{"id":"https://openalex.org/W1666517633","doi":null,"title":"Inflammatory Monocytes in Bipolar Disorder and Related Endocrine Autoimmune Diseases","display_name":"Inflammatory Monocytes in Bipolar Disorder and Related Endocrine Autoimmune Diseases","publication_year":2009,"publication_date":"2009-02-25","ids":{"openalex":"https://openalex.org/W1666517633","mag":"1666517633"},"language":"en","primary_location":{"id":"pmh:oai:repub.eur.nl:14920","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/14920","pdf_url":"http://repub.eur.nl/pub/14920","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://repub.eur.nl/pub/14920","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085859404","display_name":"Roos C. Padmos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Roos C. Padmos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5085859404"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bipolar-disorder","display_name":"bipolar disorder","score":0.8759999871253967},{"id":"https://openalex.org/keywords/inflammatory-monocytes","display_name":"inflammatory monocytes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/mood-disorders","display_name":"mood disorders","score":0.5569999814033508},{"id":"https://openalex.org/keywords/manic-episodes","display_name":"manic episodes","score":0.7770000100135803},{"id":"https://openalex.org/keywords/depressive-episodes","display_name":"depressive episodes","score":0.9359999895095825},{"id":"https://openalex.org/keywords/hypomania","display_name":"hypomania","score":0.593999981880188},{"id":"https://openalex.org/keywords/monocyte-inflammation","display_name":"monocyte inflammation","score":0.4099999964237213}],"concepts":[{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.7572120428085327},{"id":"https://openalex.org/C2776809841","wikidata":"https://www.wikidata.org/wiki/Q185935","display_name":"Mania","level":4,"score":0.7352281808853149},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6748085021972656},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.6187869310379028},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.5863588452339172},{"id":"https://openalex.org/C2776202747","wikidata":"https://www.wikidata.org/wiki/Q3064951","display_name":"Psychomotor retardation","level":3,"score":0.5035631060600281},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.49535953998565674},{"id":"https://openalex.org/C2778567577","wikidata":"https://www.wikidata.org/wiki/Q188611","display_name":"Hypomania","level":5,"score":0.45869749784469604},{"id":"https://openalex.org/C2776153860","wikidata":"https://www.wikidata.org/wiki/Q394129","display_name":"Psychomotor agitation","level":2,"score":0.44886600971221924},{"id":"https://openalex.org/C2781210005","wikidata":"https://www.wikidata.org/wiki/Q6738337","display_name":"Major depressive episode","level":3,"score":0.43121108412742615},{"id":"https://openalex.org/C2776571617","wikidata":"https://www.wikidata.org/wiki/Q2657784","display_name":"Atypical depression","level":3,"score":0.4217371940612793},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.33483070135116577},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23156163096427917},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:repub.eur.nl:14920","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/14920","pdf_url":"http://repub.eur.nl/pub/14920","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:eur:oai:pure.eur.nl:publications/8cf9361f-a9ae-46ac-b010-bc9c09231808","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/8cf9361f-a9ae-46ac-b010-bc9c09231808","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:eur:oai:repub.eur.nl:14920","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/14920","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"mag:1666517633","doi":null,"is_oa":false,"landing_page_url":"https://repub.eur.nl/pub/14920/090225_Padmos,%20Roos%20Carlijn.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repub.eur.nl:14920","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/14920","pdf_url":"http://repub.eur.nl/pub/14920","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310094","display_name":"University of Washington","ror":"https://ror.org/00cvxb145"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1666517633.pdf","grobid_xml":"https://content.openalex.org/works/W1666517633.