/W2411111317","https://openalex.org/W3003122669","https://openalex.org/W2461455360","https://openalex.org/W2038140994","https://openalex.org/W1989882754"],"abstract_inverted_index":{"Harvey":[0],"L.":[1],"Levy,":[2],"M.D.,":[3],"Phyllis":[4],"M.":[5],"Madigan,":[6],"B.A.,":[7],"Ann":[8],"Lum,":[9],"A.B.;":[10],"Fecal":[11],"Contamination":[12],"in":[13],"Urine":[14],"Amino":[15],"Acid":[16],"Screening:":[17],"Artifactual":[18],"Cause":[19],"of":[20],"Hyperaminoaciduria,":[21]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}