{"id":"https://openalex.org/W1710400459","doi":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","title":"\u03b2-Cell failure in type 2 diabetes","display_name":"\u03b2-Cell failure in type 2 diabetes","publication_year":2011,"publication_date":"2011-01-21","ids":{"openalex":"https://openalex.org/W1710400459","doi":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","mag":"1710400459","pmid":"https://pubmed.ncbi.nlm.nih.gov/24843466","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4015541"},"language":"en","primary_location":{"id":"doi:10.1111/j.2040-1124.2010.00094.x","doi":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.2040-1124.2010.00094.x","source":{"id":"https://openalex.org/S107365432","display_name":"Journal of Diabetes Investigation","issn_l":"2040-1116","issn":["2040-1116","2040-1124"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310322041","host_organization_name":"Asian Association for the Study of Diabetes","host_organization_lineage":["https://openalex.org/P4310322041"],"host_organization_lineage_names":["Asian Association for the Study of Diabetes"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Diabetes Investigation","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.2040-1124.2010.00094.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017696201","display_name":"Gil Leibowitz","orcid":"https://orcid.org/0000-0002-6915-4361","observed_orcids":["https://orcid.org/0000-0002-6915-4361"]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]},{"id":"https://openalex.org/I2799899409","display_name":"Hadassah Medical Center","ror":"https://ror.org/01cqmqj90","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799899409"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Gil Leibowitz","raw_affiliation_strings":["Endocrine Services, Department of Medicine, Hebrew University Hadassah Medical Center, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Services, Department of Medicine, Hebrew University Hadassah Medical Center, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160","https://openalex.org/I2799899409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110124347","display_name":"Nurit Kaiser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]},{"id":"https://openalex.org/I2799899409","display_name":"Hadassah Medical Center","ror":"https://ror.org/01cqmqj90","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799899409"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Nurit Kaiser","raw_affiliation_strings":["Endocrine Services, Department of Medicine, Hebrew University Hadassah Medical Center, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Services, Department of Medicine, Hebrew University Hadassah Medical Center, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160","https://openalex.org/I2799899409"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076271317","display_name":"Erol Cerasi","orcid":"https://orcid.org/0000-0002-8234-3618","observed_orcids":["https://orcid.org/0000-0002-8234-3618"]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]},{"id":"https://openalex.org/I2799899409","display_name":"Hadassah Medical Center","ror":"https://ror.org/01cqmqj90","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799899409"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Erol Cerasi","raw_affiliation_strings":["Endocrine Services, Department of Medicine, Hebrew University Hadassah Medical Center, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Services, Department of Medicine, Hebrew University Hadassah Medical Center, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160","https://openalex.org/I2799899409"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5076271317"],"corresponding_institution_ids":["https://openalex.org/I197251160","https://openalex.org/I2799899409"],"apc_list":{"value":3850,"currency":"USD","value_usd":3850},"apc_paid":null,"fwci":0.3271,"has_fulltext":true,"cited_by_count":81,"citation_normalized_percentile":{"value":0.29426591,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"2","issue":"2","first_page":"82","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beta-cell-dysfunction","display_name":"beta-cell dysfunction","score":0.7540000081062317},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.6859999895095825},{"id":"https://openalex.org/keywords/impaired-glucose-tolerance","display_name":"impaired glucose tolerance","score":0.7080000042915344},{"id":"https://openalex.org/keywords/first-phase-insulin-response","display_name":"first-phase insulin response","score":0.8889999985694885},{"id":"https://openalex.org/keywords/beta-cell-mass","display_name":"beta-cell mass","score":0.8270000219345093},{"id":"https://openalex.org/keywords/glucolipotoxicity","display_name":"glucolipotoxicity","score":0.8289999961853027},{"id":"https://openalex.org/keywords/beta-cell-apoptosis","display_name":"beta-cell apoptosis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/endoplasmic-reticulum-stress","display_name":"endoplasmic reticulum