{"id":"https://openalex.org/W17018127","doi":null,"title":"The effects of rheum officinale on the progression of feline chronic kidney disease.","display_name":"The effects of rheum officinale on the progression of feline chronic kidney disease.","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W17018127","mag":"17018127"},"language":"en","primary_location":{"id":"pmh:oai:krex.k-state.edu:2097/9265","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2097/9265","pdf_url":"http://hdl.handle.net/2097/9265","source":{"id":"https://openalex.org/S4306402339","display_name":"K-State Research Exchange (Kansas State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I189590672","host_organization_name":"Kansas State University","host_organization_lineage":["https://openalex.org/I189590672"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2097/9265","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040024097","display_name":"Andrew S. Hanzlicek","orcid":"https://orcid.org/0000-0001-6523-4033","observed_orcids":["https://orcid.org/0000-0001-6523-4033"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hanzlicek, Andrew S.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5040024097"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.053599998354911804,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheum-officinale","display_name":"Rheum officinale","score":0.9509999752044678},{"id":"https://openalex.org/keywords/chinese-rhubarb","display_name":"Chinese rhubarb","score":0.8370000123977661},{"id":"https://openalex.org/keywords/feline-chronic-kidney-disease","display_name":"feline chronic kidney disease","score":0.9900000095367432},{"id":"https://openalex.org/keywords/cats","display_name":"cats","score":0.5529999732971191},{"id":"https://openalex.org/keywords/benazepril","display_name":"benazepril","score":0.7570000290870667},{"id":"https://openalex.org/keywords/herbal-supplementation","display_name":"herbal supplementation","score":0.597000002861023},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.8289999961853027},{"id":"https://openalex.org/keywords/iris-staging","display_name":"IRIS staging","score":0.7689999938011169},{"id":"https://openalex.org/keywords/phosphate-binders","display_name":"phosphate binders","score":0.578000009059906},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.8489999771118164}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8079268336296082},{"id":"https://openalex.org/C2779904517","wikidata":"https://www.wikidata.org/wiki/Q5008900","display_name":"CATS","level":2,"score":0.763220489025116},{"id":"https://openalex.org/C2780959883","wikidata":"https://www.wikidata.org/wiki/Q111146","display_name":"Hematocrit","level":2,"score":0.6811980605125427},{"id":"https://openalex.org/C99476002","wikidata":"https://www.wikidata.org/wiki/Q42297","display_name":"Analysis of variance","level":2,"score":0.6287502646446228},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.6204992532730103},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.6039667129516602},{"id":"https://openalex.org/C102959455","wikidata":"https://www.wikidata.org/wiki/Q7313954","display_name":"Repeated measures design","level":2,"score":0.586723804473877},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.576933741569519},{"id":"https://openalex.org/C2779115891","wikidata":"https://www.wikidata.org/wiki/Q7217716","display_name":"Rheum (plant)","level":3,"score":0.5131796002388},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.4902101159095764},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4581955075263977},{"id":"https://openalex.org/C152587130","wikidata":"https://www.wikidata.org/wiki/Q7092351","display_name":"One-way analysis of variance","level":3,"score":0.43099308013916016},{"id":"https://openalex.org/C2777363265","wikidata":"https://www.wikidata.org/wiki/Q592802","display_name":"Benazepril","level":3,"score":0.41319596767425537},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3335146903991699},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11584138870239258},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:krex.k-state.edu:2097/9265","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2097/9265","pdf_url":"http://hdl.handle.net/2097/9265","source":{"id":"https://openalex.org/S4306402339","display_name":"K-State Research Exchange (Kansas State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I189590672","host_organization_name":"Kansas State University","host_organization_lineage":["https://openalex.org/I189590672"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"}],"best_oa_location":{"id":"pmh:oai:krex.k-state.edu:2097/9265","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2097/9265","pdf_url":"http://hdl.handle.net/2097/9265","source":{"id":"https://openalex.org/S4306402339","display_name":"K-State Research Exchange (Kansas State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I189590672","host_organization_name":"Kansas State University","host_organization_lineage":["https://openalex.org/I189590672"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W17018127.pdf","grobid_xml":"https://content.openalex.org/works/W17018127.grobid-xml"},"referenced_works_count":175,"referenced_works":["https://openalex.org/W44797566","https://openalex.org/W52172449","https://openalex.org/W75189296","https://openalex.org/W82209922","https://openalex.org/W136365167","https://openalex.org/W174053276","https://openalex.org/W927144754","https://openalex.org/W1019810306","https://openalex.org/W1034142528","https://openalex.org/W1505978562","https://openalex.org/W1510586846","https://openalex.org/W1528847764","https://openalex.org/W1557028690","https://openalex.org/W1575754639","https://openalex.org/W1663371441","https://openalex.org/W1726284834","https://openalex.org/W1840163537","https://openalex.org/W1931073059","https://openalex.org/W1964081206","https://openalex.org/W1970666454","https://openalex.org/W1974150901","https://openalex.org/W1974955986","https://openalex.org/W1976433874","https://openalex.org/W1977314871","https://openalex.org/W1982313308","https://openalex.org/W1984883529","https://openalex.org/W1985209563","https://openalex.org/W1985598970","https://openalex.org/W1987032890","https://openalex.org/W1987648121","https://openalex.org/W1987749890","https://openalex.org/W1988619293","https://openalex.org/W1989145212","https://openalex.org/W1993212911","https://openalex.org/W1993404941","https://openalex.org/W1993851092","https://openalex.org/W1994519747","https://openalex.org/W1996111956","https://openalex.org/W1996498079","https://openalex.org/W1996626498","https://openalex.org/W1997310530","https://openalex.org/W1998975199","https://openalex.org/W1999112251","https://openalex.org/W2000158535","https://openalex.org/W2001832399","https://openalex.org/W2002221255","https://openalex.org/W2002621910","https://openalex.org/W2003574534","https://openalex.org/W2008098266","https://openalex.org/W2011082347","https://openalex.org/W2012034969","https://openalex.org/W2012230387","https://openalex.org/W2018730789","https://openalex.org/W2019671943","https://openalex.org/W2020420400","https://openalex.org/W2020774229","https://openalex.org/W2021915768","https://openalex.org/W2023705463","https://openalex.org/W2024784351","https://openalex.org/W2025620210","https://openalex.org/W2026942191","https://openalex.org/W2027127101","https://openalex.org/W2028148689","https://openalex.org/W2028626467","https://openalex.org/W2030122869","https://openalex.org/W2030232022","https://openalex.org/W2031782395","https://openalex.org/W2035838858","https://openalex.org/W2035876629","https://openalex.org/W2036883632","https://openalex.org/W2037364250","https://openalex.org/W2038887176","https://openalex.org/W2039188280","https://openalex.org/W2039240345","https://openalex.org/W2047122808","https://openalex.org/W2047971738","https://openalex.org/W2049177531","https://openalex.org/W2049221654","https://openalex.org/W2049665187","https://openalex.org/W2049727846","https://openalex.org/W2053324709","https://openalex.org/W2055549101","https://openalex.org/W2056604730","https://openalex.org/W2056674311","https://openalex.org/W2056937676","https://openalex.org/W2058278041","https://openalex.org/W2061106436","https://openalex.org/W2063039639","https://openalex.org/W2064098458","https://openalex.org/W2066432245","https://openalex.org/W2066534725","https://openalex.org/W2067267719","https://openalex.org/W2068642987","https://openalex.org/W2075391935","https://openalex.org/W2077203655","https://openalex.org/W2080420326","https://openalex.org/W2087027548","https://openalex.org/W2087920840","https://openalex.org/W2089698754","https://openalex.org/W2092594344","https://openalex.org/W2093073712","https://openalex.org/W2096656282","https://openalex.org/W2097273361","https://openalex.org/W2097372783","https://openalex.org/W2097805169