{"id":"https://openalex.org/W1666501428","doi":"https://doi.org/10.1128/jvi.35.2.519-530.1980","title":"Mutations in Coliphage P1 Affecting Host Cell Lysis","display_name":"Mutations in Coliphage P1 Affecting Host Cell Lysis","publication_year":1980,"publication_date":"1980-08-01","ids":{"openalex":"https://openalex.org/W1666501428","doi":"https://doi.org/10.1128/jvi.35.2.519-530.1980","mag":"1666501428","pmid":"https://pubmed.ncbi.nlm.nih.gov/16789200","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/288837"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.35.2.519-530.1980","doi":"https://doi.org/10.1128/jvi.35.2.519-530.1980","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.35.2.519-530.1980","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/288837","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109933060","display_name":"J T Walker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean Tweedy Walker","raw_affiliation_strings":["Department of Microbiology, University of Iowa, Iowa City, Iowa 52242"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, University of Iowa, Iowa City, Iowa 52242","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035223547","display_name":"Donald H. Walker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald H. Walker","raw_affiliation_strings":["Department of Microbiology, University of Iowa, Iowa City, Iowa 52242"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, University of Iowa, Iowa City, Iowa 52242","institution_ids":["https://openalex.org/I126307644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I126307644"],"apc_list":null,"apc_paid":null,"fwci":0.7957,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.66913809,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"35","issue":"2","first_page":"519","last_page":"530"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacteriophage-p1","display_name":"bacteriophage P1","score":0.9359999895095825},{"id":"https://openalex.org/keywords/host-cell-lysis","display_name":"host cell lysis","score":0.8690000176429749},{"id":"https://openalex.org/keywords/amber-mutations","display_name":"amber mutants","score":0.902999997138977},{"id":"https://openalex.org/keywords/phage-gene-regulation","display_name":"phage gene regulation","score":0.4699999988079071},{"id":"https://openalex.org/keywords/late-gene-expression","display_name":"late gene expression","score":0.75},{"id":"https://openalex.org/keywords/late-proteins","display_name":"late proteins","score":0.47699999809265137}],"concepts":[{"id":"https://openalex.org/C57409179","wikidata":"https://www.wikidata.org/wiki/Q1218293","display_name":"Lysis","level":2,"score":0.9058897495269775},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.8576205968856812},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8384253978729248},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.604823887348175},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.595583975315094},{"id":"https://openalex.org/C2776336130","wikidata":"https://www.wikidata.org/wiki/Q3738783","display_name":"Coliphage","level":5,"score":0.5211731791496277},{"id":"https://openalex.org/C136199206","wikidata":"https://www.wikidata.org/wiki/Q1148110","display_name":"Lysogenic cycle","level":5,"score":0.4585111141204834},{"id":"https://openalex.org/C2776441376","wikidata":"https://www.wikidata.org/wiki/Q165028","display_name":"Bacteriophage","level":4,"score":0.41092756390571594},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3504353165626526},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2133067548274994},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.17592543363571167}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.35.2.519-530.1980","doi":"https://doi.org/10.1128/jvi.35.2.519-530.1980","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.35.2.519-530.1980","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:288837","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/288837","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:16789200","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16789200","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:288837","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/288837","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W184982198","https://openalex.org/W1484440635","https://openalex.org/W1501857461","https://openalex.org/W1535722856","https://openalex.org/W1590399327","https://openalex.org/W1938094451","https://openalex.org/W1943327251","https://openalex.org/W1966360677","https://openalex.org/W1966491084","https://openalex.org/W1970180355","https://openalex.org/W1978662360","https://openalex.org/W1981188561","https://openalex.org/W1981333007","https://openalex.org/W1982677350","https://openalex.org/W1995448634","https://openalex.org/W2002411289","https://openalex.org/W2011399970","https://openalex.org/W2018633073","https://openalex.org/W2022575029","https://openalex.org/W2030205636","https://openalex.org/W2032402228","https://openalex.org/W2063179539","https://openalex.org/W2072175205","https://openalex.org/W2074822534","https://openalex.org/W2086392820","https://openalex.org/W2088950300","https://openalex.org/W2094292178","https://openalex.org/W2094332622","https://openalex.org/W2163716963","https://openalex.org/W2886774383"],"related_works":["https://openalex.org/W2059267375","https://openalex.org/W2086110847","https://openalex.org/W2015748935","https://openalex.org/W2015237046","https://openalex.org/W2058406595","https://openalex.org/W1978662360","https://openalex.org/W2029243882","https://openalex.org/W2009345668","https://openalex.org/W1791876011","https://openalex.org/W1485557899"],"abstract_inverted_index":{"A":[0],"total":[1],"of":[2,6,13,71,86,109,184,211],"103":[3],"amber":[4,34,57,135],"mutants":[5,58,73,95,112,194],"coliphage":[7],"P1":[8],"were":[9,59,81,121,139,149,169,179],"tested":[10],"for":[11,208,215],"lysis":[12,21,25,46,54,102,116],"nonpermissive":[14],"cells.":[15,89,187],"Of":[16],"these,":[17],"83":[18],"caused":[19,44],"cell":[20,63,154],"at":[22],"the":[23,39,100,107,126,144,191],"normal":[24,101],"time":[26],"and":[27,47,78,175,199],"have":[28,49],"defects":[29],"in":[30,38,52,83,114,125,143,160,163,181],"particle":[31],"morphogenesis.":[32],"Five":[33],"mutants,":[35,136],"with":[36,69],"mutations":[37,120,138],"same":[40,127,145],"gene":[41,128,130,146,161,192,204,213],"(gene":[42,147],"2),":[43],"premature":[45],"may":[48,206],"a":[50,53,115,209],"defect":[51,108],"regulator.":[55],"Fifteen":[56],"unable":[60,151],"to":[61,123,141,152],"cause":[62,153],"lysis.":[64,155],"Artificially":[65],"lysed":[66,173],"cells":[67],"infected":[68,88,186],"five":[70,111,119],"these":[72,94,110],"produced":[74,170],"viable":[75,166],"phage":[76,79,91,167,177],"particles,":[77],"particles":[80,168,178],"seen":[82,180],"thin":[84,182],"sections":[85,183],"unlysed,":[87,185],"However,":[90],"production":[92],"by":[93],"was":[96],"not":[97],"continued":[98],"after":[99],"time.":[103],"We":[104,188],"conclude":[105,189],"that":[106,164,190,203],"is":[113,201],"function.":[117],"The":[118,132],"found":[122,140],"be":[124,142],"(designated":[129],"17).":[131],"remaining":[133],"10":[134,193,205],"whose":[137],"10),":[148],"also":[150],"They":[156],"differed":[157],"from":[158,171],"those":[159],"17":[162],"no":[165,176],"artificially":[172],"cells,":[174],"cannot":[195],"synthesize":[196],"late":[197,212],"proteins,":[198],"it":[200],"possible":[202],"code":[207],"regulator":[210],"expression":[214],"P1.":[216]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}
