{"id":"https://openalex.org/W1739014274","doi":null,"title":"Total IgE as a serodiagnostic marker to aid murine fur mite detection.","display_name":"Total IgE as a serodiagnostic marker to aid murine fur mite detection.","publication_year":2012,"publication_date":"2012-03-01","ids":{"openalex":"https://openalex.org/W1739014274","mag":"1739014274","pmid":"https://pubmed.ncbi.nlm.nih.gov/22776120","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3314523"},"language":"en","primary_location":{"id":"pmid:22776120","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22776120","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Association for Laboratory Animal Science : JAALAS","raw_type":"Evaluation Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3314523/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043113881","display_name":"Gordon S. Roble","orcid":"https://orcid.org/0009-0007-5760-1930","observed_orcids":["https://orcid.org/0009-0007-5760-1930"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon S Roble","raw_affiliation_strings":["Tri-institutional Training Program in Laboratory Animal Medicine and Science, The Rockefeller University, and Weill Cornell Medical College, New York, New York, USA. gsr7@nyu.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tri-institutional Training Program in Laboratory Animal Medicine and Science, The Rockefeller University, and Weill Cornell Medical College, New York, New York, USA. gsr7@nyu.edu","institution_ids":["https://openalex.org/I4387153466","https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033898895","display_name":"W L Boteler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William Boteler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111580536","display_name":"Elyn Riedel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elyn Riedel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5060816278","display_name":"Neil S Lipman","orcid":"https://orcid.org/0000-0003-1258-2602","observed_orcids":["https://orcid.org/0000-0003-1258-2602"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neil S Lipman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5647,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.81053905,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"51","issue":"2","first_page":"199","last_page":"208"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12116","display_name":"Dermatological diseases and infestations","score":0.8285999894142151,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12116","display_name":"Dermatological diseases and infestations","score":0.8285999894142151,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":0.03550000116229057,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12361","display_name":"Study of Mite Species","score":0.01979999989271164,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/total-serum-ige","display_name":"total IgE","score":0.9520000219345093},{"id":"https://openalex.org/keywords/fur-mites","display_name":"fur mites","score":0.7239999771118164},{"id":"https://openalex.org/keywords/ivermectin-treatment","display_name":"ivermectin treatment","score":0.8730000257492065},{"id":"https://openalex.org/keywords/strain-differences","display_name":"strain differences","score":0.4180000126361847},{"id":"https://openalex.org/keywords/swiss-webster-mice","display_name":"Swiss Webster mice","score":0.6729999780654907},{"id":"https://openalex.org/keywords/c57bl-6-mice","display_name":"C57BL/6 mice","score":0.9929999709129333},{"id":"https://openalex.org/keywords/syphacia-obvelata","display_name":"Syphacia obvelata","score":0.8169999718666077},{"id":"https://openalex.org/keywords/aspiculuris-tetraptera","display_name":"Aspiculuris tetraptera","score":0.9879999756813049}],"concepts":[{"id":"https://openalex.org/C2777499811","wikidata":"https://www.wikidata.org/wiki/Q415178","display_name":"Ivermectin","level":2,"score":0.7905540466308594},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.745542585849762},{"id":"https://openalex.org/C2779711295","wikidata":"https://www.wikidata.org/wiki/Q2441993","display_name":"Mite","level":2,"score":0.7062970399856567},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.6209168434143066},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5787485837936401},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.5590009093284607},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5264713764190674},{"id":"https://openalex.org/C2776451879","wikidata":"https://www.wikidata.org/wiki/Q1292038","display_name":"Infestation","level":2,"score":0.41364043951034546},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27044788002967834},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2170168161392212},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.08381181955337524},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000909","descriptor_name":"Antibodies, Helminth","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000977","descriptor_name":"Antiparasitic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006197","descriptor_name":"Hair","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007559","descriptor_name":"Ivermectin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008924","descriptor_name":"Mite Infestations","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008924","descriptor_name":"Mite Infestations","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008924","descriptor_name":"Mite Infestations","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008924","descriptor_name":"Mite