{"id":"https://openalex.org/W17349103","doi":null,"title":"\u0421irculating tumour cells: molecular properties and anti-cancer treatment monitoring","display_name":"\u0421irculating tumour cells: molecular properties and anti-cancer treatment monitoring","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W17349103","mag":"17349103"},"language":"en","primary_location":{"id":"mag:17349103","doi":null,"is_oa":false,"landing_page_url":"https://cyberleninka.ru/article/n/tsirkuliruyuschie-rakovye-kletki-molekulyarnaya-harakteristika-i-monitoring-lecheniya-raka/pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401404","display_name":"CyberLeninK (CyberLeninka)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430 \u041a\u0430\u0437\u0430\u0445\u0441\u0442\u0430\u043d\u0430","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087550958","display_name":"Abay K. Baigenzhin","orcid":"https://orcid.org/0000-0002-7703-5004","observed_orcids":["https://orcid.org/0000-0002-7703-5004"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u0410bay Baigenzhin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7703-5004","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028492877","display_name":"Galiya Shaimardanova","orcid":"https://orcid.org/0000-0002-1414-8618","observed_orcids":["https://orcid.org/0000-0002-1414-8618"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Galiya Shaimardanova","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1414-8618","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101678876","display_name":"\u041d. \u0412. \u041f\u043e\u043f\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0002-3241-6460","observed_orcids":["https://orcid.org/0000-0002-3241-6460"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u041d. \u0412. \u041f\u043e\u043f\u043e\u0432\u0430","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3241-6460","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087441452","display_name":"\u0411. \u0422. \u0416\u0443\u0441\u0438\u043f\u043e\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u0411. \u0422. \u0416\u0443\u0441\u0438\u043f\u043e\u0432\u0430","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5026469154","display_name":"Gulziya Ismailova","orcid":"https://orcid.org/0000-0002-7461-4190","observed_orcids":["https://orcid.org/0000-0002-7461-4190"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gulziya Ismailova","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7461-4190","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00091254,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":92},"biblio":{"volume":"4","issue":"30","first_page":"9","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.7480000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.7480000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.23119999468326569,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circulating-tumor-cells","display_name":"circulating tumor cells","score":0.8880000114440918},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.8880000114440918},{"id":"https://openalex.org/keywords/mesenchymal-epithelial-transition","display_name":"mesenchymal-epithelial transition","score":0.9900000095367432},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.6449999809265137},{"id":"https://openalex.org/keywords/measurable-residual-disease","display_name":"minimal residual disease","score":0.8709999918937683},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.7239999771118164},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.6980000138282776},{"id":"https://openalex.org/keywords/molecular-markers","display_name":"molecular markers","score":0.3580000102519989}],"concepts":[{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.8600019216537476},{"id":"https://openalex.org/C2779823535","wikidata":"https://www.wikidata.org/wiki/Q6865356","display_name":"Minimal residual disease","level":3,"score":0.6688557267189026},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5811640620231628},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5455025434494019},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.5275696516036987},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.527214765548706},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.48792168498039246},{"id":"https://openalex.org/C2779529041","wikidata":"https://www.wikidata.org/wiki/Q22349364","display_name":"Liquid biopsy","level":3,"score":0.48082149028778076},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4672422707080841},{"id":"https://openalex.org/C55427017","wikidata":"https://www.wikidata.org/wiki/Q1638475","display_name":"Cancer