{"id":"https://openalex.org/W1743436688","doi":"https://doi.org/10.17169/refubium-11273","title":"Antikoagulation bei Schlaganfall-Patienten mit Vorhofflimmern","display_name":"Antikoagulation bei Schlaganfall-Patienten mit Vorhofflimmern","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1743436688","doi":"https://doi.org/10.17169/refubium-11273","mag":"1743436688"},"language":"de","primary_location":{"id":"pmh:oai:diss.fu-berlin.de:FUDISS_thesis_000000098323","doi":null,"is_oa":false,"landing_page_url":"http://edocs.fu-berlin.de/diss/receive/FUDISS_thesis_000000098323","pdf_url":null,"source":{"id":"https://openalex.org/S7407052913","display_name":"Universit\u00e4tsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://refubium.fu-berlin.de/handle/fub188/7074","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015956806","display_name":"Maria Konieczny","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Konieczny, Maria","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5015956806"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.060600001364946365,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.9860000014305115},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.8320000171661377},{"id":"https://openalex.org/keywords/oral-anticoagulation","display_name":"oral anticoagulation","score":0.9649999737739563},{"id":"https://openalex.org/keywords/vitamin-k-antagonists","display_name":"vitamin K antagonists","score":0.9950000047683716},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.6830000281333923},{"id":"https://openalex.org/keywords/stroke-severity","display_name":"stroke severity","score":0.718999981880188},{"id":"https://openalex.org/keywords/long-term-mortality","display_name":"long-term mortality","score":0.9430000185966492},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.3779999911785126},{"id":"https://openalex.org/keywords/guideline-adherence","display_name":"guideline adherence","score":0.4059999883174896},{"id":"https://openalex.org/keywords/stroke-risk-factors","display_name":"stroke risk factors","score":0.36500000953674316},{"id":"https://openalex.org/keywords/post-stroke-care","display_name":"post-stroke care","score":0.4169999957084656},{"id":"https://openalex.org/keywords/stroke-rehabilitation","display_name":"stroke rehabilitation","score":0.36800000071525574},{"id":"https://openalex.org/keywords/post-stroke-depression","display_name":"post-stroke depression","score":0.45399999618530273}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6497600674629211},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.4377690553665161},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27472156286239624}],"mesh":[],"locations_count":6,"locations":[{"id":"pmh:oai:diss.fu-berlin.de:FUDISS_thesis_000000098323","doi":null,"is_oa":false,"landing_page_url":"http://edocs.fu-berlin.de/diss/receive/FUDISS_thesis_000000098323","pdf_url":null,"source":{"id":"https://openalex.org/S7407052913","display_name":"Universit\u00e4tsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:doctoralThesis"},{"id":"pmh:oai:refubium.fu-berlin.de:fub188/7074","doi":null,"is_oa":true,"landing_page_url":"https://refubium.fu-berlin.de/handle/fub188/7074","pdf_url":"https://refubium.fu-berlin.de/handle/fub188/7074","source":{"id":"https://openalex.org/S4306402444","display_name":"Refubium (Universit\u00e4tsbibliothek der Freien Universit\u00e4t Berlin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I75951250","host_organization_name":"Freie