Infestations","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D008925","descriptor_name":"Mites","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010123","descriptor_name":"Oxyuriasis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010123","descriptor_name":"Oxyuriasis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010123","descriptor_name":"Oxyuriasis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010123","descriptor_name":"Oxyuriasis","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D010124","descriptor_name":"Oxyuroidea","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010124","descriptor_name":"Oxyuroidea","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012376","descriptor_name":"Rodent Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012376","descriptor_name":"Rodent Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012376","descriptor_name":"Rodent Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012698","descriptor_name":"Serologic Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012698","descriptor_name":"Serologic Tests","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056810","descriptor_name":"Acaricides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:22776120","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22776120","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Association for Laboratory Animal Science : JAALAS","raw_type":"Evaluation Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:3314523","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3314523/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Assoc Lab Anim Sci","raw_type":"Text"},{"id":"mag:1739014274","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22776120","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3314523","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3314523/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Assoc Lab Anim Sci","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W92771133","https://openalex.org/W119231048","https://openalex.org/W156556950","https://openalex.org/W1571914910","https://openalex.org/W1604407827","https://openalex.org/W1732660062","https://openalex.org/W1964236572","https://openalex.org/W1965348715","https://openalex.org/W1976993756","https://openalex.org/W1981527452","https://openalex.org/W1984742453","https://openalex.org/W1991589959","https://openalex.org/W2008795839","https://openalex.org/W2021233744","https://openalex.org/W2031593710","https://openalex.org/W2049389418","https://openalex.org/W2050458928","https://openalex.org/W2075651656","https://openalex.org/W2078781783","https://openalex.org/W2080923384","https://openalex.org/W2101517152","https://openalex.org/W2104960492","https://openalex.org/W2105174331","https://openalex.org/W2115606291","https://openalex.org/W2132118265","https://openalex.org/W2147595228","https://openalex.org/W2148676990","https://openalex.org/W2152609359","https://openalex.org/W2164561581","https://openalex.org/W2331668470","https://openalex.org/W2398538414","https://openalex.org/W2407644812","https://openalex.org/W2418705843","https://openalex.org/W2418827246","https://openalex.org/W2991926533","https://openalex.org/W2997733745","https://openalex.org/W4313313464"],"related_works":["https://openalex.org/W1964236572","https://openalex.org/W1981527452","https://openalex.org/W1969653466","https://openalex.org/W119231048","https://openalex.org/W3040283507","https://openalex.org/W1732660062","https://openalex.org/W2010889494","https://openalex.org/W2393281075","https://openalex.org/W2133938901","https://openalex.org/W2558295928"],"abstract_inverted_index":{"Mites":[0,20],"of":[1,16,27,142,149],"3":[2],"genera-Myobia,":[3],"Myocoptes,":[4],"and":[5,38,48,81,91,100,109,131,134,178,221],"Radfordia":[6],"-continue":[7],"to":[8,63,116,124,188],"plague":[9],"laboratory":[10],"mouse":[11],"facilities,":[12],"even":[13],"with":[14,106,201],"use":[15],"stringent":[17],"biosecurity":[18],"measures.":[19],"often":[21],"spread":[22],"before":[23],"diagnosis,":[24],"predominantly":[25],"because":[26,227],"detection":[28,31,47],"difficulty.":[29],"Current":[30],"methods":[32],"have":[33],"suboptimal":[34],"sensitivity,":[35],"are":[36,39],"time-consuming,":[37],"costly.":[40],"A":[41,147],"sensitive":[42],"serodiagnostic":[43,61],"technique":[44],"would":[45],"facilitate":[46],"ease":[49],"workload.":[50],"We":[51,236],"evaluated":[52],"whether":[53],"total":[54,69,198,204,216,233,240],"IgE":[55,70,120,128,184,205,217,234,241],"increases":[56,118,214],"could":[57],"serve":[58],"as":[59],"a":[60,143,166,192],"marker":[62],"identify":[64],"mite":[65,77,228],"infestations.":[66],"Variables":[67],"affecting":[68],"levels":[71,121,130,206,242],"including":[72],"infestation":[73],"duration,":[74],"sex,":[75],"age,":[76],"species,":[78],"soiled-bedding":[79],"exposure,":[80],"ivermectin":[82,202],"treatment":[83],"were":[84,94,137,173],"investigated":[85],"in":[86,119,183,197,215,218,244],"Swiss":[87,101,155,219],"Webster":[88,102,156,220],"mice.":[89],"Strain-":[90],"pinworm-associated":[92],"effects":[93],"examined":[95],"by":[96,165],"using":[97,239],"C57BL/6":[98,222],"mice":[99,103,223],"dually":[104],"infested":[105],"Syphacia":[107],"obvelata":[108],"Aspiculuris":[110],"tetraptera,":[111],"respectively.":[112],"Mite":[113],"infestations":[114,229],"led":[115],"significant":[117,195],"within":[122,207],"2":[123,208],"4":[125],"wk.":[126,209],"Total":[127],"threshold":[129,148],"corresponding":[132],"sensitivity":[133],"specificity":[135],"values":[136,158],"determined":[138],"along":[139],"the":[140],"continuum":[141],"receiver-operating":[144],"characteristic":[145],"curve.":[146],"81":[150],"ng/mL":[151],"was":[152],"chosen":[153],"for":[154],"mice;":[157],"above":[159],"this":[160],"point":[161],"should":[162],"trigger":[163],"screening":[164],"secondary,":[167],"more":[168],"specific":[169],"method.":[170],"Sex-associated":[171],"differences":[172],"not":[174],"significant.":[175],"Age,":[176],"strain,":[177],"infecting":[179],"parasite":[180],"caused":[181],"variability":[182],"responses.":[185],"Mice":[186],"exposed":[187],"soiled":[189],"bedding":[190],"showed":[191],"delayed":[193],"yet":[194],"increase":[196],"IgE.":[199],"Treatment":[200],"reduced":[203],"Our":[210],"data":[211],"suggest":[212],"that":[213,238],"warrant":[224],"investigation,":[225],"especially":[226],"can":[230],"rapidly":[231],"elevate":[232],"levels.":[235],"propose":[237],"routinely":[243],"serologic":[245],"panels":[246],"will":[247],"enhance":[248],"biosecurity.":[249]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}