{"id":"https://openalex.org/W1633779121","doi":"https://doi.org/10.1016/s0016-5085(13)61010-0","title":"Sa1697 Progressive Loss of ARID1A (P270) Expression During Early Stages of Colorectal Carcinogenesis Is a Significant Determinant of the Colonic Epithelium Phenotype","display_name":"Sa1697 Progressive Loss of ARID1A (P270) Expression During Early Stages of Colorectal Carcinogenesis Is a Significant Determinant of the Colonic Epithelium Phenotype","publication_year":2013,"publication_date":"2013-05-01","ids":{"openalex":"https://openalex.org/W1633779121","doi":"https://doi.org/10.1016/s0016-5085(13)61010-0","mag":"1633779121"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(13)61010-0","doi":"https://doi.org/10.1016/s0016-5085(13)61010-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(13)61010-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051201314","display_name":"Ashish K. Tiwari","orcid":"https://orcid.org/0000-0002-0167-3165","observed_orcids":["https://orcid.org/0000-0002-0167-3165"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ashish K. Tiwari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111711810","display_name":"Ramesh K. Wali","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ramesh K. Wali","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004008868","display_name":"Vadim Backman","orcid":"https://orcid.org/0000-0003-1981-1818","observed_orcids":["https://orcid.org/0000-0003-1981-1818"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vadim Backman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5062415571","display_name":"Hemant K. Roy","orcid":"https://orcid.org/0000-0002-6342-6768","observed_orcids":["https://orcid.org/0000-0002-6342-6768","https://orcid.org/0000-0001-7613-5575"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hemant K. Roy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"144","issue":"5","first_page":"S","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.014999999664723873,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arid1a","display_name":"ARID1A","score":0.9950000047683716},{"id":"https://openalex.org/keywords/colorectal-carcinogenesis","display_name":"colorectal carcinogenesis","score":0.9419999718666077},{"id":"https://openalex.org/keywords/gene-expression-loss","display_name":"gene expression loss","score":0.7440000176429749},{"id":"https://openalex.org/keywords/early-colorectal-cancer","display_name":"early colorectal cancer","score":0.7099999785423279},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.5799999833106995},{"id":"https://openalex.org/keywords/colorectal-adenoma","display_name":"colorectal adenoma","score":0.574999988079071}],"concepts":[{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.7263084650039673},{"id":"https://openalex.org/C2781273526","wikidata":"https://www.wikidata.org/wiki/Q18032797","display_name":"ARID1A","level":4,"score":0.669306755065918},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.6553855538368225},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.6120107769966125},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5593358874320984},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.49822068214416504},{"id":"https://openalex.org/C3020179232","wikidata":"https://www.wikidata.org/wiki/Q11083","display_name":"Distal colon","level":2,"score":0.47488826513290405},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43845808506011963},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3963894248008728},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3940739035606384},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2949676811695099},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20105063915252686},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.14219778776168823},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13095983862876892},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.11383593082427979}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(13)61010-0","doi":"https://doi.org/10.1016/s0016-5085(13)61010-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(13)61010-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7207948066","https://openalex.org/W7208130443","https://openalex.org/W3047241904","https://openalex.org/W2111334114","https://openalex.org/W2289373890","https://openalex.org/W7133486170","https://openalex.org/W2198543334","https://openalex.org/W2019672863","https://openalex.org/W4213301892","https://openalex.org/W2800791360"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}