{"id":"https://openalex.org/W163218510","doi":null,"title":"Osteocalcin and type 2 diabetes mellitus","display_name":"Osteocalcin and type 2 diabetes mellitus","publication_year":2014,"publication_date":"2014-12-12","ids":{"openalex":"https://openalex.org/W163218510","mag":"163218510"},"language":"en","primary_location":{"id":"pmh:oai:medlib.mef.hr:2181","doi":null,"is_oa":true,"landing_page_url":"http://medlib.mef.hr/2181/1/Berisha-Muharremi_V_disertacija_rep_2181.pdf","pdf_url":"http://medlib.mef.hr/2181/1/Berisha-Muharremi_V_disertacija_rep_2181.pdf","source":{"id":"https://openalex.org/S4306401735","display_name":"Repository of the Medical Faculty of the University of Zagreb (University of Zagreb)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I181343428","host_organization_name":"University of Zagreb","host_organization_lineage":["https://openalex.org/I181343428"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://medlib.mef.hr/2181/1/Berisha-Muharremi_V_disertacija_rep_2181.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006906898","display_name":"Venera Berisha\u2010Muharremi","orcid":"https://orcid.org/0000-0003-1153-9872","observed_orcids":["https://orcid.org/0000-0003-1153-9872"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Berisha-Muharremi, Venera","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5006906898"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.6484000086784363,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.6484000086784363,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.16769999265670776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.03869999945163727,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/undercarboxylated-osteocalcin","display_name":"undercarboxylated osteocalcin","score":0.9570000171661377},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9890000224113464},{"id":"https://openalex.org/keywords/newly-diagnosed-diabetes","display_name":"newly diagnosed diabetes","score":0.7670000195503235},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.9229999780654907},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.9909999966621399},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.9639999866485596},{"id":"https://openalex.org/keywords/lifestyle-intervention","display_name":"lifestyle intervention","score":0.6029999852180481},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8899999856948853},{"id":"https://openalex.org/keywords/homa-ir","display_name":"HOMA-IR","score":0.9399999976158142},{"id":"https://openalex.org/keywords/homa-beta","display_name":"HOMA-\u03b2","score":0.7059999704360962},{"id":"https://openalex.org/keywords/bone-turnover","display_name":"bone turnover","score":0.7289999723434448},{"id":"https://openalex.org/keywords/glucose-metabolism","display_name":"glucose metabolism","score":0.75}],"concepts":[{"id":"https://openalex.org/C131075544","wikidata":"https://www.wikidata.org/wiki/Q415863","display_name":"Osteocalcin","level":4,"score":0.8070365190505981},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7842603325843811},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5886476039886475},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.532094419002533},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.5143169164657593},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.47802600264549255},{"id":"https://openalex.org/C206041023","wikidata":"https://www.wikidata.org/wiki/Q1751970","display_name":"Wilcoxon signed-rank test","level":3,"score":0.4433203339576721},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.4355922341346741},{"id":"https://openalex.org/C17093226","wikidata":"https://www.wikidata.org/wiki/Q2734081","display_name":"Carbohydrate metabolism","level":2,"score":0.41426628828048706},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4113621115684509},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10983365774154663},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.10462480783462524},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C12868164","wikidata":"https://www.wikidata.org/wiki/Q1424533","display_name":"Mann\u2013Whitney U test","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:medlib.mef.hr:2181","doi":null,"is_oa":true,"landing_page_url":"http://medlib.mef.hr/2181/1/Berisha-Muharremi_V_disertacija_rep_2181.pdf","pdf_url":"http://medlib.mef.hr/2181/1/Berisha-Muharremi_V_disertacija_rep_2181.pdf","source":{"id":"https://openalex.org/S4306401735","display_name":"Repository of the Medical Faculty of the University of Zagreb (University of Zagreb)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I181343428","host_organization_name":"University of Zagreb","host_organization_lineage":["https://openalex.org/I181343428"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"}],"best_oa_location":{"id":"pmh:oai:medlib.mef.hr:2181","doi":null,"is_oa":true,"landing_page_url":"http://medlib.mef.hr/2181/1/Berisha-Muharremi_V_disertacija_rep_2181.pdf","pdf_url":"http://medlib.mef.hr/2181/1/Berisha-Muharremi_V_disertacija_rep_2181.pdf","source":{"id":"https://openalex.org/S4306401735","display_name":"Repository of the Medical Faculty of the University of Zagreb (University of Zagreb)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I181343428","host_organization_name":"University of Zagreb","host_organization_lineage":["https://openalex.org/I181343428"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W163218510.pdf","grobid_xml":"https://content.openalex.org/works/W163218510.