{"id":"https://openalex.org/W1745698293","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a135442","title":"Structural Comparisons between Mouse and Human Prealbumin1","display_name":"Structural Comparisons between Mouse and Human Prealbumin1","publication_year":1985,"publication_date":"1985-12-01","ids":{"openalex":"https://openalex.org/W1745698293","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a135442","mag":"1745698293","pmid":"https://pubmed.ncbi.nlm.nih.gov/3005251"},"language":"en","primary_location":{"id":"doi:10.1093/oxfordjournals.jbchem.a135442","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a135442","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.jbchem.a135442","pdf_url":null,"source":{"id":"https://openalex.org/S184547178","display_name":"The Journal of Biochemistry","issn_l":"0021-924X","issn":["0021-924X","1756-2651"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113675482","display_name":"Shoji Wakasugi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shoji WAKASUGI","raw_affiliation_strings":["Department of Biochemistry, Kumamoto University Medical School Honjo, Kumamoto, Kumamoto 860"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kumamoto University Medical School Honjo, Kumamoto, Kumamoto 860","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111969108","display_name":"Shuichiro Maeda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shuichiro MAEDA","raw_affiliation_strings":["Department of Biochemistry, Kumamoto University Medical School Honjo, Kumamoto, Kumamoto 860"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kumamoto University Medical School Honjo, Kumamoto, Kumamoto 860","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030757256","display_name":"\u548c\u5178 \u5cf6\u7530","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kazunori SHIMADA","raw_affiliation_strings":["Department of Biochemistry, Kumamoto University Medical School Honjo, Kumamoto, Kumamoto 860"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kumamoto University Medical School Honjo, Kumamoto, Kumamoto 860","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054093764","display_name":"Hiroshi Nakashima","orcid":"https://orcid.org/0000-0001-9678-9234","observed_orcids":["https://orcid.org/0000-0001-9678-9234"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi NAKASHIMA","raw_affiliation_strings":["School of Allied Medical Professions, Kanazawa University Kanazawa, Ishikawa 920"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Allied Medical Professions, Kanazawa University Kanazawa, Ishikawa 920","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018319163","display_name":"Shunsuke Migita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]},{"id":"https://openalex.org/I4405286179","display_name":"Cancer Research Institute of Kanazawa University","ror":"https://ror.org/01bve4846","country_code":"JP","type":"facility","lineage":["https://openalex.org/I10091056","https://openalex.org/I4405286179"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shunsuke MIGITA","raw_affiliation_strings":["Department of Molecular Immunology, Cancer Research Institute, Kanazawa University Kanazawa, Ishikawa 920"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Immunology, Cancer Research Institute, Kanazawa University Kanazawa, Ishikawa 920","institution_ids":["https://openalex.org/I10091056","https://openalex.org/I4405286179"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5030757256"],"corresponding_institution_ids":["https://openalex.org/I96036126"],"apc_list":{"value":3276,"currency":"USD","value_usd":3276},"apc_paid":null,"fwci":1.3258,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.79451358,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"98","issue":"6","first_page":"1707","last_page":"1714"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prealbumin","display_name":"prealbumin","score":0.8960000276565552},{"id":"https://openalex.org/keywords/familial-amyloid-polyneuropathy","display_name":"hereditary transthyretin amyloidosis","score":0.9200000166893005},{"id":"https://openalex.org/keywords/comparative-sequence-analysis","display_name":"sequence comparison","score":0.460999995470047},{"id":"https://openalex.org/keywords/signal-peptide","display_name":"signal peptide","score":0.6340000033378601},{"id":"https://openalex.org/keywords/primary-structure","display_name":"primary structure","score":0.6830000281333923},{"id":"https://openalex.org/keywords/amino-acid-substitutions","display_name":"amino acid substitutions","score":0.6290000081062317},{"id":"https://openalex.org/keywords/protein-structure-conservation","display_name":"protein structure conservation","score":0.7409999966621399},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.8190000057220459}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39698168635368347},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3366234302520752}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000686","descriptor_name":"Amyloidosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000686","descriptor_name":"Amyloidosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010523","descriptor_name":"Peripheral Nervous System Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010523","descriptor_name":"Peripheral Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011228","descriptor_name":"Prealbumin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011228","descriptor_name":"Prealbumin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/oxfordjournals.jbchem.a135442","doi":"https://doi.org/10.1093/oxfordjournals.jbchem.a135442","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.jbchem.a135442","pdf_url":null,"source":{"id":"https://openalex.org/S184547178","display_name":"The Journal of Biochemistry","issn_l":"0021-924X","issn":["0021-924X","1756-2651"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:3005251","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3005251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biochemistry","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1992607563","https://openalex.org/W2012206867","https://openalex.org/W1542856731","https://openalex.org/W2062210778","https://openalex.org/W2267072526","https://openalex.org/W1945431375","https://openalex.org/W2407736679","https://openalex.org/W2419640560","https://openalex.org/W2086009573","https://openalex.org/W2418287116"],"abstract_inverted_index":{"In":[0],"an":[1],"attempt":[2],"to":[3,123],"construct":[4],"model":[5],"systems":[6],"for":[7,75,142],"familial":[8],"amyloidotic":[9],"polyneuropathy,":[10],"prealbumin":[11,25,36,53],"cDNA":[12,19,26,40,138],"was":[13],"cloned":[14,23,137],"from":[15,38],"a":[16,28,51,59],"mouse":[17,35,99],"liver":[18],"library,":[20],"using":[21],"previously":[22],"human":[24,77,88],"as":[27],"hybridization":[29],"probe.":[30],"The":[31,136],"primary":[32],"structure":[33],"of":[34,46,85,104,116,129],"deduced":[37],"the":[39,76,80,86,98,105,113,117,120,124,130],"sequence":[41,54,62],"shows":[42],"that":[43],"it":[44],"consists":[45],"147":[47],"amino":[48,56,64,82,95,108],"acids,":[49],"including":[50],"whole":[52],"(127":[55],"acids)":[57],"and":[58,119,126],"putative":[60],"signal":[61],"(20":[63],"acids).":[65],"These":[66],"numbers":[67],"are":[68,91,110,132],"in":[69,97,145],"complete":[70],"agreement":[71],"with":[72],"those":[73],"determined":[74],"prealbumin.":[78,100],"Among":[79],"127":[81],"acid":[83],"residues":[84],"mature":[87],"prealbumin,":[89],"25":[90,106],"replaced":[92],"by":[93],"different":[94],"acids":[96,109],"Interestingly,":[101],"24":[102],"out":[103],"substituted":[107],"located":[111],"at":[112],"outer":[114],"surface":[115],"protein,":[118],"regions":[121],"corresponding":[122],"core":[125],"central":[127],"channel":[128],"protein":[131],"almost":[133],"completely":[134],"conserved.":[135],"provided":[139],"essential":[140],"information":[141],"manipulating":[143],"amyloidosis":[144],"mice.":[146]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}