{"id":"https://openalex.org/W1703822356","doi":null,"title":"Plasmid-mediated AmpC beta-lactamase-producing Escherichia coli causing urinary tract infection in the Auckland community likely to be resistant to commonly prescribed antimicrobials.","display_name":"Plasmid-mediated AmpC beta-lactamase-producing Escherichia coli causing urinary tract infection in the Auckland community likely to be resistant to commonly prescribed antimicrobials.","publication_year":2015,"publication_date":"2015-03-13","ids":{"openalex":"https://openalex.org/W1703822356","mag":"1703822356","pmid":"https://pubmed.ncbi.nlm.nih.gov/25829039"},"language":"en","primary_location":{"id":"pmid:25829039","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25829039","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New Zealand medical journal","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047674333","display_name":"Dragana Drinkovi\u0107","orcid":"https://orcid.org/0000-0002-9546-5737","observed_orcids":["https://orcid.org/0000-0002-9546-5737"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dragana Drinkovic","raw_affiliation_strings":["Microbiology Laboratory, Labtests, PO Box 12049, Penrose, Auckland 1642, New Zealand. dragana.drinkovic@labtests.co.nz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology Laboratory, Labtests, PO Box 12049, Penrose, Auckland 1642, New Zealand. dragana.drinkovic@labtests.co.nz","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062571935","display_name":"Arthur J. Morris","orcid":"https://orcid.org/0000-0002-0860-7187","observed_orcids":["https://orcid.org/0000-0002-0860-7187"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arthur J Morris","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004046142","display_name":"Kristin H. Dyet","orcid":"https://orcid.org/0000-0003-2508-6843","observed_orcids":["https://orcid.org/0000-0003-2508-6843"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristin Dyet","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038157206","display_name":"Sarah Bakker","orcid":"https://orcid.org/0000-0003-2700-2316","observed_orcids":["https://orcid.org/0000-0003-2700-2316"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah Bakker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5082217676","display_name":"Helen Heffernan","orcid":"https://orcid.org/0000-0003-1801-5174","observed_orcids":["https://orcid.org/0000-0003-1801-5174"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Helen Heffernan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1059,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.74241995,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"128","issue":"1410","first_page":"50","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11232","display_name":"Urinary Tract Infections Management","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmid-mediated-ampc-beta-lactamase","display_name":"plasmid-mediated AmpC beta-lactamase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9819999933242798},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.9950000047683716},{"id":"https://openalex.org/keywords/community-acquired-infections","display_name":"community-acquired infections","score":0.875},{"id":"https://openalex.org/keywords/cmy-2","display_name":"CMY-2","score":0.8069999814033508},{"id":"https://openalex.org/keywords/extended-spectrum-beta-lactamase","display_name":"extended-spectrum beta-lactamase","score":0.9169999957084656},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.8059999942779541},{"id":"https://openalex.org/keywords/norfloxacin-resistance","display_name":"norfloxacin resistance","score":0.8309999704360962},{"id":"https://openalex.org/keywords/trimethoprim-resistance","display_name":"trimethoprim resistance","score":0.9340000152587891},{"id":"https://openalex.org/keywords/nitrofurantoin-resistance","display_name":"nitrofurantoin resistance","score":0.9940000176429749},{"id":"https://openalex.org/keywords/st131","display_name":"ST131","score":0.8519999980926514}],"concepts":[{"id":"https://openalex.org/C2776124114","wikidata":"https://www.wikidata.org/wiki/Q2353907","display_name":"Cefoxitin","level":4,"score":0.7960530519485474},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.7669082880020142},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7292791604995728},{"id":"https://openalex.org/C42084846","wikidata":"https://www.wikidata.org/wiki/Q855275","display_name":"Pulsed-field gel electrophoresis","level":4,"score":0.7006770372390747},{"id":"https://openalex.org/C2781288988","wikidata":"https://www.wikidata.org/wiki/Q311379","display_name":"Beta-lactamase","level":4,"score":0.5506368279457092},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5325609445571899},{"id":"https://openalex.org/C2777629877","wikidata":"https://www.wikidata.org/wiki/Q422669","display_name":"Nitrofurantoin","level":4,"score":0.5219361782073975},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.4754825830459595},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.459331214427948},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.45886868238449097},{"id":"https://openalex.org/C2778746504","wikidata":"https://www.wikidata.org/wiki/Q417897","display_name":"Norfloxacin","level":4,"score":0.42633628845214844},{"id":"https://openalex.org/C2778897966","wikidata":"https://www.wikidata.org/wiki/Q183554","display_name":"Fosfomycin","level":3,"score":0.4150215685367584},{"id":"https://openalex.org/C2778512257","wikidata":"https://www.wikidata.org/wiki/Q256602","display_name":"Ciprofloxacin","level":3,"score":0.41319364309310913},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.33237916231155396},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3074469566345215},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2285117208957672},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16357210278511047},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.15924355387687683},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08763083815574646},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.061900317668914795}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004927","descriptor_name":"Escherichia