{"id":"https://openalex.org/W1661375447","doi":"https://doi.org/10.3109/13685538.2015.1032925","title":"Effects of long-term oral testosterone undecanoate therapy on urinary symptoms: data from a 1-year, placebo-controlled, dose-ranging trial in aging men with symptomatic hypogonadism","display_name":"Effects of long-term oral testosterone undecanoate therapy on urinary symptoms: data from a 1-year, placebo-controlled, dose-ranging trial in aging men with symptomatic hypogonadism","publication_year":2015,"publication_date":"2015-06-01","ids":{"openalex":"https://openalex.org/W1661375447","doi":"https://doi.org/10.3109/13685538.2015.1032925","mag":"1661375447","pmid":"https://pubmed.ncbi.nlm.nih.gov/26030346"},"language":"en","primary_location":{"id":"doi:10.3109/13685538.2015.1032925","doi":"https://doi.org/10.3109/13685538.2015.1032925","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685538.2015.1032925","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2015.1032925?needAccess=true","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2015.1032925?needAccess=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111904548","display_name":"ERIC J. H. MEULEMAN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Eric J. H. Meuleman","raw_affiliation_strings":["a Department of Urology , VU University Medical Center , Amsterdam , The Netherlands ","Department of Urology; VU University Medical Center; Amsterdam The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Department of Urology , VU University Medical Center , Amsterdam , The Netherlands ","institution_ids":["https://openalex.org/I911458345"]},{"raw_affiliation_string":"Department of Urology; VU University Medical Center; Amsterdam The Netherlands","institution_ids":["https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108591112","display_name":"Jean\u2010Jacques Legros","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157674565","display_name":"University of Li\u00e8ge","ror":"https://ror.org/00afp2z80","country_code":"BE","type":"education","lineage":["https://openalex.org/I157674565"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jean-Jacques Legros","raw_affiliation_strings":["b Department of Endocrinology , University of Liege , Liege , Belgium ","Department of Endocrinology, University of Li\u00e8ge, Li\u00e8ge, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"b Department of Endocrinology , University of Liege , Liege , Belgium ","institution_ids":["https://openalex.org/I157674565"]},{"raw_affiliation_string":"Department of Endocrinology, University of Li\u00e8ge, Li\u00e8ge, Belgium","institution_ids":["https://openalex.org/I157674565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105003642","display_name":"Pierre Marc Bouloux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pierre M. G. Bouloux","raw_affiliation_strings":["c Centre for Neuroendocrinology, Royal Free and University College School of Medicine , London , UK ","Centre for Neuroendocrinology, Royal Free and University College School of Medicine, London, UK,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"c Centre for Neuroendocrinology, Royal Free and University College School of Medicine , London , UK ","institution_ids":["https://openalex.org/I2801138448","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Neuroendocrinology, Royal Free and University College School of Medicine, London, UK,","institution_ids":["https://openalex.org/I2801138448","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021709407","display_name":"Amy O. Johnson\u2010Levonas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy O. Johnson-Levonas","raw_affiliation_strings":["d Merck & Co., Inc., Whitehouse Station , New Jersey , NJ , USA , and","Merck & Co., Inc., Whitehouse Station, New Jersey, NJ, USA, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"d Merck & Co., Inc., Whitehouse Station , New Jersey , NJ , USA , and","institution_ids":["https://openalex.org/I1285764155"]},{"raw_affiliation_string":"Merck & Co., Inc., Whitehouse Station, New Jersey, NJ, USA, and","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007662234","display_name":"Marion J. G. H. Kaspers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162999","display_name":"MSD (Netherlands)","ror":"https://ror.org/05y28vr04","country_code":"NL","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210162999"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marion J. G. H. Kaspers","raw_affiliation_strings":["e MSD Oss , Oss , The Netherlands","MSD Oss, Oss, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"e MSD Oss , Oss , The Netherlands","institution_ids":["https://openalex.org/I4210162999"]},{"raw_affiliation_string":"MSD Oss, Oss, The Netherlands","institution_ids":["https://openalex.org/I4210162999"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110245465","display_name":"Jolanda