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1963690512","https://openalex.org/W1974972250","https://openalex.org/W1980740451","https://openalex.org/W1986157894","https://openalex.org/W1989889975","https://openalex.org/W2004115712","https://openalex.org/W2005571342","https://openalex.org/W2008699478","https://openalex.org/W2019258161","https://openalex.org/W2022633145","https://openalex.org/W2022739340","https://openalex.org/W2038553863","https://openalex.org/W2044626025","https://openalex.org/W2046861848","https://openalex.org/W2047761422","https://openalex.org/W2049254268","https://openalex.org/W2052383327","https://openalex.org/W2057213665","https://openalex.org/W2058705700","https://openalex.org/W2059158127","https://openalex.org/W2059766545","https://openalex.org/W2067513456","https://openalex.org/W2069453819","https://openalex.org/W2087195975","https://openalex.org/W2095543479","https://openalex.org/W2097802491","https://openalex.org/W2101422068","https://openalex.org/W2106118214","https://openalex.org/W2107797783","https://openalex.org/W2114528551","https://openalex.org/W2115819754","https://openalex.org/W2116854676","https://openalex.org/W2123306045","https://openalex.org/W2128714854","https://openalex.org/W2131814354","https://openalex.org/W2137024891","https://openalex.org/W2155772175","https://openalex.org/W2160234571","https://openalex.org/W2163582576","https://openalex.org/W2166142060","https://openalex.org/W2170271198","https://openalex.org/W2171294019","https://openalex.org/W2232407802","https://openalex.org/W2337454357","https://openalex.org/W3023173633"],"related_works":["https://openalex.org/W2525049887","https://openalex.org/W2125293496","https://openalex.org/W4321494896","https://openalex.org/W2009547701","https://openalex.org/W2922096605","https://openalex.org/W4210486935","https://openalex.org/W2466391633","https://openalex.org/W1986157894","https://openalex.org/W1518754879","https://openalex.org/W3136685045"],"abstract_inverted_index":{"Introduction:":[0],"From":[1],"year":[2],"2007.":[3],"in":[4,7,18,43,170,186],"vitro":[5],"and":[6,20,38,49,58,98,106,129,131,137,172,177,209],"vivo":[8],"studies":[9],"have":[10],"suggested":[11],"a":[12,69,183],"role":[13],"of":[14,27,35,95,127],"undercarboxylated":[15],"osteocalcin":[16],"(ucOC)":[17],"glucose":[19,40,207],"energy":[21],"metabolism.":[22],"-----":[23,56,108,196],"Aims:":[24],"The":[25,84,223],"aim":[26],"the":[28,33,114,121,203,232],"study":[29,199],"was":[30,82,88,133,155,179,182],"to":[31,142,145,162,194,201],"investigate":[32],"relationship":[34,204],"ucOC":[36,128,154,173,210],"level":[37],"blood":[39,206],"(BG)":[41],"control":[42,54,241],"newly":[44,62],"diagnosed":[45,63],"type":[46,64],"2":[47,65,178],"diabetes":[48],"its":[50],"change":[51,185],"with":[52,235],"BG":[53,79,96,240],"improvement.":[55],"Subjects":[57],"methods:":[59],"Fifty":[60],"seven":[61,111],"diabetic":[66],"patients":[67,112,119,230],"had":[68],"consultation":[70],"about":[71],"life":[72],"style":[73],"changes":[74],"on":[75,103],"visit":[76,86,104],"1,":[77],"no":[78,236],"regulation":[80,208],"medication":[81],"prescribed.":[83],"final":[85],"(2)":[87],"three":[89],"months":[90],"later.":[91],"Samples":[92],"for":[93],"parameters":[94],"metabolism":[97],"bone":[99],"turnover":[100],"were":[101],"collected":[102],"1":[105,176],"2.":[107],"Results:":[109],"Forty":[110],"completed":[113],"study.":[115],"Thirty":[116],"two":[117],"(56%)":[118],"reached":[120],"target":[122,233],"HbA1c":[123,130,136,171,234],"(\u22647%).":[124],"No":[125,166],"correlation":[126,167],"FBG":[132,138],"observed.":[134],"Median":[135],"changed":[139],"significantly":[140,159],"(8.0":[141],"6.5%;":[143],"9.0":[144],"7.0":[146],"mmol/L":[147],"resp.;":[148],"Wilcoxon":[149],"signed":[150],"rank":[151],"test":[152],"p<0.001),":[153],"slightly":[156],"but":[157,188],"not":[158,189,192,215],"lower":[160],"(2.0":[161],"1.4":[163],"mcg/L;":[164],"p=0.465).":[165],"between":[168,174,205],"differences":[169],"Visits":[175],"revealed.":[180],"There":[181],"significant":[184],"HOMA%B":[187],"HOMA":[190],"IR,":[191],"correlated":[193],"ucOC.":[195],"Conclusion:":[197],"This":[198],"failed":[200],"prove":[202],"level.":[211],"However,":[212],"it":[213],"does":[214],"exclude":[216],"it,":[217],"so":[218],"further":[219],"research":[220],"is":[221],"needed.":[222],"fact":[224],"that":[225],"as":[226,228],"much":[227],"56%":[229],"achieved":[231],"medication,":[237],"challenges":[238],"most":[239],"guidelines.":[242]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}