{"id":"https://openalex.org/W1718878505","doi":"https://doi.org/10.1128/iai.56.2.331-335.1988","title":"Frequency of fimbriation of nontypable Haemophilus influenzae and its ability to adhere to chinchilla and human respiratory epithelium","display_name":"Frequency of fimbriation of nontypable Haemophilus influenzae and its ability to adhere to chinchilla and human respiratory epithelium","publication_year":1988,"publication_date":"1988-02-01","ids":{"openalex":"https://openalex.org/W1718878505","doi":"https://doi.org/10.1128/iai.56.2.331-335.1988","mag":"1718878505","pmid":"https://pubmed.ncbi.nlm.nih.gov/2892792","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/259284"},"language":"en","primary_location":{"id":"doi:10.1128/iai.56.2.331-335.1988","doi":"https://doi.org/10.1128/iai.56.2.331-335.1988","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.56.2.331-335.1988","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/259284","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068983530","display_name":"Lauren O. Bakaletz","orcid":"https://orcid.org/0000-0002-0017-1710","observed_orcids":["https://orcid.org/0000-0002-0017-1710"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L O Bakaletz","raw_affiliation_strings":["Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077731009","display_name":"B M Tallan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B M Tallan","raw_affiliation_strings":["Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007716980","display_name":"Toni M. Hoepf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T Hoepf","raw_affiliation_strings":["Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029344762","display_name":"Thomas F. DeMaria","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T F DeMaria","raw_affiliation_strings":["Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003560729","display_name":"Herbert G. Birck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H G Birck","raw_affiliation_strings":["Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001942999","display_name":"DAVID J. LIM","orcid":"https://orcid.org/0000-0002-2837-0973","observed_orcids":["https://orcid.org/0000-0002-2837-0973"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D J Lim","raw_affiliation_strings":["Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240","Academic Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Ohio State University College of Medicine, Columbus 43210-1240","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Academic Institute","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I52357470"],"apc_list":null,"apc_paid":null,"fwci":2.8217,"has_fulltext":false,"cited_by_count":110,"citation_normalized_percentile":{"value":0.88616071,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"56","issue":"2","first_page":"331","last_page":"335"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.6797000169754028,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.6797000169754028,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.14650000631809235,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.09030000120401382,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nontypeable-haemophilus-influenzae","display_name":"nontypeable Haemophilus influenzae","score":0.9829999804496765},{"id":"https://openalex.org/keywords/bacterial-fimbriae","display_name":"bacterial fimbriae","score":0.9190000295639038},{"id":"https://openalex.org/keywords/bacterial-adhesion","display_name":"bacterial adhesion","score":0.746999979019165},{"id":"https://openalex.org/keywords/middle-ear-effusion","display_name":"middle ear effusion","score":0.8009999990463257},{"id":"https://openalex.org/keywords/nasopharyngeal-isolates","display_name":"nasopharyngeal isolates","score":0.9769999980926514},{"id":"https://openalex.org/keywords/hemagglutination","display_name":"hemagglutination","score":0.8220000267028809},{"id":"https://openalex.org/keywords/bacterial-appendages","display_name":"bacterial appendages","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C2776925733","wikidata":"https://www.wikidata.org/wiki/Q1141979","display_name":"Haemophilus influenzae","level":3,"score":0.8240377902984619},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8238348960876465},{"id":"https://openalex.org/C39103817","wikidata":"https://www.wikidata.org/wiki/Q1810775","display_name":"Fimbria","level":4,"score":0.8160743713378906},{"id":"https://openalex.org/C2779415040","wikidata":"https://www.wikidata.org/wiki/Q192930","display_name":"Chinchilla","level":2,"score":0.8125872015953064},{"id":"https://openalex.org/C2777154767","wikidata":"https://www.wikidata.org/wiki/Q142666","display_name":"Pasteurellaceae","level":4,"score":0.7265300750732422},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6583162546157837},{"id":"https://openalex.org/C174832134","wikidata":"https://www.wikidata.org/wiki/Q934786","display_name":"Pilus","level":4,"score":0.6272711753845215},{"id":"https://openalex.org/C2776439223","wikidata":"https://www.wikidata.org/wiki/Q480700","display_name":"Otitis","level":2,"score":0.5387289524078369},{"id":"https://openalex.org/C34343649","wikidata":"https://www.wikidata.org/wiki/Q