Universit\u00e4t Berlin","host_organization_lineage":["https://openalex.org/I75951250"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},{"id":"pmh:oai:aleph.bib-bvb.de:BVB01-027875063","doi":null,"is_oa":false,"landing_page_url":"http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000098323","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Hochschulschrift"},{"id":"doi:10.17169/refubium-11273","doi":"https://doi.org/10.17169/refubium-11273","is_oa":true,"landing_page_url":"https://doi.org/10.17169/refubium-11273","pdf_url":null,"source":{"id":"https://openalex.org/S7407052913","display_name":"Universit\u00e4tsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"mag:1743436688","doi":null,"is_oa":false,"landing_page_url":"http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000098323?lang=en","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2290840751","doi":null,"is_oa":false,"landing_page_url":"https://refubium.fu-berlin.de/handle/fub188/7074","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:refubium.fu-berlin.de:fub188/7074","doi":null,"is_oa":true,"landing_page_url":"https://refubium.fu-berlin.de/handle/fub188/7074","pdf_url":"https://refubium.fu-berlin.de/handle/fub188/7074","source":{"id":"https://openalex.org/S4306402444","display_name":"Refubium (Universit\u00e4tsbibliothek der Freien Universit\u00e4t Berlin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I75951250","host_organization_name":"Freie Universit\u00e4t Berlin","host_organization_lineage":["https://openalex.org/I75951250"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1743436688.pdf","grobid_xml":"https://content.openalex.org/works/W1743436688.grobid-xml"},"referenced_works_count":102,"referenced_works":["https://openalex.org/W181602246","https://openalex.org/W205152337","https://openalex.org/W308975052","https://openalex.org/W1536873670","https://openalex.org/W1788632313","https://openalex.org/W1969046726","https://openalex.org/W1969661146","https://openalex.org/W1971505725","https://openalex.org/W1980554417","https://openalex.org/W1983977584","https://openalex.org/W1984364985","https://openalex.org/W1986506316","https://openalex.org/W1986637035","https://openalex.org/W1997300706","https://openalex.org/W1999468381","https://openalex.org/W2000372136","https://openalex.org/W2011936209","https://openalex.org/W2015848855","https://openalex.org/W2019712801","https://openalex.org/W2020983205","https://openalex.org/W2021212936","https://openalex.org/W2023143117","https://openalex.org/W2023849073","https://openalex.org/W2025657030","https://openalex.org/W2025672640","https://openalex.org/W2029318131","https://openalex.org/W2029761321","https://openalex.org/W2036411732","https://openalex.org/W2039089847","https://openalex.org/W2048154508","https://openalex.org/W2048895475","https://openalex.org/W2049663681","https://openalex.org/W2051487731","https://openalex.org/W2053999497","https://openalex.org/W2055586130","https://openalex.org/W2056756213","https://openalex.org/W2062786076","https://openalex.org/W2064799192","https://openalex.org/W2065028337","https://openalex.org/W2066098573","https://openalex.org/W2067498563","https://openalex.org/W2068427166","https://openalex.org/W2070467531","https://openalex.org/W2074119210","https://openalex.org/W2080504768","https://openalex.org/W2081885474","https://openalex.org/W2084350674","https://openalex.org/W2084988042","https://openalex.org/W2089534375","https://openalex.org/W2093600267","https://openalex.org/W2096246254","https