{"id":"https://openalex.org/W165264381","doi":null,"title":"Effect of smoking and smoking cessation on bone mass, bone remodeling, vitamin D, PTH and sex hormones.","display_name":"Effect of smoking and smoking cessation on bone mass, bone remodeling, vitamin D, PTH and sex hormones.","publication_year":2006,"publication_date":"2006-07-01","ids":{"openalex":"https://openalex.org/W165264381","mag":"165264381","pmid":"https://pubmed.ncbi.nlm.nih.gov/17142943"},"language":"en","primary_location":{"id":"pmid:17142943","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17142943","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047601232","display_name":"August Superv\u00eda","orcid":"https://orcid.org/0000-0003-3256-7469","observed_orcids":["https://orcid.org/0000-0003-3256-7469"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Superv\u00eda","raw_affiliation_strings":["Department of Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069502074","display_name":"Xavier Nogu\u00e9s","orcid":"https://orcid.org/0000-0002-5537-1859","observed_orcids":["https://orcid.org/0000-0002-5537-1859"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"X Nogu\u00e9s","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085736332","display_name":"Anna Enjuanes","orcid":"https://orcid.org/0000-0002-4679-6687","observed_orcids":["https://orcid.org/0000-0002-4679-6687"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Enjuanes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031851415","display_name":"Joan Vila","orcid":"https://orcid.org/0000-0003-1082-6861","observed_orcids":["https://orcid.org/0000-0003-1082-6861"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Vila","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068760134","display_name":"Leonardo Mellibovsky","orcid":"https://orcid.org/0009-0001-7921-8840","observed_orcids":["https://orcid.org/0009-0001-7921-8840"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Mellibovsky","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112240477","display_name":"Sergi Serrano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Serrano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019055363","display_name":"Jaume Aubia","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Aub\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5052312125","display_name":"Adolfo D\u00edez\u2010P\u00e9rez","orcid":"https://orcid.org/0000-0001-8162-0209","observed_orcids":["https://orcid.org/0000-0001-8162-0209"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A D\u00edez-P\u00e9rez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4381,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.87731799,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"6","issue":"3","first_page":"234","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.4318999946117401,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.017999999225139618,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.9850000143051147},{"id":"https://openalex.org/keywords/smoking-cessation","display_name":"smoking cessation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.9210000038146973},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.9739999771118164},{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.6779999732971191},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.9670000076293945},{"id":"https://openalex.org/keywords/sex-hormones","display_name":"sex hormones","score":0.9950000047683716},{"id":"https://openalex.org/keywords/estrone","display_name":"estrone","score":0.9380000233650208},{"id":"https://openalex.org/keywords/25-hydroxyvitamin-d","display_name":"25-hydroxyvitamin D","score":0.9089999794960022},{"id":"https://openalex.org/keywords/sex-hormone-binding-globulin","display_name":"sex hormone-binding globulin","score":0.925000011920929},{"id":"https://openalex.org/keywords/urinary-ntx","display_name":"urinary NTX","score":0.8090000152587891},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.9860000014305115},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.859000027179718}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8370883464813232},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7615550756454468},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.7419501543045044},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6950502991676331},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.6870298385620117},{"id":"https://openalex.org/C673006","wikidata":"https://www.wikidata.org/wiki/Q4941581","display_name":"Bone resorption","level":2,"score":0.5788885354995728},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.5638390779495239},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5435710549354553},{"id":"https://openalex.org/C2778656385","wikidata":"https://www.wikidata.org/wiki/Q414986","display_name":"Estrone","level":3,"score":0.5401431918144226},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.1716834306716919}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012738","descriptor_name":"Sex