{"id":"https://openalex.org/W1669468643","doi":null,"title":"Cognitive behavior therapy for treatment-refractory panic disorder.","display_name":"Cognitive behavior therapy for treatment-refractory panic disorder.","publication_year":1994,"publication_date":"1994-05-01","ids":{"openalex":"https://openalex.org/W1669468643","mag":"1669468643","pmid":"https://pubmed.ncbi.nlm.nih.gov/8071270"},"language":"en","primary_location":{"id":"pmid:8071270","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8071270","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Clinical Trial"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065758533","display_name":"Mark H. Pollack","orcid":"https://orcid.org/0000-0001-7240-2162","observed_orcids":["https://orcid.org/0000-0001-7240-2162"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M H Pollack","raw_affiliation_strings":["Clinical Psychopharmacology Unit, Harvard Medical School, Massachusetts General Hospital, Boston 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Psychopharmacology Unit, Harvard Medical School, Massachusetts General Hospital, Boston 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063995344","display_name":"Michael W. Otto","orcid":"https://orcid.org/0000-0002-8915-7578","observed_orcids":["https://orcid.org/0000-0002-8915-7578"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M W Otto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013039395","display_name":"Susan P. Kaspi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S P Kaspi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016980419","display_name":"Paul Graves Hammerness","orcid":"https://orcid.org/0009-0004-6579-0573","observed_orcids":["https://orcid.org/0009-0004-6579-0573"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P G Hammerness","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5104363844","display_name":"Jerrold F. Rosenbaum","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J F Rosenbaum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.085,"has_fulltext":false,"cited_by_count":91,"citation_normalized_percentile":{"value":0.94696707,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"55","issue":"5","first_page":"200","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13272","display_name":"Psychological Treatments and Assessments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10214","display_name":"Psychotherapy Techniques and Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"cognitive behavioral therapy","score":0.8579999804496765},{"id":"https://openalex.org/keywords/panic-disorder","display_name":"panic disorder","score":0.984000027179718},{"id":"https://openalex.org/keywords/group-therapy","display_name":"group therapy","score":0.6520000100135803},{"id":"https://openalex.org/keywords/drug-withdrawal","display_name":"drug withdrawal","score":0.34599998593330383},{"id":"https://openalex.org/keywords/adjunctive-psychotherapy","display_name":"adjunctive psychotherapy","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C2777529043","wikidata":"https://www.wikidata.org/wiki/Q741713","display_name":"Panic disorder","level":3,"score":0.8693175315856934},{"id":"https://openalex.org/C2780712732","wikidata":"https://www.wikidata.org/wiki/Q208450","display_name":"Panic","level":3,"score":0.709811806678772},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.6741495728492737},{"id":"https://openalex.org/C2779477915","wikidata":"https://www.wikidata.org/wiki/Q13693745","display_name":"Cognitive therapy","level":3,"score":0.5360659956932068},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5023839473724365},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.458361953496933},{"id":"https://openalex.org/C2781265626","wikidata":"https://www.wikidata.org/wiki/Q1147152","display_name":"Cognitive behavioral therapy","level":3,"score":0.44731175899505615},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43994051218032837},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.42454826831817627},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4190061390399933},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.25757482647895813},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22919520735740662}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000525","descriptor_name":"Alprazolam","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002998","descriptor_name":"Clonazepam","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005473","descriptor_name":"Fluoxetine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007099","descriptor_name":"Imipramine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011615","descriptor_name":"Psychotherapy, Group","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015928","descriptor_name":"Cognitive Behavioral Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016584","descriptor_name":"Panic Disorder","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8071270","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8071270","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Clinical Trial"},{"id":"mag:1669468643","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8071270","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7900000214576721}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G1892577090","display_name":"FACULTY SCHOLAR AWARD IN DEPRESSION AND ANXIETY (PSYCHIA","funder_award_id":"1t01mh019600-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2056321351","https://openalex.org/W2090988386","https://openalex.org/W7014170238","https://openalex.org/W1977456023","https://openalex.org/W1979264575","https://openalex.org/W2089814289","https://openalex.org/W4414462334","https://openalex.org/W2093404642","https://openalex.org/W2019573594","https://openalex.org/W2019704217"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"purpose":[2],"of":[3,12,19,32,42,50,60,75,89,102,108,119,124,136,151,180,220],"this":[4],"pilot":[5],"study":[6,173],"is":[7,174],"to":[8,29,54,78,95,111,212],"assess":[9,79],"the":[10,17,90,125,149,152,218],"efficacy":[11],"cognitive":[13,62,153,221],"behavior":[14,63,154,222],"therapy":[15,155],"for":[16,46],"treatment":[18,48],"patients":[20,37,92,126,140,184,202],"with":[21,38,58,176,185,203],"panic":[22,43,82,163,186,204],"disorder":[23,44,187,205],"who":[24,206],"experience":[25],"an":[26,51,98,132],"incomplete":[27,52],"response":[28,53],"a":[30,39,73,109,142,160,177],"trial":[31,101,135],"pharmacotherapy.":[33],"METHOD:":[34],"Fifteen":[35],"consecutive":[36],"DSM-III-R":[40],"diagnosis":[41],"referred":[45],"further":[47],"because":[49,107],"pharmacotherapy":[55],"were":[56,66,93,127],"treated":[57],"12-weeks":[59],"group":[61],"therapy.":[64,223],"Patients":[65],"evaluated":[67],"at":[68,72,104,129,148,169],"baseline,":[69,105],"endpoint,":[70],"and":[71,85,192],"mean":[74],"2-months'":[76],"follow-up":[77],"changes":[80],"in":[81,145,162],"attack":[83,164],"frequency":[84],"global":[86,146],"outcome.":[87],"Eight":[88],"15":[91],"deemed":[94],"have":[96],"received":[97],"inadequate":[99,195],"prior":[100,134],"medication":[103,116],"mainly":[106],"desire":[110],"control":[112],"their":[113],"symptoms":[114],"without":[115],"or":[117,210],"fear":[118],"withdrawal":[120],"and/or":[121],"addiction.":[122],"Seven":[123],"symptomatic":[128,189],"baseline":[130],"despite":[131],"adequate":[133],"medication.":[137],"RESULTS:":[138],"Overall,":[139],"experienced":[141],"significant":[143],"improvement":[144],"function":[147],"end":[150],"intervention,":[156],"as":[157,159],"well":[158],"decrease":[161],"frequency.":[165],"Improvement":[166],"was":[167],"maintained":[168],"follow-up.":[170],"CONCLUSION:":[171],"This":[172],"consistent":[175],"growing":[178],"body":[179],"evidence":[181],"that":[182,201],"many":[183],"remain":[188],"over":[190],"time":[191],"are":[193,207],"receiving":[194],"pharmacotherapeutic":[196,213],"treatment.":[197],"Further,":[198],"we":[199],"observed":[200],"incompletely":[208],"responsive":[209],"resistant":[211],"management":[214],"may":[215],"benefit":[216],"from":[217],"addition":[219]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}