://openalex.org/W2097211826","https://openalex.org/W2097854437","https://openalex.org/W2099368507","https://openalex.org/W2099654370","https://openalex.org/W2101081523","https://openalex.org/W2104343448","https://openalex.org/W2105486760","https://openalex.org/W2106143461","https://openalex.org/W2108329377","https://openalex.org/W2109556661","https://openalex.org/W2114775432","https://openalex.org/W2117712240","https://openalex.org/W2118876291","https://openalex.org/W2121394112","https://openalex.org/W2127690875","https://openalex.org/W2128143634","https://openalex.org/W2129906781","https://openalex.org/W2131839979","https://openalex.org/W2133359435","https://openalex.org/W2134586715","https://openalex.org/W2135694398","https://openalex.org/W2136489990","https://openalex.org/W2137434301","https://openalex.org/W2137835206","https://openalex.org/W2138595885","https://openalex.org/W2140646485","https://openalex.org/W2141842749","https://openalex.org/W2141889414","https://openalex.org/W2143004627","https://openalex.org/W2144582288","https://openalex.org/W2144785885","https://openalex.org/W2144891869","https://openalex.org/W2147797899","https://openalex.org/W2148056560","https://openalex.org/W2149388786","https://openalex.org/W2150276157","https://openalex.org/W2152538959","https://openalex.org/W2160223544","https://openalex.org/W2160907118","https://openalex.org/W2162508946","https://openalex.org/W2164861810","https://openalex.org/W2170114044","https://openalex.org/W2174880987","https://openalex.org/W2189726121","https://openalex.org/W2271726308","https://openalex.org/W2548706052","https://openalex.org/W2614051918","https://openalex.org/W2744079636","https://openalex.org/W2751548610","https://openalex.org/W2993044117","https://openalex.org/W3098028118"],"related_works":["https://openalex.org/W2321824856","https://openalex.org/W2788895036","https://openalex.org/W6889933366","https://openalex.org/W2483108600","https://openalex.org/W4250330082","https://openalex.org/W4407631363","https://openalex.org/W6964992897","https://openalex.org/W6946455704","https://openalex.org/W7056745309","https://openalex.org/W6907502751"],"abstract_inverted_index":{"Einleitung:":[0],"Durch":[1],"Vorhofflimmern":[2],"(VHF)":[3],"bedingte":[4],"Schlaganf\u00e4lle":[5],"gehen":[6],"mit":[7,24,79,106,150,185,215,241,361,376,384],"einer":[8,102,113,265,385],"hohen":[9],"Morbidit\u00e4t":[10],"und":[11,29,39,55,93,110,119,172,233,285,322,339],"Mortalit\u00e4t":[12],"einher.":[13],"Eine":[14,379],"therapeutische":[15,287,381],"orale":[16],"Antikoagulation":[17,103,115,221,246,266,288,382],"mittels":[18],"Vitamin":[19],"K-Antagonisten":[20],"senkt":[21],"bei":[22,31,85,104,200,342,374],"Patienten":[23,48,105,126,137,156,184,195,203,214,240],"VHF":[25,108,147,151,158,187],"das":[26,398],"Schlaganfall-Risiko":[27],"signifikant":[28,360],"reduziert":[30],"Auftreten":[32],"eines":[33,58],"isch\u00e4mischen":[34,131],"Schlaganfalls":[35,60],"offenbar":[36],"den":[37,52,99,117,301],"Schlaganfall-Schweregrad":[38,118,341],"die":[40,50,111,120,199,218,244,263,306],"Kurzzeit-":[41],"Mortalit\u00e4t.":[42],"Methodik:":[43],"Es":[44,365],"wurden":[45,96],"retrospektiv":[46],"2390":[47,125],"analysiert,":[49],"in":[51,61,370],"Jahren":[53],"2003":[54],"2004":[56],"aufgrund":[57],"akuten":[59],"der":[62,65,183,340,362,371],"Neurologischen":[63],"Klinik":[64],"Charit\u00e9":[66],"station\u00e4r":[67,143],"behandelt":[68],"wurden.":[69],"Im":[70],"Jahr":[71],"2008":[72],"erfolgte":[73],"eine":[74,197,220,249,330