","https://openalex.org/W2097839537","https://openalex.org/W2099963624","https://openalex.org/W2102989684","https://openalex.org/W2103016161","https://openalex.org/W2104368559","https://openalex.org/W2105130711","https://openalex.org/W2106887481","https://openalex.org/W2110358511","https://openalex.org/W2111703816","https://openalex.org/W2113456660","https://openalex.org/W2120672055","https://openalex.org/W2121126525","https://openalex.org/W2122317595","https://openalex.org/W2128757614","https://openalex.org/W2129420497","https://openalex.org/W2133596737","https://openalex.org/W2134278245","https://openalex.org/W2134382817","https://openalex.org/W2138256890","https://openalex.org/W2141564680","https://openalex.org/W2142337017","https://openalex.org/W2144507234","https://openalex.org/W2145529099","https://openalex.org/W2145902340","https://openalex.org/W2146239575","https://openalex.org/W2146843132","https://openalex.org/W2147191066","https://openalex.org/W2148977472","https://openalex.org/W2150402666","https://openalex.org/W2150767283","https://openalex.org/W2151788147","https://openalex.org/W2151861762","https://openalex.org/W2153182146","https://openalex.org/W2154186340","https://openalex.org/W2155383324","https://openalex.org/W2156726620","https://openalex.org/W2159099277","https://openalex.org/W2159628746","https://openalex.org/W2160109224","https://openalex.org/W2163070765","https://openalex.org/W2163689306","https://openalex.org/W2166994979","https://openalex.org/W2167064714","https://openalex.org/W2168020089","https://openalex.org/W2168234252","https://openalex.org/W2169560003","https://openalex.org/W2170362706","https://openalex.org/W2171208655","https://openalex.org/W2171369528","https://openalex.org/W2172114097","https://openalex.org/W2212281566","https://openalex.org/W2241455767","https://openalex.org/W2258267067","https://openalex.org/W2297148142","https://openalex.org/W2334462737","https://openalex.org/W2335187016","https://openalex.org/W2401885221","https://openalex.org/W2408961004","https://openalex.org/W2411534810","https://openalex.org/W2413944397","https://openalex.org/W2416994746","https://openalex.org/W2462662030","https://openalex.org/W2464558634","https://openalex.org/W2470574357","https://openalex.org/W3156148333","https://openalex.org/W4248084394","https://openalex.org/W4251328941","https://openalex.org/W4251919176","https://openalex.org/W4300987630","https://openalex.org/W4322702037"],"related_works":["https://openalex.org/W7097212178","https://openalex.org/W25173026","https://openalex.org/W3097836955","https://openalex.org/W7052536834","https://openalex.org/W2080536845","https://openalex.org/W3214963447","https://openalex.org/W4400063137","https://openalex.org/W2604738889","https://openalex.org/W1545945937","https://openalex.org/W2304169433"],"abstract_inverted_index":{"Chronic":[0],"kidney":[1],"disease":[2],"(CKD)":[3],"is":[4],"a":[5,81,99],"common":[6],"cause":[7],"of":[8,15,23,32],"morbidity":[9],"and":[10,43,59,104,113,125],"mortality":[11],"in":[12,49],"cats.The":[13],"purpose":[14],"this":[16],"study":[17],"was":[18],"to":[19],"investigate":[20],"the":[21,30,50],"effects":[22],"Chinese":[24,61],"rhubarb":[25,62],"(Rheum":[26],"officinale)":[27],"supplementation":[28],"on":[29],"progression":[31],"feline":[33],"CKD.Cats":[34],"with":[35],"stable":[36],"IRIS":[37],"stage":[38],"II":[39],"or":[40,93],"III":[41],"CKD":[42],"without":[44],"certain":[45],"comorbidities":[46],"were":[47,52,97,116,130],"included":[48],"study.Cats":[51],"randomly":[53],"divided":[54],"into":[55],"3":[56,119],"treatment":[57],"groups":[58,122,127],"administered":[60],"extract":[63],"(Group":[64,84,95],"1,":[65],"Rubenal\u00ae,":[66],"Vetoquinol,":[67],"Forth":[68],"Worth,":[69],"TX;":[70],"75":[71],"mg":[72],"tablet":[73],"by":[74,88],"mouth":[75,89],"every":[76,90,118],"12":[77],"h),":[78,92],"benazepril":[79],"as":[80,108],"positive":[82],"control":[83],"2,":[85],"0.5":[86],"mg/kg":[87],"24":[91],"both":[94],"3).Cats":[96],"fed":[98],"commercial":[100],"renal":[101],"specific":[102],"diet":[103],"enteric":[105],"phosphate":[106],"binder":[107],"appropriate.Body":[109],"weight,":[110],"laboratory":[111],"data,":[112],"blood":[114],"pressure":[115],"recorded":[117],"months.Variables":[120],"between":[121],"at":[123],"enrollment":[124],"within":[126],"over":[128],"visits":[129],"compared":[131]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2025-10-10T00:00:00"}