stem cell","level":3,"score":0.4143560528755188},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3454025685787201},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34350860118865967},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3305319845676422},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24281704425811768},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.1108439564704895}],"mesh":[],"locations_count":2,"locations":[{"id":"mag:17349103","doi":null,"is_oa":false,"landing_page_url":"https://cyberleninka.ru/article/n/tsirkuliruyuschie-rakovye-kletki-molekulyarnaya-harakteristika-i-monitoring-lecheniya-raka/pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401404","display_name":"CyberLeninK (CyberLeninka)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430 \u041a\u0430\u0437\u0430\u0445\u0441\u0442\u0430\u043d\u0430","raw_type":null},{"id":"mag:2493390573","doi":null,"is_oa":false,"landing_page_url":"https://www.clinmedkaz.org/download/irculating-tumour-cells-molecular-properties-and-anti-cancer-treatment-monitoring-8624.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4210196841","display_name":"Journal of Clinical Medicine of Kazakhstan","issn_l":"1812-2892","issn":["1812-2892","2313-1519"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Clinical Medicine of Kazakhstan","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W2001453669","https://openalex.org/W2017583911","https://openalex.org/W2031417373","https://openalex.org/W2037547770","https://openalex.org/W2050547995","https://openalex.org/W2050827942","https://openalex.org/W2051572649","https://openalex.org/W2063140987","https://openalex.org/W2110141569","https://openalex.org/W2139799027","https://openalex.org/W2146678830","https://openalex.org/W2151509613","https://openalex.org/W2152723841","https://openalex.org/W2171298396"],"related_works":["https://openalex.org/W2493390573","https://openalex.org/W186778522","https://openalex.org/W3217081290","https://openalex.org/W4400123941","https://openalex.org/W2020737703","https://openalex.org/W3040887185","https://openalex.org/W2116306598","https://openalex.org/W3031651780","https://openalex.org/W2794015436","https://openalex.org/W2769331293"],"abstract_inverted_index":{"Existence":[0],"of":[1,8,16,28,47,61,66,78,88,94,109,118,133,172,182,191,201],"circulating":[2,119,159],"tumor":[3,135],"cells":[4,18,51,121,161],"(CTCs)":[5],"in":[6,64,86,92],"blood":[7,22],"cancer":[9,17,29,95,160],"patients,":[10],"testifi":[11,34],"es":[12,35],"about":[13],"a":[14],"dissemination":[15],"to":[19,36,103,144,154],"the":[20,25,54,76,105,114,125,139,150,163,196],"peripheral":[21],"stream,":[23],"on":[24,157,195],"earliest":[26],"stages":[27],"development":[30],"and":[31,58,82,107,141,149,179],"very":[32],"often":[33],"an":[37],"adverse":[38],"clinical":[39,173],"current,":[40],"especially":[41],"it":[42],"is":[43],"connected":[44],"with":[45,71],"formation":[46,87],"metastases.":[48],"Besides,":[49],"these":[50],"can":[52],"represent":[53],"minimum":[55,186],"residual":[56,187],"disease":[57],"quantitative":[59],"monitoring":[60,181],"CTCs":[62],"level":[63],"time":[65],"anti-cancer":[67,155],"treatment":[68,156],"provides":[69],"researchers":[70],"valuable":[72],"information.":[73],"For":[74],"today":[75],"role":[77],"epithelial-to-mesenchymal":[79],"transit":[80,84],"(EMT)":[81],"mesenchymal-to-epithelial":[83],"(MET)":[85],"various":[89],"subpopulations":[90],"CTCs,":[91,183],"expansion":[93],"aggressive":[96],"properties.":[97],"In":[98],"this":[99],"article":[100],"we":[101],"want":[102],"prove":[104],"purpose":[106],"problems":[108],"our":[110],"scientifi":[111],"c":[112],"research":[113],"cytological":[115,198],"molecular":[116,180,199],"analysis":[117,200],"tumour":[120],"have":[122],"isolated":[123],"by":[124,131,162,189],"size":[126,132],"dependent":[127],"ISET":[128],"technology":[129],"(Isolation":[130],"epithelial":[134],"cells).":[136],"To":[137,170],"study":[138,171],"cyto-morphological":[140],"immunological":[142,178],"characteristic,":[143],"identify":[145],"targeted":[146,193],"therapy":[147],"markers":[148],"metastatic":[151],"response":[152],"predictors":[153],"viable":[158],"RT-PCR":[164],"method":[165],"(real-time":[166],"polymerase":[167],"chained":[168],"action).":[169],"profi":[174],"t":[175],"from":[176],"quantitative,":[177],"for":[184],"elimination":[185],"disease,":[188],"application":[190],"individual":[192],"therapy,":[194],"basis":[197],"CTCs.":[202]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}