{"id":"https://openalex.org/W1662893264","doi":"https://doi.org/10.1128/jcm.11.6.562-568.1980","title":"Direct agglutination test for diagnosis of Toxoplasma infection: method for increasing sensitivity and specificity","display_name":"Direct agglutination test for diagnosis of Toxoplasma infection: method for increasing sensitivity and specificity","publication_year":1980,"publication_date":"1980-06-01","ids":{"openalex":"https://openalex.org/W1662893264","doi":"https://doi.org/10.1128/jcm.11.6.562-568.1980","mag":"1662893264","pmid":"https://pubmed.ncbi.nlm.nih.gov/7000807","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/273461"},"language":"en","primary_location":{"id":"doi:10.1128/jcm.11.6.562-568.1980","doi":"https://doi.org/10.1128/jcm.11.6.562-568.1980","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jcm.11.6.562-568.1980","pdf_url":null,"source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/273461","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110415964","display_name":"Georges Desmonts","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Desmonts","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109840575","display_name":"Jack S. Remington","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J S Remington","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.5483,"has_fulltext":false,"cited_by_count":589,"citation_normalized_percentile":{"value":0.95953554,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"11","issue":"6","first_page":"562","last_page":"568"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11155","display_name":"Toxoplasma gondii Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11155","display_name":"Toxoplasma gondii Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11154","display_name":"Parasitic infections in humans and animals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/toxoplasma-gondii","display_name":"Toxoplasma gondii","score":0.9490000009536743},{"id":"https://openalex.org/keywords/toxoplasmosis","display_name":"toxoplasmosis","score":0.9570000171661377},{"id":"https://openalex.org/keywords/direct-agglutination-test","display_name":"direct agglutination test","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sabin-feldman-dye-test","display_name":"Sabin-Feldman dye test","score":0.9409999847412109},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.8100000023841858},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.8320000171661377},{"id":"https://openalex.org/keywords/seroconversion","display_name":"seroconversion","score":0.6019999980926514},{"id":"https://openalex.org/keywords/chronic-infection","display_name":"chronic infection","score":0.8320000171661377},{"id":"https://openalex.org/keywords/acute-infection","display_name":"acute infection","score":0.9079999923706055},{"id":"https://openalex.org/keywords/screening-test","display_name":"screening test","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.8420902490615845},{"id":"https://openalex.org/C73878171","wikidata":"https://www.wikidata.org/wiki/Q5280305","display_name":"Direct agglutination test","level":4,"score":0.7349997758865356},{"id":"https://openalex.org/C37977956","wikidata":"https://www.wikidata.org/wiki/Q1806946","display_name":"Latex fixation test","level":3,"score":0.7181081771850586},{"id":"https://openalex.org/C2778128430","wikidata":"https://www.wikidata.org/wiki/Q131003","display_name":"Toxoplasma gondii","level":3,"score":0.6537868976593018},{"id":"https://openalex.org/C2909814700","wikidata":"https://www.wikidata.org/wiki/Q18207010","display_name":"False Negative Reactions","level":2,"score":0.5529414415359497},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5218300223350525},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.505894124507904},{"id":"https://openalex.org/C2778062946","wikidata":"https://www.wikidata.org/wiki/Q154878","display_name":"Toxoplasmosis","level":2,"score":0.4796900451183319},{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.43990617990493774},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.4324694573879242},{"id":"https://openalex.org/C3020067899","wikidata":"https://www.wikidata.org/wiki/Q1163564","display_name":"Screening test","level":2,"score":0.4226621985435486},{"id":"https://openalex.org/C143508840","wikidata":"https://www.wikidata.org/wiki/Q393294","display_name":"Agglutination (biology)","level":3,"score":0.41465532779693604},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.4080742597579956},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3653014302253723},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2875581681728363},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2784918546676636},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23051130771636963},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.09620928764343262},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000372","descriptor_name":"Agglutination Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007075","descriptor_name":"Immunoglobulin M","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014123","descriptor_name":"Toxoplasmosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/jcm.11.6.562-568.1980","doi":"https://doi.org/10.1128/jcm.11.6.562-568.1980","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jcm.11.6.562-568.1980","pdf_url":null,"source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1313506","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/273461","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:7000807","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7000807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical microbiology","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:273461","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC273461/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Microbiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1313506","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/273461","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W23417003","https://openalex.org/W2003162520","https://openalex.org/W2008747704","https://openalex.org/W2024251697","https://openalex.org/W2161150936","https://openalex.org/W2406649387","https://openalex.org/W2411933373","https://openalex.org/W2413074028","https://openalex.org/W2414862287","https://openalex.org/W2417850926","https://openalex.org/W2421873056"],"related_works":["https://openalex.org/W1974554373","https://openalex.org/W2139308345","https://openalex.org/W1994295509","https://openalex.org/W1994094125","https://openalex.org/W1979769471","https://openalex.org/W2411586285","https://openalex.org/W2419951604","https://openalex.org/W23417003","https://openalex.org/W2351865968","https://openalex.org/W2276300851"],"abstract_inverted_index":{"A":[0],"method":[1],"that":[2],"increases":[3],"the":[4,9,25,48,52,65,72,81,90,100,121],"sensitivity":[5],"and":[6,30,112,117,128],"specificity":[7],"of":[8,16,50,123,131],"direct":[10],"agglutination":[11],"(AG)":[12],"test":[13,28,32,58,74,92,102,111],"for":[14,106,120,129],"diagnosis":[15],"Toxoplasma":[17],"gondii":[18],"infection":[19],"is":[20],"described.":[21],"Qualitative":[22],"results":[23],"in":[24,34,39,84],"Sabin-Feldman":[26],"dye":[27],"(DT)":[29],"AG":[31,57,73,91,101],"were":[33],"excellent":[35],"agreement":[36],"(98%).":[37],"Differences":[38],"titers":[40],"between":[41],"these":[42],"two":[43],"tests":[44],"often":[45,62,78],"related":[46],"to":[47],"length":[49],"time":[51],"individual":[53],"was":[54,60,76],"infected.":[55],"The":[56],"titer":[59,67,75,83],"most":[61,77],"lower":[63],"than":[64,80],"DT":[66,82],"during":[68,126],"acute":[69],"(recent)":[70],"infection;":[71],"higher":[79],"older":[85],"or":[86],"chronic":[87],"infection.":[88],"If":[89],"antigen":[93],"described":[94],"here":[95],"can":[96],"be":[97,104],"made":[98],"available,":[99],"would":[103,113],"ideal":[105],"use":[107],"as":[108],"a":[109,115],"screening":[110],"provide":[114],"simple":[116],"inexpensive":[118],"means":[119],"surveillance":[122],"seronegative":[124],"women":[125],"pregnancy":[127],"detection":[130],"seroconversions.":[132]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":19},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":27},{"year":2016,"cited_by_count":26},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":27},{"year":2013,"cited_by_count":27},{"year":2012,"cited_by_count":22}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}