{"id":"https://openalex.org/W17003264","doi":null,"title":"Myocardial contrast echocardiography: examination of intracoronary injections, microbubble diameters, and video-intensity decay.","display_name":"Myocardial contrast echocardiography: examination of intracoronary injections, microbubble diameters, and video-intensity decay.","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W17003264","mag":"17003264","pmid":"https://pubmed.ncbi.nlm.nih.gov/3451752"},"language":"en","primary_location":{"id":"pmid:3451752","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3451752","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiologic imaging","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008079426","display_name":"Steven B. Feinstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S B Feinstein","raw_affiliation_strings":["Department of Medicine, University of Chicago, Illinois 60637"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Chicago, Illinois 60637","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103145686","display_name":"Kenneth Ong","orcid":"https://orcid.org/0000-0001-7410-7992","observed_orcids":["https://orcid.org/0000-0001-7410-7992"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Ong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091888801","display_name":"Howard M. Staniloff","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H M Staniloff","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010163561","display_name":"Y Fujibayashi","orcid":"https://orcid.org/0000-0002-9240-6651","observed_orcids":["https://orcid.org/0000-0002-9240-6651"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Fujibayashi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019291926","display_name":"Werner Zwehl","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Zwehl","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040270475","display_name":"Samuel Meerbaum","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Meerbaum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5105125188","display_name":"Pravin M. Shah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P M Shah","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.5166,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.91224363,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":"1","first_page":"12","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.6567000150680542,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.6567000150680542,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.2484000027179718,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.06960000097751617,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myocardial-contrast-echocardiography","display_name":"myocardial contrast echocardiography","score":0.9980000257492065},{"id":"https://openalex.org/keywords/microbubbles","display_name":"microbubbles","score":0.8069999814033508},{"id":"https://openalex.org/keywords/intracoronary-injection","display_name":"intracoronary injection","score":0.8880000114440918},{"id":"https://openalex.org/keywords/myocardial-blood-flow","display_name":"myocardial blood flow","score":0.8949999809265137},{"id":"https://openalex.org/keywords/sorbitol","display_name":"sorbitol","score":0.6639999747276306},{"id":"https://openalex.org/keywords/d-glucose","display_name":"D-glucose","score":0.984000027179718},{"id":"https://openalex.org/keywords/time-intensity-curve","display_name":"time-intensity curve","score":0.6269999742507935},{"id":"https://openalex.org/keywords/videodensitometry","display_name":"videodensitometry","score":0.7760000228881836},{"id":"https://openalex.org/keywords/image-processing","display_name":"image processing","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6556816101074219},{"id":"https://openalex.org/C93038891","wikidata":"https://www.wikidata.org/wiki/Q1061524","display_name":"Intensity (physics)","level":2,"score":0.6502022743225098},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5939717888832092},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.5786590576171875},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.5579085946083069},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.4575464129447937},{"id":"https://openalex.org/C138010386","wikidata":"https://www.wikidata.org/wiki/Q6804531","display_name":"Mechanical index","level":4,"score":0.45096567273139954},{"id":"https://openalex.org/C64012434","wikidata":"https://www.wikidata.org/wiki/Q6839290","display_name":"Microbubbles","level":3,"score":0.44215282797813416},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4064599871635437},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.34102335572242737},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.06042376160621643},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003720","descriptor_name":"Densitometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D007269","descriptor_name":"Injections, Intra-Arterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014741","descriptor_name":"Video Recording","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3451752","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3451752","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiologic imaging","raw_type":"Journal Article"},{"id":"mag:17003264","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3451752","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2014261136","https://openalex.org/W2033349147","https://openalex.org/W1985304832","https://openalex.org/W2054314681","https://openalex.org/W1968084225","https://openalex.org/W2026077214","https://openalex.org/W2416381070","https://openalex.org/W2049232305","https://openalex.org/W1978301568","https://openalex.org/W2466473719"],"abstract_inverted_index":{"Contrast":[0],"echocardiographic":[1,156,169],"assessment":[2,157],"of":[3,11,34,45,139,158,166,182],"blood":[4,160],"flow":[5],"within":[6],"the":[7,78,99,106,183],"myocardium":[8],"requires":[9],"standardization":[10],"contrast":[12,19,65,146,167],"agents":[13],"and":[14,23,37,60,63,116,123,132,162],"echo":[15,47,66,145,180],"image":[16],"analysis.":[17],"Sonicated":[18,113],"solutions":[20,54,119,147],"containing":[21],"small":[22,149],"relatively":[24],"stable":[25],"microbubble":[26,150],"ultrasound":[27],"reflectors":[28],"were":[29,68],"injected":[30],"into":[31],"coronary":[32],"arteries":[33],"five":[35],"dogs,":[36],"a":[38],"newly":[39],"developed":[40],"computer":[41],"assisted":[42],"densitometric":[43],"analysis":[44,165,181],"myocardial":[46,64,102,159],"intensity":[48,81,185],"decay":[49,74],"was":[50],"examined.":[51],"The":[52,137],"sonicated":[53,95],"included":[55],"sorbitol":[56,96],"70%,":[57,59],"dextrose":[58,61,114,117],"50%,":[62],"data":[67],"analyzed":[69],"by":[70],"applying":[71],"an":[72],"exponential":[73],"index":[75],"(T-1/2)":[76],"to":[77,154],"digitized":[79],"time":[80,104,184],"curves":[82],"obtained":[83],"with":[84,105,148,174],"videodensitometric":[85],"techniques.":[86],"In":[87],"30":[88],"intracoronary":[89],"injections":[90],"selected":[91],"for":[92],"further":[93],"analysis,":[94],"70%":[97,115],"demonstrated":[98],"most":[100],"physiologic":[101],"transit":[103,126],"smallest":[107],"variability":[108],"(6.0":[109],"+/-":[110,129,134],"2.0":[111],"seconds).":[112,136],"50%":[118],"exhibited":[120],"significantly":[121],"prolonged":[122],"more":[124],"variable":[125],"times":[127],"(11.4":[128],"4.0":[130],"seconds":[131],"13.9":[133],"5.0":[135],"results":[138],"this":[140],"study":[141],"suggest":[142],"that":[143,163],"appropriate":[144],"diameters":[151],"are":[152],"critical":[153],"satisfactory":[155],"flow,":[161],"objective":[164],"two-dimensional":[168],"images":[170],"can":[171],"be":[172],"achieved":[173],"computer-assisted":[175],"videodensity":[176],"algorithms":[177],"featuring":[178],"standardized":[179],"data.":[186]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}