M. H. Elbers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162999","display_name":"MSD (Netherlands)","ror":"https://ror.org/05y28vr04","country_code":"NL","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210162999"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jolanda M. H. Elbers","raw_affiliation_strings":["e MSD Oss , Oss , The Netherlands","MSD Oss, Oss, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"e MSD Oss , Oss , The Netherlands","institution_ids":["https://openalex.org/I4210162999"]},{"raw_affiliation_string":"MSD Oss, Oss, The Netherlands","institution_ids":["https://openalex.org/I4210162999"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022009675","display_name":"T. B. Paul Geurts","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162999","display_name":"MSD (Netherlands)","ror":"https://ror.org/05y28vr04","country_code":"NL","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210162999"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"T. B. Paul Geurts","raw_affiliation_strings":["e MSD Oss , Oss , The Netherlands","MSD Oss, Oss, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"e MSD Oss , Oss , The Netherlands","institution_ids":["https://openalex.org/I4210162999"]},{"raw_affiliation_string":"MSD Oss, Oss, The Netherlands","institution_ids":["https://openalex.org/I4210162999"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110287794","display_name":"Alan G. Meehan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan G. Meehan","raw_affiliation_strings":["d Merck & Co., Inc., Whitehouse Station , New Jersey , NJ , USA , and","Merck & Co., Inc., Whitehouse Station, New Jersey, NJ, USA, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"d Merck & Co., Inc., Whitehouse Station , New Jersey , NJ , USA , and","institution_ids":["https://openalex.org/I1285764155"]},{"raw_affiliation_string":"Merck & Co., Inc., Whitehouse Station, New Jersey, NJ, USA, and","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"last","author":{"id":null,"display_name":"for the Study 43203 Investigators","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"for the Study 43203 Investigators","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5111904548"],"corresponding_institution_ids":["https://openalex.org/I911458345"],"apc_list":{"value":2085,"currency":"GBP","value_usd":2557},"apc_paid":null,"fwci":3.5019,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.92801178,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"18","issue":"3","first_page":"157","last_page":"163"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testosterone-undecanoate","display_name":"testosterone undecanoate","score":0.9300000071525574},{"id":"https://openalex.org/keywords/testosterone-deficiency","display_name":"androgen deficiency","score":0.7110000252723694},{"id":"https://openalex.org/keywords/hypogonadism","display_name":"hypogonadism","score":0.847000002861023},{"id":"https://openalex.org/keywords/older-men","display_name":"older men","score":0.8880000114440918},{"id":"https://openalex.org/keywords/urinary-symptoms","display_name":"urinary symptoms","score":0.9039999842643738},{"id":"https://openalex.org/keywords/international-prostate-symptom-score","display_name":"International Prostate Symptom Score","score":0.9480000138282776},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8560000061988831},{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.7960000038146973},{"id":"https://openalex.org/keywords/prostate-volume","display_name":"prostate volume","score":0.7639999985694885},{"id":"https://openalex.org/keywords/dose-ranging-study","display_name":"dose-ranging","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.92670738697052},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.6932154297828674},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6890103816986084},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.608237087726593},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5696410536766052},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4717867076396942},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007006","descriptor_name":"Hypogonadism","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D007006","descriptor_name":"Hypogonadism","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011470","descriptor_name":"Prostatic Hyperplasia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D059411","descriptor_name":"Lower Urinary Tract Symptoms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D059411","descriptor_name":"Lower Urinary Tract