coli Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D004927","descriptor_name":"Escherichia coli Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D004927","descriptor_name":"Escherichia coli Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009520","descriptor_name":"New Zealand","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014552","descriptor_name":"Urinary Tract Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014552","descriptor_name":"Urinary Tract Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D014552","descriptor_name":"Urinary Tract Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D017714","descriptor_name":"Community-Acquired Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D017714","descriptor_name":"Community-Acquired Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D017714","descriptor_name":"Community-Acquired Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D017720","descriptor_name":"Molecular Epidemiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024881","descriptor_name":"Drug Resistance, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:25829039","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25829039","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New Zealand medical journal","raw_type":"Journal Article"},{"id":"mag:1703822356","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25829039","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7097421921","https://openalex.org/W2209989432","https://openalex.org/W2410176594","https://openalex.org/W4200552201","https://openalex.org/W2412741445","https://openalex.org/W4383620704","https://openalex.org/W2320266514","https://openalex.org/W2336226729","https://openalex.org/W2056036109","https://openalex.org/W2197753709"],"abstract_inverted_index":{"AIM:":[0],"To":[1],"estimate":[2],"the":[3,15,27,51,63,106,179,211,228,243,296,311,323,326,331,377,387,416],"prevalence":[4,137,302],"and":[5,35,56,77,86,96,108,116,154,204,220,239,389],"characterise":[6],"plasmid-mediated":[7],"AmpC":[8,54,133],"beta-lactamase":[9],"(PMACBL)-":[10],"producing":[11],"Escherichia":[12],"coli":[13,24,124,141,146,158,172,189,215,259,286,306,329,380],"in":[14,227,295,310,317,330,386,415],"Auckland":[16,29,312,332],"community.":[17],"METHOD:":[18],"All":[19],"cefoxitin":[20],"non-susceptible":[21],"(NS)":[22],"E.":[23,123,140,145,157,171,188,214,258,274,285,305,328,368,379],"identified":[25],"at":[26],"two":[28],"community":[30,353,388],"laboratories":[31],"between":[32],"1":[33],"January":[34],"31":[36],"August":[37],"2011":[38],"were":[39,70,102,125,147,191,207,216,221,245,287,334,358,390],"referred":[40],"to":[41,49,61,81,87,105,151,200,283,345,361,383],"ESR":[42],"for":[43],"boronic":[44],"acid":[45],"double-disc":[46],"synergy":[47],"testing,":[48],"detect":[50],"production":[52],"of":[53,65,98,119,131,138,178,210,230,242,250,303,325,351,376,401],"beta-lactamase,":[55,134],"polymerase":[57],"chain":[58],"reaction":[59],"(PCR)":[60],"identify":[62,88],"presence":[64],"PMACBL":[66,126,163],"genes.":[67],"PMACBL-producing":[68,139,144,170,180,187,213,257,284,304,327,378],"isolates":[69,181,190,357,381],"typed":[71],"using":[72],"pulsed-field":[73],"gel":[74],"electrophoresis":[75],"(PFGE),":[76],"PCR":[78],"was":[79,142,236,307],"used":[80],"determine":[82],"their":[83,195],"phylogenetic":[84,201],"group":[85,202],"multilocus":[89],"sequence":[90],"type":[91],"(ST)131.":[92],"Antimicrobial":[93],"susceptibility":[94],"testing":[95],"detection":[97],"extended-spectrum":[99],"beta-lactamases":[100],"(ESBLs)":[101],"performed":[103],"according":[104],"Clinical":[107],"Laboratory":[109],"Standards":[110],"Institute":[111],"recommendations.":[112],"RESULTS:":[113],"101":[114,212],"(51%)":[115],"74":[117],"(37%)":[118],"200":[120],"non-duplicate":[121],"cefoxitin-NS":[122],"producers":[127],"or":[128,342],"assumed":[129],"hyper-producers":[130],"chromosomal":[132],"respectively.":[135],"The":[136,186,232,301,356,374],"0.4%.":[143],"significantly":[148],"less":[149],"susceptible":[150],"norfloxacin,":[152],"trimethoprim":[153],"nitrofurantoin":[155],"than":[156,264,364],"that":[159,322,338],"produced":[160],"neither":[161,288],"a":[162,183,261,339],"nor":[164,290,410],"an":[165,174],"ESBL.":[166,175],"Very":[167],"few":[168,371],"(4%)":[169],"co-produced":[173],"Most":[176],"(88%)":[177],"had":[182,291,406,411],"CMY-2-like":[184],"PMACBL.":[185],"diverse":[192],"based":[193],"on":[194],"PFGE":[196],"profiles,":[197],"44%":[198],"belonged":[199],"D,":[203],"only":[205],"four":[206],"ST131.":[208],"100":[209],"cultured":[217],"from":[218,394],"urine,":[219],"causing":[222],"urinary":[223],"tract":[224],"infection":[225],"(UTI)":[226],"majority":[229,324,375],"patients.":[231],"median":[233],"patient":[234],"age":[235],"56":[237],"years":[238],"most":[240,391],"(94%)":[241],"patients":[244,251,265,278,402],"women.":[246],"A":[247,398],"greater":[248],"proportion":[249,400],"with":[252,266,279,396,403],"community-acquired":[253,267,280,404],"UTI":[254,268,281,405],"caused":[255,269],"by":[256,270],"received":[260],"beta-lactam":[262],"antimicrobial":[263,293,413],"other":[271,365],"non-AmpC,":[272,366],"non-ESBL-producing":[273,367],"coli.":[275],"Thirty-six":[276],"(43%)":[277],"due":[282],"hospitalised":[289,409],"any":[292,412],"treatment":[294,372,414],"previous":[297,417],"6":[298,418],"months.":[299,419],"CONCLUSION:":[300],"relatively":[308],"low":[309],"community,":[313],"but":[314],"has":[315],"increased":[316],"recent":[318],"years.":[319],"Typing":[320],"revealed":[321],"region":[333],"genetically":[335],"unrelated":[336],"meaning":[337],"point":[340],"source":[341],"direct":[343],"person":[344,346],"transmission":[347],"are":[348],"not":[349,407],"drivers":[350],"local":[352],"spread":[354],"currently.":[355],"more":[359],"resistant":[360],"non-beta-lactam":[362],"antimicrobials":[363],"coli,":[369],"leaving":[370],"options.":[373],"seemed":[382],"be":[384],"acquired":[385],"frequently":[392],"isolated":[393],"women":[395],"UTI.":[397],"large":[399],"been":[408]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}