{"id":"https://openalex.org/W1694866441","doi":null,"title":"Plant Major Intrinsic Proteins - natural variation and evolution","display_name":"Plant Major Intrinsic Proteins - natural variation and evolution","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W1694866441","mag":"1694866441"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.937.9215","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.937.9215","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://lup.lub.lu.se/luur/download?fileOId%3D1714730%26func%3DdownloadFile%26recordOId%3D1714727","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://lup.lub.lu.se/record/1714727","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035462032","display_name":"Jonas \u00c5H Danielson","orcid":"https://orcid.org/0000-0001-7000-5032","observed_orcids":["https://orcid.org/0000-0001-7000-5032"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jonas \u00c5H Danielson","raw_affiliation_strings":["Biochemistry and Structural Biology"],"raw_orcid":"https://orcid.org/0000-0001-7000-5032","affiliations":[{"raw_affiliation_string":"Biochemistry and Structural Biology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5035462032"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2124,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.46651826,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11247","display_name":"Plant nutrient uptake and metabolism","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/major-intrinsic-proteins","display_name":"major intrinsic proteins","score":0.8579999804496765},{"id":"https://openalex.org/keywords/aquaporins","display_name":"aquaporins","score":0.9919999837875366},{"id":"https://openalex.org/keywords/plant-aquaporins","display_name":"plant aquaporins","score":0.8450000286102295},{"id":"https://openalex.org/keywords/natural-variability","display_name":"natural variation","score":0.6159999966621399},{"id":"https://openalex.org/keywords/protein-evolution","display_name":"protein evolution","score":0.7580000162124634},{"id":"https://openalex.org/keywords/protein-isoforms","display_name":"protein isoforms","score":0.5849999785423279},{"id":"https://openalex.org/keywords/substrate-specificity","display_name":"substrate specificity","score":0.6100000143051147},{"id":"https://openalex.org/keywords/membrane-transport","display_name":"membrane transport","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.715299129486084},{"id":"https://openalex.org/C154280991","wikidata":"https://www.wikidata.org/wiki/Q623090","display_name":"Aquaporin","level":2,"score":0.6911680698394775},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6000100374221802},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.5933658480644226},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5898866653442383},{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.576960563659668},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.46967893838882446},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.43642595410346985},{"id":"https://openalex.org/C5911399","wikidata":"https://www.wikidata.org/wiki/Q2278983","display_name":"Gene family","level":4,"score":0.4262637495994568},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38987815380096436},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31008344888687134},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2875653803348541},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.16571369767189026},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.11411258578300476}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.937.9215","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.937.9215","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://lup.lub.lu.se/luur/download?fileOId%3D1714730%26func%3DdownloadFile%26recordOId%3D1714727","raw_type":"text"},{"id":"pmh:oai:lup.lub.lu.se:6980a543-6157-404a-ab50-b0096a69774a","doi":null,"is_oa":true,"landing_page_url":"https://lup.lub.lu.se/record/1714727","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:1694866441","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/search/publication/6980a543-6157-404a-ab50-b0096a69774a","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:lup.lub.lu.se:6980a543-6157-404a-ab50-b0096a69774a","doi":null,"is_oa":true,"landing_page_url":"https://lup.lub.lu.se/record/1714727","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":118,"referenced_works":["https://openalex.org/W61051756","https://openalex.org/W238259533","https://openalex.org/W1492555480","https://openalex.org/W1501694644","https://openalex.org/W1512016817","https://openalex.org/W1546866132","https://openalex.org/W1565791215","https://openalex.org/W1635447770","https://openalex.org/W1639718205","https://openalex.org/W1781851364","https://openalex.org/W1845114139","https://openalex.org/W1894904419","https://openalex.org/W1947778485","https://openalex.org/W1965624710","https://openalex.org/W1965927041","https://openalex.org/W1969501907","https://openalex.org/W1971718332","https://openalex.org/W1973950074","https://openalex.org/W1977697815","https://openalex.org/W1978354625","https://openalex.org/W1981321045","https://openalex.org/W1981634750","https://openalex.org/W1984075431","https://openalex.org/W1984539250","https://openalex.org/W1984711473","https://openalex.org/W1986765471","https://openalex.org/W1988171585","https://openalex.org/W1988857299","https://openalex.org/W1991977674","https://openalex.org/W1993727030","https://openalex.org/W1995572705","https://openalex.org/W1996119897","https://openalex.org/W1997542785","https://openalex.org/W1998770029","https://openalex.org/W1999340580","https://openalex.org/W2000162975","https://openalex.org/W2001286057","https://openalex.org/W2004000039","https://openalex.org/W2004863008","https://openalex.org/W2011357793","https://openalex.org/W2012164145","https://openalex.org/W2013883162","https://openalex.org/W2013920324","https://openalex.org/W2017434302","https://openalex.org/W2018641191","https://openalex.org/W2018857407","https://openalex.org/W2019650166","https://openalex.org/W2025935801","https://openalex.org/W2029360750","https://openalex.org/W2029708136","https://openalex.org/W2030217560","https://openalex.org/W2032424722","https://openalex.org/W2035294304","https://openalex.org/W2039150510","https://openalex.org/W2040211932","https://openalex.org/W2042447779","https://openalex.org/W2042458891","https://openalex.org/W2043247882","https://openalex.org/W2046014422","https://openalex.org/W2048743237","https://openalex.org/W2050679273","https://openalex.org/W2052922251","https://openalex.org/W2053693922","https://openalex.org/W2055285141","https://openalex.org/W2056850009","https://openalex.org/W2057701166","https://openalex.org/W2061319823","https://openalex.org/W2063733074","https://openalex.org/W2065803545","https://openalex.org/W2072540327","https://openalex.org/W2078936885","https://openalex.org/W2084304818","https://openalex.org/W2086747277","https://openalex.org/W2086933987","https://openalex.org/W2088677010","https://openalex.org/W2089361501","https://openalex.org/W2092252893","https://openalex.org/W2092398899","https://openalex.org/W2092436229","https://openalex.org/W2093282042","https://openalex.org/W2097187005","https://openalex.org/W2098641326","https://openalex.org/W2098769040","https://openalex.org/W2100979570","https://openalex.org/W2104636880","https://openalex.org/W2105525923","https://openalex.org/W2106265368","https://openalex.org/W2109311481","https://openalex.org/W2109632095","https://openalex.org/W2111126472","https://openalex.org/W2111386845","https://openalex.org/W2112670544","https://openalex.org/W2118061859","https://openalex.org/W2122650823","https://openalex.org/W2123099945","https://openalex.org/W2131885732","https://openalex.org/W2132492378","https://openalex.org/W2135719986","https://openalex.org/W2139156910","https://openalex.org/W2140674348","https://openalex.org/W2140954431","https://openalex.org/W2141207650","https://openalex.org/W2142364749","https://openalex.org/W2142543069","https://openalex.org/W2144843396","https://openalex.org/W2148624161","https://openalex.org/W2149104046","https://openalex.org/W2152493361","https://openalex.org/W2154702782","https://openalex.org/W2155158841","https://openalex.org/W2155935848","https://openalex.org/W2157363634","https://openalex.org/W2158451653","https://openalex.org/W2163153928","https://openalex.org/W2165281420","https://openalex.org/W2167057772","https://openalex.org/W2169155960","https://openalex.org/W2170344718"],"related_works":["https://openalex.org/W2140674348","https://openalex.org/W748395155","https://openalex.org/W821314461","https://openalex.org/W7097529106","https://openalex.org/W6912853303","https://openalex.org/W1984581415","https://openalex.org/W987230794","https://openalex.org/W1740053962","https://openalex.org/W2470558202","https://openalex.org/W2138734970"],"abstract_inverted_index":{"Major":[0],"Intrinsic":[1],"Proteins":[2],"(MIPs,":[3],"also":[4,210,292],"called":[5],"Aquaporins,":[6],"AQPs)":[7],"are":[8,36],"channel":[9],"forming":[10],"membrane":[11],"proteins.":[12],"Although":[13],"initially":[14],"functionally":[15],"characterized":[16],"and":[17,43,63,74,85,143,259,265,282],"named":[18],"after":[19],"their":[20],"water":[21],"channeling":[22],"property":[23],"in":[24,38,98,110,129,140,195,206,219,254,260,293],"human":[25],"red":[26],"blood":[27],"cells,":[28],"it":[29],"has":[30],"become":[31],"increasingly":[32],"evident":[33],"that":[34,105],"MIPs":[35,53,81,106,116,279],"present":[37,291],"all":[39],"types":[40],"of":[41,47,70,77,114,126,152,185,215,236,243,272,278,285],"organisms":[42],"transport":[44,72],"a":[45,55,60,83,124,165,237,244],"variety":[46],"small,":[48],"uncharged":[49],"molecules":[50],"besides":[51],"water.":[52],"have":[54,107,117,168],"highly":[56],"conserved":[57],"structure":[58],"with":[59,89],"constriction":[61],"region":[62],"electrostatic":[64],"repulsion":[65],"filter":[66,131],"allowing":[67],"the":[68,102,112,130,186,213,216,234,241,250,255,286],"combination":[69],"high":[71],"rate":[73],"selectivity,":[75],"characteristic":[76],"MIPs.":[78],"In":[79],"plants,":[80,111,220],"form":[82],"large":[84,166],"varied":[86],"protein":[87],"family,":[88],"roughly":[90],"three":[91],"times":[92],"as":[93,96,133,135,158,198,233],"many":[94],"isoforms":[95,154],"found":[97,281],"animals.":[99],"Even":[100],"though":[101],"abundance":[103],"implies":[104],"important":[108],"functions":[109,151],"roles":[113],"individual":[115],"so":[118],"far":[119],"only":[120],"been":[121],"described":[122],"for":[123,145,226],"handful":[125],"isoforms.":[127],"Variations":[128],"regions":[132],"well":[134],"experimental":[136],"data,":[137],"suggest":[138],"differences":[139,194,205],"substrate":[141],"specificities":[142],"localization":[144],"different":[146,153,262],"MIP":[147,207,217,252],"subfamilies.":[148],"However":[149],"actual":[150],"remain":[155],"largely":[156],"unknown":[157],"traditional":[159],"knock":[160],"out/knock":[161],"down":[162],"experiments":[163],"to":[164,170,191,204,221,230,270],"extent":[167],"failed":[169],"reveal":[171],"any":[172],"clear":[173],"phenotypes.":[174],"Using":[175],"another":[176],"approach,":[177],"we":[178,248],"used":[179],"naturally":[180],"occurring":[181],"genetic":[182],"variants":[183],"(accessions)":[184],"model":[187],"plant":[188,288],"Arabidopsis":[189],"thaliana":[190],"see":[192,222],"if":[193,223],"traits,":[196],"such":[197,232],"drought":[199],"tolerance,":[200],"could":[201,225],"be":[202,228],"linked":[203,229],"regulation.":[208],"We":[209],"looked":[211],"at":[212],"evolution":[214],"family":[218,253],"this":[224],"example":[227],"events":[231],"emergence":[235],"vascular":[238],"system":[239],"or":[240],"development":[242],"terrestrial":[245],"lifestyle.":[246],"Therefore":[247],"identified":[249],"whole":[251],"moss":[256],"Physcomitrella":[257],"patens":[258],"nine":[261],"green":[263],"algae":[264],"investigated":[266],"how":[267],"these":[268,294],"relate":[269],"those":[271],"higher":[273,287],"plants.":[274,296],"An":[275],"amazing":[276],"diversity":[277],"was":[280],"surprisingly":[283],"some":[284],"subfamilies":[289],"were":[290],"simple":[295]},"counts_by_year":[{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-08-26T07:47:46.906454","created_date":"2016-06-24T00:00:00"}
