{"id":"https://openalex.org/W171675974","doi":null,"title":"Dengue vaccines: problems and prospects.","display_name":"Dengue vaccines: problems and prospects.","publication_year":2005,"publication_date":"2005-05-01","ids":{"openalex":"https://openalex.org/W171675974","mag":"171675974","pmid":"https://pubmed.ncbi.nlm.nih.gov/15937367"},"language":"en","primary_location":{"id":"pmid:15937367","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15937367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of medical research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051246987","display_name":"U. C. Chaturvedi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I280994","display_name":"King George's Medical University","ror":"https://ror.org/00gvw6327","country_code":"IN","type":"education","lineage":["https://openalex.org/I280994"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"U C Chaturvedi","raw_affiliation_strings":["K.G. Medical University, Lucknow, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"K.G. Medical University, Lucknow, India","institution_ids":["https://openalex.org/I280994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101859541","display_name":"Richa Shrivastava","orcid":"https://orcid.org/0000-0002-8322-926X","observed_orcids":["https://orcid.org/0000-0002-8322-926X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richa Shrivastava","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5059177991","display_name":"Rachna Nagar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rachna Nagar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.8489,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.97754417,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"121","issue":"5","first_page":"639","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dengue-vaccine","display_name":"dengue vaccine","score":0.9670000076293945},{"id":"https://openalex.org/keywords/dengue-virus","display_name":"dengue virus","score":0.8999999761581421},{"id":"https://openalex.org/keywords/dengue-hemorrhagic-fever","display_name":"dengue hemorrhagic fever","score":0.9139999747276306},{"id":"https://openalex.org/keywords/vaccine-development","display_name":"vaccine development","score":0.8610000014305115},{"id":"https://openalex.org/keywords/vaccine-safety","display_name":"vaccine safety","score":0.6669999957084656},{"id":"https://openalex.org/keywords/vaccine-formulation","display_name":"vaccine formulation","score":0.8349999785423279},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.6549999713897705},{"id":"https://openalex.org/keywords/vaccine-efficacy","display_name":"vaccine efficacy","score":0.6830000281333923},{"id":"https://openalex.org/keywords/vaccine-candidate","display_name":"vaccine candidate","score":0.5400000214576721},{"id":"https://openalex.org/keywords/disease-burden","display_name":"disease burden","score":0.42399999499320984}],"concepts":[{"id":"https://openalex.org/C533803919","wikidata":"https://www.wikidata.org/wiki/Q30953","display_name":"Dengue fever","level":2,"score":0.9299783706665039},{"id":"https://openalex.org/C2779308166","wikidata":"https://www.wikidata.org/wiki/Q18388297","display_name":"Dengue vaccine","level":4,"score":0.9250470399856567},{"id":"https://openalex.org/C2779635636","wikidata":"https://www.wikidata.org/wiki/Q476209","display_name":"Dengue virus","level":3,"score":0.6505218744277954},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5481264591217041},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.49530354142189026},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4504948854446411},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.41816824674606323},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4161185026168823},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.40520644187927246},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003715","descriptor_name":"Dengue","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003715","descriptor_name":"Dengue","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003715","descriptor_name":"Dengue","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D003716","descriptor_name":"Dengue Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014614","descriptor_name":"Vaccines, Synthetic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014765","descriptor_name":"Viral Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015164","descriptor_name":"Vaccines, Inactivated","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:15937367","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15937367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of medical research","raw_type":"Journal Article"},{"id":"mag:171675974","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15937367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:2130592278","doi":null,"is_oa":false,"landing_page_url":"https://icmr.nic.in/ijmr/2005/May/0501.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":111,"referenced_works":["https://openalex.org/W164843018","https://openalex.org/W173331421","https://openalex.org/W299874186","https://openalex.org/W593342237","https://openalex.org/W1497030000","https://openalex.org/W1503730558","https://openalex.org/W1518659327","https://openalex.org/W1519382904","https://openalex.org/W1568901436","https://openalex.org/W1651247278","https://openalex.org/W1783145699","https://openalex.org/W1943434922","https://openalex.org/W1961261478","https://openalex.org/W1972097918","https://openalex.org/W1973924100","https://openalex.org/W1975258541","https://openalex.org/W1977086731","https://openalex.org/W1981052336","https://openalex.org/W1981895261","https://openalex.org/W1984986192","https://openalex.org/W1990130249","https://openalex.org/W2000363784","https://openalex.org/W2001811622","https://openalex.org/W2003627888","https://openalex.org/W2007014532","https://openalex.org/W2009760265","https://openalex.org/W2012107788","https://openalex.org/W2016379107","https://openalex.org/W2021577176","https://openalex.org/W2023687052","https://openalex.org/W2025655999","https://openalex.org/W2038433611","https://openalex.org/W2046357398","https://openalex.org/W2047448202","https://openalex.org/W2049127119","https://openalex.org/W2049280865","https://openalex.org/W2053306858","https://openalex.org/W2055227287","https://openalex.org/W2059763682","https://openalex.org/W2061625361","https://openalex.org/W2062595146","https://openalex.org/W2066567935","https://openalex.org/W2067802866","https://openalex.org/W2070337065","https://openalex.org/W2070603406","https://openalex.org/W2071603444","https://openalex.org/W2072617418","https://openalex.org/W2077157264","https://openalex.org/W2077295427","https://openalex.org/W2080257067","https://openalex.org/W2081800156","https://openalex.org/W2086936085","https://openalex.org/W2091651594","https://openalex.org/W2094066274","https://openalex.org/W2097617494","https://openalex.org/W2098907233","https://openalex.org/W2101407512","https://openalex.org/W2109947713","https://openalex.org/W2110478164","https://openalex.org/W2110628545","https://openalex.org/W2113255200","https://openalex.org/W2113583073","https://openalex.org/W2116806886","https://openalex.org/W2118726943","https://openalex.org/W2120501913","https://openalex.org/W2122797450","https://openalex.org/W2124109048","https://openalex.org/W2128789431","https://openalex.org/W2129010749","https://openalex.org/W2129669946","https://openalex.org/W2131377273","https://openalex.org/W2131540833","https://openalex.org/W2131753358","https://openalex.org/W2133166266","https://openalex.org/W2140122307","https://openalex.org/W2143969673","https://openalex.org/W2148102134","https://openalex.org/W2152819826","https://openalex.org/W2153835325","https://openalex.org/W2154248797","https://openalex.org/W2155244918","https://openalex.org/W2155467132","https://openalex.org/W2155660565","https://openalex.org/W2156915564","https://openalex.org/W2158248629","https://openalex.org/W2158483704","https://openalex.org/W2162000792","https://openalex.org/W2162218978","https://openalex.org/W2163553879","https://openalex.org/W2163600402","https://openalex.org/W2166808031","https://openalex.org/W2169898619","https://openalex.org/W2171318474","https://openalex.org/W2171834193","https://openalex.org/W2186028729","https://openalex.org/W2225630451","https://openalex.org/W2237753678","https://openalex.org/W2300098702","https://openalex.org/W2307248919","https://openalex.org/W2395392134","https://openalex.org/W2410840420","https://openalex.org/W2412543431","https://openalex.org/W2416375010","https://openalex.org/W2418024225","https://openalex.org/W2429419415","https://openalex.org/W2469413391","https://openalex.org/W2496299159","https://openalex.org/W2496876820","https://openalex.org/W2509051160","https://openalex.org/W2749102845","https://openalex.org/W4297832232"],"related_works":["https://openalex.org/W2130592278","https://openalex.org/W3028897188","https://openalex.org/W2056863055","https://openalex.org/W2132858776","https://openalex.org/W2158105592","https://openalex.org/W2064516587","https://openalex.org/W2125601278","https://openalex.org/W4322718829","https://openalex.org/W7099431943","https://openalex.org/W1992083724"],"abstract_inverted_index":{"The":[0,39,132],"extent":[1],"of":[2,24,46,51,54,78,83,89,116,136,138],"cumulative":[3],"disease":[4,30],"burden":[5],"caused":[6],"by":[7],"dengue":[8,47,84,96,107],"virus":[9],"has":[10],"attained":[11],"an":[12],"unprecedented":[13],"level":[14],"in":[15,21,41,63,69,106,148,156],"recent":[16],"times":[17],"with":[18],"sharp":[19],"increase":[20],"the":[22,44,58,64,76,100,126,139,153],"size":[23],"human":[25,149],"population":[26],"at":[27],"risk.":[28],"Dengue":[29],"presents":[31],"highly":[32],"complex":[33],"medical,":[34],"economic":[35],"and":[36,61,66,87,134,146,161],"ecologic":[37],"problems.":[38],"surge":[40],"publications":[42],"on":[43],"development":[45],"vaccines,":[48,128],"taking":[49],"advantage":[50],"new":[52,117,140],"generation":[53],"biotechnology":[55],"techniques":[56,123],"indicates":[57],"profound":[59],"interest":[60],"urgency":[62],"scientific":[65],"medical":[67],"communities":[68],"combating":[70],"this":[71],"disease.":[72],"This":[73],"review":[74],"summarizes":[75],"importance":[77],"critical":[79],"subjects":[80],"like":[81],"pathogenesis":[82],"haemorrhagic":[85],"fever":[86],"inadequacy":[88],"animal":[90],"model":[91],"that":[92],"have":[93,129,143,164],"adversely":[94],"affected":[95],"vaccine":[97,108,141,157,159,162],"development.":[98],"Further,":[99],"remarkable":[101],"progresses":[102],"so":[103],"far":[104],"made":[105],"research":[109],"not":[110],"only":[111],"employing":[112],"a":[113],"diverse":[114],"range":[115],"strategies":[118],"but":[119],"also":[120],"re-using":[121],"old":[122],"to":[124],"improve":[125],"existing":[127],"been":[130,144,165],"presented.":[131],"efficacy":[133],"safety":[135,160],"some":[137],"candidates":[142],"evaluated":[145],"proven":[147],"preclinical/clinical":[150],"trials.":[151],"Besides":[152],"technical":[154],"advancement":[155],"development,":[158],"formulation":[163],"examined.":[166]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
