{"id":"https://openalex.org/W1663165860","doi":"https://doi.org/10.3978/j.issn.1000-9604.2014.09.03","title":"WWOX suppresses KLF5 expression and breast cancer cell growth.","display_name":"WWOX suppresses KLF5 expression and breast cancer cell growth.","publication_year":2014,"publication_date":"2014-10-01","ids":{"openalex":"https://openalex.org/W1663165860","doi":"https://doi.org/10.3978/j.issn.1000-9604.2014.09.03","mag":"1663165860","pmid":"https://pubmed.ncbi.nlm.nih.gov/25400415","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4220264"},"language":"en","primary_location":{"id":"pmid:25400415","doi":"https://doi.org/10.3978/j.issn.1000-9604.2014.09.03","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25400415","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese journal of cancer research = Chung-kuo yen cheng yen chiu","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4220264/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Fei Ge","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Fei Ge","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100734872","display_name":"Wenlin Chen","orcid":"https://orcid.org/0000-0001-8986-4064","observed_orcids":["https://orcid.org/0000-0001-8986-4064"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Wenlin Chen","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043486034","display_name":"Runxiang Yang","orcid":"https://orcid.org/0000-0002-9974-248X","observed_orcids":["https://orcid.org/0000-0002-9974-248X"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Runxiang Yang","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085137414","display_name":"Zhongmei Zhou","orcid":"https://orcid.org/0000-0001-6392-7936","observed_orcids":["https://orcid.org/0000-0001-6392-7936"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Zhongmei Zhou","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030428760","display_name":"Nan\u2010Shan Chang","orcid":"https://orcid.org/0000-0002-6889-8756","observed_orcids":["https://orcid.org/0000-0002-6889-8756"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Nanshan Chang","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047917101","display_name":"Ceshi Chen","orcid":"https://orcid.org/0000-0001-6398-3516","observed_orcids":["https://orcid.org/0000-0001-6398-3516"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Ceshi Chen","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001662172","display_name":"Tianning Zou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Tianning Zou","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100346447","display_name":"Rong Liu","orcid":"https://orcid.org/0000-0001-5170-6474","observed_orcids":["https://orcid.org/0000-0001-5170-6474"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Rong Liu","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026320292","display_name":"Jing Ying Tan","orcid":"https://orcid.org/0000-0002-4605-4624","observed_orcids":["https://orcid.org/0000-0002-4605-4624"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Jing Tan","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103199355","display_name":"Guosheng Ren","orcid":"https://orcid.org/0009-0004-0158-421X","observed_orcids":["https://orcid.org/0009-0004-0158-421X","https://orcid.org/0000-0002-6416-8967"]},"institutions":[{"id":"https://openalex.org/I18489884","display_name":"Kunming Institute of Zoology","ror":"https://ror.org/03m0vk445","country_code":"CN","type":"facility","lineage":["https://openalex.org/I18489884","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Guosheng Ren","raw_affiliation_strings":["1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Endocrine Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China ; 2 Department of Breast Surgery, 3 Second Department of Internal Medicine of Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Kunming 650118, China ; 4 Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China ; 5 Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, China","institution_ids":["https://openalex.org/I18489884","https://openalex.org/I19820366","https://openalex.org/I26080491","https://openalex.org/I87780372","https://openalex.org/I91807558"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2082,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.44070798,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"26","issue":"5","first_page":"511","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13426","display_name":"Kruppel-like factors research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13426","display_name":"Kruppel-like factors research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13437","display_name":"Mechanisms of cancer metastasis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wwox","display_name":"WWOX","score":1.0},{"id":"https://openalex.org/keywords/klf5","display_name":"KLF5","score":0.9459999799728394},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8149999976158142},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.8610000014305115},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.7580000162124634},{"id":"https://openalex.org/keywords/ww-domain","display_name":"WW domain","score":0.8270000219345093},{"id":"https://openalex.org/keywords/py-motif","display_name":"PY motif","score":0.8730000257492065},{"id":"https://openalex.org/keywords/oncogenic-transcription-factor","display_name":"oncogenic transcription factor","score":0.800000011920929},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.8199999928474426},{"id":"https://openalex.org/keywords/bladder-cancer","display_name":"bladder cancer","score":0.8809999823570251},{"id":"https://openalex.org/keywords/basal-like-breast-cancer","display_name":"basal-like