1548862","display_name":"Hemagglutination","level":3,"score":0.5069380402565002},{"id":"https://openalex.org/C2776402342","wikidata":"https://www.wikidata.org/wiki/Q311275","display_name":"Haemophilus","level":3,"score":0.4100266098976135},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2549057900905609},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22110900282859802},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.1593572199344635},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.15512272715568542},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.11995413899421692},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06908828020095825},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001422","descriptor_name":"Bacterial Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002682","descriptor_name":"Chinchilla","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006193","descriptor_name":"Haemophilus influenzae","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D006193","descriptor_name":"Haemophilus influenzae","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D006384","descriptor_name":"Hemagglutination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010033","descriptor_name":"Otitis Media","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010614","descriptor_name":"Pharynx","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010861","descriptor_name":"Fimbriae, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/iai.56.2.331-335.1988","doi":"https://doi.org/10.1128/iai.56.2.331-335.1988","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.56.2.331-335.1988","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:259284","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/259284","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:2892792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2892792","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:259284","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/259284","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/14","score":0.5400000214576721,"display_name":"Life below water"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2947625700","display_name":null,"funder_award_id":"NS 08854","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1820746812","https://openalex.org/W1842954398","https://openalex.org/W1843873636","https://openalex.org/W1847173828","https://openalex.org/W1961485906","https://openalex.org/W1980161619","https://openalex.org/W1992588950","https://openalex.org/W2019266402","https://openalex.org/W2045616416","https://openalex.org/W2072424528","https://openalex.org/W2103888716","https://openalex.org/W2104538847","https://openalex.org/W2133188879","https://openalex.org/W2149959566","https://openalex.org/W2151466779","https://openalex.org/W2159471297","https://openalex.org/W2317363948","https://openalex.org/W2410606762"],"related_works":["https://openalex.org/W1942885837","https://openalex.org/W2154878820","https://openalex.org/W2164066234","https://openalex.org/W2149959566","https://openalex.org/W2072866334","https://openalex.org/W2412943183","https://openalex.org/W1902158600","https://openalex.org/W2002761368","https://openalex.org/W1842954398","https://openalex.org/W2155316934"],"abstract_inverted_index":{"To":[0],"date,":[1],"we":[2],"have":[3,21],"examined":[4],"nearly":[5],"60":[6],"clinical":[7],"isolates":[8,84],"of":[9,29,67,74,97,111,119,123,128,157,165],"nontypable":[10],"Haemophilus":[11],"influenzae":[12,148],"(26":[13],"nasopharyngeal,":[14],"33":[15],"from":[16,37,141],"middle":[17],"ear":[18],"effusions)":[19],"and":[20,72,92,155],"found":[22],"that":[23],"100%":[24],"were":[25,53],"fimbriated.":[26],"The":[27,107],"percentage":[28],"cells":[30,91],"bearing":[31],"fimbriae":[32,44,75],"within":[33],"each":[34],"isolate":[35,104],"varied":[36],"less":[38],"than":[39],"10":[40],"to":[41,56,87,100,137,153,159],"100%,":[42],"with":[43,116,163],"being":[45],"either":[46,117],"peritrichous":[47],"or":[48,109,126],"bipolar":[49],"in":[50,59,69,131,149],"distribution.":[51],"Fimbriae":[52],"approximately":[54],"2.4":[55],"3.6":[57],"nm":[58],"width;":[60],"however,":[61],"there":[62],"was":[63,105],"a":[64],"high":[65],"degree":[66,99,110,164],"variability":[68],"both":[70,88],"length":[71],"number":[73],"per":[76],"individual":[77],"bacterial":[78],"cell":[79],"among":[80],"these":[81],"isolates.":[82],"All":[83],"tested":[85],"adhered":[86],"human":[89],"oropharyngeal":[90],"chinchilla":[93],"tracheal":[94],"epithelium":[95],"regardless":[96],"the":[98,102,132,151],"which":[101,150],"particular":[103],"fimbriate.":[106],"level":[108],"fimbriation":[112],"did":[113],"not":[114],"correlate":[115],"site":[118],"isolation,":[120],"biotype,":[121],"strength":[122,156],"hemagglutination":[124],"reaction,":[125],"type":[127,145],"effusion":[129],"present":[130],"ear.":[133],"These":[134],"appendages":[135],"appear":[136],"be":[138],"quite":[139],"different":[140],"those":[142],"described":[143],"for":[144],"b":[146],"H.":[147],"ability":[152,158],"adhere":[154],"hemagglutinate":[160],"correlated":[161],"strongly":[162],"fimbriation.":[166]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}