Hormone-Binding Globulin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012739","descriptor_name":"Gonadal Steroid Hormones","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016540","descriptor_name":"Smoking Cessation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D024042","descriptor_name":"Collagen Type I","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:17142943","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17142943","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},{"id":"mag:165264381","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17142943","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W211800860","https://openalex.org/W1937064631","https://openalex.org/W1970150199","https://openalex.org/W1978293259","https://openalex.org/W1979851608","https://openalex.org/W1995275528","https://openalex.org/W1996007424","https://openalex.org/W1996163526","https://openalex.org/W2003904705","https://openalex.org/W2005569468","https://openalex.org/W2007125717","https://openalex.org/W2025447496","https://openalex.org/W2028831724","https://openalex.org/W2030140979","https://openalex.org/W2032621659","https://openalex.org/W2032889276","https://openalex.org/W2034227510","https://openalex.org/W2037186387","https://openalex.org/W2037367381","https://openalex.org/W2038073075","https://openalex.org/W2041710987","https://openalex.org/W2051734544","https://openalex.org/W2056460705","https://openalex.org/W2072812147","https://openalex.org/W2075245868","https://openalex.org/W2077817309","https://openalex.org/W2078842817","https://openalex.org/W2079121449","https://openalex.org/W2084377642","https://openalex.org/W2087593575","https://openalex.org/W2095030054","https://openalex.org/W2101552071","https://openalex.org/W2103168073","https://openalex.org/W2113786340","https://openalex.org/W2115000106","https://openalex.org/W2116432257","https://openalex.org/W2160716852","https://openalex.org/W2169664261","https://openalex.org/W2286876010","https://openalex.org/W2302060032","https://openalex.org/W2328266843","https://openalex.org/W2410561535","https://openalex.org/W2418185885","https://openalex.org/W2470898013"],"related_works":["https://openalex.org/W7208608082","https://openalex.org/W2032621659","https://openalex.org/W2055421159","https://openalex.org/W2072812147","https://openalex.org/W2101552071","https://openalex.org/W2018204172","https://openalex.org/W2958973184","https://openalex.org/W3092041180","https://openalex.org/W1499693260","https://openalex.org/W2079121449"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"assess":[2],"the":[3,188],"effect":[4],"of":[5,52,152],"smoking":[6,8,55,147],"and":[7,18,48,89,134,155,163,171],"cessation":[9],"on":[10,187],"bone":[11,13,169,173],"density,":[12],"remodeling":[14],"markers,":[15],"sex":[16,179],"hormones,":[17],"vitamin":[19,189],"D-PTH":[20,190],"axis":[21],"in":[22,108,111,120,161,178],"healthy":[23,32],"young":[24],"subjects.":[25],"MATERIALS":[26],"AND":[27],"METHODS:":[28],"We":[29],"studied":[30],"74":[31],"people":[33],"(31":[34],"men,":[35],"43":[36],"women;":[37],"mean":[38],"age":[39,133],"32.2":[40],"(7)":[41],"years)":[42],"divided":[43],"into":[44],"52":[45],"never":[46,64,112,144],"smokers":[47,61,65,109,121,138],"22":[49],"smokers,":[50,113],"15":[51],"which":[53],"stopped":[54],"for":[56],"one":[57],"month.":[58],"RESULTS:":[59],"Male":[60],"compared":[62],"with":[63],"showed":[66],"lower":[67,90,119],"BMD":[68,104],"(0.971":[69],"(0.11)":[70],"g/cm(2)":[71],"vs.":[72,84,97,125],"1.069":[73],"(0.09)":[74],"g/cm(2),":[75],"P=0.042);":[76],"higher":[77,140],"plasma":[78,157],"estrone":[79],"levels":[80,93,117,142,158],"(32.37":[81],"(10.13)":[82],"pg/mL":[83,96],"20.91":[85],"(5.46)":[86],"pg/mL,":[87,100],"P=0.001);":[88],"serum":[91],"iPTH":[92],"(16.2":[94],"(3.5)":[95],"28.8":[98],"(2.0)":[99],"P=0.008).":[101],"In":[102],"women,":[103,164],"values":[105],"were":[106,118,159],"similar":[107],"than":[110,143],"but":[114,182],"25-hydroxyvitamin":[115,153],"D":[116,154],"(31.9":[122],"(15.1)":[123],"ng/mL":[124],"16.8":[126],"(9.9)":[127],"ng/mL,":[128],"P=0.002).":[129],"After":[130,146],"adjusting":[131],"by":[132,175,185],"coffee":[135],"consumption,":[136],"female":[137],"had":[139],"urinary-NTX":[141],"smokers.":[145],"cessation,":[148],"statistically":[149],"significant":[150],"decreases":[151],"SHBG":[156],"observed":[160],"men":[162],"respectively.":[165],"CONCLUSIONS:":[166],"Tobacco":[167],"increases":[168],"resorption":[170],"affects":[172],"mass":[174],"some":[176],"alterations":[177,186],"hormone":[180],"metabolism,":[181],"also":[183],"importantly":[184],"axis.":[191]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}