Symptoms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3109/13685538.2015.1032925","doi":"https://doi.org/10.3109/13685538.2015.1032925","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685538.2015.1032925","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2015.1032925?needAccess=true","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},{"id":"pmid:26030346","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26030346","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The aging male : the official journal of the International Society for the Study of the Aging Male","raw_type":"Journal Article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire/ae46b85f-cdfc-4b05-bf4d-a54e9d10f609","doi":null,"is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/ae46b85f-cdfc-4b05-bf4d-a54e9d10f609","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Meuleman, E J H, Legros, J J, Bouloux, P M G, Johnson-Levonas, A O, Kaspers, M J G H, Elbers, J M H, Geurts, T B P & Meehan, A G 2015, 'Effects of long-term oral testosterone undecanoate therapy on urinary symptoms: data from a 1-year, placebo-controlled, dose-ranging trial in aging men with symptomatic hypogonadism', The Aging Male, vol. 18, no. 3, pp. 157-163. https://doi.org/10.3109/13685538.2015.1032925","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:archive.ugent.be:8022719","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1854/LU-8022719","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1368-5538","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:vumc:oai:pure.atira.dk:publications/58d398b9-ff3b-4590-888f-8229df9d6f37","doi":null,"is_oa":false,"landing_page_url":"https://research.vumc.nl/en/publications/58d398b9-ff3b-4590-888f-8229df9d6f37","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Aging Male, 18(3), 157 - 163. Taylor and Francis Ltd.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3109/13685538.2015.1032925","doi":"https://doi.org/10.3109/13685538.2015.1032925","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685538.2015.1032925","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2015.1032925?needAccess=true","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1661375447.pdf","grobid_xml":"https://content.openalex.org/works/W1661375447.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1571884047","https://openalex.org/W2041933045","https://openalex.org/W2057665264","https://openalex.org/W2084775753","https://openalex.org/W2096714067","https://openalex.org/W2098247759","https://openalex.org/W2113645951","https://openalex.org/W2121759271","https://openalex.org/W2155965183","https://openalex.org/W2160753800","https://openalex.org/W2577042876","https://openalex.org/W2993539218"],"related_works":["https://openalex.org/W1963652218","https://openalex.org/W2737515883","https://openalex.org/W3138858022","https://openalex.org/W4306933363","https://openalex.org/W3040510171","https://openalex.org/W2096714067","https://openalex.org/W4372351216","https://openalex.org/W2168247237","https://openalex.org/W2583688168","https://openalex.org/W2084145186"],"abstract_inverted_index":{"BACKGROUND:":[0],"There":[1],"has":[2],"been":[3],"a":[4,53,113,125,139,174],"longstanding":[5],"question":[6],"as":[7],"to":[8,112],"whether":[9],"testosterone":[10,28,49],"therapy":[11,31,150,172],"could":[12],"precipitate":[13],"or":[14,62,69,99,144],"worsen":[15],"urinary":[16,33,97],"symptoms":[17,34,98],"in":[18,35,52,91,95,120,128,166],"aging":[19],"men.":[20,38,169],"We":[21],"investigated":[22],"the":[23,134],"effects":[24,154],"of":[25,42,84,101,133,176],"1-year":[26],"oral":[27,63,80,107,148],"undecanoate":[29],"(TU)":[30],"on":[32,142,155],"aging,":[36,167],"hypogonadal":[37,168],"METHODS:":[39],"A":[40],"total":[41,122,157],"322":[43],"men":[44],"\u226550":[45],"years":[46],"with":[47,76,79,106],"symptomatic":[48],"deficiency":[50],"participated":[51],"1-year,":[54],"randomized,":[55],"multicenter,":[56],"double-blind":[57],"trial.":[58],"Patients":[59],"received":[60],"placebo":[61],"TU":[64,81,108,135,149,171],"80":[65,85],"mg/day,":[66,68],"160":[67,88],"240":[70,109,177],"mg/day.":[71],"RESULTS":[72],"AND":[73],"LIMITATIONS:":[74],"Compared":[75],"placebo,":[77],"treatment":[78],"at":[82,173],"doses":[83,136],"mg/day":[86,89,110,178],"and":[87,124,159,164],"resulted":[90],"no":[92,152],"significant":[93,126,140],"change":[94,162],"IPSS":[96,121,129,156,182],"quality":[100],"life":[102],"(QoL)":[103],"scores.":[104],"Treatment":[105],"led":[111],"statistically":[114],"significant,":[115],"but":[116],"clinically":[117],"insignificant,":[118],"improvement":[119,127],"score":[123,158],"QoL":[130,183],"score.":[131,184],"None":[132],"tested":[137],"had":[138,151],"effect":[141],"PSA":[143,165],"PV.":[145],"CONCLUSIONS:":[146],"Long-term":[147],"deleterious":[153],"did":[160],"not":[161],"PV":[163],"Oral":[170],"dose":[175],"may":[179],"even":[180],"improve":[181]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
