{"id":"https://openalex.org/W170209744","doi":null,"title":"Factors related to maternal transmission of mutans streptococci in high-risk children-pilot study.","display_name":"Factors related to maternal transmission of mutans streptococci in high-risk children-pilot study.","publication_year":2012,"publication_date":"2012-07-01","ids":{"openalex":"https://openalex.org/W170209744","mag":"170209744","pmid":"https://pubmed.ncbi.nlm.nih.gov/23014079"},"language":"en","primary_location":{"id":"pmid:23014079","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23014079","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric dentistry","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103126658","display_name":"Ling Zhan","orcid":"https://orcid.org/0000-0002-2186-8410","observed_orcids":["https://orcid.org/0000-0002-2186-8410"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ling Zhan","raw_affiliation_strings":["Department of Preventive and Restorative Dental Sciences, the University of California, San Francisco, Calif, USA. zhanl@dentistry.ucsf.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive and Restorative Dental Sciences, the University of California, San Francisco, Calif, USA. zhanl@dentistry.ucsf.edu","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045094924","display_name":"Stella Tan","orcid":"https://orcid.org/0000-0001-5846-1916","observed_orcids":["https://orcid.org/0000-0001-5846-1916"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stella Tan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072929035","display_name":"Pamela K. Den Besten","orcid":"https://orcid.org/0000-0002-2107-6229","observed_orcids":["https://orcid.org/0000-0002-2107-6229"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pamela Den Besten","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028748317","display_name":"J.D.B. Featherstone","orcid":"https://orcid.org/0000-0001-5185-5816","observed_orcids":["https://orcid.org/0000-0001-5185-5816"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John D B Featherstone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5088780849","display_name":"Charles I. Hoover","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles I Hoover","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.9266,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.90068994,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"34","issue":"4","first_page":"e86","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10113","display_name":"Dental materials and restorations","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mutans-streptococci","display_name":"mutans streptococci","score":0.9829999804496765},{"id":"https://openalex.org/keywords/mother-to-child-transmission","display_name":"mother-to-child transmission","score":0.9039999842643738},{"id":"https://openalex.org/keywords/streptococcus-mutans","display_name":"Streptococcus mutans","score":0.9079999923706055},{"id":"https://openalex.org/keywords/streptococcus-sobrinus","display_name":"Streptococcus sobrinus","score":0.996999979019165},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.843999981880188},{"id":"https://openalex.org/keywords/mutacin","display_name":"mutacin","score":0.8180000185966492},{"id":"https://openalex.org/keywords/biofilm-formation","display_name":"biofilm formation","score":0.9950000047683716},{"id":"https://openalex.org/keywords/dental-caries","display_name":"dental caries","score":0.8320000171661377},{"id":"https://openalex.org/keywords/at-risk-children","display_name":"vulnerable children","score":0.7139999866485596},{"id":"https://openalex.org/keywords/oral-colonization","display_name":"oral colonization","score":0.367000013589859}],"concepts":[{"id":"https://openalex.org/C2779958046","wikidata":"https://www.wikidata.org/wiki/Q603315","display_name":"Streptococcus sobrinus","level":4,"score":0.9649583101272583},{"id":"https://openalex.org/C2778430296","wikidata":"https://www.wikidata.org/wiki/Q131452","display_name":"Streptococcus mutans","level":3,"score":0.8686926364898682},{"id":"https://openalex.org/C2780368718","wikidata":"https://www.wikidata.org/wiki/Q7623352","display_name":"Streptococcus gordonii","level":4,"score":0.7615994215011597},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.7371319532394409},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6223335862159729},{"id":"https://openalex.org/C2778276568","wikidata":"https://www.wikidata.org/wiki/Q190161","display_name":"Streptococcus","level":3,"score":0.5973890423774719},{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.5952520370483398},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5921583771705627},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.5473702549934387},{"id":"https://openalex.org/C2777867728","wikidata":"https://www.wikidata.org/wiki/Q2033849","display_name":"Streptococcus sanguinis","level":4,"score":0.5450485348701477},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.5014195442199707},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3554421067237854},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.20679563283920288},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14638110995292664},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07006233930587769},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.062691330909729},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D013295","descriptor_name":"Streptococcus mutans","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018445","descriptor_name":"Infectious Disease Transmission, Vertical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:23014079","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23014079","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric dentistry","raw_type":"Journal Article"},{"id":"mag:170209744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23014079","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W169238571","https://openalex.org/W2560757149","https://openalex.org/W2518991464","https://openalex.org/W2010519244","https://openalex.org/W2464616924","https://openalex.org/W2408898219","https://openalex.org/W2145673400","https://openalex.org/W7024903705","https://openalex.org/W2215612474","https://openalex.org/W2068798598"],"abstract_inverted_index":{"PURPOSE:":[0],"The":[1],"purpose":[2],"of":[3,15,45,60,89],"this":[4],"study":[5,148],"was":[6,47,107,120],"to":[7,33],"investigate":[8],"virulence":[9],"factors":[10],"associated":[11],"with":[12,27],"maternal":[13,92,158],"transmission":[14,106],"mutans":[16,71,96,159],"streptococci":[17,160],"(MS).":[18],"METHODS:":[19],"Saliva":[20],"samples":[21],"were":[22,39,77,103],"collected":[23],"from":[24,41],"10":[25],"mothers":[26,81],"active":[28],"caries":[29],"and":[30,57,73,82,98,128],"their":[31],"2-":[32],"5-year-old":[34],"children.":[35],"Ten":[36],"MS":[37,46,85],"colonies":[38],"isolated":[40],"each":[42],"subject.":[43],"Transmission":[44],"identified":[48],"by":[49],"arbitrarily":[50],"primed":[51],"polymerase":[52],"chain":[53],"reactions.":[54],"Biofilm":[55],"formation":[56,125],"mutacin":[58,137],"production":[59],"the":[61,90],"isolates":[62],"against":[63,138],"Streptococcus":[64,67,70,74,95,100,139],"gordonii":[65],"10558,":[66],"sanguinis":[68],"10557,":[69],"25175,":[72],"sobrinus":[75,101,140],"6715":[76,141],"analyzed.":[78],"RESULTS:":[79],"All":[80],"children":[83,115],"had":[84,116],"colonization.":[86],"Only":[87],"7":[88],"36":[91],"genotypes":[93,97,130],"(33":[94],"3":[99],"genotypes)":[102],"transmitted.":[104],"Maternal":[105],"found":[108],"in":[109,123],"4":[110],"mother-child":[111],"pairs,":[112],"whereas":[113],"9":[114],"nonmaternal":[117,154],"genotypes.":[118,144],"There":[119],"no":[121],"difference":[122],"biofilm":[124],"between":[126],"transmitted":[127],"nontransmitted":[129,143],"(P>.05).":[131],"Transmitted":[132],"genotypes,":[133],"however,":[134],"produced":[135],"more":[136],"than":[142],"CONCLUSIONS:":[145],"This":[146],"pilot":[147],"showed":[149],"that":[150],"there":[151],"may":[152],"be":[153],"as":[155,157],"well":[156],"transmission.":[161]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}