stress","score":0.9789999723434448},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9990000128746033},{"id":"https://openalex.org/keywords/thioredoxin","display_name":"thioredoxin","score":0.949999988079071},{"id":"https://openalex.org/keywords/txnip","display_name":"TXNIP","score":0.9520000219345093},{"id":"https://openalex.org/keywords/genetic-risk-variants","display_name":"genetic risk variants","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7872196435928345},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.7631801962852478},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7219898104667664},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.690389096736908},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6815162897109985},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.6446487903594971},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5926614999771118},{"id":"https://openalex.org/C2780609358","wikidata":"https://www.wikidata.org/wiki/Q2087205","display_name":"Impaired glucose tolerance","level":4,"score":0.5840800404548645},{"id":"https://openalex.org/C44353895","wikidata":"https://www.wikidata.org/wiki/Q6556772","display_name":"Lipotoxicity","level":4,"score":0.5829789638519287},{"id":"https://openalex.org/C2778302649","wikidata":"https://www.wikidata.org/wiki/Q16956975","display_name":"Overnutrition","level":3,"score":0.45721957087516785},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.2900238037109375}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1111/j.2040-1124.2010.00094.x","doi":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.2040-1124.2010.00094.x","source":{"id":"https://openalex.org/S107365432","display_name":"Journal of Diabetes Investigation","issn_l":"2040-1116","issn":["2040-1116","2040-1124"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310322041","host_organization_name":"Asian Association for the Study of Diabetes","host_organization_lineage":["https://openalex.org/P4310322041"],"host_organization_lineage_names":["Asian Association for the Study of Diabetes"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Diabetes Investigation","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3001450","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4015541","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4015541","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4015541","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Diabetes Investig","raw_type":"Text"},{"id":"pmid:24843466","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24843466","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of diabetes investigation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.2040-1124.2010.00094.x","doi":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.2040-1124.2010.00094.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.2040-1124.2010.00094.x","source":{"id":"https://openalex.org/S107365432","display_name":"Journal of Diabetes Investigation","issn_l":"2040-1116","issn":["2040-1116","2040-1124"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310322041","host_organization_name":"Asian Association for the Study of Diabetes","host_organization_lineage":["https://openalex.org/P4310322041"],"host_organization_lineage_names":["Asian Association for the Study of Diabetes"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Diabetes Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1710400459.pdf","grobid_xml":"https://content.openalex.org/works/W1710400459.grobid-xml"},"referenced_works_count":88,"referenced_works":["https://openalex.org/W1582261481","https://openalex.org/W1598254642","https://openalex.org/W1963953521","https://openalex.org/W1970654240","https://openalex.org/W1971579526","https://openalex.org/W1973794425","https://openalex.org/W1978062520","https://openalex.org/W1979338372","https://openalex.org/W1981581852","https://openalex.org/W1981862063","https://openalex.org/W1983423690","https://openalex.org/W1991029690","https://openalex.org/W2003252351","https://openalex.org/W2005754586","https://openalex.org/W2006313405","https://openalex.org/W2010290591","https://openalex.org/W2018607502","https://openalex.org/W2018932672","https://openalex.org/W2019972832","https://openalex.org/W2021624889","https://openalex.org/W2024378513","https://openalex.org/W2025651276","https://openalex.org/W2028264140","https://openalex.org/W2030153054","https://openalex.org/W2036400933","https://openalex.org/W2036800308","https://openalex.org/W2036906474","https://openalex.org/W2039813542","https://openalex.org/W2040692229","https://openalex.org/W2042362312","https://openalex.org/W2047292838","https://openalex.org/W2048211245","https://openalex.org/W2050956535","https://openalex.org/W2054902503","https://openalex.org/W2057212276","https://openalex.org/W2057935783","https://openalex.org/W2059216373","https://openalex.org/W2060173445","https://openalex.org/W2061216487","https://openalex.org/W2061741332","https://openalex.org/W2066407703","https://openalex.org/W2069981583","https://openalex.org/W2082419614","https://openalex.org/W2084473188","https://openalex.org/W2089147890","https://openalex.org/W2091978165","https://openalex.org/W2094434238","https://openalex.org/W2095577197","https://openalex.org/W2100465511","https://openalex.org/W2102076191","https://openalex.org/W2103338840","https://openalex.org/W2106586196","https://openalex.org/W2109480770","https://openalex.org/W2110124224","https://openalex.org/W2111824788","https://openalex.org/W2112759538","https://openalex.org/W2113544353","https://openalex.org/W2113745162","https://openalex.org/W2117812417","https://openalex.org/W2121328463","https://openalex.org/W2122245725","https://openalex.org/W2122929112","https://openalex.org/W2127825630","https://openalex.org/W2131155467","https://openalex.org/W2131494996","https://openalex.org/W2131696835","https://openalex.org/W2135491433","https://openalex.org/W2140951430","https://openalex.org/W2143243643","https://openalex.org/W2147252435","https://openalex.org/W2150512204","https://openalex.org/W2153965694","https://openalex.org/W2154517237","https://openalex.org/W2156044622","https://openalex.org/W2160437641","https://openalex.org/W2160812382","https://openalex.org/W2163725144","https://openalex.org/W2166142060","https://openalex.org/W2170492101","https://openalex.org/W2314654899","https://openalex.org/W2316478943","https://openalex.org/W2330788525","https://openalex.org/W2334309509","https://openalex.org/W2346566459","https://openalex.org/W2412155288","https://openalex.org/W2464190089","https://openalex.org/W2766520046","https://openalex.org/W4240175730"],"related_works":["https://openalex.org/W2013604729","https://openalex.org/W1974325232","https://openalex.org/W2117693425","https://openalex.org/W1584646599","https://openalex.org/W2022016870","https://openalex.org/W2514146547","https://openalex.org/W2084815429","https://openalex.org/W2170780334","https://openalex.org/W2035226712","https://openalex.org/W4404579213"],"abstract_inverted_index":{"Type":[0],"2":[1,36,66,90,95,117,122,156,189,198,271],"diabetic":[2,176],"patients":[3],"are":[4,245,275],"insulin":[5,27,50,53,75,111,143],"resistant":[6],"as":[7],"a":[8,13,41,80,149,169,201,253],"result":[9],"of":[10,64,82,128,175,187,207,238],"obesity":[11],"and":[12,88,102,142,158,166,177,204,227,269,278],"sedentary":[14],"lifestyle.":[15],"Nevertheless,":[16],"it":[17],"has":[18],"been":[19],"known":[20],"for":[21,108],"the":[22,62,105,109,126,184,236],"past":[23],"five":[24],"decades":[25],"that":[26,43,73,113],"response":[28,54,76],"to":[29,55,77,133,220,240,266,281],"nutrients":[30],"is":[31,39,57,79,200],"markedly":[32],"diminished":[33],"in":[34,61,151,154,218,235,248,264],"type":[35,65,89,94,116,121,155,188,197,270],"diabetes.":[37,67,91,118,272],"There":[38],"now":[40],"consensus":[42],"impaired":[44,74,84],"glucose":[45,56,78,85],"regulation":[46],"cannot":[47],"develop":[48],"without":[49],"deficiency.":[51],"First-phase":[52],"lost":[58],"very":[59],"early":[60],"development":[63],"Several":[68,145],"prospective":[69],"studies":[70],"have":[71,147,162],"shown":[72,148],"predictor":[81],"future":[83,115],"tolerance":[86],"(IGT)":[87],"Recently":[92],"discovered":[93],"diabetes-risk":[96],"gene":[97],"variants":[98],"influence":[99],"\u03b2-cell":[100,152,173,185,210,267],"function,":[101],"might":[103,233,261,279],"represent":[104],"molecular":[106],"basis":[107,127],"low":[110],"secretion":[112],"predicts":[114],"We":[119],"believe":[120],"diabetes":[123,157,190,199,208],"develops":[124],"on":[125],"normal":[129],"but":[130],"'weak'\u03b2-cells":[131],"unable":[132],"cope":[134],"with":[135,212],"excessive":[136],"functional":[137,193],"demands":[138],"imposed":[139],"by":[140],"overnutrition":[141],"resistance.":[144],"laboratories":[146],"reduction":[150],"mass":[153],"IGT,":[159],"whereas":[160],"others":[161],"found":[163],"modest":[164],"reductions":[165],"most":[167],"importantly,":[168],"large":[170],"overlap":[171],"between":[172],"masses":[174],"normoglycemic":[178],"subjects.":[179],"Therefore,":[180],"at":[181],"least":[182],"initially,":[183],"dysfunction":[186],"seems":[191],"more":[192],"than":[194],"structural.":[195],"However,":[196],"progressive":[202],"disorder,":[203],"animal":[205],"models":[206],"show":[209,223],"apoptosis":[211,268],"prolonged":[213],"hyperglycemia/hyperlipemia":[214],"(glucolipotoxicity).":[215],"\u03b2-Cells":[216,244],"exposed":[217],"vitro":[219],"glucolipotoxic":[221],"conditions":[222],"endoplasmic":[224],"reticulum":[225],"(ER)":[226],"oxidative":[228],"stress.":[229],"ER":[230],"stress":[231],"mechanisms":[232],"participate":[234],"adaptation":[237],"\u03b2-cells":[239],"hyperglycemia,":[241],"unless":[242],"excessive.":[243],"not":[246],"deficient":[247],"anti-oxidant":[249],"defense,":[250],"thioredoxin":[251],"playing":[252],"major":[254],"role.":[255],"Its":[256],"inhibitor,":[257],"thioredoxin-interacting":[258],"protein":[259],"(TXNIP),":[260],"be":[262],"important":[263],"leading":[265],"These":[273],"topics":[274],"intensively":[276],"investigated":[277],"lead":[280],"novel":[282],"therapeutic":[283],"approaches.":[284],"(J":[285],"Diabetes":[286],"Invest,":[287],"doi:":[288],"10.1111/j.2040-1124.2010.00094.x,":[289],"2011).":[290]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}