{"id":"https://openalex.org/W1704867971","doi":"https://doi.org/10.3109/02770903.2015.1014099","title":"The effect of exercise on exhaled nitric oxide depends on allergic rhinoconjunctivitis in children","display_name":"The effect of exercise on exhaled nitric oxide depends on allergic rhinoconjunctivitis in children","publication_year":2015,"publication_date":"2015-05-19","ids":{"openalex":"https://openalex.org/W1704867971","doi":"https://doi.org/10.3109/02770903.2015.1014099","mag":"1704867971","pmid":"https://pubmed.ncbi.nlm.nih.gov/25985708"},"language":"en","primary_location":{"id":"doi:10.3109/02770903.2015.1014099","doi":"https://doi.org/10.3109/02770903.2015.1014099","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02770903.2015.1014099","pdf_url":null,"source":{"id":"https://openalex.org/S143944388","display_name":"Journal of Asthma","issn_l":"0277-0903","issn":["0277-0903","1532-4303"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Asthma","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063060890","display_name":"Bj\u00f8rg Evjenth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801800136","display_name":"Nordland Hospital Trust","ror":"https://ror.org/04wjd1a07","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2801800136","https://openalex.org/I63903255"]},{"id":"https://openalex.org/I4210109413","display_name":"Nordland Hospital","ror":"https://ror.org/01pj4nt72","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I4210109413"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"Bj\u00f8rg Evjenth","raw_affiliation_strings":["a Department of Pediatrics, Division of Pediatrics , Obstetrics and Women's Health, Nordland Hospital , Bod\u00f8 , Norway and","Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Department of Pediatrics, Division of Pediatrics , Obstetrics and Women's Health, Nordland Hospital , Bod\u00f8 , Norway and","institution_ids":["https://openalex.org/I2801800136","https://openalex.org/I4210109413"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and","institution_ids":["https://openalex.org/I2801800136","https://openalex.org/I4210109413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045028755","display_name":"Tonje Elisabeth Hansen","orcid":"https://orcid.org/0000-0001-9987-0433","observed_orcids":["https://orcid.org/0000-0001-9987-0433"]},"institutions":[{"id":"https://openalex.org/I2801800136","display_name":"Nordland Hospital Trust","ror":"https://ror.org/04wjd1a07","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2801800136","https://openalex.org/I63903255"]},{"id":"https://openalex.org/I4210109413","display_name":"Nordland Hospital","ror":"https://ror.org/01pj4nt72","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I4210109413"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Tonje E. Hansen","raw_affiliation_strings":["Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and","institution_ids":["https://openalex.org/I2801800136","https://openalex.org/I4210109413"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069976729","display_name":"Jan Holt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801800136","display_name":"Nordland Hospital Trust","ror":"https://ror.org/04wjd1a07","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2801800136","https://openalex.org/I63903255"]},{"id":"https://openalex.org/I4210109413","display_name":"Nordland Hospital","ror":"https://ror.org/01pj4nt72","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I4210109413"]},{"id":"https://openalex.org/I78037679","display_name":"UiT The Arctic University of Norway","ror":"https://ror.org/00wge5k78","country_code":"NO","type":"education","lineage":["https://openalex.org/I78037679"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Jan Holt","raw_affiliation_strings":["Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and ; Institute of Clinical Medicine, University of Troms\u00f8, Troms\u00f8, Norway","Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and","Institute of Clinical Medicine, University of Troms\u00f8, Troms\u00f8, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and ; Institute of Clinical Medicine, University of Troms\u00f8, Troms\u00f8, Norway","institution_ids":["https://openalex.org/I2801800136","https://openalex.org/I4210109413","https://openalex.org/I78037679"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatrics, Obstetrics