{"id":"https://openalex.org/W169065712","doi":null,"title":"Predicting the presence of choledocholithiasis in patients with symptomatic cholelithiasis.","display_name":"Predicting the presence of choledocholithiasis in patients with symptomatic cholelithiasis.","publication_year":1996,"publication_date":"1996-04-01","ids":{"openalex":"https://openalex.org/W169065712","mag":"169065712","pmid":"https://pubmed.ncbi.nlm.nih.gov/8677945"},"language":"en","primary_location":{"id":"pmid:8677945","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8677945","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Comparative Study"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040743209","display_name":"Jane E. Onken","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J E Onken","raw_affiliation_strings":["Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003406005","display_name":"Scott R. Brazer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S R Brazer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071495455","display_name":"Glenn M. Eisen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G M Eisen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013259507","display_name":"David Michael Williams","orcid":"https://orcid.org/0000-0001-9472-6168","observed_orcids":["https://orcid.org/0000-0001-9472-6168"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D M Williams","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077959545","display_name":"Ernest P. Bouras","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E P Bouras","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071955362","display_name":"Elizabeth R. DeLong","orcid":"https://orcid.org/0000-0001-7166-1867","observed_orcids":["https://orcid.org/0000-0001-7166-1867"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E R DeLong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110246285","display_name":"Terrie Long","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T T Long","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024112281","display_name":"Frank S. Pancotto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F S Pancotto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111480123","display_name":"Deborah L. Rhodes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D L Rhodes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5008463028","display_name":"Peter B. Cotton","orcid":"https://orcid.org/0000-0001-5077-2517","observed_orcids":["https://orcid.org/0000-0001-5077-2517"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P B Cotton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0183,"has_fulltext":false,"cited_by_count":136,"citation_normalized_percentile":{"value":0.85395691,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"91","issue":"4","first_page":"762","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13697","display_name":"Biliary and Gastrointestinal Fistulas","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/choledocholithiasis","display_name":"choledocholithiasis","score":1.0},{"id":"https://openalex.org/keywords/symptomatic-cholelithiasis","display_name":"symptomatic cholelithiasis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/cholecystectomy","display_name":"cholecystectomy","score":0.8970000147819519},{"id":"https://openalex.org/keywords/preoperative-prediction","display_name":"preoperative prediction","score":0.8050000071525574},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9629999995231628},{"id":"https://openalex.org/keywords/bilirubin","display_name":"bilirubin","score":0.9120000004768372},{"id":"https://openalex.org/keywords/common-bile-duct-diameter","display_name":"common bile duct diameter","score":0.9670000076293945},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.8799999952316284},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.9700000286102295},{"id":"https://openalex.org/keywords/predictive-model","display_name":"prediction model","score":0.6140000224113464},{"id":"https://openalex.org/keywords/cholangiography","display_name":"cholangiography","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8906475901603699},{"id":"https://openalex.org/C2777513400","wikidata":"https://www.wikidata.org/wiki/Q104219","display_name":"Bilirubin","level":2,"score":0.7527165412902832},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.7223606109619141},{"id":"https://openalex.org/C2776641081","wikidata":"https://www.wikidata.org/wiki/Q638774","display_name":"Cholecystectomy","level":2,"score":0.6795480251312256},{"id":"https://openalex.org/C2776884468","wikidata":"https://www.wikidata.org/wiki/Q1263617","display_name":"Common bile duct","level":2,"score":0.6743900179862976},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.6626981496810913},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6350281238555908},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.598237931728363},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.547387957572937},{"id":"https://openalex.org/C2779388726","wikidata":"https://www.wikidata.org/wiki/Q272714","display_name":"Gallstones","level":2,"score":0.5119770765304565},{"id":"https://openalex.org/C2777969384","wikidata":"https://www.wikidata.org/wiki/Q17011974","display_name":"Elevated