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W561643306","https://openalex.org/W1533308479","https://openalex.org/W1610651662","https://openalex.org/W1918804830","https://openalex.org/W1935730507","https://openalex.org/W1964077915","https://openalex.org/W1986222699","https://openalex.org/W2001860298","https://openalex.org/W2008037802","https://openalex.org/W2010910086","https://openalex.org/W2019806256","https://openalex.org/W2019928465","https://openalex.org/W2022573391","https://openalex.org/W2023194882","https://openalex.org/W2024342703","https://openalex.org/W2025883568","https://openalex.org/W2028109077","https://openalex.org/W2038242685","https://openalex.org/W2049808835","https://openalex.org/W2051930316","https://openalex.org/W2051978541","https://openalex.org/W2054843309","https://openalex.org/W2055429430","https://openalex.org/W2062741837","https://openalex.org/W2065538277","https://openalex.org/W2066457796","https://openalex.org/W2070760429","https://openalex.org/W2079285312","https://openalex.org/W2081640356","https://openalex.org/W2086109807","https://openalex.org/W2097703150","https://openalex.org/W2099439812","https://openalex.org/W2104440648","https://openalex.org/W2107037828","https://openalex.org/W2107423916","https://openalex.org/W2114122082","https://openalex.org/W2118985824","https://openalex.org/W2119756897","https://openalex.org/W2120758187","https://openalex.org/W2121371688","https://openalex.org/W2129192684","https://openalex.org/W2131803478","https://openalex.org/W2132211535","https://openalex.org/W2133658521","https://openalex.org/W2134117346","https://openalex.org/W2142972284","https://openalex.org/W2145336951","https://openalex.org/W2145731558","https://openalex.org/W2149774728","https://openalex.org/W2150524024","https://openalex.org/W2157865652","https://openalex.org/W2158152166","https://openalex.org/W2159087408","https://openalex.org/W2160754803","https://openalex.org/W2161153023","https://openalex.org/W2161400670","https://openalex.org/W2162066663","https://openalex.org/W2165571979","https://openalex.org/W2170250764","https://openalex.org/W2170357921","https://openalex.org/W2178355872","https://openalex.org/W2335841576","https://openalex.org/W2406423760","https://openalex.org/W2418912569","https://openalex.org/W2573651074"],"related_works":["https://openalex.org/W4320027388","https://openalex.org/W4251098653","https://openalex.org/W4252058525","https://openalex.org/W3165042115","https://openalex.org/W6920329499","https://openalex.org/W4224903018","https://openalex.org/W4238239257","https://openalex.org/W1489814357","https://openalex.org/W4388360328","https://openalex.org/W7098250019"],"abstract_inverted_index":{"Bipolar":[0],"disorder":[1,166],"(also":[2],"called":[3],"manic-depressive":[4,15],"illness)":[5],"is":[6,29,55,104,113,172],"one":[7,175],"of":[8,74,77,144,153],"the":[9,24,50,99,114,132],"major":[10],"mood":[11,48,63,129],"disorders.":[12],"The":[13],"term":[14],"illness":[16,35],"was":[17],"introduced":[18],"by":[19,57,68,174],"Emil":[20],"Kraepelin":[21],"(1856-1926)":[22],"in":[23,30,90],"late":[25],"nineteenth":[26],"century.1":[27],"It":[28],"most":[31],"patients":[32],"a":[33,69,117,123,127,182],"chronic":[34],"with":[36,44,46,92,107,116,122,131],"recurrent":[37],"manic":[38,53,118,163,183],"and":[39,87,157],"depressive":[40,178],"episodes,":[41,179],"usually":[42],"alternated":[43],"periods":[45],"normal":[47],"between":[49],"episodes.":[51],"A":[52,95,120],"episode":[54,97,125],"characterised":[56],"an":[58],"elevated,":[59],"expansive":[60],"or":[61,79,109,140,146,150,155,176],"irritable":[62],"which":[64,171],"can":[65],"be":[66],"accompanied":[67],"high":[70],"self-esteem,":[71],"decreased":[72],"need":[73],"sleep,":[75],"flight":[76],"ideas":[78],"racing":[80],"thoughts,":[81],"increased":[82],"speech,":[83],"distractibility,":[84],"psychomotor":[85,138],"agitation":[86],"excessive":[88],"involvement":[89],"activities":[91],"painful":[93],"consequences.":[94],"hypomanic":[96],"meets":[98],"criteria":[100],"for":[101],"mania":[102],"but":[103,180],"not":[105],"associated":[106],"social":[108],"occupational":[110],"impairment":[111],"as":[112],"case":[115],"episode.":[119,186],"patient":[121],"depressed":[124,128],"has":[126],"together":[130],"possible":[133],"following":[134],"symptoms:":[135],"sleep":[136],"disturbances,":[137],"retardation":[139],"agitation,":[141],"fatigue,":[142],"feelings":[143],"worthlessness":[145],"guilt,":[147],"impaired":[148],"thinking":[149],"concentration,":[151],"change":[152],"appetite":[154],"weight":[156],"suicidal":[158],"thoughts.2,":[159],"3":[160],"With":[161],"its":[162],"episodes":[164],"bipolar":[165],"differs":[167],"from":[168],"(unipolar)":[169],"depression,":[170],"characterized":[173],"more":[177],"never":[181],"(or":[184],"hypomanic)":[185]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}