and Women's Health, Nordland Hospital, Bod\u00f8, Norway and","institution_ids":["https://openalex.org/I2801800136","https://openalex.org/I4210109413"]},{"raw_affiliation_string":"Institute of Clinical Medicine, University of Troms\u00f8, Troms\u00f8, Norway","institution_ids":["https://openalex.org/I78037679"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5063060890"],"corresponding_institution_ids":["https://openalex.org/I2801800136","https://openalex.org/I4210109413"],"apc_list":null,"apc_paid":null,"fwci":0.2326,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.61103634,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"52","issue":"8","first_page":"795","last_page":"800"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exhaled-nitric-oxide","display_name":"exhaled nitric oxide","score":0.9750000238418579},{"id":"https://openalex.org/keywords/allergic-rhinoconjunctivitis","display_name":"allergic rhinoconjunctivitis","score":0.921999990940094},{"id":"https://openalex.org/keywords/treadmill-exercise-testing","display_name":"treadmill exercise testing","score":0.6759999990463257},{"id":"https://openalex.org/keywords/childhood-asthma","display_name":"childhood asthma","score":0.9240000247955322},{"id":"https://openalex.org/keywords/allergic-phenotype","display_name":"allergic phenotype","score":0.8700000047683716},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.5730000138282776},{"id":"https://openalex.org/keywords/specific-ige","display_name":"specific IgE","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C2781142857","wikidata":"https://www.wikidata.org/wiki/Q5420174","display_name":"Exhaled nitric oxide","level":4,"score":0.9688515663146973},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9441497325897217},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.8316153883934021},{"id":"https://openalex.org/C2780333948","wikidata":"https://www.wikidata.org/wiki/Q653305","display_name":"Spirometry","level":3,"score":0.8241797685623169},{"id":"https://openalex.org/C2778531465","wikidata":"https://www.wikidata.org/wiki/Q5420019","display_name":"Exercise-induced asthma","level":3,"score":0.5599753856658936},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.494221955537796},{"id":"https://openalex.org/C2781464450","wikidata":"https://www.wikidata.org/wiki/Q839144","display_name":"Treadmill","level":2,"score":0.46334534883499146},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.45806625485420227},{"id":"https://openalex.org/C2780769369","wikidata":"https://www.wikidata.org/wiki/Q4375","display_name":"Bronchoconstriction","level":3,"score":0.4178975224494934}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003233","descriptor_name":"Conjunctivitis, Allergic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003233","descriptor_name":"Conjunctivitis, Allergic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003233","descriptor_name":"Conjunctivitis, Allergic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003233","descriptor_name":"Conjunctivitis, Allergic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005541","descriptor_name":"Forced Expiratory Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012882","descriptor_name":"Skin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013147","descriptor_name":"Spirometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/02770903.2015.1014099","doi":"https://doi.org/10.3109/02770903.2015.1014099","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02770903.2015.1014099","pdf_url":null,"source":{"id":"https://openalex.org/S143944388","display_name":"Journal of Asthma","issn_l":"0277-0903","issn":["0277-0903","1532-4303"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Asthma","raw_type":"journal-article"},{"id":"pmid:25985708","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25985708","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of asthma : official journal of the Association for the Care of Asthma","raw_type":"Controlled Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310645","display_name":"European Respiratory