alkaline phosphatase","level":4,"score":0.4972379505634308},{"id":"https://openalex.org/C2779777945","wikidata":"https://www.wikidata.org/wiki/Q851111","display_name":"Bile duct","level":2,"score":0.4293382465839386},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33456674218177795},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.2840218245983124},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002763","descriptor_name":"Cholecystectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002769","descriptor_name":"Cholelithiasis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D002769","descriptor_name":"Cholelithiasis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002769","descriptor_name":"Cholelithiasis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011300","descriptor_name":"Preoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017081","descriptor_name":"Cholecystectomy, Laparoscopic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042882","descriptor_name":"Gallstones","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D042882","descriptor_name":"Gallstones","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D042882","descriptor_name":"Gallstones","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:8677945","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8677945","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Comparative Study"},{"id":"mag:169065712","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8677945","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4225285138","https://openalex.org/W4306785105","https://openalex.org/W2683176949","https://openalex.org/W1480172798","https://openalex.org/W4415537742","https://openalex.org/W4308772143","https://openalex.org/W2002563744","https://openalex.org/W2284808828","https://openalex.org/W7167234412","https://openalex.org/W4396698238"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Accurate":[1,215],"preoperative":[2,107,225],"prediction":[3],"of":[4,52,62,78,86,111,153,191,217,237],"choledocholithiasis":[5,29,87,210,218],"is":[6],"essential":[7],"in":[8,30,150],"order":[9],"to":[10,23,40,203,257],"minimize":[11],"patient":[12],"risk":[13,26,219],"and":[14,39,71,95,105,124,131,142,170,186,232],"curtail":[15],"health":[16],"care":[17],"expenditures.":[18],"This":[19],"study":[20],"was":[21,148,206],"designed":[22],"identify":[24],"independent":[25,189],"factors":[27],"for":[28,36,98,109],"patients":[31,55,80,245],"who":[32,56,249],"had":[33,57,81],"undergone":[34,58],"cholecystectomy":[35,59],"symptomatic":[37,247],"cholelithiasis":[38,248],"develop":[41],"a":[42],"predictive":[43],"model":[44,195,205,239],"based":[45],"on":[46],"those":[47,244],"factors.":[48],"METHODS:":[49],"The":[50],"charts":[51],"1264":[53],"consecutive":[54],"at":[60],"one":[61],"three":[63],"North":[64],"Carolina":[65],"hospitals":[66],"between":[67],"January":[68],"1,":[69],"1989":[70],"December":[72],"31,":[73],"1991":[74],"were":[75,96,133],"reviewed;":[76],"465":[77,155],"these":[79,197],"confirmed":[82,149],"presence":[83],"or":[84],"absence":[85],"by":[88],"cholangiography":[89],"and/or":[90],"common":[91,125,162,179,227],"bile":[92,126,163,180,228],"duct":[93,127,164,181,229],"exploration":[94],"eligible":[97,156],"analysis.":[99],"Candidate":[100],"predictor":[101],"variables":[102,198],"included":[103],"age":[104,171,187],"maximum":[106,224],"values":[108],"each":[110],"the":[112,154,204,238],"following:":[113],"temperature,":[114,167],"alkaline":[115,168,184,233],"phosphatase,":[116,169,185],"bilirubin,":[117,161,178,226],"AST,":[118,166,183,231],"amylase,":[119],"white":[120],"blood":[121],"cell":[122],"count,":[123],"diameter.":[128],"Model":[129],"development":[130],"validation":[132],"conducted":[134],"using":[135,223],"standard":[136],"data-splitting":[137],"(60%":[138],"\"training,\"":[139],"40%":[140],"\"test\")":[141],"logistic":[143],"regression":[144],"techniques.":[145],"RESULTS:":[146],"Choledocholithiasis":[147],"115":[151],"(25%)":[152],"patients.":[157],"Univariate":[158],"analysis":[159,175],"identified":[160,177],"diameter,":[165,182,230],"as":[172,188],"predictors.":[173],"Multivariable":[174],"subsequently":[176],"predictors":[190],"choledocholithiasis.":[192,259],"A":[193],"final":[194],"containing":[196],"(except":[199],"age,":[200],"whose":[201],"contribution":[202],"small)":[207],"accurately":[208],"predicted":[209],"(c-index":[211],"=":[212],"0.76).":[213],"CONCLUSIONS:":[214],"estimates":[216],"can":[220],"be":[221],"made":[222],"phosphatase":[234],"values.":[235],"Use":[236],"may":[240],"help":[241],"physicians":[242],"select":[243],"with":[246],"would":[250],"most":[251],"likely":[252],"benefit":[253],"from":[254],"further":[255],"investigation":[256],"exclude":[258]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}