breast cancer","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C2780770488","wikidata":"https://www.wikidata.org/wiki/Q18040542","display_name":"WWOX","level":4,"score":0.9918649196624756},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7144366502761841},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6810917854309082},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.5857210159301758},{"id":"https://openalex.org/C60449816","wikidata":"https://www.wikidata.org/wiki/Q5113903","display_name":"Chromosomal fragile site","level":4,"score":0.5379076600074768},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5348035097122192},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4891507923603058},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.42038556933403015},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39958763122558594},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3126431703567505},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26129135489463806},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17389467358589172},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11261898279190063},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmid:25400415","doi":"https://doi.org/10.3978/j.issn.1000-9604.2014.09.03","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25400415","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese journal of cancer research = Chung-kuo yen cheng yen chiu","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4220264","doi":"https://doi.org/10.3978/j.issn.1000-9604.2014.09.03","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4220264/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chin J Cancer Res","raw_type":"Text"},{"id":"mag:1663165860","doi":"https://doi.org/10.3978/j.issn.1000-9604.2014.09.03","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25400415","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:3141090432","doi":null,"is_oa":false,"landing_page_url":"http://www.cqvip.com/QK/85190X/201405/663062781.html","pdf_url":null,"source":{"id":"https://openalex.org/S26659863","display_name":"Chinese Journal of Cancer Research","issn_l":"1000-9604","issn":["1000-9604","1993-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","oarl","poland-100"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u4e2d\u56fd\u764c\u75c7\u7814\u7a76\uff1a\u82f1\u6587\u7248","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4220264","doi":"https://doi.org/10.3978/j.issn.1000-9604.2014.09.03","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4220264/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chin J Cancer Res","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1593442063","https://openalex.org/W1965881928","https://openalex.org/W2038780517","https://openalex.org/W2039633981","https://openalex.org/W2040511060","https://openalex.org/W2042693266","https://openalex.org/W2044702943","https://openalex.org/W2052550247","https://openalex.org/W2053232173","https://openalex.org/W2064365978","https://openalex.org/W2068626866","https://openalex.org/W2070313422","https://openalex.org/W2073759231","https://openalex.org/W2083436757","https://openalex.org/W2085488377","https://openalex.org/W2087512862","https://openalex.org/W2092629648","https://openalex.org/W2093818952","https://openalex.org/W2108925373","https://openalex.org/W2117344319","https://openalex.org/W2123040840","https://openalex.org/W2131740501","https://openalex.org/W2132523464","https://openalex.org/W2132893003","https://openalex.org/W2136683006","https://openalex.org/W2138954352","https://openalex.org/W2144663664","https://openalex.org/W2150185773","https://openalex.org/W2157840751","https://openalex.org/W2166732297","https://openalex.org/W2170602872"],"related_works":["https://openalex.org/W2886191476","https://openalex.org/W2323245296","https://openalex.org/W2054708975","https://openalex.org/W2318753556","https://openalex.org/W2025093834","https://openalex.org/W1881009506","https://openalex.org/W2314005406","https://openalex.org/W2144663664","https://openalex.org/W2117344319","https://openalex.org/W3158071307"],"abstract_inverted_index":{"The":[0],"WW":[1,100],"domain-containing":[2],"oxidoreductase":[3],"(WWOX)":[4],"is":[5,20],"a":[6,10,27,120],"tumor":[7],"suppressor":[8],"in":[9,50,80,119],"variety":[11],"of":[12,47,68,112,122,143],"cancers,":[13],"including":[14],"breast":[15,34,84,123],"cancer.":[16],"Reduced":[17],"WWOX":[18,39,65,92,113,132],"expression":[19,67,111,118,142],"associated":[21],"with":[22,95,116],"the":[23,44,60,98,103,110,141],"basal-like":[24],"subtype":[25],"and":[26,75,83,102],"relatively":[28],"poor":[29],"disease-free":[30],"survival":[31],"rate":[32],"among":[33],"cancer":[35,77,85,124,135],"patients.":[36],"Though":[37],"several":[38],"partners":[40],"have":[41,52],"been":[42,54],"identified,":[43],"functional":[45],"mechanisms":[46],"WWOX's":[48],"role":[49],"cancers":[51],"not":[53],"fully":[55],"addressed":[56],"to":[57],"date.":[58],"In":[59],"current":[61],"study,":[62],"we":[63,89,108,129],"found":[64,109],"suppresses":[66,76],"KLF5-an":[69],"oncogenic":[70],"transcription":[71],"factor-at":[72],"protein":[73],"level,":[74],"cell":[78,86,125,136],"proliferation":[79,137],"both":[81],"bladder":[82],"lines.":[87,126],"Furthermore,":[88],"demonstrated":[90],"that":[91,131],"physically":[93],"interacts":[94],"KLF5":[96,117],"via":[97],"former's":[99],"domains":[101],"latter's":[104],"PY":[105],"motifs.":[106],"Interestingly,":[107],"negatively":[114],"correlates":[115],"panel":[121],"Taken":[127],"together,":[128],"conjecture":[130],"may":[133],"suppress":[134],"partially":[138],"by":[139],"reducing":[140],"KLF5.":[144]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