Society","ror":"https://ror.org/00c8n3h65"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W158079520","https://openalex.org/W1899229346","https://openalex.org/W1963426363","https://openalex.org/W1967460874","https://openalex.org/W1973047534","https://openalex.org/W1977754337","https://openalex.org/W1991452514","https://openalex.org/W1999039702","https://openalex.org/W2001486544","https://openalex.org/W2005613109","https://openalex.org/W2006830317","https://openalex.org/W2015800485","https://openalex.org/W2022358055","https://openalex.org/W2034281089","https://openalex.org/W2049036513","https://openalex.org/W2049449064","https://openalex.org/W2050216717","https://openalex.org/W2051458615","https://openalex.org/W2054510493","https://openalex.org/W2057304127","https://openalex.org/W2061042761","https://openalex.org/W2074479766","https://openalex.org/W2078348184","https://openalex.org/W2080741303","https://openalex.org/W2090674550","https://openalex.org/W2091185126","https://openalex.org/W2096847968","https://openalex.org/W2099449365","https://openalex.org/W2106107171","https://openalex.org/W2115561143","https://openalex.org/W2125078269","https://openalex.org/W2126478493","https://openalex.org/W2142081148","https://openalex.org/W2153421219","https://openalex.org/W2154914637","https://openalex.org/W2157430977","https://openalex.org/W2158057203","https://openalex.org/W2159168168","https://openalex.org/W2166347574","https://openalex.org/W2336431486","https://openalex.org/W2708295276","https://openalex.org/W4211006694","https://openalex.org/W4231724153"],"related_works":["https://openalex.org/W1963426363","https://openalex.org/W619819039","https://openalex.org/W2050216717","https://openalex.org/W2090674550","https://openalex.org/W2767975745","https://openalex.org/W2011875106","https://openalex.org/W2005613109","https://openalex.org/W1976355099","https://openalex.org/W2905942072","https://openalex.org/W1987660614"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Fractional":[1],"exhaled":[2],"nitric":[3],"oxide":[4],"(FENO)":[5],"and":[6,42,78,94,118,132,208,240],"exercise":[7,26,41,67,99,222],"testing":[8],"are":[9],"widely":[10],"used":[11],"for":[12],"the":[13,22,38,54,103,187,200,228],"evaluation":[14],"of":[15,24,56,72,155,173,181,221,232],"pediatric":[16],"asthma.":[17],"The":[18,143,219],"evidence":[19],"relating":[20],"to":[21,46,52,63,244],"effects":[23,55],"strenuous":[25],"on":[27,37,58,149,223,227],"FENO":[28,43,60,87,126,144,164,203,224,235],"in":[29,44,61,129,202],"children":[30,74,81,161,194],"is":[31,35],"conflicting.":[32],"Little":[33],"information":[34],"available":[36],"association":[39],"between":[40],"relation":[45],"allergic":[47,229],"rhinoconjunctivitis":[48],"(AR).":[49],"We":[50],"aimed":[51],"investigate":[53],"AR":[57,135,138,150],"children's":[59],"response":[62],"a":[64,171,177],"standardized":[65],"treadmill":[66],"test.":[68],"METHODS:":[69],"A":[70,110],"total":[71],"124":[73,79],"with":[75,107,134,162,176],"current":[76],"asthma":[77,156,233],"non-asthmatic":[80],"aged":[82],"8-16":[83],"years":[84],"were":[85,122],"studied.":[86],"was":[88,127,147,189,204,214,225],"measured":[89],"at":[90,92,167,184,197],"baseline,":[91],"1":[93,168,198],"30":[95,185,210,248],"min":[96,169,199,211],"after":[97,238],"an":[98],"challenge":[100],"test":[101],"using":[102],"single":[104],"breath":[105],"technique":[106],"EcoMedics":[108],"Exhalyzer.":[109],"structured":[111],"parental":[112],"interview,":[113],"spirometry,":[114],"serum":[115],"allergen-specific":[116],"IgE":[117],"skin":[119],"prick":[120],"tests":[121],"performed.":[123],"RESULTS:":[124],"Baseline":[125],"higher":[128],"both":[130],"asthmatics":[131],"non-asthmatics":[133],"than":[136],"without":[137,195],"(both":[139],"p":[140],"<":[141],"0.001).":[142],"time":[145],"trend":[146],"dependent":[148,226],"(p":[151,157],"=":[152,158],"0.039),":[153],"irrespective":[154],"0.876).":[159],"In":[160,193],"AR,":[163,196],"had":[165],"declined":[166],"by":[170,209],"mean":[172],"6.1":[174],"ppb":[175,207],"95%":[178],"confidence":[179],"level":[180,246],"5.1-7.5":[182],"ppb;":[183],"min,":[186],"reduction":[188],"2.8":[190],"(2.5-3.3)":[191],"ppb.":[192,217],"decline":[201],"2.7":[205],"(2.1-3.5)":[206],"post-exercise":[212],"it":[213],"1.6":[215],"(1.3-2.0)":[216],"CONCLUSIONS:":[218],"impact":[220],"phenotype,":[230],"regardless":[231],"status.":[234],"decreased":[236],"immediately":[237],"exercise,":[239],"did":[241],"not":[242],"return":[243],"baseline":[245],"within":[247],"min.":[249]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}