],"postalische":[75],"Nachbefragung":[76],"aller":[77],"Schlaganfall-Patienten":[78,149,375],"VHF.":[80,378],"Der":[81],"durchschnittliche":[82],"Beobachtungszeitraum":[83],"lag":[84,207],"38":[86],"Monaten":[87],"(Spannbreite":[88],"0-68).":[89],"Anhand":[90],"von":[91,212],"uni-":[92],"multivariablen":[94],"Regressionsanalysen":[95],"Einflussfaktoren":[97],"auf":[98,116,262,300,397],"pr\u00e4station\u00e4ren":[100,114],"Erhalt":[101],"bekanntem":[107,186,216,242,377],"identifiziert":[109],"Bedeutung":[112],"Langzeit-Mortalit\u00e4t":[121],"untersucht.":[122],"Ergebnisse:":[123],"Von":[124],"erlitten":[127],"91,4%":[128],"(n=2185)":[129],"einen":[130],"Schlaganfall.":[132],"Bei":[133],"23,2%":[134],"(n=506)":[135],"dieser":[136,194],"wurde":[138],"pr\u00e4station\u00e4r":[139,219],"(n=334;":[140],"66,0%)":[141],"oder":[142],"(n=172;":[144],"34,0%)":[145],"ein":[146],"nachgewiesen.":[148],"waren":[152,223],"\u00e4lter":[153],"als":[154,239,297],"Schlaganfall-":[155,389],"ohne":[157],"(75,9":[159],"\u00b1":[160,164,226,230],"9,5":[161],"vs.":[162,170,228,237],"65,7":[163],"13,2":[165],"Jahre),":[166],"h\u00e4ufiger":[167,234],"weiblich":[168],"(57,1%":[169],"45,3%)":[171],"wiesen":[173],"mehr":[174],"kardiovaskul\u00e4re":[175],"Risikofaktoren":[176],"auf.":[177],"Gem\u00e4\u00df":[178],"geltenden":[179],"Leitlinien":[180],"h\u00e4tten":[181],"93,4%":[182],"oral":[188],"antikoaguliert":[189],"werden":[190],"sollen.":[191],"F\u00fcnfundsiebzig":[192],"(23,1%)":[193],"erhielten":[196],"Antikoagulation,":[198],"20":[201],"(6,2%)":[202],"im":[204],"therapeutischen":[205],"Bereich":[206],"(international":[208],"normalized":[209],"ratio":[210],"(INR)":[211],"2-3).":[213],"VHF,":[217,243],"erhielten,":[222,247],"j\u00fcnger":[224],"(74,7":[225],"7,1":[227],"77,3":[229],"9,1":[231],"Jahre)":[232],"m\u00e4nnlich":[235],"(52,0%":[236],"38,4%)":[238],"keine":[245],"w\u00e4hrend":[248],"vorherige":[250],"zerebrale":[251],"Isch\u00e4mie":[252],"vor":[253],"dem":[254],"zur":[255],"Aufnahme":[256,343],"f\u00fchrenden":[257],"Schlaganfall":[258],"keinen":[259,394],"signifikanten":[260,386,395],"Einfluss":[261,396],"Verschreibung":[264],"hatte.":[267],"Die":[268],"Faktoren":[269],"Patientenalter":[270,304],"(OR":[271,280,290],"1,02":[272],"[95%":[273,282,292,312,319,327,336,349,356],"CI":[274,283,293,313,320,328,337,350,357],"1,00-1,04]":[275],"pro":[276],"Jahr),":[277],"koronare":[278],"Herzkrankheit":[279],"1,51":[281],"1,01-2,26])":[284],"pr\u00e4station\u00e4re":[286,331,380],"(INR\u22652)":[289],"0,28":[291],"0,09-0,84])":[294],"erwiesen":[295],"sich":[296,367],"signifikante":[298],"Einflussgr\u00f6\u00dfen":[299],"Schlaganfall-Schweregrad.":[302],"Das":[303],"f\u00fcr":[305],"Altersgruppen":[307],"65-74":[308],"Jahre":[309,316,324],"(HR":[310,317,325,334,347,354],"3,11":[311],"1,47-6,59]),":[314],"75-84":[315],"4,65":[318],"2,26-9,57])":[321],"\u226585":[323],"11,1":[326],"4,90-25,1]),":[329],"antithrombotische":[332],"Medikation":[333],"1,85":[335],"1,21-2,82])":[338],"(NIHSS-Kategorie":[344],"6-15":[345],"Punkte":[346,353],"1,60":[348],"1,03-2,46]);":[351],">15":[352],"3,23":[355],"1,88-5,55])":[358],"korrelierten":[359],"\u00dcberlebenszeit.":[363],"Schlussfolgerung:":[364],"fanden":[366],"gravierende":[368],"Defizite":[369],"medikament\u00f6sen":[372],"Pr\u00e4vention":[373],"ging":[383],"Reduktion":[387],"des":[388],"Schwergrades":[390],"einher,":[391],"zeigte":[392],"jedoch":[393],"Langzeit-\u00dcberleben.":[399]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
