{"id":"https://openalex.org/W164827933","doi":null,"title":"Effects of head-down bed rest & microgravity on renal fluid excretion.","display_name":"Effects of head-down bed rest & microgravity on renal fluid excretion.","publication_year":1998,"publication_date":"1998-07-01","ids":{"openalex":"https://openalex.org/W164827933","mag":"164827933","pmid":"https://pubmed.ncbi.nlm.nih.gov/11542375"},"language":"en","primary_location":{"id":"pmid:11542375","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11542375","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067272090","display_name":"Peter Norsk","orcid":"https://orcid.org/0000-0001-5821-9214","observed_orcids":["https://orcid.org/0000-0001-5821-9214"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Norsk","raw_affiliation_strings":["Danish Aerospace Medical Centre of Research, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Danish Aerospace Medical Centre of Research, Copenhagen, Denmark","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102722245","display_name":"Niels Juel Christensen","orcid":"https://orcid.org/0000-0002-2291-7886","observed_orcids":["https://orcid.org/0000-0002-2291-7886"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N J Christensen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023299145","display_name":"D. V. Vorobiev","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Vorobiev","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082035600","display_name":"Yoshio Suzuki","orcid":"https://orcid.org/0000-0003-4982-5591","observed_orcids":["https://orcid.org/0000-0003-4982-5591"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Suzuki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111466617","display_name":"C. Drummer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Drummer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5087443620","display_name":"Martina A. Heer","orcid":"https://orcid.org/0000-0001-5534-911X","observed_orcids":["https://orcid.org/0000-0001-5534-911X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Heer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"5","issue":"1","first_page":"P81","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14214","display_name":"Space Exploration and Technology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2202","display_name":"Aerospace Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/head-down-bed-rest","display_name":"head-down bed rest","score":0.8790000081062317},{"id":"https://openalex.org/keywords/microgravity","display_name":"microgravity","score":0.9929999709129333},{"id":"https://openalex.org/keywords/fluid-volume-regulation","display_name":"fluid volume regulation","score":0.9190000295639038},{"id":"https://openalex.org/keywords/supine-position","display_name":"supine position","score":0.7360000014305115},{"id":"https://openalex.org/keywords/intravascular-volume","display_name":"intravascular volume","score":0.9120000004768372},{"id":"https://openalex.org/keywords/fluid-retention","display_name":"fluid retention","score":0.9319999814033508},{"id":"https://openalex.org/keywords/spaceflight","display_name":"spaceflight","score":0.47699999809265137},{"id":"https://openalex.org/keywords/cardiovascular-regulation","display_name":"cardiovascular regulation","score":0.4970000088214874},{"id":"https://openalex.org/keywords/hormone-regulation","display_name":"hormonal regulation","score":0.7350000143051147},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.3330000042915344}],"concepts":[{"id":"https://openalex.org/C2910053146","wikidata":"https://www.wikidata.org/wiki/Q1742390","display_name":"Head-Down Tilt","level":3,"score":0.9403890371322632},{"id":"https://openalex.org/C125567185","wikidata":"https://www.wikidata.org/wiki/Q3267428","display_name":"Supine position","level":2,"score":0.9265035390853882},{"id":"https://openalex.org/C2777854218","wikidata":"https://www.wikidata.org/wiki/Q850197","display_name":"Bed rest","level":2,"score":0.8409017324447632},{"id":"https://openalex.org/C37752432","wikidata":"https://www.wikidata.org/wiki/Q4299309","display_name":"Weightlessness","level":2,"score":0.7825871706008911},{"id":"https://openalex.org/C2779844322","wikidata":"https://www.wikidata.org/wiki/Q2919140","display_name":"Tilt (camera)","level":2,"score":0.5400422811508179},{"id":"https://openalex.org/C2780312720","wikidata":"https://www.wikidata.org/wiki/Q5689100","display_name":"Head (geology)","level":2,"score":0.4486968517303467},{"id":"https://openalex.org/C103888896","wikidata":"https://www.wikidata.org/wiki/Q5916","display_name":"Spaceflight","level":2,"score":0.4403075575828552},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43595194816589355},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.38142406940460205},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.37538331747055054},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3574133515357971},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3245719075202942},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32367900013923645},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.22105970978736877},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12488630414009094},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.11381766200065613},{"id":"https://openalex.org/C114793014","wikidata":"https://www.wikidata.org/wiki/Q52109","display_name":"Geomorphology","level":1,"score":0.08828574419021606},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001510","descriptor_name":"Bed Rest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006112","descriptor_name":"Gravitation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006874","descriptor_name":"Hydrostatic Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010953","descriptor_name":"Plasma Volume","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011187","descriptor_name":"Posture","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012083","descriptor_name":"Renin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012083","descriptor_name":"Renin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D012965","descriptor_name":"Sodium Chloride","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013026","descriptor_name":"Space Flight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014882","descriptor_name":"Water-Electrolyte Balance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014893","descriptor_name":"Weightlessness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016683","descriptor_name":"Supine Position","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018475","descriptor_name":"Head-Down Tilt","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:11542375","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11542375","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology","raw_type":"Comparative Study"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/48096e0e-cde8-46d3-8c5f-4d3215ff0ccf","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/48096e0e-cde8-46d3-8c5f-4d3215ff0ccf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Norsk, P, Christensen, N J, Vorobiev, D, Suzuki, Y, Drummer, C & Heer, M 1998, 'Effects of head-down bed rest & microgravity on renal fluid excretion', Journal of Gravitational Physiology, vol. 5, no. 1, pp. P81-4.","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:164827933","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11542375","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8999999761581421}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2471351322","https://openalex.org/W2014421992","https://openalex.org/W2070621883","https://openalex.org/W1991355617","https://openalex.org/W854618546","https://openalex.org/W808688312","https://openalex.org/W2041467406","https://openalex.org/W126574298","https://openalex.org/W7155374854","https://openalex.org/W2991762862"],"abstract_inverted_index":{"The":[0],"significance":[1],"of":[2,62,72,99],"transverse":[3,43],"gravity":[4],"stress":[5],"on":[6,15,39,59],"fluid":[7,100],"volume":[8,85],"regulation":[9],"in":[10,24,45,83,97],"supine":[11,46],"humans":[12,51],"was":[13],"studied":[14],"the":[16,40,42,60,73,87],"D2":[17],"Spacelab":[18],"mission,":[19,22],"a":[20,25,53,79],"Mir":[21],"and":[23,66],"head-down":[26,49,92],"tilt":[27],"bed":[28,93],"rest":[29],"study.":[30],"A":[31],"new":[32],"hypothesis":[33],"is":[34],"presented":[35],"which":[36,95],"states":[37],"that":[38],"ground,":[41],"G-stress":[44,74],"or":[47],"slightly":[48],"tilted":[50],"has":[52],"more":[54,80],"pronounced":[55,81],"effect":[56],"than":[57,86],"anticipated":[58],"interaction":[61],"central":[63],"cardiovascular,":[64],"endocrine,":[65],"renal":[67],"variables.":[68],"Also,":[69],"total":[70],"abolishment":[71],"during":[75],"space":[76],"flight":[77],"induces":[78],"decrease":[82,88],"intravascular":[84],"induced":[89],"by":[90],"prolonged":[91],"rest,":[94],"results":[96],"stimulation":[98],"retaining":[101],"mechanisms.":[102]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}